-
1
-
-
78650323671
-
Predictive, preventive, personalized and participatory medicine: Back to the future
-
Auffray, C., Charron, D., and Hood, L. (2010). Predictive, preventive, personalized and participatory medicine: back to the future. Genome Med. 2, 57.
-
(2010)
Genome Med.
, vol.2
, pp. 57
-
-
Auffray, C.1
Charron, D.2
Hood, L.3
-
2
-
-
79951596067
-
Targeting the unfolded protein response in cancer therapy
-
Backer, M.V., Backer, J.M., and Chinnaiyan, P. (2011). Targeting the unfolded protein response in cancer therapy. Methods Enzymol. 491, 37-56.
-
(2011)
Methods Enzymol.
, vol.491
, pp. 37-56
-
-
Backer, M.V.1
Backer, J.M.2
Chinnaiyan, P.3
-
3
-
-
77951568703
-
Phosphoinositide signalling in cancer: Beyond PI3K and PTEN
-
Bunney, T.D., and Katan, M. (2010). Phosphoinositide signalling in cancer: beyond PI3K and PTEN. Nat. Rev. Cancer 10, 342-352.
-
(2010)
Nat. Rev. Cancer
, vol.10
, pp. 342-352
-
-
Bunney, T.D.1
Katan, M.2
-
5
-
-
84860857365
-
Interactions of nucleolin and ribosomal protein L26 (RPL26) in translational control of human p53 mRNA
-
Chen, J., Guo, K., and Kastan, M.B. (2012a). Interactions of nucleolin and ribosomal protein L26 (RPL26) in translational control of human p53 mRNA. J. Biol. Chem. 287, 16467-16476.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 16467-16476
-
-
Chen, J.1
Guo, K.2
Kastan, M.B.3
-
6
-
-
84859741480
-
Detecting early-warning signals for sudden deterioration of complex diseases by dynamical network biomarkers
-
Chen, L., Liu, R., Liu, Z.P., et al. (2012b). Detecting early-warning signals for sudden deterioration of complex diseases by dynamical network biomarkers. Sci. Rep. 2, 342.
-
(2012)
Sci. Rep.
, vol.2
, pp. 342
-
-
Chen, L.1
Liu, R.2
Liu, Z.P.3
-
8
-
-
84861892842
-
Frameshift mutation in p53 regulator RPL26 is associated with multiple physical abnormalities and a specific pre-ribosomal RNA processing defect in diamond-blackfan anemia
-
Gazda, H.T., Preti, M., Sheen, M.R., et al. (2012). Frameshift mutation in p53 regulator RPL26 is associated with multiple physical abnormalities and a specific pre-ribosomal RNA processing defect in diamond-blackfan anemia. Hum. Mutat. 33, 1037-1044.
-
(2012)
Hum. Mutat.
, vol.33
, pp. 1037-1044
-
-
Gazda, H.T.1
Preti, M.2
Sheen, M.R.3
-
9
-
-
84861893428
-
Coexpression network analysis in chronic hepatitis B and C hepatic lesions reveals distinct patterns of disease progression to hepatocellular carcinoma
-
He, D., Liu, Z.P., Honda, M., et al. (2012). Coexpression network analysis in chronic hepatitis B and C hepatic lesions reveals distinct patterns of disease progression to hepatocellular carcinoma. J. Mol. Cell Biol. 4, 140-152.
-
(2012)
J. Mol. Cell Biol.
, vol.4
, pp. 140-152
-
-
He, D.1
Liu, Z.P.2
Honda, M.3
-
10
-
-
52649131951
-
Lung cancer
-
Herbst, R.S., Heymach, J.V., and Lippman, S.M. (2008). Lung cancer. N. Engl. J. Med. 359, 1367-1380.
-
(2008)
N. Engl. J. Med.
, vol.359
, pp. 1367-1380
-
-
Herbst, R.S.1
Heymach, J.V.2
Lippman, S.M.3
-
11
-
-
84865429505
-
A personal view on systems medicine and the emergence of proactive P4 medicine: Predictive, preventive, personalized and participatory
-
Hood, L., and Flores, M. (2012). A personal view on systems medicine and the emergence of proactive P4 medicine: predictive, preventive, personalized and participatory. N. Biotechnol. 29, 613-624.
