메뉴 건너뛰기




Volumn 287, Issue 10, 2012, Pages 7169-7181

Membrane estrogen signaling enhances tumorigenesis and metastatic potential of breast cancer cells via estrogen receptor-α36 (ERα36)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI-APOPTOTIC EFFECTS; BREAST CANCER; BREAST CANCER CELLS; CANCER CELLS; CELL VIABILITY; DELETERIOUS EFFECTS; DNA FRAGMENTATION; DOWNSTREAM EFFECTS; ESTROGEN RECEPTOR; IN-VITRO ASSAYS; INVASIVENESS; METASTATIC POTENTIAL; MULTIPLE CELLS; PRO-APOPTOTIC EFFECTS; PROTEIN KINASE C; QUANTITATIVE RT-PCR; SPLICE VARIANTS; TUMORIGENESIS; TUMORIGENICITY; WESTERN BLOTS;

EID: 84857756831     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.292946     Document Type: Article
Times cited : (92)

References (49)
  • 1
    • 44549085837 scopus 로고    scopus 로고
    • Membrane-initiated steroid action in breast and prostate cancer
    • Kampa, M., Pelekanou, V., and Castanas, E. (2008) Membrane-initiated steroid action in breast and prostate cancer. Steroids 73, 953-960
    • (2008) Steroids , vol.73 , pp. 953-960
    • Kampa, M.1    Pelekanou, V.2    Castanas, E.3
  • 2
    • 34748842643 scopus 로고    scopus 로고
    • Estrogen receptor DNA binding is not required for estrogen-induced breast cell growth
    • DOI 10.1016/j.mce.2007.07.006, PII S0303720707002602
    • DeNardo, D. G., Cuba, V. L., Kim, H., Wu, K., Lee, A. V., and Brown, P. H. (2007) Estrogen receptor DNA binding is not required for estrogen-induced breast cell growth. Mol. Cell. Endocrinol. 277, 13-25 (Pubitemid 47488609)
    • (2007) Molecular and Cellular Endocrinology , vol.277 , Issue.1-2 , pp. 13-25
    • DeNardo, D.G.1    Cuba, V.L.2    Kim, H.3    Wu, K.4    Lee, A.V.5    Brown, P.H.6
  • 4
    • 0029042672 scopus 로고
    • Recurrence-free survival in breast cancer improved by adjuvant tamoxifen. Especially for progesterone receptor-positive tumors with a high proliferation
    • Fernö, M., Baldetorp, B., Bendahl, P. O., Borg, A., Ewers, S. B., Olsson, H., Rydén, S., Sigurdsson, H., and Killander, D. (1995) Recurrence-free survival in breast cancer improved by adjuvant tamoxifen. Especially for progesterone receptor-positive tumors with a high proliferation. Breast Cancer Res. Treat. 36, 23-34
    • (1995) Breast Cancer Res. Treat. , vol.36 , pp. 23-34
    • Fernö, M.1    Baldetorp, B.2    Bendahl, P.O.3    Borg, A.4    Ewers, S.B.5    Olsson, H.6    Rydén, S.7    Sigurdsson, H.8    Killander, D.9
  • 5
    • 0028961127 scopus 로고
    • Differential expression of estrogen receptor mRNA splice variants in the tamoxifen-resistant human breast cancer cell line, MCF-7/TAMR-1 compared to the parental MCF-7 cell line
    • Madsen, M. W., Reiter, B. E., and Lykkesfeldt, A. E. (1995) Differential expression of estrogen receptor mRNA splice variants in the tamoxifen-resistant human breast cancer cell line, MCF-7/TAMR-1 compared to the parental MCF-7 cell line. Mol. Cell. Endocrinol. 109, 197-207
    • (1995) Mol. Cell. Endocrinol. , vol.109 , pp. 197-207
    • Madsen, M.W.1    Reiter, B.E.2    Lykkesfeldt, A.E.3
  • 6
    • 0034176556 scopus 로고    scopus 로고
    • Identification of twenty alternatively spliced estrogen receptor alpha mRNAs in breast cancer cell lines and tumors using splice targeted primer approach
