Astaxanthin improves cognitive deficits from oxidative stress, nitric oxide synthase and inflammation through upregulation of PI3K/Akt in diabetes rat

International Journal of Clinical and Experimental Pathology

Volumn 8, Issue 6, 2015, Pages 6083-6094

  Xu, Lianbao ^a,b   Zhu, Juan ^b   Yin, Weibing ^a   Ding, Xinsheng ^a  

^a THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^b THE AFFILIATED DRUM TOWER HOSPITAL OF NANJING UNIVERSITY MEDICAL SCHOOL   (China)

Author keywords

Astaxanthin; Diabetes induced cognitive deficit; Inflammatory; Nitric oxide synthase; Oxidative stress; PI3K Akt

Indexed keywords

ANTIINFLAMMATORY AGENT; ANTIOXIDANT; ASTAXANTHIN; AUTACOID; CASP3 PROTEIN, RAT; CASP9 PROTEIN, RAT; CASPASE 3; CASPASE 9; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUCOSE BLOOD LEVEL; INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE; NOS2 PROTEIN, RAT; NOS3 PROTEIN, RAT; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; XANTHOPHYLL;

ANIMAL; BODY WEIGHT; BRAIN; COGNITION; COGNITION DISORDERS; COMPLICATION; DIABETES MELLITUS, EXPERIMENTAL; DRUG EFFECTS; ENZYMOLOGY; GLUCOSE BLOOD LEVEL; IMMUNOLOGY; INFLAMMATION; MALE; METABOLISM; OXIDATIVE STRESS; PSYCHOLOGY; SIGNAL TRANSDUCTION; TIME FACTOR; WISTAR RAT;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIOXIDANTS; BLOOD GLUCOSE; BODY WEIGHT; BRAIN; CASPASE 3; CASPASE 9; COGNITION; COGNITION DISORDERS; DIABETES MELLITUS, EXPERIMENTAL; INFLAMMATION; INFLAMMATION MEDIATORS; MALE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III; OXIDATIVE STRESS; PHOSPHATIDYLINOSITOL 3-KINASE; PROTO-ONCOGENE PROTEINS C-AKT; RATS, WISTAR; SIGNAL TRANSDUCTION; TIME FACTORS; XANTHOPHYLLS;

EID: 84938579232     PISSN: None     EISSN: 19362625     Source Type: Journal    
DOI: None     Document Type: Article

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