-
(2012)
N. Biotechnol.
, vol.29
, pp. 613-624
-
-
Hood, L.1
Flores, M.2
-
12
-
-
79952431304
-
Predictive, personalized, preventive, participatory (P4) cancer medicine
-
Hood, L., and Friend, S.H. (2011). Predictive, personalized, preventive, participatory (P4) cancer medicine. Nat. Rev. Clin. Oncol. 8, 184-187.
-
(2011)
Nat. Rev. Clin. Oncol.
, vol.8
, pp. 184-187
-
-
Hood, L.1
Friend, S.H.2
-
13
-
-
40449105942
-
An actin-binding protein Girdin regulates the motility of breast cancer cells
-
Jiang, P., Enomoto, A., Jijiwa, M., etal. (2008). An actin-binding protein Girdin regulates the motility of breast cancer cells. Cancer Res. 68, 1310-1318.
-
(2008)
Cancer Res.
, vol.68
, pp. 1310-1318
-
-
Jiang, P.1
Enomoto, A.2
Jijiwa, M.3
-
14
-
-
33749028188
-
Vascular endothelial growth factor signaling pathways: Therapeutic perspective
-
Kowanetz, M., and Ferrara, N. (2006). Vascular endothelial growth factor signaling pathways: therapeutic perspective. Clin. Cancer Res. 12, 5018-5022.
-
(2006)
Clin. Cancer Res.
, vol.12
, pp. 5018-5022
-
-
Kowanetz, M.1
Ferrara, N.2
-
15
-
-
33644878620
-
DBD: A transcription factor prediction database
-
Kummerfeld, S.K., and Teichmann, S.A. (2006). DBD: a transcription factor prediction database. Nucleic Acids Res. 34, D74-D81.
-
(2006)
Nucleic Acids Res.
, vol.34
, pp. D74-D81
-
-
Kummerfeld, S.K.1
Teichmann, S.A.2
-
16
-
-
10244219943
-
A statistical method for identifying differential gene-gene co-expression patterns
-
Lai, Y., Wu, B., Chen, L., et al. (2004). A statistical method for identifying differential gene-gene co-expression patterns. Bioinformatics 20, 3146-3155.
-
(2004)
Bioinformatics
, vol.20
, pp. 3146-3155
-
-
Lai, Y.1
Wu, B.2
Chen, L.3
-
17
-
-
0025880144
-
Changes in inositol phosphate metabolism are associated with terminal differentiation and neoplasia in mouse keratinocytes
-
Lee, E., and Yuspa, S.H. (1991). Changes in inositol phosphate metabolism are associated with terminal differentiation and neoplasia in mouse keratinocytes. Carcinogenesis 12, 1651-1658.
-
(1991)
Carcinogenesis
, vol.12
, pp. 1651-1658
-
-
Lee, E.1
Yuspa, S.H.2
-
18
-
-
84867330886
-
Silencing expression of ribosomal protein L26 and L29 by RNA interfering inhibits proliferation of human pancreatic cancer PANC-1 cells
-
Li, C., Ge, M., Yin, Y., et al. (2012). Silencing expression of ribosomal protein L26 and L29 by RNA interfering inhibits proliferation of human pancreatic cancer PANC-1 cells. Mol. Cell. Biochem. 370, 127-139.
-
(2012)
Mol. Cell. Biochem.
, vol.370
, pp. 127-139
-
-
Li, C.1
Ge, M.2
Yin, Y.3
-
19
-
-
84883614821
-
Sulindac selectively inhibits colon tumor cell growth by activating the cGMP/PKG pathway to suppress Wnt/beta-catenin signaling
-
Li, N., Xi, Y., Tinsley, H.N., et al. (2013). Sulindac selectively inhibits colon tumor cell growth by activating the cGMP/PKG pathway to suppress Wnt/beta-catenin signaling. Mol. Cancer Ther. 12, 1848-1859.
-
(2013)
Mol. Cancer Ther.
, vol.12
, pp. 1848-1859
-
-
Li, N.1
Xi, Y.2
Tinsley, H.N.3
-
20
-
-
84902325763
-
ZNF139 promotes tumor metastasis by increasing migration and invasion in human gastric cancer cells
-
Li, Y., Tan, B.B., Zhao, Q., et al. (2014). ZNF139 promotes tumor metastasis by increasing migration and invasion in human gastric cancer cells. Neoplasma 61, 291-298.