    • DOI 10.1016/S0960-0760(00)00033-9, PII S0960076000000339
    • Poola, I., Koduri, S., Chatra, S., and Clarke, R. (2000) Identification of 20 alternatively spliced estrogen receptor α mRNAsin breast cancer cell lines and tumors using splice targeted primer approach. J. Steroid Biochem. Mol. Biol. 72, 249-258 (Pubitemid 30261529)
    • (2000) Journal of Steroid Biochemistry and Molecular Biology , vol.72 , Issue.5 , pp. 249-258
    • Poola, I.1    Koduri, S.2    Chatra, S.3    Clarke, R.4
  • 7
    • 0033230631 scopus 로고    scopus 로고
    • Cellular functions of the plasma membrane estrogen receptor
    • Levin, E. R. (1999) Cellular functions of the plasma membrane estrogen receptor. Trends Endocrinol. Metab. 10, 374-377
    • (1999) Trends Endocrinol. Metab. , vol.10 , pp. 374-377
    • Levin, E.R.1
  • 8
    • 0033623490 scopus 로고    scopus 로고
    • The membrane effects of 17β-estradiol on chondrocyte phenotypic expression are mediated by activation of protein kinase C through phospholipase C and G-proteins
    • Sylvia, V. L., Boyan, B. D., Dean, D. D., and Schwartz, Z. (2000) The membrane effects of 17β-estradiol on chondrocyte phenotypic expression are mediated by activation of protein kinase C through phospholipase C and G-proteins. J. Steroid. Biochem. Mol. Biol. 73, 211-224
    • (2000) J. Steroid. Biochem. Mol. Biol. , vol.73 , pp. 211-224
    • Sylvia, V.L.1    Boyan, B.D.2    Dean, D.D.3    Schwartz, Z.4
  • 9
    • 25144517216 scopus 로고    scopus 로고
    • Estrogen rapid action via protein complex formation involving ERα and Src
    • DOI 10.1016/j.tem.2005.06.010, PII S1043276005001840
    • Song, R. X., Zhang, Z., and Santen, R. J. (2005) Estrogen rapid action via protein complex formation involving ERα and Src. Trends Endocrinol. Metab. 16, 347-353 (Pubitemid 41338739)
    • (2005) Trends in Endocrinology and Metabolism , vol.16 , Issue.8 , pp. 347-353
    • Song, R.X.-D.1    Zhang, Z.2    Santen, R.J.3
  • 10
    • 67449141657 scopus 로고    scopus 로고
    • Membrane-initiated actions of estrogen on the endothelium
    • Kim, K. H., and Bender, J. R. (2009) Membrane-initiated actions of estrogen on the endothelium. Mol. Cell. Endocrinol. 308, 3-8
    • (2009) Mol. Cell. Endocrinol. , vol.308 , pp. 3-8
    • Kim, K.H.1    Bender, J.R.2
  • 11
    • 0036225488 scopus 로고    scopus 로고
    • Tamoxifen elicits its anti-estrogen effects in growth plate chondrocytes by inhibiting protein kinase C
    • DOI 10.1016/S0960-0760(02)00038-9, PII S0960076002000389
    • Schwartz, Z., Sylvia, V. L., Guinee, T., Dean, D. D., and Boyan, B. D. (2002) Tamoxifen elicits its anti-estrogen effects in growth plate chondrocytes by inhibiting protein kinase C. J. Steroid Biochem. Mol. Biol. 80, 401-410 (Pubitemid 34442602)
    • (2002) Journal of Steroid Biochemistry and Molecular Biology , vol.80 , Issue.4-5 , pp. 401-410
    • Schwartz, Z.1    Sylvia, V.L.2    Guinee, T.3    Dean, D.D.4    Boyan, B.D.5
  • 12
    • 33646533981 scopus 로고    scopus 로고
    • Sex-specific regulation of growth plate chondrocytes by estrogen is via multiple MAP kinase signaling pathways
