-
2
-
-
76749147303
-
Chemo-immunotherapy in RCC: The end of a story
-
Escudier B: Chemo-immunotherapy in RCC: the end of a story. Lancet 375: 613-614, 2010.
-
(2010)
Lancet
, vol.375
, pp. 613-614
-
-
Escudier, B.1
-
4
-
-
33847644982
-
The novel functions of cGMP-specific phosphodiesterase 5 and its inhibitors in carcinoma cells and pulmonary/cardiovascular vessels
-
Zhu B and Strada SJ: The novel functions of cGMP-specific phosphodiesterase 5 and its inhibitors in carcinoma cells and pulmonary/cardiovascular vessels. Curr Top Med Chem 7: 437-454, 2007.
-
(2007)
Curr Top Med Chem
, vol.7
, pp. 437-454
-
-
Zhu, B.1
Strada, S.J.2
-
5
-
-
0034234978
-
Exisulind induction of apoptosis involves guanosine 3',5'-cyclic monophosphate phosphodiesterase inhibition, protein kinase G activation, and attenuated beta-catenin
-
Thompson WJ, Piazza GA, Li H, et al: Exisulind induction of apoptosis involves guanosine 3',5'-cyclic monophosphate phosphodiesterase inhibition, protein kinase G activation, and attenuated beta-catenin. Cancer Res 60: 3338-3342, 2000.
-
(2000)
Cancer Res
, vol.60
, pp. 3338-3342
-
-
Thompson, W.J.1
Piazza, G.A.2
Li, H.3
-
6
-
-
0035872448
-
Exisulind, a novel proapoptotic drug, inhibits rat urinary bladder tumorigenesis
-
Piazza GA, Thompson WJ, Pamukcu R, et al: Exisulind, a novel proapoptotic drug, inhibits rat urinary bladder tumorigenesis. Cancer Res 61: 3961-3968, 2001.
-
(2001)
Cancer Res
, vol.61
, pp. 3961-3968
-
-
Piazza, G.A.1
Thompson, W.J.2
Pamukcu, R.3
-
7
-
-
18444366205
-
Suppression of cyclic GMP-specific phosphodiesterase 5 promotes apoptosis and inhibits growth in HT29 cells
-
Zhu B, Vemavarapu L, Thompson WJ and Strada SJ: Suppression of cyclic GMP-specific phosphodiesterase 5 promotes apoptosis and inhibits growth in HT29 cells. J Cell Biochem 94: 336-350, 2005.
-
(2005)
J Cell Biochem
, vol.94
, pp. 336-350
-
-
Zhu, B.1
Vemavarapu, L.2
Thompson, W.J.3
Strada, S.J.4
-
8
-
-
0033213814
-
Sulindac derivatives inhibit growth and induce apoptosis in human prostate cancer cell lines
-
Lim JT, Piazza GA, Han EK, et al: Sulindac derivatives inhibit growth and induce apoptosis in human prostate cancer cell lines. Biochem Pharmacol 58: 1097-1107, 1999.
-
(1999)
Biochem Pharmacol
, vol.58
, pp. 1097-1107
-
-
Lim, J.T.1
Piazza, G.A.2
Han, E.K.3
-
9
-
-
73149104650
-
Sulindac sulfide selectively inhibits growth and induces apoptosis of human breast tumor cells by phosphodiesterase 5 inhibition, elevation of cyclic GMP, and activation of protein kinase G
-
Tinsley HN, Gary BD, Keeton AB, et al: Sulindac sulfide selectively inhibits growth and induces apoptosis of human breast tumor cells by phosphodiesterase 5 inhibition, elevation of cyclic GMP, and activation of protein kinase G. Mol Cancer Ther 8: 3331-3340, 2009.
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 3331-3340
-
-
Tinsley, H.N.1
Gary, B.D.2
Keeton, A.B.3
-
10
-
-
80051525438
-
Inhibition of PDE5 by sulindac sulfide selectively induces apoptosis and attenuates oncogenic Wnt/beta-catenin-mediated transcription in human breast tumor cells
-
Tinsley HN, Gary BD, Keeton AB, et al: Inhibition of PDE5 by sulindac sulfide selectively induces apoptosis and attenuates oncogenic Wnt/beta-catenin-mediated transcription in human breast tumor cells. Cancer Prev Res (Phila) 4: 1275-1284, 2011.
-
(2011)
Cancer Prev Res (Phila)
, vol.4
, pp. 1275-1284
-
-
Tinsley, H.N.1
Gary, B.D.2
Keeton, A.B.3
-
11
-
-
0033119801
-
Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells
-
Tetsu O and McCormick F: Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 398: 422-426, 1999.
