Expression of Notch1 correlates with breast cancer progression and prognosis

PLoS ONE

Volumn 10, Issue 6, 2015, Pages

  Yuan, Xun ^a   Zhang, Mingsheng ^a   Wu, Hua ^a   Xu, Hanxiao ^a   Han, Na ^a   Chu, Qian ^a   Yu, Shiying ^a   Chen, Yuan ^a   Wu, Kongming ^a  

^a HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

NOTCH1 RECEPTOR; TUMOR MARKER;

ARTICLE; BREAST CANCER; CANCER GROWTH; CANCER PROGNOSIS; CANCER STAGING; CANCER SURVIVAL; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE EXACERBATION; HUMAN; INTRADUCTAL CARCINOMA; MAJOR CLINICAL STUDY; OVERALL SURVIVAL; PROTEIN EXPRESSION; RECURRENCE FREE SURVIVAL; SURVIVAL TIME; TUMOR INVASION; BASAL CELL CARCINOMA; BREAST TUMOR; DISEASE COURSE; FEMALE; GENE EXPRESSION; GENETICS; META ANALYSIS; METABOLISM; MORTALITY; ODDS RATIO; PATHOLOGY; PROGNOSIS; PUBLISHING; SURVIVAL ANALYSIS;

BIOMARKERS, TUMOR; BREAST NEOPLASMS; DISEASE PROGRESSION; FEMALE; GENE EXPRESSION; HUMANS; NEOPLASMS, BASAL CELL; ODDS RATIO; PROGNOSIS; PUBLICATION BIAS; RECEPTOR, NOTCH1; SURVIVAL ANALYSIS;

EID: 84938675705     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0131689     Document Type: Article

References (49)

