-
1
-
-
79955082538
-
Apoptosis is an innate defense function of macrophages against Mycobacterium tuberculosis
-
S.M. Behar, C.J. Martin, M.G. Booty, T. Nishimura, X. Zhao, H.X. Gan, M. Divangahi, and H.G. Remold Apoptosis is an innate defense function of macrophages against Mycobacterium tuberculosis Mucosal Immunol. 4 2011 279 287
-
(2011)
Mucosal Immunol.
, vol.4
, pp. 279-287
-
-
Behar, S.M.1
Martin, C.J.2
Booty, M.G.3
Nishimura, T.4
Zhao, X.5
Gan, H.X.6
Divangahi, M.7
Remold, H.G.8
-
2
-
-
0035282782
-
Regulation of mitochondrial respiration by nitric oxide inhibition of cytochrome C oxidase
-
G.C. Brown Regulation of mitochondrial respiration by nitric oxide inhibition of cytochrome C oxidase Biochim. Biophys. Acta 1504 2001 46 57
-
(2001)
Biochim. Biophys. Acta
, vol.1504
, pp. 46-57
-
-
Brown, G.C.1
-
3
-
-
84869217908
-
Autophagy protects against active tuberculosis by suppressing bacterial burden and inflammation
-
E.F. Castillo, A. Dekonenko, J. Arko-Mensah, M.A. Mandell, N. Dupont, S. Jiang, M. Delgado-Vargas, G.S. Timmins, D. Bhattacharya, H. Yang, J. Hutt, C.R. Lyons, K.M. Dobos, and V. Deretic Autophagy protects against active tuberculosis by suppressing bacterial burden and inflammation Proc. Natl. Acad. Sci. U. S. A. 109 2012 E3168 E3176
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, pp. E3168-E3176
-
-
Castillo, E.F.1
Dekonenko, A.2
Arko-Mensah, J.3
Mandell, M.A.4
Dupont, N.5
Jiang, S.6
Delgado-Vargas, M.7
Timmins, G.S.8
Bhattacharya, D.9
Yang, H.10
Hutt, J.11
Lyons, C.R.12
Dobos, K.M.13
Deretic, V.14
-
4
-
-
77956508417
-
Autophagy facilitates IFN-gamma-induced Jak2-STAT1 activation and cellular inflammation
-
Y.P. Chang, C.C. Tsai, W.C. Huang, C.Y. Wang, C.L. Chen, Y.S. Lin, J.I. Kai, C.Y. Hsieh, Y.L. Cheng, P.C. Choi, S.H. Chen, S.P. Chang, H.S. Liu, and C.F. Lin Autophagy facilitates IFN-gamma-induced Jak2-STAT1 activation and cellular inflammation J. Biol. Chem. 285 2010 28715 28722
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 28715-28722
-
-
Chang, Y.P.1
Tsai, C.C.2
Huang, W.C.3
Wang, C.Y.4
Chen, C.L.5
Lin, Y.S.6
Kai, J.I.7
Hsieh, C.Y.8
Cheng, Y.L.9
Choi, P.C.10
Chen, S.H.11
Chang, S.P.12
Liu, H.S.13
Lin, C.F.14
-
5
-
-
84909578049
-
mTOR- and HIF-1alpha-mediated aerobic glycolysis as metabolic basis for trained immunity
-
S.C. Cheng, J. Quintin, R.A. Cramer, K.M. Shepardson, S. Saeed, V. Kumar, E.J. Giamarellos-Bourboulis, J.H. Martens, N.A. Rao, A. Aghajanirefah, G.R. Manjeri, Y. Li, D.C. Ifrim, R.J. Arts, B.M. van der Veer, P.M. Deen, C. Logie, L.A. O'Neill, P. Willems, F.L. van de Veerdonk, J.W. van der Meer, A. Ng, L.A. Joosten, C. Wijmenga, H.G. Stunnenberg, R.J. Xavier, and M.G. Netea mTOR- and HIF-1alpha-mediated aerobic glycolysis as metabolic basis for trained immunity Science 345 2014 1250684
-
(2014)
Science
, vol.345
, pp. 1250684
-
-
Cheng, S.C.1
Quintin, J.2
Cramer, R.A.3
Shepardson, K.M.4
Saeed, S.5
Kumar, V.6
Giamarellos-Bourboulis, E.J.7
Martens, J.H.8
Rao, N.A.9
Aghajanirefah, A.10
Manjeri, G.R.11
Li, Y.12
Ifrim, D.C.13
Arts, R.J.14
Van Der Veer, B.M.15
Deen, P.M.16
Logie, C.17
O'Neill, L.A.18
Willems, P.19
Van De Veerdonk, F.L.20
Van Der Meer, J.W.21
Ng, A.22
Joosten, L.A.23
Wijmenga, C.24
Stunnenberg, H.G.25
Xavier, R.J.26
Netea, M.G.27
more..