-
(1999)
Nature
, vol.398
, pp. 422-426
-
-
Tetsu, O.1
McCormick, F.2
-
12
-
-
0036830654
-
Pro-apoptotic actions of exisulind and CP461 in SW480 colon tumor cells involve beta-catenin and cyclin D1 downregulation
-
Li H, Liu L, David ML, et al: Pro-apoptotic actions of exisulind and CP461 in SW480 colon tumor cells involve beta-catenin and cyclin D1 downregulation. Biochem Pharmacol 64: 1325-1336, 2002.
-
(2002)
Biochem Pharmacol
, vol.64
, pp. 1325-1336
-
-
Li, H.1
Liu, L.2
David, M.L.3
-
13
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
-
Livak KJ and Schmittgen TD: Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25: 402-408, 2001.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
14
-
-
2542619027
-
Activation of protein kinase G is sufficient to induce apoptosis and inhibit cell migration in colon cancer cells
-
Deguchi A, Thompson WJ and Weinstein IB: Activation of protein kinase G is sufficient to induce apoptosis and inhibit cell migration in colon cancer cells. Cancer Res 64: 3966-3973, 2004.
-
(2004)
Cancer Res
, vol.64
, pp. 3966-3973
-
-
Deguchi, A.1
Thompson, W.J.2
Weinstein, I.B.3
-
15
-
-
0033568521
-
Downregulation of cyclin D1 by transcriptional repression in MCF-7 human breast carcinoma cells induced by flavopiridol
-
Carlson B, Lahusen T, Singh S, et al: Downregulation of cyclin D1 by transcriptional repression in MCF-7 human breast carcinoma cells induced by flavopiridol. Cancer Res 59: 4634-4641, 1999.
-
(1999)
Cancer Res
, vol.59
, pp. 4634-4641
-
-
Carlson, B.1
Lahusen, T.2
Singh, S.3
-
16
-
-
0034757918
-
Cyclic GMP-dependent protein kinase activation and induction by exisulind and CP461 in colon tumor cells
-
Liu L, Li H, Underwood T, et al: Cyclic GMP-dependent protein kinase activation and induction by exisulind and CP461 in colon tumor cells. J Pharmacol Exp Ther 299: 583-592, 2001.
-
(2001)
J Pharmacol Exp Ther
, vol.299
, pp. 583-592
-
-
Liu, L.1
Li, H.2
Underwood, T.3
-
17
-
-
77953480176
-
PKG inhibits TCF signaling in colon cancer cells by blocking beta-catenin expression and activating FOXO4
-
Kwon IK, Wang R, Thangaraju M, et al: PKG inhibits TCF signaling in colon cancer cells by blocking beta-catenin expression and activating FOXO4. Oncogene 29: 3423-3434, 2010.
-
(2010)
Oncogene
, vol.29
, pp. 3423-3434
-
-
Kwon, I.K.1
Wang, R.2
Thangaraju, M.3
-
18
-
-
0033755261
-
Cyclic GMP mediates apoptosis induced by sulindac derivatives via activation of c-Jun NH2-terminal kinase 1
-
Soh JW, Mao Y, Kim MG, et al: Cyclic GMP mediates apoptosis induced by sulindac derivatives via activation of c-Jun NH2-terminal kinase 1. Clin Cancer Res 6: 4136-4141, 2000.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 4136-4141
-
-
Soh, J.W.1
Mao, Y.2
Kim, M.G.3
-
19
-
-
12844256402
-
The biology of cyclic GMP-dependent protein kinases
-
Hofmann F: The biology of cyclic GMP-dependent protein kinases. J Biol Chem 280: 1-4, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 1-4
-
-
Hofmann, F.1
-
20
-
-
57649155045
-
Protein kinase G-dependent cardioprotective mechanism of phosphodiesterase-5 inhibition involves phosphorylation of ERK and GSK3beta
-
Das A, Xi L and Kukreja RC: Protein kinase G-dependent cardioprotective mechanism of phosphodiesterase-5 inhibition involves phosphorylation of ERK and GSK3beta. J Biol Chem 283: 29572-29585, 2008.
-
(2008)
J Biol Chem
, vol.283
, pp. 29572-29585
-
-
Das, A.1
Xi, L.2
Kukreja, R.C.3
-
21
-
-
33845673263
-
Beta-catenin signaling: Linking renal cell carcinoma and polycystic kidney disease
-
Peruzzi B and Bottaro DP: Beta-catenin signaling: linking renal cell carcinoma and polycystic kidney disease. Cell Cycle 5: 2839-2841, 2006.
