Regulation of the extrinsic apoptotic pathway by microRNA-21 in alcoholic liver injury

Journal of Biological Chemistry

Volumn 289, Issue 40, 2014, Pages 27526-27539

  Francis, Heather ^a,b   McDaniel, Kelly ^a,b   Han, Yuyan ^b   Liu, Xiuping ^c   Kennedy, Lindsey ^a,b   Yang, Fuquan ^d   McCarra, Jennifer ^b   Zhou, Tianhao ^b   Glaser, Shannon ^a,b   Venter, Julie ^b   Huang, Li ^e   Levine, Phillip ^b   Lai, Jia Ming ^e   Liu, Chang Gong ^c   Alpini, Gianfranco ^a,b,f   Meng, Fanyin ^a,b,f  

^a Central Texas Veterans Health Care System   (United States)

^b SCOTT AND WHITE MEMORIAL HOSPITAL   (United States)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^d CHINA MEDICAL UNIVERSITY   (China)

^e SUN YAT SEN UNIVERSITY   (China)

^f TEXAS A M COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOINFORMATICS; CELL DEATH; CHEMICAL ACTIVATION; ELECTROPHORESIS; ETHANOL; IMMUNOLOGY; MAMMALS; POLYMERASE CHAIN REACTION; TRANSCRIPTION;

APOPTOTIC PATHWAYS; DOWNSTREAM TARGET; EXPRESSION LEVELS; HEPATIC STELLATE CELLS; HUMAN HEPATOCYTES; LUCIFERASE REPORTER ASSAYS; REGULATION OF TRANSCRIPTION; WESTERN-BLOT ANALYSIS;

RNA;

ALCOHOL; DEATH RECEPTOR 5; FAS LIGAND; FAS LIGAND 6; INTERLEUKIN 6; MICRORNA; MICRORNA 122; MICRORNA 127; MICRORNA 137; MICRORNA 181A; MICRORNA 181B; MICRORNA 192; MICRORNA 21; MICRORNA 34A; MICRORNA 409 5P; MICRORNA 509 3P; MICRORNA 871; MICRORNA 882; MICRORNA LET 7A; MICRORNA LET 7B; MICRORNA LET 7G; PROTEIN BCL XL; PROTEIN MCL 1; STAT3 PROTEIN; SURVIVIN; UNCLASSIFIED DRUG; MIRN21 MICRORNA, HUMAN; MIRN21 MICRORNA, MOUSE;

ALCOHOL ABUSE; ALCOHOL LIVER CIRRHOSIS; ALCOHOL LIVER DISEASE; ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BINDING SITE; BIOINFORMATICS; CELL DEATH; CELL SURVIVAL; CELL TRANSFORMATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DISEASE COURSE; FEMALE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; LIVER CELL; LUCIFERASE ASSAY; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; REAL TIME POLYMERASE CHAIN REACTION; RNA HYBRIDIZATION; SIGNAL TRANSDUCTION; STELLATE CELL; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION REGULATION; UPREGULATION; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; CYTOLOGY; GENETICS; LIVER; METABOLISM; PATHOPHYSIOLOGY;

ANIMALS; APOPTOSIS; HEPATIC STELLATE CELLS; HUMANS; INTERLEUKIN-6; LIVER; LIVER DISEASES, ALCOHOLIC; MICE; MICE, INBRED C57BL; MICRORNAS; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; UP-REGULATION;

EID: 84907482244     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.602383     Document Type: Article

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