Triple negative breast cancer initiating cell subsets differ in functional and molecular characteristics and in γ-secretase inhibitor drug responses

EMBO Molecular Medicine

Volumn 5, Issue 10, 2013, Pages 1502-1522

  Azzam, Diana J ^a,b   Zhao, Dekuang ^a,c   Sun, Jun ^a   Minn, Andy J ^d   Ranganathan, Prathibha ^a   Drews Elger, Katherine ^a   Han, Xiaoqing ^a,c   Picon Ruiz, Manuel ^a   Gilbert, Candace A ^a   Wander, Seth A ^a,c   Capobianco, Anthony J ^a,b   El Ashry, Dorraya ^a,b   Slingerland, Joyce M ^a,b,c  

^a UNIVERSITY OF MIAMI   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^c Sheila and David Fuente Cancer Biology Program   (United States)

^d UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

Breast cancer stem cells; GSI; Metastasis; Notch1; Sox2

Indexed keywords

ALDEHYDE DEHYDROGENASE; CD24 ANTIGEN; ESTROGEN RECEPTOR; GAMMA SECRETASE INHIBITOR; HERMES ANTIGEN; NOTCH1 RECEPTOR; TRANSCRIPTION FACTOR SOX2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CARCINOGENICITY; CELL INVASION; CELL MOTILITY; DILUTION; DRUG EFFICACY; DRUG RESPONSE; GENE EXPRESSION; HUMAN; HUMAN CELL; METASTASIS POTENTIAL; NONHUMAN; PRIORITY JOURNAL; PROGENY; T LYMPHOCYTE SUBPOPULATION; TRIPLE NEGATIVE BREAST CANCER;

BREAST CANCER STEM CELLS; GSI; METASTASIS; NOTCH1; SOX2;

AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ANTIGENS, CD24; ANTIGENS, CD44; ANTINEOPLASTIC AGENTS; CELL PROLIFERATION; ENZYME INHIBITORS; FEMALE; HUMANS; ISOENZYMES; MCF-7 CELLS; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASTIC STEM CELLS; RECEPTORS, NOTCH; RETINAL DEHYDROGENASE; SOXB1 TRANSCRIPTION FACTORS; TRIPLE NEGATIVE BREAST NEOPLASMS; TUMOR CELLS, CULTURED;

EID: 84884969557     PISSN: 17574676     EISSN: 17574684     Source Type: Journal    
DOI: 10.1002/emmm.201302558     Document Type: Article

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