    • McMillan, J., Fatehi-Sedeh, S., Sylvia, V. L., Bingham, V., Zhong, M., Boyan, B. D., and Schwartz, Z. (2006) Sex-specific regulation of growth plate chondrocytes by estrogen is via multiple MAP kinase signaling pathways. Biochim. Biophys. Acta 1763, 381-392
    • (2006) Biochim. Biophys. Acta , vol.1763 , pp. 381-392
    • McMillan, J.1    Fatehi-Sedeh, S.2    Sylvia, V.L.3    Bingham, V.4    Zhong, M.5    Boyan, B.D.6    Schwartz, Z.7
  • 13
    • 0037734126 scopus 로고    scopus 로고
    • Estrogen-dependent rapid activation of protein kinase C in estrogen receptor-positive MCF-7 breast cancer cells and estrogen receptor-negative HCC38 cells is membrane-mediated and inhibited by tamoxifen
    • DOI 10.1210/en.2002-221018
    • Boyan, B. D., Sylvia, V. L., Frambach, T., Lohmann, C. H., Dietl, J., Dean, D. D., and Schwartz, Z. (2003) Estrogen-dependent rapid activation of protein kinase C in estrogen receptor-positive MCF-7 breast cancer cells and estrogen receptor-negative HCC38 cells is membrane-mediated and inhibited by tamoxifen. Endocrinology 144, 1812-1824 (Pubitemid 36543319)
    • (2003) Endocrinology , vol.144 , Issue.5 , pp. 1812-1824
    • Boyan, B.D.1    Sylvia, V.L.2    Frambach, T.3    Lohmann, C.H.4    Dietl, J.5    Dean, D.D.6    Shwartz, Z.7
  • 14
    • 25644437706 scopus 로고    scopus 로고
    • Identification, cloning, and expression of human estrogen receptor-α36, a novel variant of human estrogen receptor-α66
    • DOI 10.1016/j.bbrc.2005.08.226, PII S0006291X05019510
    • Wang, Z., Zhang, X., Shen, P., Loggie, B. W., Chang, Y., and Deuel, T. F. (2005) Identification, cloning, and expression of human estrogen receptor- α36, a novel variant of human estrogen receptor-α66. Biochem. Biophys. Res. Commun. 336, 1023-1027 (Pubitemid 41383424)
    • (2005) Biochemical and Biophysical Research Communications , vol.336 , Issue.4 , pp. 1023-1027
    • Zhao, Y.W.1    Zhang, X.2    Shen, P.3    Loggie, B.W.4    Chang, Y.5    Deuel, T.F.6
  • 15
    • 70449513386 scopus 로고    scopus 로고
    • A novel variant of ER-α, ER-α36 mediates testosterone- stimulated ERK and Akt activation in endometrial cancer Hec1A cells
    • Lin, S. L., Yan, L. Y., Liang, X. W., Wang, Z. B., Wang, Z. Y., Qiao, J., Schatten, H., and Sun, Q. Y. (2009) A novel variant of ER-α, ER-α36 mediates testosterone-stimulated ERK and Akt activation in endometrial cancer Hec1A cells. Reprod. Biol. Endocrinol. 7, 102
    • (2009) Reprod. Biol. Endocrinol. , vol.7 , pp. 102
    • Lin, S.L.1    Yan, L.Y.2    Liang, X.W.3    Wang, Z.B.4    Wang, Z.Y.5    Qiao, J.6    Schatten, H.7    Sun, Q.Y.8
  • 17
    • 14844343093 scopus 로고    scopus 로고
    • A transmembrane intracellular estrogen receptor mediates rapid cell signaling
    • DOI 10.1126/science.1106943
    • Revankar, C. M., Cimino, D. F., Sklar, L. A., Arterburn, J. B., and Prossnitz, E. R. (2005) A transmembrane intracellular estrogen receptor mediates rapid cell signaling. Science 307, 1625-1630 (Pubitemid 40354745)
    • (2005) Science , vol.307 , Issue.5715 , pp. 1625-1630
    • Revankar, C.M.1    Cimino, D.F.2    Sklar, L.A.3    Arterburn, J.B.4    Prossnitz, E.R.5
  • 18
    • 77950407928 scopus 로고    scopus 로고
    • Involvement of estrogen receptor variant ER-α36, not GPR30, in nongenomic estrogen signaling