-
6
-
-
76349090912
-
The IKK complex contributes to the induction of autophagy
-
A. Criollo, L. Senovilla, H. Authier, M.C. Maiuri, E. Morselli, I. Vitale, O. Kepp, E. Tasdemir, L. Galluzzi, S. Shen, M. Tailler, N. Delahaye, A. Tesniere, D. De Stefano, A.B. Younes, F. Harper, G. Pierron, S. Lavandero, L. Zitvogel, A. Israel, V. Baud, and G. Kroemer The IKK complex contributes to the induction of autophagy EMBO J. 29 2009 619 631
-
(2009)
EMBO J.
, vol.29
, pp. 619-631
-
-
Criollo, A.1
Senovilla, L.2
Authier, H.3
Maiuri, M.C.4
Morselli, E.5
Vitale, I.6
Kepp, O.7
Tasdemir, E.8
Galluzzi, L.9
Shen, S.10
Tailler, M.11
Delahaye, N.12
Tesniere, A.13
De Stefano, D.14
Younes, A.B.15
Harper, F.16
Pierron, G.17
Lavandero, S.18
Zitvogel, L.19
Israel, A.20
Baud, V.21
Kroemer, G.22
more..
-
7
-
-
42249102086
-
Identification of RIP1 kinase as a specific cellular target of necrostatins
-
A. Degterev, J. Hitomi, M. Germscheid, I.L. Ch'en, O. Korkina, X. Teng, D. Abbott, G.D. Cuny, C. Yuan, G. Wagner, S.M. Hedrick, S.A. Gerber, A. Lugovskoy, and J. Yuan Identification of RIP1 kinase as a specific cellular target of necrostatins Nat. Chem. Biol. 4 2008 313 321
-
(2008)
Nat. Chem. Biol.
, vol.4
, pp. 313-321
-
-
Degterev, A.1
Hitomi, J.2
Germscheid, M.3
Ch'en, I.L.4
Korkina, O.5
Teng, X.6
Abbott, D.7
Cuny, G.D.8
Yuan, C.9
Wagner, G.10
Hedrick, S.M.11
Gerber, S.A.12
Lugovskoy, A.13
Yuan, J.14
-
8
-
-
79951910694
-
Autophagy in immunity and cell-autonomous defense against intracellular microbes
-
V. Deretic Autophagy in immunity and cell-autonomous defense against intracellular microbes Immunol. Rev. 240 2011 92 104
-
(2011)
Immunol. Rev.
, vol.240
, pp. 92-104
-
-
Deretic, V.1
-
9
-
-
84886797274
-
Autophagy in infection, inflammation and immunity
-
V. Deretic, T. Saitoh, and S. Akira Autophagy in infection, inflammation and immunity Nat. Rev. Immunol. 13 2013 722 737
-
(2013)
Nat. Rev. Immunol.