-
(2014)
Neoplasma
, vol.61
, pp. 291-298
-
-
Li, Y.1
Tan, B.B.2
Zhao, Q.3
-
21
-
-
33846651082
-
Difference detection in LC-MS data for protein biomarker discovery
-
Listgarten, J., Neal, R.M., Roweis, S.T., et al. (2007). Difference detection in LC-MS data for protein biomarker discovery. Bioinformatics 23, e198-e204.
-
(2007)
Bioinformatics
, vol.23
, pp. e198-e204
-
-
Listgarten, J.1
Neal, R.M.2
Roweis, S.T.3
-
22
-
-
84871750865
-
Identifying critical transitions and their leading biomolecular networks in complex diseases
-
Liu, R., Li, M., Liu, Z.P., et al. (2012a). Identifying critical transitions and their leading biomolecular networks in complex diseases. Sci. Rep. 2, 813.
-
(2012)
Sci. Rep.
, vol.2
, pp. 813
-
-
Liu, R.1
Li, M.2
Liu, Z.P.3
-
23
-
-
84863128658
-
Identifying disease genes and module biomarkers by differential interactions
-
Liu, X., Liu, Z.P., Zhao, X.M., et al. (2012b). Identifying disease genes and module biomarkers by differential interactions. J. Am. Med. Inform. Assoc. 19, 241-248.
-
(2012)
J. Am. Med. Inform. Assoc.
, vol.19
, pp. 241-248
-
-
Liu, X.1
Liu, Z.P.2
Zhao, X.M.3
-
24
-
-
84901315597
-
Identifying critical transitions of complex diseases based on a single sample
-
Liu, R., Yu, X., Liu, X., et al. (2014). Identifying critical transitions of complex diseases based on a single sample. Bioinformatics 30, 1579-1586.
-
(2014)
Bioinformatics
, vol.30
, pp. 1579-1586
-
-
Liu, R.1
Yu, X.2
Liu, X.3
-
25
-
-
10344222124
-
The role of the unfolded protein response in tumour development: Friend or foe?
-
Ma, Y., and Hendershot, L.M. (2004). The role of the unfolded protein response in tumour development: friend or foe? Nat. Rev. Cancer 4, 966-977.
-
(2004)
Nat. Rev. Cancer
, vol.4
, pp. 966-977
-
-
Ma, Y.1
Hendershot, L.M.2
-
26
-
-
19644388098
-
Serum protein markers for early detection of ovarian cancer
-
Mor, G., Visintin, I., Lai, Y., et al. (2005). Serum protein markers for early detection of ovarian cancer. Proc. Natl Acad. Sci. USA 102, 7677-7682.
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, pp. 7677-7682
-
-
Mor, G.1
Visintin, I.2
Lai, Y.3
-
27
-
-
53949121380
-
Mdm2 regulates p53 mRNA translation through inhibitory interactions with ribosomal protein L26
-
Ofir-Rosenfeld, Y., Boggs, K., Michael, D., et al. (2008). Mdm2 regulates p53 mRNA translation through inhibitory interactions with ribosomal protein L26. Mol. Cell 32, 180-189.
-
(2008)
Mol. Cell
, vol.32
, pp. 180-189
-
-
Ofir-Rosenfeld, Y.1
Boggs, K.2
Michael, D.3
-
28
-
-
78049464333
-
Calcium wave signaling in cancer cells
-
Parkash, J., and Asotra, K. (2010). Calcium wave signaling in cancer cells. Life Sci. 87, 587-595.
-
(2010)
Life Sci.
, vol.87
, pp. 587-595
-
-
Parkash, J.1
Asotra, K.2
-
29
-
-
0031397808
-
The cadherin cell-cell adhesion pathway in prostate cancer progression
-
Paul, R., Ewing, C.M., Jarrard, D.F., et al. (1997). The cadherin cell-cell adhesion pathway in prostate cancer progression. Br. J. Urol. 79(Suppl 1), 37-43.
-
(1997)
Br. J. Urol.