    • Kang, L., Zhang, X., Xie, Y., Tu, Y., Wang, D., Liu, Z., and Wang, Z. Y. (2010) Involvement of estrogen receptor variant ER-α36, not GPR30, in nongenomic estrogen signaling. Mol. Endocrinol. 24, 709-721
    • (2010) Mol. Endocrinol. , vol.24 , pp. 709-721
    • Kang, L.1    Zhang, X.2    Xie, Y.3    Tu, Y.4    Wang, D.5    Liu, Z.6    Wang, Z.Y.7
  • 19
    • 43749118434 scopus 로고    scopus 로고
    • Estrogen induces estrogen-related receptor α gene expression and chromatin structural changes in estrogen receptor (ER)-positive and ER-negative breast cancer cells
    • Hu, P., Kinyamu, H. K., Wang, L., Martin, J., Archer, T. K., and Teng, C. (2008) Estrogen induces estrogen-related receptor α gene expression and chromatin structural changes in estrogen receptor (ER)-positive and ER-negative breast cancer cells. J. Biol. Chem. 283, 6752-6763
    • (2008) J. Biol. Chem. , vol.283 , pp. 6752-6763
    • Hu, P.1    Kinyamu, H.K.2    Wang, L.3    Martin, J.4    Archer, T.K.5    Teng, C.6
  • 20
    • 0025302879 scopus 로고
    • Stable transfection of the estrogen receptor cDNA into Hela cells induces estrogen responsiveness of endogenous cathepsin D gene but not of cell growth
    • DOI 10.1016/0006-291X(90)91440-4
    • Touitou, I., Mathieu, M., and Rochefort, H. (1990) Stable transfection of the estrogen receptor cDNA into HeLa cells induces estrogen responsiveness of endogenous cathepsin D gene but not of cell growth. Biochem. Biophys. Res. Commun. 169, 109-115 (Pubitemid 20180999)
    • (1990) Biochemical and Biophysical Research Communications , vol.169 , Issue.1 , pp. 109-115
    • Touitou, I.1    Mathieu, M.2    Rochefort, H.3
  • 22
    • 0028820041 scopus 로고
    • A detergent-free method for purifying caveolae membrane from tissue culture cells
    • Smart, E. J., Ying, Y. S., Mineo, C., and Anderson, R. G. (1995)A detergent-free method for purifying caveolae membrane from tissue culture cells. Proc. Natl. Acad. Sci. U.S.A. 92, 10104-10108
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , pp. 10104-10108
    • Smart, E.J.1    Ying, Y.S.2    Mineo, C.3    Anderson, R.G.4
  • 25
    • 0033732896 scopus 로고    scopus 로고
    • Plasma membrane estrogen receptors signal to antiapoptosis in breast cancer
    • Razandi, M., Pedram, A., and Levin, E. R. (2000) Plasma membrane estrogen receptors signal to antiapoptosis in breast cancer. Mol. Endocrinol. 14, 1434-1447
    • (2000) Mol. Endocrinol. , vol.14 , pp. 1434-1447
    • Razandi, M.1    Pedram, A.2    Levin, E.R.3
  • 26
    • 34347233468 scopus 로고    scopus 로고
    • Estrogen receptor α mediates breast cancer cell resistance to paclitaxel through inhibition of apoptotic cell death
    • DOI 10.1158/0008-5472.CAN-06-4582
    • Sui, M., Huang, Y., Park, B. H., Davidson, N. E., and Fan, W. (2007) Estrogen receptor α mediates breast cancer cell resistance to paclitaxel through inhibition of apoptotic cell death. Cancer Res. 67, 5337-5344 (Pubitemid 46997273)
    • (2007) Cancer Research , vol.67 , Issue.11 , pp. 5337-5344
    • Sui, M.1    Huang, Y.2    Ben, H.P.3    Davidson, N.E.4    Fan, W.5
  • 27
    • 57449110197 scopus 로고    scopus 로고
    • Inhibition of phosphate-induced apoptosis in resting zone chondrocytes by thrombin peptide 508