1. Siegel R, Ma J, Zou Z, Jemal A. Cancer statistics, 2014. CA Cancer J Clin.2014; 64: 9-29. doi: 10. 3322/caac.21208 PMID: 24399786
2. Grabher C, von Boehmer H, Look AT. Notch 1 activation in the molecular pathogenesis of T-cell acute lymphoblastic leukaemia. Nat Rev Cancer. 2006; 6: 347-359. PMID: 16612405
3. Gallahan D, Callahan R. The mouse mammary tumor associated gene INT3 is a unique member of the NOTCH gene family (NOTCH4). Oncogene. 1997; 14: 1883-1890. PMID: 9150355
4. Yuan X, Wu H, Xu H, Han N, Chu Q, Yu S, Chen Y, Wu K. Meta-analysis reveals the correlation of Notch signaling with non-small cell lung cancer progression and prognosis. Scientific reports. 2015 in press.
5. Suman S, Das TP, Damodaran C. Silencing NOTCH signaling causes growth arrest in both breast cancer stem cells and breast cancer cells. Br J Cancer. 2013; 109: 2587-2596. doi: 10.1038/bjc.2013.642 PMID: 24129237
6. Rizzo P, Miao H, D'Souza G, Osipo C, Song LL, Yun J, et al. Cross-talk between notch and the estrogen receptor in breast cancer suggests novel therapeutic approaches. Cancer Res. 2008; 68: 5226-5235. doi: 10.1158/0008-5472.CAN-07-5744 PMID: 18593923
7. Zhang N, Sun ZZ, Li F, Cao YW, Zhao CX, Liang WH, et al.Detection and clinical significance of Notch1 methylation in breast cancer and intraductal proliferative breast lesions. Zhonghua Bing Li Xue Za Zhi. 2011; 40: 324-329. PMID: 21756827
8. Farnie G, Clarke RB, Spence K, Pinnock N, Brennan K, Anderson NG, et al.Novel cell culture technique for primary ductal carcinoma in situ: role of Notch and epidermal growth factor receptor signaling pathways. J Natl Cancer Inst. 2007; 99: 616-627. PMID: 17440163
9. Zardawi SJ, Zardawi I, McNeil CM, Millar EK, McLeod D, Morey AL, et al. High Notch1 protein expression is an early event in breast cancer development and is associated with the HER-2 molecular subtype. Histopathology.2010; 56: 286-296. doi: 10.1111/j.1365-2559.2009.03475.x PMID: 20459529
10. Loi S, Haibe-Kains B, Majjaj S, Lallemand F, Durbecq V, Larsimont D, et al. PIK3CA mutations associated with gene signature of low mTORC1 signaling and better outcomes in estrogen receptor-positive breast cancer. Proc Natl Acad Sci U S A. 2010; 107: 10208-10213. doi: 10.1073/pnas.0907011107 PMID: 20479250
11. Pawitan Y, Bjöhle J, Amler L, Borg AL, Egyhazi S, Hall P, et al. Gene expression profiling spares early breast cancer patients from adjuvant therapy: derived and validated in two population-based cohorts. Breast Cancer Res. 2005; 7: R953-964. PMID: 16280042
12. Desmedt C, Piette F, Loi S, Wang Y, Lallemand F, Haibe-Kains B, et al. Strong time dependence of the 76-gene prognostic signature for node-negative breast cancer patients in the TRANSBIG multicenter independent validation series. Clin Cancer Res. 2007; 13: 3207-3214. PMID: 17545524
13. Schmidt M, Böhm D, von Törne C, Steiner E, Puhl A, Pilch H, et al.The humoral immune system has a key prognostic impact in node-negative breast cancer. Cancer Res. 2008; 68: 5405-5413. doi: 10. 1158/0008-5472.CAN-07-5206 PMID: 18593943
14. Minn AJ, Gupta GP, Siegel PM, Bos PD, Shu W, Giri DD, et al. Genes that mediate breast cancer metastasis to lung.Nature.2005; 436: 518-524. PMID: 16049480
15. Ercan C, Vermeulen JF, Hoefnagel L, Bult P, van der Groep P, van der Wall E, et al. HIF-1alpha and NOTCH signaling in ductal and lobular carcinomas of the breast. Cell Oncol (Dordr). 2012; 35: 435-442.
16. Reedijk M, Odorcic S, Chang L, Zhang H, Miller N, McCready DR, et al. High-level coexpression of JAG1 and NOTCH1 is observed in human breast cancer and is associated with poor overall survival. Cancer Res. 2005; 65: 8530-8537. PMID: 16166334
