Discovery and Fine-Mapping of Glycaemic and Obesity-Related Trait Loci Using High-Density Imputation

PLoS Genetics

Volumn 11, Issue 7, 2015, Pages

  Horikoshi, Momoko ^a,b   Mӓgi, Reedik ^c   van de Bunt, Martijn ^a,b   Surakka, Ida ^d,e   Sarin, Antti Pekka ^d,e   Mahajan, Anubha ^a   Marullo, Letizia ^f   Thorleifsson, Gudmar ^g   Hӓgg, Sara ^h,i   Hottenga, Jouke Jan ^j   Ladenvall, Claes ^k   Ried, Janina S ^l   Winkler, Thomas W ^m   Willems, Sara M ⁿ   Pervjakova, Natalia ^c   Esko, Tõnu ^c,o,p,q   Beekman, Marian ^r,s   Nelson, Christopher P ^t,u   Willenborg, Christina ^v,w   Wiltshire, Steven ^a,b   Ferreira, Teresa ^a   Fernandez, Juan ^a   Gaulton, Kyle J ^a   Steinthorsdottir, Valgerdur ^g   Hamsten, Anders ^h   Magnusson, Patrik K E ^h   Willemsen, Gonneke ^j   Milaneschi, Yuri ^x   Robertson, Neil R ^a,b   Groves, Christopher J ^b   Bennett, Amanda J ^b   Lehtimӓki, Terho ^y   Viikari, Jorma S ^z   Rung, Johan ^aa   Lyssenko, Valeriya ^k,ab   Perola, Markus ^d,e   Heid, Iris M ^m   Herder, Christian ^ac,ad   Grallert, Harald ^l   Müller Nurasyid, Martina ^l,ae,af   Roden, Michael ^ac,ad,ag   Hypponen, Elina ^ah,ai   Isaacs, Aaron ^n,aj   van Leeuwen, Elisabeth M ⁿ   Karssen, Lennart C ⁿ   Mihailov, Evelin ^c   Houwing Duistermaat, Jeanine J ^r   de Craen, Anton J M ^r,s   Deelen, Joris ^r,s   Havulinna, Aki S ^e   Blades, Matthew ^ak   Hengstenberg, Christian ^w,al   Erdmann, Jeanette ^v,w   Schunkert, Heribert ^w,al   Kaprio, Jaakko ^d,e   Tobin, Martin D ^u,ak   Samani, Nilesh J ^t,u   Lind, Lars ^am   Salomaa, Veikko ^e   Lindgren, Cecilia M ^a,p   Slagboom, P Eline ^r,s   Metspalu, Andres ^c,an   van Duijn, Cornelia M ^n,aj   Eriksson, Johan G ^d,e,ao,ap   Peters, Annette ^l   Gieger, Christian ^l   Jula, Antti ^e   Groop, Leif ^d,k   Raitakari, Olli T ^aq,ar   Power, Chris ^ai   Penninx, Brenda W J H ^x   de Geus, Eco ^j,x   Smit, Johannes H ^x   Boomsma, Dorret I ^j   Pedersen, Nancy L ^h   Ingelsson, Erik ^a,i   Thorsteinsdottir, Unnur ^g,as   Stefansson, Kari ^g,as   Ripatti, Samuli ^d,e,at   Prokopenko, Inga ^au   McCarthy, Mark I ^a,b,av   Morris, Andrew P ^a,c,aw   more..