    • Zhong, M., Carney, D. H., Ryaby, J. T., Schwartz, Z., and Boyan, B. D. (2009) Inhibition of phosphate-induced apoptosis in resting zone chondrocytes by thrombin peptide 508. Cells Tissues Organs 189, 56-59
    • (2009) Cells Tissues Organs , vol.189 , pp. 56-59
    • Zhong, M.1    Carney, D.H.2    Ryaby, J.T.3    Schwartz, Z.4    Boyan, B.D.5
  • 29
    • 33749071868 scopus 로고    scopus 로고
    • Breast cancer-derived factors facilitate osteolytic bone metastasis
    • Rose, A. A., and Siegel, P. M. (2006) Breast cancer-derived factors facilitate osteolytic bone metastasis. Bull. Cancer 93, 931-943 (Pubitemid 44520875)
    • (2006) Bulletin du Cancer , vol.93 , Issue.9 , pp. 931-943
    • Rose, A.A.N.1    Siegel, P.M.2
  • 30
    • 33846920297 scopus 로고    scopus 로고
    • FGF2 posttranscriptionally down-regulates expression of SDF1 in bone marrow stromal cells through FGFR1 IIIc
    • DOI 10.1182/blood-2006-06-028217
    • Nakayama, T., Mutsuga, N., and Tosato, G. (2007) FGF2 post-transcriptionally down-regulates expression of SDF1 in bone marrow stromal cells through FGFR1 IIIc. Blood 109, 1363-1372 (Pubitemid 46239566)
    • (2007) Blood , vol.109 , Issue.4 , pp. 1363-1372
    • Nakayama, T.1    Mutsuga, N.2    Tosato, G.3
  • 31
    • 51449094588 scopus 로고    scopus 로고
    • Estradiol-estrogen receptor. A key interplay of the expression of syndecan-2 and metalloproteinase- 9 in breast cancer cells
    • Kousidou, O. Ch., Berdiaki, A., Kletsas, D., Zafiropoulos, A., Theocharis, A. D., Tzanakakis, G. N., and Karamanos, N. K. (2008) Estradiol-estrogen receptor. A key interplay of the expression of syndecan-2 and metalloproteinase- 9 in breast cancer cells. Mol. Oncol. 2, 223-232
    • (2008) Mol. Oncol. , vol.2 , pp. 223-232
    • Kousidou, O.Ch.1    Berdiaki, A.2    Kletsas, D.3    Zafiropoulos, A.4    Theocharis, A.D.5    Tzanakakis, G.N.6    Karamanos, N.K.7
  • 32
    • 0242361764 scopus 로고    scopus 로고
    • Bisphosphonate induced growth inhibition of breast cancer cells is augmented by p38 inhibition
    • DOI 10.1023/A:1026126430905
    • Merrell, M., Suarez-Cuervo, C., Harris, K. W., Väänänen, H. K., and Selander, K. S. (2003) Bisphosphonate induced growth inhibition of breast cancer cells is augmented by p38 inhibition. Breast Cancer Res. Treat. 81, 231-241 (Pubitemid 37352460)
    • (2003) Breast Cancer Research and Treatment , vol.81 , Issue.3 , pp. 231-241
    • Merrell, M.1    Suarez-Cuervo, C.2    Harris, K.W.3    Vaananen, H.K.4    Selander, K.S.5
  • 33
    • 75449112004 scopus 로고    scopus 로고
    • Expression of estrogen receptor α with a Tet-Off adenoviral system induces G0/G1 cell cycle arrest in SKBr3 breast cancer cells
    • Peng, J., and Jordan, V. C. (2010) Expression of estrogen receptor α with a Tet-Off adenoviral system induces G0/G1 cell cycle arrest in SKBr3 breast cancer cells. Int. J. Oncol. 36, 451-458
    • (2010) Int. J. Oncol. , vol.36 , pp. 451-458
    • Peng, J.1    Jordan, V.C.2
  • 34
    • 34347238583 scopus 로고    scopus 로고
    • Activation of the novel estrogen receptor G protein-coupled receptor 30 (GPR30) at the plasma membrane
    • DOI 10.1210/en.2006-1605