17. Kao KJ, Chang KM, Hsu HC, Huang AT. Correlation of microarray-based breast cancer molecular subtypes and clinical outcomes: implications for treatment optimization. BMC Cancer.2011; 11: 143. doi: 10.1186/1471-2407-11-143 PMID: 21501481
18. Naderi A, Teschendorff AE, Barbosa-Morais NL, Pinder SE, Green AR, Powe DG, et al. A gene-expression signature to predict survival in breast cancer across independent data sets.Oncogene.2007; 26: 1507-1516. PMID: 16936776
19. Hatzis C, Pusztai L, Valero V, Booser DJ, Esserman L, Lluch A, et al. A genomic predictor of response and survival following taxane-anthracycline chemotherapy for invasive breast cancer. JAMA. 2011; 305: 1873-1881. doi: 10.1001/jama.2011.593 PMID: 21558518
20. Wang Y, Klijn JG, Zhang Y, Sieuwerts AM, Look MP, Yang F, et al. Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer. Lancet.2005; 365: 671-679. PMID: 15721472
21. Pallavi SK, Ho DM, Hicks C, Miele L, Artavanis-Tsakonas S. Notch and Mef2 synergize to promote proliferation and metastasis through JNK signal activation in Drosophila. EMBOJ. 2012; 31: 2895-2907.
22. Mittal S, Subramanyam D, Dey D, Kumar RV, Rangarajan A. Cooperation of Notch and Ras/MAPK signaling pathways in human breast carcinogenesis. Mol Cancer. 2009; 8: 128. doi: 10.1186/1476-4598-8-128 PMID: 20030805
23. Tierney JF, Stewart LA, Ghersi D, Burdett S, Sydes MR. Practical methods for incorporating summary time-to-event data into meta-analysis. Trials. 2007; 8: 16. PMID: 17555582
24. Stroup DF, Berlin JA, Morton SC, Olkin I, Williamson GD, Rennie D, et al. Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group. JAMA. 2000; 283: 2008-2012. PMID: 10789670
25. Yao K, Rizzo P, Rajan P, Albain K, Rychlik K, Shah S, et al. Notch-1 and notch-4 receptors as prognostic markers in breast cancer. Int J Surg Pathol. 2011; 19: 607-613. doi: 10.1177/1066896910362080 PMID: 20444726
26. Dong XB, Ji CY, Ma DX, Ma R, Zang SL, Yu HQ, et al. [Notch signaling in human breast cancer]. Zhonghua Zhong Liu Za Zhi.2007; 29: 425-428. PMID: 17974275
27. Hua BL, Fu XG, Hu WH, Yin L, Kang XL, Li HA, et al. Notch1 mRNA and protein expression in human breast cancer and normal mammary gland tissues. Zhonghua Bing Li Xue Za Zhi.2009; 38: 806-809. PMID: 20193454
28. Liu Z, Teng L, Bailey SK, Frost AR, Bland KI, LoBuglio AF, et al. Epithelial transformation by KLF4 requires Notch1 but not canonical Notch1 signaling. Cancer Biol Ther. 2009; 8: 1840-1851. PMID: 19717984
29. Ma D, Dong X, Zang S, Ma R, Zhao P, Guo D, et al. Aberrant expression and clinical correlation of Notch signaling molecules in breast cancer of Chinese population. Asia Pac J Clin Oncol. 2011; 7: 385-391. doi: 10.1111/j.1743-7563.2011.01433.x PMID: 22151989
30. De Craene B, Berx G. Regulatory networks defining EMT during cancer initiation and progression. Nat Rev Cancer.2013; 13: 97-110. doi: 10.1038/nrc3447 PMID: 23344542
31. Mittal S, Sharma A, Balaji SA, Gowda MC, Dighe RR, Kumar RV, et al. Coordinate hyperactivation of Notch1 and Ras/MAPK pathways correlates with poor patient survival: novel therapeutic strategy for aggressive breast cancers. Mol Cancer Ther. 2014; 13:3198-209. doi: 10.1158/1535-7163.MCT-14-0280 PMID: 25253780
32. Andersson ER, Lendahl U. Therapeutic modulation of Notch signalling-are we there yet?Nat Rev Drug Discov. 2014; 13:357-78. doi: 10.1038/nrd4252 PMID: 24781550
33. Yuan X, Wu H, Han N, Xu H, Chu Q, Wu K. Notch signaling in non-small cell lung cancer: biological significance and therapeutic application. J Hematol Oncol. 2014; 7:87. doi: 10.1186/s13045-014-0087-z PMID: 25477004
34. Liao Y, He X, Qiu H, Che Q, Wang F, Lu W, et al. Suppression of the epithelial-mesenchymal transition by SHARP1 is linked to the NOTCH1 signaling pathway in metastasis of endometrial cancer.BMC Cancer. 2014; 14:487. doi: 10.1186/1471-2407-14-487 PMID: 24997474
