The effects of methylene blue on autophagy and apoptosis in MRI-defined normal tissue, ischemic penumbra and ischemic core

PLoS ONE

Volumn 10, Issue 6, 2015, Pages

  Jiang, Zhao ^a,b   Watts, Lora Talley ^b   Huang, Shiliang ^b   Shen, Qiang ^b   Rodriguez, Pavel ^b   Chen, Chunhua ^a,c   Zhou, Changman ^a   Duong, Timothy Q ^b  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^c UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 5; MAMMALIAN TARGET OF RAPAMYCIN; METHYLENE BLUE; PROTEIN BAK; PROTEIN BCL 2; PROTEIN P53; TUBERIN; ADENYLATE KINASE; BIOLOGICAL MARKER; PROTEIN BAX;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; BRAIN BLOOD FLOW; BRAIN INFARCTION; BRAIN ISCHEMIA; CELL DEATH; CONTROLLED STUDY; DIFFUSION; DIFFUSION WEIGHTED IMAGING; MALE; NEUROPROTECTION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PERFUSION; RAT; REPERFUSION INJURY; TRANSIENT ISCHEMIC ATTACK; TRAUMATIC BRAIN INJURY; WESTERN BLOTTING; ANIMAL; ANIMAL BEHAVIOR; BRAIN CIRCULATION; DRUG EFFECTS; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

RATTUS;

ADENYLATE KINASE; ANIMALS; APOPTOSIS; AUTOPHAGY; BCL-2-ASSOCIATED X PROTEIN; BEHAVIOR, ANIMAL; BIOMARKERS; BLOTTING, WESTERN; BRAIN INFARCTION; BRAIN ISCHEMIA; CEREBROVASCULAR CIRCULATION; MAGNETIC RESONANCE IMAGING; MALE; METHYLENE BLUE; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84938698600     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0131929     Document Type: Article

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