, vol.79
, pp. 37-43
-
-
Paul, R.1
Ewing, C.M.2
Jarrard, D.F.3
-
30
-
-
79960759956
-
Calcium in tumour metastasis: New roles for known actors
-
Prevarskaya, N., Skryma, R., and Shuba, Y. (2011). Calcium in tumour metastasis: new roles for known actors. Nat. Rev. Cancer 11, 609-618.
-
(2011)
Nat. Rev. Cancer
, vol.11
, pp. 609-618
-
-
Prevarskaya, N.1
Skryma, R.2
Shuba, Y.3
-
31
-
-
0028547556
-
Floating search methods in feature-selection
-
Pudil, P., Novovicova, J., and Kittler, J. (1994). Floating search methods in feature-selection. Pattern Recognit. Lett. 15, 1119-1125.
-
(1994)
Pattern Recognit. Lett.
, vol.15
, pp. 1119-1125
-
-
Pudil, P.1
Novovicova, J.2
Kittler, J.3
-
32
-
-
84907190913
-
Essential role of the cGMP/PKG signaling pathway in regulating the proliferation and survival of human renal carcinoma cells
-
Ren, Y., Zheng, J., Yao, X., et al. (2014). Essential role of the cGMP/PKG signaling pathway in regulating the proliferation and survival of human renal carcinoma cells. Int. J. Mol. Med. 34, 1430-1438.
-
(2014)
Int. J. Mol. Med.
, vol.34
, pp. 1430-1438
-
-
Ren, Y.1
Zheng, J.2
Yao, X.3
-
33
-
-
74949118681
-
The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5
-
Rouschop, K.M.A., van den Beucken, T., Dubois, L., et al. (2010). The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5. J. Clin. Invest. 120, 127-141.
-
(2010)
J. Clin. Invest.
, vol.120
, pp. 127-141
-
-
Rouschop, K.M.A.1
Van Den Beucken, T.2
Dubois, L.3
-
34
-
-
79960840508
-
Sulfur amino acid metabolism in doxorubicin-resistant breast cancer cells
-
Ryu, C.S., Kwak, H.C., Lee, K.S., et al. (2011). Sulfur amino acid metabolism in doxorubicin-resistant breast cancer cells. Toxicol. Appl. Pharmacol. 255, 94-102.
-
(2011)
Toxicol. Appl. Pharmacol.
, vol.255
, pp. 94-102
-
-
Ryu, C.S.1
Kwak, H.C.2
Lee, K.S.3
-
35
-
-
84889606541
-
Edgotype: A fundamental link between genotype and phenotype
-
Sahni, N., Yi, S., Zhong, Q., et al. (2013). Edgotype: a fundamental link between genotype and phenotype. Curr. Opin. Genet. Dev. 23, 649-657.
-
(2013)
Curr. Opin. Genet. Dev.
, vol.23
, pp. 649-657
-
-
Sahni, N.1
Yi, S.2
Zhong, Q.3
-
36
-
-
84887828585
-
Spatio-temporal analysis of type 2 diabetes mellitus based on differential expression networks
-
Sun, S.Y., Liu, Z.P., Zeng, T., et al. (2013). Spatio-temporal analysis of type 2 diabetes mellitus based on differential expression networks. Sci. Rep. 3, 2268.
-
(2013)
Sci. Rep.
, vol.3
, pp. 2268
-
-
Sun, S.Y.1
Liu, Z.P.2
Zeng, T.3
-
37
-
-
67649965344
-
Relapse-related molecular signature in lung adenocarcinomas identifies patients with dismal prognosis
-
Tomida, S., Takeuchi, T., Shimada, Y., et al. (2009). Relapse-related molecular signature in lung adenocarcinomas identifies patients with dismal prognosis. J. Clin. Oncol. 27, 2793-2799.
-
(2009)
J. Clin. Oncol.
, vol.27
, pp. 2793-2799
-
-
Tomida, S.1
Takeuchi, T.2
Shimada, Y.3
-
38
-
-
0036632368
-
The phosphatidylinositol 3-Kinase AKT pathway in human cancer
-
Vivanco, I., and Sawyers, C.L. (2002). The phosphatidylinositol 3-Kinase AKT pathway in human cancer. Nat. Rev. Cancer 2, 489-501.