35. Zhou Q, Wang Y, Peng B, Liang L, Li J. The roles of Notch1 expression in the migration of intrahepatic cholangiocarcinoma.BMC Cancer. 2013 May 20; 13:244. doi: 10.1186/1471-2407-13-244 PMID: 23688168
36. Shao S, Zhao X, Zhang X, Luo M, Zuo X, Huang S, et al. Notch1 signaling regulates the epithelial¿mesenchymal transition and invasion of breast cancer in a Slug-dependent manner. Mol Cancer. 2015; 14: 28. doi: 10.1186/s12943-015-0295-3 PMID: 25645291
37. Cancer Genome Atlas Network.Comprehensive molecular portraits of human breast tumours.Nature. 2012; 490:61-70. doi: 10.1038/nature11412 PMID: 23000897
38. Martz CA, Ottina KA, Singleton KR, Jasper JS, Wardell SE, Peraza-Penton A, et al. Systematic identification of signaling pathways with potential to confer anticancer drug resistance. Sci Signal. 2014; 7: ra121. doi: 10.1126/scisignal.aaa1877 PMID: 25538079
39. Portanova P, Notaro A, Pellerito O, Sabella S, Giuliano M, Calvaruso G. Notch inhibition restores TRAIL-mediated apoptosis via AP1-dependent upregulation of DR4 and DR5 TRAIL receptors in MDA-MB-231 breast cancer cells.Int J Oncol. 2013; 43:121-130. doi: 10.3892/ijo.2013.1945 PMID: 23686163
40. Colbert LS, Wilson K, Kim S, Liu Y, Oprea-Ilies G, Gillespie C, et al. NILCO biomarkers in breast cancer from Chinese patients.BMC Cancer. 2014; 14:249. doi: 10.1186/1471-2407-14-249 PMID: 24716804
41. Wang K, Zhang Q, Li D, Ching K, Zhang C, Zheng X, et al. PEST Domain Mutations in Notch Receptors Comprise an Oncogenic Driver Segment in Triple-Negative Breast Cancer Sensitive to a γ-Secretase Inhibitor. Clin Cancer Res. 2015; 21:1487-96. doi: 10.1158/1078-0432.CCR-14-1348 PMID: 25564152
42. Zhang X, Zhao X, Shao S, Zuo X, Ning Q, Luo M, et al. Notch1 induces epithelial-mesenchymal transition and the cancer stem cell phenotype in breast cancer cells and STAT3 plays a key role. Int J Oncol. 2015; 46:1141-8 doi: 10.3892/ijo.2014.2809 PMID: 25544568
43. Azzam DJ, Zhao D, Sun J, Minn AJ, Ranganathan P, Drews-Elger K, et al. Triple negative breast cancer initiating cell subsets differ in functional and molecular characteristics and in γ-secretase inhibitor drug responses. EMBO Mol Med. 2013; 5:1502-1522. doi: 10.1002/emmm.201302558 PMID: 23982961
44. Franci C, Zhou J, Jiang Z, Modrusan Z, Good Z, Jackson E, et al. Biomarkers of residual disease, disseminated tumor cells, and metastases in the MMTV-PyMTbreast cancer model. PLoS One. 2013; 8 (3):e58183. doi: 10.1371/journal.pone.0058183 PMID: 23520493
45. Qiu M, Peng Q, Jiang I, Carroll C, Han G, Rymer I, et al.Specific inhibition of Notch1 signaling enhances the antitumor efficacy of chemotherapy in triple negative breast cancer through reduction of cancer stem cells.Cancer Lett. 2013; 328:261-270. doi: 10.1016/j.canlet.2012.09.023 PMID: 23041621
46. Zhang CC, Pavlicek A, Zhang Q, Lira ME, Painter CL, Yan Z, et al.Biomarker and pharmacologic evaluation of the γ-secretase inhibitor PF-03084014 in breast cancermodels.ClinCancer Res. 2012; 18:5008-5019.
47. Mao J, Song B, Shi Y, Wang B, Fan S, Yu X, et al. ShRNA targeting Notch1 sensitizes breast cancer stem cell to paclitaxel. Int J Biochem Cell Biol. 2013; 45: 1064-1073. doi: 10.1016/j.biocel.2013.02.022 PMID: 23500524
48. Cao YW, Li WQ, Wan GX, Li YX, Du XM, Li YC, et al. Correlation and prognostic value of SIRT1 and Notch1 signaling in breast cancer. J Exp Clin Cancer Res. 2014; 33:97. doi: 10.1186/s13046-014-0097-2 PMID: 25420528
49. Stoeck A, Lejnine S, Truong A, Pan L, Wang H, Zang C, et al. Discovery of biomarkers predictive of GSI response in triple-negative breast cancer and adenoid cystic carcinoma. Cancer Discov. 2014; 4:1154-67. doi: 10.1158/2159-8290.CD-13-0830 PMID: 25104330