, vol.13
, pp. 722-737
-
-
Deretic, V.1
Saitoh, T.2
Akira, S.3
-
10
-
-
84865197492
-
Commitment to glycolysis sustains survival of NO-producing inflammatory dendritic cells
-
B. Everts, E. Amiel, G.J. van der Windt, T.C. Freitas, R. Chott, K.E. Yarasheski, E.L. Pearce, and E.J. Pearce Commitment to glycolysis sustains survival of NO-producing inflammatory dendritic cells Blood 120 2012 1422 1431
-
(2012)
Blood
, vol.120
, pp. 1422-1431
-
-
Everts, B.1
Amiel, E.2
Van Der Windt, G.J.3
Freitas, T.C.4
Chott, R.5
Yarasheski, K.E.6
Pearce, E.L.7
Pearce, E.J.8
-
11
-
-
0037097863
-
Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E
-
D.C. Fingar, S. Salama, C. Tsou, E. Harlow, and J. Blenis Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E Genes Dev. 16 2002 1472 1487
-
(2002)
Genes Dev.
, vol.16
, pp. 1472-1487
-
-
Fingar, D.C.1
Salama, S.2
Tsou, C.3
Harlow, E.4
Blenis, J.5
-
12
-
-
0034983918
-
Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase
-
K. Gottlob, N. Majewski, S. Kennedy, E. Kandel, R.B. Robey, and N. Hay Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase Genes Dev. 15 2001 1406 1418
-
(2001)
Genes Dev.
, vol.15
, pp. 1406-1418
-
-
Gottlob, K.1
Majewski, N.2
Kennedy, S.3
Kandel, E.4
Robey, R.B.5
Hay, N.6
-
13
-
-
25444524850
-
AKT activates the mammalian target of rapamycin by regulating cellular ATP level and AMPK activity
-
A. Hahn-Windgassen, V. Nogueira, C.C. Chen, J.E. Skeen, N. Sonenberg, and N. Hay AKT activates the mammalian target of rapamycin by regulating cellular ATP level and AMPK activity J. Biol. Chem. 280 2005 32081 32089
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 32081-32089
-
-
Hahn-Windgassen, A.1
Nogueira, V.2
Chen, C.C.3
Skeen, J.E.4
Sonenberg, N.5
Hay, N.6
-
14
-
-
65949097067
-
flowCore: a bioconductor package for high throughput flow cytometry
-
F. Hahne, N. LeMeur, R.R. Brinkman, B. Ellis, P. Haaland, D. Sarkar, J. Spidlen, E. Strain, and R. Gentleman flowCore: a bioconductor package for high throughput flow cytometry BMC Bioinform. 10 2009 106
-
(2009)
BMC Bioinform.
, vol.10
, pp. 106
-
-
Hahne, F.1
LeMeur, N.2
Brinkman, R.R.3
Ellis, B.4
Haaland, P.5
Sarkar, D.6
Spidlen, J.7
Strain, E.8
Gentleman, R.9
-
15
-
-
84862016400
-
The sedoheptulose kinase CARKL directs macrophage polarization through control of glucose metabolism
-
A. Haschemi, P. Kosma, L. Gille, C.R. Evans, C.F. Burant, P. Starkl, B. Knapp, R. Haas, J.A. Schmid, C. Jandl, S. Amir, G. Lubec, J. Park, H. Esterbauer, M. Bilban, L. Brizuela, J.A. Pospisilik, L.E. Otterbein, and O. Wagner The sedoheptulose kinase CARKL directs macrophage polarization through control of glucose metabolism Cell Metab. 15 2012 813 826
-
(2012)
Cell Metab.
, vol.15
, pp. 813-826
-
-
Haschemi, A.1
Kosma, P.2
Gille, L.3
Evans, C.R.4
Burant, C.F.5
Starkl, P.6
Knapp, B.7
Haas, R.8
Schmid, J.A.9
Jandl, C.10
Amir, S.11
Lubec, G.12
Park, J.13
Esterbauer, H.14
Bilban, M.15
Brizuela, L.16
Pospisilik, J.A.17
Otterbein, L.E.18
Wagner, O.19
-
16
-
-
0034683568
-
Tor-mediated induction of autophagy via an Apg1 protein kinase complex
-
Y. Kamada, T. Funakoshi, T. Shintani, K. Nagano, M. Ohsumi, and Y. Ohsumi Tor-mediated induction of autophagy via an Apg1 protein kinase complex J. Cell Biol. 150 2000 1507 1513
-
(2000)