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF TARTU   (Estonia)

^d UNIVERSITY OF HELSINKI   (Finland)

^e NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^f UNIVERSITY OF FERRARA   (Italy)

^g AMGEN INC   (United States)

^h KAROLINSKA INSTITUTE   (Sweden)

ⁱ UPPSALA UNIVERSITY   (Sweden)

^j VU UNIVERSITY AMSTERDAM   (Netherlands)

^k LUND UNIVERSITY   (Sweden)

^l INSTITUTE OF EPIDEMIOLOGY   (Germany)

^m UNIVERSITY OF REGENSBURG   (Germany)

ⁿ ERASMUS MEDICAL CENTER   (Netherlands)

^o BOSTON CHILDREN S HOSPITAL   (United States)

^p BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^q HARVARD MEDICAL SCHOOL   (United States)

^r LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^s Netherlands Consortium for Healthy Ageing   (Netherlands)

^t UNIVERSITY OF LEICESTER   (United Kingdom)

^u GLENFIELD HOSPITAL   (United Kingdom)

^v UNIVERSITY OF LÜBECK   (Germany)

^w DZHK GERMAN CENTRE FOR CARDIOVASCULAR RESEARCH   (Germany)

^x VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^y FIMLAB LABORATORIES   (Finland)

^z TURKU UNIVERSITY HOSPITAL   (Finland)

^aa EUROPEAN BIOINFORMATICS INSTITUTE   (United Kingdom)

^ab STENO DIABETES CENTER   (Denmark)

^ac HEINRICH HEINE UNIVERSITY   (Germany)

^ad LEIBNIZ CENTER FOR DIABETES RESEARCH AT HEINRICH HEINE UNIVERSITY DÜSSELDORF   (Germany)

^ae LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^af UNIVERSITY OF MUNICH   (Germany)

^ag UNIVERSITY HOSPITAL DÜSSELDORF   (Germany)

^ah UNIVERSITY OF SOUTH AUSTRALIA   (Australia)

^ai UNIVERSITY COLLEGE LONDON   (United Kingdom)

^aj Center for Medical Systems Biology   (Netherlands)

^ak UNIVERSITY OF LEICESTER   (United Kingdom)

^al TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^am UPPSALA UNIVERSITY HOSPITAL   (Sweden)

^an UNIVERSITY OF TARTU   (Estonia)

^ao FOLKHÄLSAN RESEARCH CENTER   (Finland)

^ap VAASA CENTRAL HOSPITAL   (Finland)

^aq UNIVERSITY OF TURKU   (Finland)

^ar UNIVERSITY OF TURKU   (Finland)

^as UNIVERSITY OF ICELAND   (Iceland)

^at WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^au IMPERIAL COLLEGE LONDON   (United Kingdom)

^av CHURCHILL HOSPITAL   (United Kingdom)

^aw UNIVERSITY OF LIVERPOOL   (United Kingdom)

more..

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOKINASE; GLUCOSE; G6PC2 PROTEIN, HUMAN; GERMINAL CENTER KINASES; GLUCOSE 6 PHOSPHATASE; PROTEIN SERINE THREONINE KINASE; RSPO3 PROTEIN, HUMAN; THROMBOSPONDIN;

ALLELE; ARTICLE; BINDING SITE; BODY MASS; G6PC2 GENE; GCK GENE; GENE; GENE LOCUS; GENE MAPPING; GENETIC ASSOCIATION; GENETIC VARIABILITY; GLYCEMIC CONTROL; HUMAN; IMPUTATION; OBESITY; PROMOTER REGION; QUANTITATIVE TRAIT LOCUS; QUANTITATIVE TRAIT LOCUS MAPPING; REGULATORY MECHANISM; RSPO3 GENE; STATISTICAL ANALYSIS; WAIST HIP RATIO; CHROMOSOMAL MAPPING; GENE FREQUENCY; GENETIC PREDISPOSITION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; GLYCEMIC INDEX; SINGLE NUCLEOTIDE POLYMORPHISM;

BODY MASS INDEX; CHROMOSOME MAPPING; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; GLUCOSE-6-PHOSPHATASE; GLYCEMIC INDEX; HUMANS; OBESITY; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEIN-SERINE-THREONINE KINASES; QUANTITATIVE TRAIT LOCI; THROMBOSPONDINS;

EID: 84938765668     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1005230     Document Type: Article

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