Interactions of nucleolin and ribosomal protein L26 (RPL26) in translational control of human p53 mRNA

Journal of Biological Chemistry

Volumn 287, Issue 20, 2012, Pages 16467-16476

  Chen, Jing ^a,b   Guo, Kexiao ^a   Kastan, Michael B ^a  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BASE PAIRING; DNA DAMAGES; DOUBLE-STRANDED RNA; HOMODIMERS; INTERACTION REGION; NUCLEOLIN; POINT MUTATIONS; RIBOSOMAL PROTEINS; RNA-BINDING DOMAINS; STRESS INDUCTION;

DIMERIZATION; GENES; OLIGOMERS; RNA;

DNA;

DOUBLE STRANDED RNA; MESSENGER RNA; NUCLEOLIN; PROTEIN P53; RIBOSOMAL PROTEIN L26; RIBOSOME PROTEIN; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; 5' UNTRANSLATED REGION; ARTICLE; BASE PAIRING; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; DIMERIZATION; DNA DAMAGE; HUMAN; HUMAN CELL; OLIGOMERIZATION; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DEFECT; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN RNA BINDING; RNA STABILITY; RNA STRUCTURE; RNA TRANSLATION; TRANSLATION REGULATION;

3' UNTRANSLATED REGIONS; CELL LINE, TUMOR; DNA DAMAGE; HUMANS; MODELS, BIOLOGICAL; PHOSPHOPROTEINS; POINT MUTATION; PROTEIN BIOSYNTHESIS; PROTEIN MULTIMERIZATION; RIBOSOMAL PROTEINS; RNA, DOUBLE-STRANDED; RNA-BINDING PROTEINS; STRESS, PHYSIOLOGICAL; TUMOR SUPPRESSOR PROTEIN P53;

PANTOLABUS;

EID: 84860857365     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.349274     Document Type: Article

References (30)