    • Filardo, E., Quinn, J., Pang, Y., Graeber, C., Shaw, S., Dong, J., and Thomas, P. (2007) Activation of the novel estrogen receptor G protein-coupled receptor 30 (GPR30) at the plasma membrane. Endocrinology 148, 3236-3245 (Pubitemid 46997004)
    • (2007) Endocrinology , vol.148 , Issue.7 , pp. 3236-3245
    • Filardo, E.1    Quinn, J.2    Pang, Y.3    Graeber, C.4    Shaw, S.5    Dong, J.6    Thomas, P.7
  • 35
    • 78650834899 scopus 로고    scopus 로고
    • 17β-Estradiol regulates rat growth plate chondrocyte apoptosis through a mitochondrial pathway not involving nitric oxide or MAPKs
    • Zhong, M., Carney, D. H., Boyan, B. D., and Schwartz, Z. (2011) 17β-Estradiol regulates rat growth plate chondrocyte apoptosis through a mitochondrial pathway not involving nitric oxide or MAPKs. Endocrinology 152, 82-92
    • (2011) Endocrinology , vol.152 , pp. 82-92
    • Zhong, M.1    Carney, D.H.2    Boyan, B.D.3    Schwartz, Z.4
  • 37
    • 70349401677 scopus 로고    scopus 로고
    • GPR30/GPER1. Searching for a role in estrogen physiology
    • Olde, B., and Leeb-Lundberg, L. M. (2009) GPR30/GPER1. Searching for a role in estrogen physiology. Trends Endocrinol. Metab. 20, 409-416
    • (2009) Trends Endocrinol. Metab. , vol.20 , pp. 409-416
    • Olde, B.1    Leeb-Lundberg, L.M.2
  • 38
    • 77954762255 scopus 로고    scopus 로고
    • 2-vitamin D3-dependent modulation of Src, MAPK cascades and VDR localization in skeletal muscle cells
    • 2-vitamin D3-dependent modulation of Src, MAPK cascades and VDR localization in skeletal muscle cells. J. Steroid Biochem. Mol. Biol. 121, 169-175
    • (2010) J. Steroid Biochem. Mol. Biol. , vol.121 , pp. 169-175
    • Buitrago, C.1    Boland, R.2
  • 39
    • 0344549854 scopus 로고    scopus 로고
    • Nongenomic stimulation of nitric oxide release by estrogen is mediated by estrogen receptor α localized in caveolae
    • Kim, H. P., Lee, J. Y., Jeong, J. K., Bae, S. W., Lee, H. K., and Jo, I. (1999) Nongenomic stimulation of nitric oxide release by estrogen is mediated by estrogen receptor α localized in caveolae. Biochem. Biophys. Res. Commun. 263, 257-262
    • (1999) Biochem. Biophys. Res. Commun. , vol.263 , pp. 257-262
    • Kim, H.P.1    Lee, J.Y.2    Jeong, J.K.3    Bae, S.W.4    Lee, H.K.5    Jo, I.6
  • 40
    • 0034941591 scopus 로고    scopus 로고
    • β-estradiol stimulation of DNA synthesis requires different PKC isoforms in HEPG2 and MCF7 cells
    • DOI 10.1002/jcp.1105
    • Marino, M., Distefano, E., Caporali, S., Ceracchi, G., Pallottini, V., and Trentalance, A. (2001) β-Estradiol stimulation of DNA synthesis requires different PKC isoforms in HepG2 and MCF7 cells. J. Cell. Physiol. 188, 170-177 (Pubitemid 32622907)
    • (2001) Journal of Cellular Physiology , vol.188 , Issue.2 , pp. 170-177
    • Marino, M.1    Distefano, E.2    Caporali, S.3    Ceracchi, G.4    Pallottini, V.5    Trentalance, A.6
  • 41
    • 0033160367 scopus 로고    scopus 로고
    • Overexpression of protein kinase C-α in MCF-7 breast cancer cells results in differential regulation and expression of αvβ3 and αvβ5
    • Carey, I., Williams, C. L., Ways, D. K., and Noti, J. D. (1999) Overexpression of protein kinase C-α in MCF-7 breast cancer cells results in differential regulation and expression of αvβ3 and αvβ5. Int. J. Oncol. 15, 127-136