J. Cell Biol.
, vol.150
, pp. 1507-1513
-
-
Kamada, Y.1
Funakoshi, T.2
Shintani, T.3
Nagano, K.4
Ohsumi, M.5
Ohsumi, Y.6
-
17
-
-
77954735369
-
Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation
-
C.M. Krawczyk, T. Holowka, J. Sun, J. Blagih, E. Amiel, R.J. DeBerardinis, J.R. Cross, E. Jung, C.B. Thompson, R.G. Jones, and E.J. Pearce Toll-like receptor-induced changes in glycolytic metabolism regulate dendritic cell activation Blood 115 2010 4742 4749
-
(2010)
Blood
, vol.115
, pp. 4742-4749
-
-
Krawczyk, C.M.1
Holowka, T.2
Sun, J.3
Blagih, J.4
Amiel, E.5
Deberardinis, R.J.6
Cross, J.R.7
Jung, E.8
Thompson, C.B.9
Jones, R.G.10
Pearce, E.J.11
-
18
-
-
33845977959
-
Mitochondrial membrane permeabilization in cell death
-
G. Kroemer, L. Galluzzi, and C. Brenner Mitochondrial membrane permeabilization in cell death Physiol. Rev. 87 2007 99 163
-
(2007)
Physiol. Rev.
, vol.87
, pp. 99-163
-
-
Kroemer, G.1
Galluzzi, L.2
Brenner, C.3
-
20
-
-
84897556094
-
The M1 and M2 paradigm of macrophage activation: time for reassessment
-
F.O. Martinez, and S. Gordon The M1 and M2 paradigm of macrophage activation: time for reassessment F1000Prime Rep. 6 2014 13
-
(2014)
F1000Prime Rep.
, vol.6
, pp. 13
-
-
Martinez, F.O.1
Gordon, S.2
-
21
-
-
84863610034
-
IFN-gamma elicits macrophage autophagy via the p38 MAPK signaling pathway
-
T. Matsuzawa, B.H. Kim, A.R. Shenoy, S. Kamitani, M. Miyake, and J.D. Macmicking IFN-gamma elicits macrophage autophagy via the p38 MAPK signaling pathway J. Immunol. 189 2012 813 818
-
(2012)
J. Immunol.
, vol.189
, pp. 813-818
-
-
Matsuzawa, T.1
Kim, B.H.2
Shenoy, A.R.3
Kamitani, S.4
Miyake, M.5
Macmicking, J.D.6
-
22
-
-
84871458229
-
Glucose induces autophagy under starvation conditions by a p38 MAPK-dependent pathway
-
J.F. Moruno-Manchon, E. Perez-Jimenez, and E. Knecht Glucose induces autophagy under starvation conditions by a p38 MAPK-dependent pathway Biochem. J. 449 2013 497 506
-
(2013)
Biochem. J.
, vol.449
, pp. 497-506
-
-
Moruno-Manchon, J.F.1
Perez-Jimenez, E.2
Knecht, E.3
-
23
-
-
0037310024
-
The many faces of macrophage activation
-
D.M. Mosser The many faces of macrophage activation J. Leukoc. Biol. 73 2003 209 212
-
(2003)
J. Leukoc. Biol.
, vol.73
, pp. 209-212
-
-
Mosser, D.M.1
-
24
-
-
84872576236
-
Metabolism of inflammation limited by AMPK and pseudo-starvation
-
L.A. O'Neill, and D.G. Hardie Metabolism of inflammation limited by AMPK and pseudo-starvation Nature 493 2013 346 355
-
(2013)
Nature
, vol.493
, pp. 346-355
-
-
O'Neill, L.A.1
Hardie, D.G.2
-
26
-
-
84859448447
-
Autophagy links inflammasomes to atherosclerotic progression
-
B. Razani, C. Feng, T. Coleman, R. Emanuel, H. Wen, S. Hwang, J.P. Ting, H.W. Virgin, M.B. Kastan, and C.F. Semenkovich Autophagy links inflammasomes to atherosclerotic progression Cell Metab. 15 2012 534 544
-
(2012)
Cell Metab.