1. Takagi, M., Absalon, M. J., McLure, K. G., and Kastan, M. B. (2005) Regulation of p53 translation and induction after DNA damage by ribosomal protein L26 and nucleolin. Cell 123, 49-63 (Pubitemid 41414528)
2. Chen, J., and Kastan, M. B. (2010) 5′-3′-UTR interactions regulate p53 mRNAtranslation and provide a target for modulating p53 induction after DNA damage. Genes Dev. 24, 2146-2156
3. Kastan, M. B., and Bartek, J. (2004) Cell cycle checkpoints and cancer. Nature 432, 316-323
4. Levine, A. J., and Oren, M. (2009) The first 30 years of p53: growing ever more complex. Nat. Rev. Cancer 9, 749-758
5. Ashcroft, M., and Vousden, K. H. (1999) Regulation of p53 stability. Oncogene 18, 7637-7643 (Pubitemid 30052690)
6. Wade, M., Wang, Y. V., and Wahl, G. M. (2010) The p53 orchestra:Mdm2 and Mdmx set the tone. Trends Cell Biol. 20, 299-309
7. Mosner, J., Mummenbrauer, T., Bauer, C., Sczakiel, G., Grosse, F., and Deppert, W. (1995) Negative feedback regulation of wild-type p53 biosynthesis. EMBO J. 14, 4442-4449
8. Fu, L., and Benchimol, S. (1997) Participation of the human p53 3′-UTR in translational repression and activation following γ-irradiation. EMBO J. 16, 4117-4125 (Pubitemid 27281026)
9. Mazan-Mamczarz, K., Galbán, S., López de Silanes, I., Martindale, J. L., Atasoy, U., Keene, J. D., and Gorospe, M. (2003) RNA-binding protein HuR enhances p53 translation in response to ultraviolet light irradiation. Proc. Natl. Acad. Sci. U.S.A. 100, 8354-8359 (Pubitemid 36842549)
10. Schumacher, B., Hanazawa, M., Lee, M. H., Nayak, S., Volkmann, K., Hofmann, E. R., Hofmann, R., Hengartner, M., Schedl, T., and Gartner, A. (2005) Translational repression of C. elegans p53 by GLD-1 regulates DNA damage-induced apoptosis. Cell 120, 357-368 (Pubitemid 40222430)
11. Ofir-Rosenfeld, Y., Boggs, K., Michael, D., Kastan, M. B., and Oren, M. (2008) Mdm2 regulates p53 mRNA translation through inhibitory interactions with ribosomal protein L26. Mol. Cell 32, 180-189
12. Ginisty, H., Sicard, H., Roger, B., and Bouvet, P. (1999) Structure and functions of nucleolin. J. Cell Sci. 112, 761-772 (Pubitemid 29179310)
13. Mongelard, F., and Bouvet, P. (2007) Nucleolin: a multiFACeTed protein. Trends Cell Biol. 17, 80-86 (Pubitemid 46199181)
14. Bouvet, P., Allain, F. H., Finger, L. D., Dieckmann, T., and Feigon, J. (2001) Recognition of preformed and flexible elements of an RNA stem-loop by nucleolin. J. Mol. Biol. 309, 763-775 (Pubitemid 32595107)
15. Hall, K. B. (2002) RNA-protein interactions. Curr. Opin. Struct. Biol. 12, 283-288
16. Yang, C., Maiguel, D. A., and Carrier, F. (2002) Identification of nucleolin and nucleophosmin as genotoxic stress-responsive RNA-binding proteins. Nucleic Acids Res. 30, 2251-2260 (Pubitemid 34567946)
17. L messenger RNA in response to UVA irradiation. Cancer Res. 68, 1046-1054
18. Zhang, Y., Bhatia, D., Xia, H., Castranova, V., Shi, X., and Chen, F. (2006) Nucleolin links to arsenic-induced stabilization of GADD45α mRNA. Nucleic Acids Res. 34, 485-495 (Pubitemid 43245430)
19. Fähling, M., Mrowka, R., Steege, A., Nebrich, G., Perlewitz, A., Persson, P. B., and Thiele, B. J. (2006) Translational control of collagen prolyl 4-hydroxylase- α(I) gene expression under hypoxia. J. Biol. Chem. 281, 26089-26101 (Pubitemid 44401815)
20. Allain, F. H., Bouvet, P., Dieckmann, T., and Feigon, J. (2000) Molecular basis of sequence-specific recognition of pre-ribosomal RNA by nucleolin. EMBO J. 19, 6870-6881 (Pubitemid 32011680)
21. Bouvet, P., Jain, C., Belasco, J. G., Amalric, F., and Erard, M. (1997) RNA recognition by the joint action of two nucleolin RNA-binding domains: genetic analysis and structural modeling. EMBO J. 16, 5235-5246 (Pubitemid 27380132)
22. Dickinson, L. A., and Kohwi-Shigematsu, T. (1995) Nucleolin is a matrix attachment region DNA-binding protein that specifically recognizes a region with high base-unpairing potential. Mol. Cell. Biol. 15, 456-465 (Pubitemid 24379944)
23. Thyagarajan, B., Lundberg, R., Rafferty, M., and Campbell, C. (1998) Nucleolin promotes homologous DNA pairing in vitro. Somat. Cell Mol. Genet. 24, 263-272
24. Hanakahi, L. A., Bu, Z., and Maizels, N. (2000) The C-terminal domain of nucleolin accelerates nucleic acid annealing. Biochemistry 39, 15493-15499 (Pubitemid 32002776)
25. Yanagida, M., Shimamoto, A., Nishikawa, K., Furuichi, Y., Isobe, T., and Takahashi, N. (2001) Isolation and proteomic characterization of the major proteins of the nucleolin-binding ribonucleoprotein complexes. Proteomics 1, 1390-1404 (Pubitemid 33587895)
26. Kishore, S., Luber, S., and Zavolan, M. (2010) Deciphering the role of RNA-binding proteins in the post-transcriptional control of gene expression. Brief. Funct. Genomics 9, 391-404
27. Westphal, C. H., Hoyes, K. P., Canman, C. E., Huang, X., Kastan, M. B., Hendry, J. H., and Leder, P. (1998) Loss of atm radiosensitizes multiple p53 null tissues. Cancer Res. 58, 5637-5639 (Pubitemid 29006395)
28. Morelli, X., Bourgeas, R., and Roche, P. (2011) Chemical and structural lessons from recent successes in protein-protein interaction inhibition (2P2I). Curr. Opin. Chem. Biol. 15, 475-481
29. Mori, M., Manetti, F., and Botta, M. (2011) Targeting protein-protein and protein-nucleic acid interactions for anti-HIV therapy. Curr. Pharm. Des. 17, 3713-3728
30. Canman, C. E., Lim, D.-S., Cimprich, K. A., Taya, Y., Tamai, K., Sakaguchi, K., Appella, E., Kastan, M. B., and Siliciano, J. D. (1998) Activation of the ATM kinase by ionizing radiation and phosphorylation of p53. Science 281, 1677-1679 (Pubitemid 28435584)