    • (1999) Int. J. Oncol. , vol.15 , pp. 127-136
    • Carey, I.1    Williams, C.L.2    Ways, D.K.3    Noti, J.D.4
  • 43
    • 33746114248 scopus 로고    scopus 로고
    • The crucial role of cyclooxygenase-2 in osteopontin-induced protein kinase C α/c-Src/IκB kinase α/β-dependent prostate tumor progression and angiogenesis
    • DOI 10.1158/0008-5472.CAN-06-0661
    • Jain, S., Chakraborty, G., and Kundu, G. C. (2006) The crucial role of cyclooxygenase-2 in osteopontin-induced protein kinase C α/c-Src/IκB kinase α/β-dependent prostate tumor progression and angiogenesis. Cancer Res. 66, 6638-6648 (Pubitemid 44085620)
    • (2006) Cancer Research , vol.66 , Issue.13 , pp. 6638-6648
    • Jain, S.1    Chakraborty, G.2    Kundu, G.C.3
  • 44
    • 0028903545 scopus 로고
    • MCF-7 breast cancer cells transfected with protein kinase C-α exhibit altered expression of other protein kinase C isoforms and display a more aggressive neoplastic phenotype
    • Ways, D. K., Kukoly, C. A., deVente, J., Hooker, J. L., Bryant, W. O., Posekany, K. J., Fletcher, D. J., Cook, P. P., and Parker, P. J. (1995) MCF-7 breast cancer cells transfected with protein kinase C-α exhibit altered expression of other protein kinase C isoforms and display a more aggressive neoplastic phenotype. J. Clin. Invest. 95, 1906-1915
    • (1995) J. Clin. Invest. , vol.95 , pp. 1906-1915
    • Ways, D.K.1    Kukoly, C.A.2    DeVente, J.3    Hooker, J.L.4    Bryant, W.O.5    Posekany, K.J.6    Fletcher, D.J.7    Cook, P.P.8    Parker, P.J.9
  • 45
    • 0031017630 scopus 로고    scopus 로고
    • Expression of the invasive phenotype by MCF-7 human breast cancer cells transfected to overexpress protein kinase C-α or the erbB2 proto-oncogene
    • Connolly, J., and Rose, D. (1997) Expression of the invasive phenotype by MCF-7 human breast cancer cells transfected to overexpress protein kinase C-α or the erbB2 proto-oncogene. Int. J. Oncol. 10, 71-76 (Pubitemid 26426657)
    • (1997) International Journal of Oncology , vol.10 , Issue.1 , pp. 71-76
    • Connolly, J.M.1    Rose, D.P.2
  • 48
    • 0038700554 scopus 로고    scopus 로고
    • Epithelia-mesenchymal transition in breast cancer development
    • DOI 10.1186/bcr578
    • Vincent-Salomon, A., and Thiery, J. P. (2003) Host microenvironment in breast cancer development. Epithelial-mesenchymal transition in breast cancer development. Breast Cancer Res. 5, 101-106 (Pubitemid 36348104)
    • (2003) Breast Cancer Research , vol.5 , Issue.2 , pp. 101-106
    • Vincent-Salomon, A.1    Thiery, J.P.2
  • 49
    • 77952979940 scopus 로고    scopus 로고
    • A variant of estrogen receptor-α, ER-α36 is expressed in human gastric cancer and is highly correlated with lymph node metastasis
    • Deng, H., Huang, X., Fan, J., Wang, L., Xia, Q., Yang, X., Wang, Z., and Liu, L. (2010) A variant of estrogen receptor-α, ER-α36 is expressed in human gastric cancer and is highly correlated with lymph node metastasis. Oncol. Rep. 24, 171-176
    • (2010) Oncol. Rep. , vol.24 , pp. 171-176
    • Deng, H.1    Huang, X.2    Fan, J.3    Wang, L.4    Xia, Q.5    Yang, X.6    Wang, Z.7    Liu, L.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.