-
(2006)
Cell Cycle
, vol.5
, pp. 2839-2841
-
-
Peruzzi, B.1
Bottaro, D.P.2
-
22
-
-
34248674146
-
WNT/beta-catenin signaling in liver health and disease
-
Thompson MD and Monga SP: WNT/beta-catenin signaling in liver health and disease. Hepatology 45: 1298-1305, 2007.
-
(2007)
Hepatology
, vol.45
, pp. 1298-1305
-
-
Thompson, M.D.1
Monga, S.P.2
-
23
-
-
0347087570
-
Beta-catenin signaling in prostate cancer: An early perspective
-
Chesire DR and Isaacs WB: Beta-catenin signaling in prostate cancer: An early perspective. Endocr Relat Cancer 10: 537-560, 2003.
-
(2003)
Endocr Relat Cancer
, vol.10
, pp. 537-560
-
-
Chesire, D.R.1
Isaacs, W.B.2
-
24
-
-
79951502992
-
Intervening in beta-catenin signaling by sulindac inhibits S100A4-dependent colon cancer metastasis
-
Stein U, Arlt F, Smith J, et al: Intervening in beta-catenin signaling by sulindac inhibits S100A4-dependent colon cancer metastasis. Neoplasia 13: 131-144, 2011.
-
(2011)
Neoplasia
, vol.13
, pp. 131-144
-
-
Stein, U.1
Arlt, F.2
Smith, J.3
-
25
-
-
0038243190
-
Beta-Catenin signaling: Therapeutic strategies in oncology
-
Li H, Pamukcu R and Thompson WJ: beta-Catenin signaling: therapeutic strategies in oncology. Cancer Biol Ther 1: 621-625, 2002.
-
(2002)
Cancer Biol Ther
, vol.1
, pp. 621-625
-
-
Li, H.1
Pamukcu, R.2
Thompson, W.J.3
-
26
-
-
0035816261
-
Mutations of the beta-and gamma-catenin genes are uncommon in human lung, breast, kidney, cervical and ovarian carcinomas
-
Ueda M, Gemmill RM, West J, et al: Mutations of the beta-and gamma-catenin genes are uncommon in human lung, breast, kidney, cervical and ovarian carcinomas. Br J Cancer 85: 64-68, 2001.
-
(2001)
Br J Cancer
, vol.85
, pp. 64-68
-
-
Ueda, M.1
Gemmill, R.M.2
West, J.3
-
27
-
-
0028979727
-
Adenomatous polyposis coli gene mutations in ulcerative colitis-associated dysplasias and cancers versus sporadic colon neoplasms
-
Tarmin L, Yin J, Harpaz N, et al: Adenomatous polyposis coli gene mutations in ulcerative colitis-associated dysplasias and cancers versus sporadic colon neoplasms. Cancer Res 55: 2035-2038, 1995.
-
(1995)
Cancer Res
, vol.55
, pp. 2035-2038
-
-
Tarmin, L.1
Yin, J.2
Harpaz, N.3
-
28
-
-
82755192942
-
The C-terminus of Apc does not influence intestinal adenoma development or progression
-
Lewis A, Davis H, Deheragoda M, et al: The C-terminus of Apc does not influence intestinal adenoma development or progression. J Pathol 226: 73-83, 2012.
-
(2012)
J Pathol
, vol.226
, pp. 73-83
-
-
Lewis, A.1
Davis, H.2
Deheragoda, M.3
-
29
-
-
0142158595
-
Exisulind-induced apoptosis in a non-small cell lung cancer orthotopic lung tumor model augments docetaxel treatment and contributes to increased survival
-
Whitehead CM, Earle KA, Fetter J, et al: Exisulind-induced apoptosis in a non-small cell lung cancer orthotopic lung tumor model augments docetaxel treatment and contributes to increased survival. Mol Cancer Ther 2: 479-488, 2003.
-
(2003)
Mol Cancer Ther
, vol.2
, pp. 479-488
-
-
Whitehead, C.M.1
Earle, K.A.2
Fetter, J.3
-
30
-
-
0034759543
-
Cyclin D1 antisense oligonucleotide inhibits cell growth stimulated by epidermal growth factor and induces apoptosis of gastric cancer cells
-
Saikawa Y, Kubota T, Otani Y, et al: Cyclin D1 antisense oligonucleotide inhibits cell growth stimulated by epidermal growth factor and induces apoptosis of gastric cancer cells. Jpn J Cancer Res 92: 1102-1109, 2001.
-
(2001)
Jpn J Cancer Res
, vol.92
, pp. 1102-1109
-
-
Saikawa, Y.1
Kubota, T.2
Otani, Y.3
|