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 489-501
-
-
Vivanco, I.1
Sawyers, C.L.2
-
39
-
-
0242526048
-
Cancer inhibition by inositol hexaphosphate (IP6) and inositol: From laboratory to clinic
-
Vucenik, I., and Shamsuddin, A.M. (2003). Cancer inhibition by inositol hexaphosphate (IP6) and inositol: from laboratory to clinic. J. Nutr. 133, 3778S-3784S.
-
(2003)
J. Nutr.
, vol.133
, pp. 3778S-3784S
-
-
Vucenik, I.1
Shamsuddin, A.M.2
-
40
-
-
84855880717
-
Targeting the VEGF signaling pathway in cancer therapy
-
Waldner, M.J., and Neurath, M.F. (2012). Targeting the VEGF signaling pathway in cancer therapy. Expert Opin. Ther. Targets 16, 5-13.
-
(2012)
Expert Opin. Ther. Targets
, vol.16
, pp. 5-13
-
-
Waldner, M.J.1
Neurath, M.F.2
-
41
-
-
80052215666
-
NOA: A novel Network Ontology Analysis method
-
Wang, J., Huang, Q., Liu, Z.P., et al. (2011). NOA: a novel Network Ontology Analysis method. Nucleic Acids Res. 39, e187.
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. e187
-
-
Wang, J.1
Huang, Q.2
Liu, Z.P.3
-
42
-
-
84873124804
-
APG: An Active Protein-Gene network model to quantify regulatory signals in complex biological systems
-
Wang, J., Sun, Y., Zheng, S., et al. (2013). APG: an Active Protein-Gene network model to quantify regulatory signals in complex biological systems. Sci. Rep. 3, 1097.
-
(2013)
Sci. Rep.
, vol.3
, pp. 1097
-
-
Wang, J.1
Sun, Y.2
Zheng, S.3
-
43
-
-
81255188940
-
Tumor angiogenesis: Molecular pathways and therapeutic targets
-
Weis, S.M., and Cheresh, D.A. (2011). Tumor angiogenesis: molecular pathways and therapeutic targets. Nat. Med. 17, 1359-1370.
-
(2011)
Nat. Med.
, vol.17
, pp. 1359-1370
-
-
Weis, S.M.1
Cheresh, D.A.2
-
44
-
-
83655165720
-
Regulation of calcium signaling in lung cancer
-
Yang, H., Zhang, Q., He, J., et al. (2010). Regulation of calcium signaling in lung cancer. J. Thorac. Dis. 2, 52-56.
-
(2010)
J. Thorac. Dis.
, vol.2
, pp. 52-56
-
-
Yang, H.1
Zhang, Q.2
He, J.3
-
45
-
-
84897903348
-
Prediction and early diagnosis of complex diseases by edge-network
-
Yu, X., Li, G., and Chen, L. (2014). Prediction and early diagnosis of complex diseases by edge-network. Bioinformatics 30, 852-859.
-
(2014)
Bioinformatics
, vol.30
, pp. 852-859
-
-
Yu, X.1
Li, G.2
Chen, L.3
-
46
-
-
84887815759
-
Network biomarkers reveal dysfunctional gene regulations during disease progression
-
Zeng, T., Sun, S.Y., Wang, Y., et al. (2013). Network biomarkers reveal dysfunctional gene regulations during disease progression. FEBS J. 280, 5682-5695.
-
(2013)
FEBS J.
, vol.280
, pp. 5682-5695
-
-
Zeng, T.1
Sun, S.Y.2
Wang, Y.3
-
47
-
-
84922004018
-
Edge biomarkers for classification and prediction of phenotypes
-
Zeng, T., Zhang, W., Yu, X., et al. (2014). Edge biomarkers for classification and prediction of phenotypes. Sci. China Life Sci. 57, 1103-1114.
-
(2014)
Sci. China Life Sci.
, vol.57
, pp. 1103-1114
-
-
Zeng, T.1
Zhang, W.2
Yu, X.3
-
48
-
-
84907653864
-
EdgeMarker: Identifying differentially correlated molecule pairs as edge-biomarkers
-
Zhang, W., Zeng, T., and Chen, L. (2014). EdgeMarker: identifying differentially correlated molecule pairs as edge-biomarkers. J. Theor. Biol. 362, 35-43.
-
(2014)
J. Theor. Biol.
, vol.362
, pp. 35-43
-
-
Zhang, W.1
Zeng, T.2
Chen, L.3
|