, vol.15
, pp. 534-544
-
-
Razani, B.1
Feng, C.2
Coleman, T.3
Emanuel, R.4
Wen, H.5
Hwang, S.6
Ting, J.P.7
Virgin, H.W.8
Kastan, M.B.9
Semenkovich, C.F.10
-
27
-
-
40749111960
-
Using flowViz to visualize flow cytometry data
-
D. Sarkar, N. Le Meur, and R. Gentleman Using flowViz to visualize flow cytometry data Bioinformatics 24 2008 878 879
-
(2008)
Bioinformatics
, vol.24
, pp. 878-879
-
-
Sarkar, D.1
Le Meur, N.2
Gentleman, R.3
-
28
-
-
79959886743
-
Complex inhibitory effects of nitric oxide on autophagy
-
S. Sarkar, V.I. Korolchuk, M. Renna, S. Imarisio, A. Fleming, A. Williams, M. Garcia-Arencibia, C. Rose, S. Luo, B.R. Underwood, G. Kroemer, C.J. O'Kane, and D.C. Rubinsztein Complex inhibitory effects of nitric oxide on autophagy Mol. Cell 43 2011 19 32
-
(2011)
Mol. Cell
, vol.43
, pp. 19-32
-
-
Sarkar, S.1
Korolchuk, V.I.2
Renna, M.3
Imarisio, S.4
Fleming, A.5
Williams, A.6
Garcia-Arencibia, M.7
Rose, C.8
Luo, S.9
Underwood, B.R.10
Kroemer, G.11
O'Kane, C.J.12
Rubinsztein, D.C.13
-
30
-
-
34548235495
-
LPS/IFNgamma-induced RAW 264.7 apoptosis is regulated by both nitric oxide-dependent and -independent pathways involving JNK and the Bcl-2 family
-
A.R. Seminara, P.P. Ruvolo, and F. Murad LPS/IFNgamma-induced RAW 264.7 apoptosis is regulated by both nitric oxide-dependent and -independent pathways involving JNK and the Bcl-2 family Cell Cycle 6 2007 1772 1778
-
(2007)
Cell Cycle
, vol.6
, pp. 1772-1778
-
-
Seminara, A.R.1
Ruvolo, P.P.2
Murad, F.3
-
31
-
-
33748506089
-
Human IRGM induces autophagy to eliminate intracellular mycobacteria
-
S.B. Singh, A.S. Davis, G.A. Taylor, and V. Deretic Human IRGM induces autophagy to eliminate intracellular mycobacteria Science 313 2006 1438 1441
-
(2006)
Science
, vol.313
, pp. 1438-1441
-
-
Singh, S.B.1
Davis, A.S.2
Taylor, G.A.3
Deretic, V.4
-
32
-
-
84864149296
-
Helminth infection impairs autophagy-mediated killing of bacterial enteropathogens by macrophages
-
C.W. Su, Y. Cao, M. Zhang, J. Kaplan, L. Su, Y. Fu, W.A. Walker, R. Xavier, B.J. Cherayil, and H.N. Shi Helminth infection impairs autophagy-mediated killing of bacterial enteropathogens by macrophages J. Immunol. 189 2012 1459 1466
-
(2012)
J. Immunol.
, vol.189
, pp. 1459-1466
-
-
Su, C.W.1
Cao, Y.2
Zhang, M.3
Kaplan, J.4
Su, L.5
Fu, Y.6
Walker, W.A.7
Xavier, R.8
Cherayil, B.J.9
Shi, H.N.10
-
33
-
-
62449110463
-
Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling
-
M.C. Tal, M. Sasai, H.K. Lee, B. Yordy, G.S. Shadel, and A. Iwasaki Absence of autophagy results in reactive oxygen species-dependent amplification of RLR signaling Proc. Natl. Acad. Sci. U. S. A. 106 2009 2770 2775
-
(2009)
Proc. Natl. Acad. Sci. U. S. A.
