Comparative magnetic resonance imaging and histopathological correlates in two SOD1 transgenic mouse models of amyotrophic lateral sclerosis

PLoS ONE

Volumn 10, Issue 7, 2015, Pages

  Caron, Ilaria ^a   Micotti, Edoardo ^a   Paladini, Alessandra ^a   Merlino, Giuseppe ^a   Plebani, Laura ^a   Forloni, Gianluigi ^a   Modo, Michel ^b   Bendotti, Caterina ^a  

^a MARIO NEGRI INSTITUTE FOR PHARMACOLOGICAL RESEARCH   (Italy)

^b UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; COPPER ZINC SUPEROXIDE DISMUTASE; RECOMBINANT PROTEIN; SOD1 PROTEIN, HUMAN; SOD1 PROTEIN, MOUSE; SUPEROXIDE DISMUTASE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN STEM; CELL VACUOLE; CONTROLLED STUDY; CRANIAL NERVE; DIFFUSION TENSOR IMAGING; DISEASE SEVERITY; EX VIVO STUDY; FEMALE; GRIP STRENGTH; HISTOPATHOLOGY; IN VIVO STUDY; INTERMETHOD COMPARISON; LONGITUDINAL STUDY; LUMBAR SPINAL CORD; MOTONEURON; MOUSE; MSOD1 MOUSE; NERVE FIBER DEGENERATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PHENOTYPE; PROGNOSIS; VALIDATION PROCESS; WHITE MATTER; 129 MOUSE; AMINO ACID SUBSTITUTION; ANIMAL; AXON; C57BL MOUSE; COMPARATIVE STUDY; DISEASE COURSE; GENETICS; HAND STRENGTH; HUMAN; LUMBOSACRAL REGION; MISSENSE MUTATION; PATHOLOGY; POINT MUTATION; PROCEDURES; RANDOMIZATION; SPINAL CORD; TRANSGENIC MOUSE; ULTRASTRUCTURE;

MUS; MUS MUSCULUS;

AMINO ACID SUBSTITUTION; AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; AXONS; BRAIN STEM; DIFFUSION TENSOR IMAGING; DISEASE PROGRESSION; HAND STRENGTH; HUMANS; LUMBOSACRAL REGION; MAGNETIC RESONANCE IMAGING; MICE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, TRANSGENIC; MOTOR NEURONS; MUTATION, MISSENSE; POINT MUTATION; RANDOM ALLOCATION; RECOMBINANT PROTEINS; SPINAL CORD; SUPEROXIDE DISMUTASE; SUPEROXIDE DISMUTASE-1; VACUOLES; WHITE MATTER;

EID: 84938872961     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0132159     Document Type: Article

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