, vol.106
, pp. 2770-2775
-
-
Tal, M.C.1
Sasai, M.2
Lee, H.K.3
Yordy, B.4
Shadel, G.S.5
Iwasaki, A.6
-
34
-
-
84882430393
-
Interferon-induced RIP1/RIP3-mediated necrosis requires PKR and is licensed by FADD and caspases
-
R.J. Thapa, S. Nogusa, P. Chen, J.L. Maki, A. Lerro, M. Andrake, G.F. Rall, A. Degterev, and S. Balachandran Interferon-induced RIP1/RIP3-mediated necrosis requires PKR and is licensed by FADD and caspases Proc. Natl. Acad. Sci. U. S. A. 110 2013 E3109 E3118
-
(2013)
Proc. Natl. Acad. Sci. U. S. A.
, vol.110
, pp. E3109-E3118
-
-
Thapa, R.J.1
Nogusa, S.2
Chen, P.3
Maki, J.L.4
Lerro, A.5
Andrake, M.6
Rall, G.F.7
Degterev, A.8
Balachandran, S.9
-
35
-
-
33645789048
-
IFN-gamma enhances production of nitric oxide from macrophages via a mechanism that depends on nucleotide oligomerization domain-2
-
S. Totemeyer, M. Sheppard, A. Lloyd, D. Roper, C. Dowson, D. Underhill, P. Murray, D. Maskell, and C. Bryant IFN-gamma enhances production of nitric oxide from macrophages via a mechanism that depends on nucleotide oligomerization domain-2 J. Immunol. 176 2006 4804 4810
-
(2006)
J. Immunol.
, vol.176
, pp. 4804-4810
-
-
Totemeyer, S.1
Sheppard, M.2
Lloyd, A.3
Roper, D.4
Dowson, C.5
Underhill, D.6
Murray, P.7
Maskell, D.8
Bryant, C.9
-
36
-
-
84865220380
-
Extracellular M. tuberculosis DNA targets bacteria for autophagy by activating the host DNA-sensing pathway
-
R.O. Watson, P.S. Manzanillo, and J.S. Cox Extracellular M. tuberculosis DNA targets bacteria for autophagy by activating the host DNA-sensing pathway Cell 150 2012 803 815
-
(2012)
Cell
, vol.150
, pp. 803-815
-
-
Watson, R.O.1
Manzanillo, P.S.2
Cox, J.S.3
-
37
-
-
77649271201
-
Bone Marrow-Derived Macrophages (BMM): isolation and applications
-
J. Weischenfeldt, and B. Porse Bone Marrow-Derived Macrophages (BMM): isolation and applications CSH Protoc. 2008 10.1101/pdb.prot5080
-
(2008)
CSH Protoc.
-
-
Weischenfeldt, J.1
Porse, B.2
-
38
-
-
84879475204
-
Autophagy and mitophagy in cellular damage control
-
J. Zhang Autophagy and mitophagy in cellular damage control Redox Biol. 1 2013 19 23
-
(2013)
Redox Biol.
, vol.1
, pp. 19-23
-
-
Zhang, J.1
-
39
-
-
38549136572
-
Macrophage activation by endogenous danger signals
-
X. Zhang, and D.M. Mosser Macrophage activation by endogenous danger signals J. Pathol. 214 2008 161 178
-
(2008)
J. Pathol.
, vol.214
, pp. 161-178
-
-
Zhang, X.1
Mosser, D.M.2
-
40
-
-
78651393239
-
A role for mitochondria in NLRP3 inflammasome activation
-
R. Zhou, A.S. Yazdi, P. Menu, and J. Tschopp A role for mitochondria in NLRP3 inflammasome activation Nature 469 2011 221 225
-
(2011)
Nature
, vol.469
, pp. 221-225
-
-
Zhou, R.1
Yazdi, A.S.2
Menu, P.3
Tschopp, J.4
|