Parasite-induced ER stress response in hepatocytes facilitates Plasmodium liver stage infection

EMBO Reports

Volumn 16, Issue 8, 2015, Pages 955-964

  Inácio, Patricia ^a   Zuzarte Luís, Vanessa ^a   Ruivo, Margarida T G ^a   Falkard, Brie ^b   Nagaraj, Nagarjuna ^c   Rooijers, Koos ^d   Mann, Matthias ^c   Mair, Gunnar ^e   Fidock, David A ^b   Mota, Maria M ^a  

^a INSTITUTO DE MEDICINA MOLECULAR   (Portugal)

^b Department of Medicine   (United States)

^c MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^d NETHERLANDS CANCER INSTITUTE   (Netherlands)

^e UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

CREBH; liver; Plasmodium; UPR; XBP1

Indexed keywords

TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR CREBH; UNCLASSIFIED DRUG; X BOX BINDING PROTEIN 1; DNA BINDING PROTEIN; REGULATORY FACTOR X TRANSCRIPTION FACTOR; XBP1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL SPECIFICITY; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; FEMALE; HEPATITIS; HOST PARASITE INTERACTION; HUMAN; IN VIVO STUDY; LIVER CELL; LIVER DEVELOPMENT; MALE; MOUSE; NONHUMAN; PLASMODIUM BERGHEI INFECTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEOMICS; SIGNAL TRANSDUCTION; TRANSCRIPTOMICS; UNFOLDED PROTEIN RESPONSE; ANIMAL; C57BL MOUSE; GENE EXPRESSION PROFILING; GENETICS; GROWTH, DEVELOPMENT AND AGING; LIFE CYCLE STAGE; MALARIA; PARASITE LOAD; PARASITOLOGY; PATHOGENICITY; PATHOPHYSIOLOGY; PHYSIOLOGY; PLASMODIUM BERGHEI; ULTRASTRUCTURE;

MAMMALIA; PLASMODIUM BERGHEI; PLASMODIUM PARASITES;

ANIMALS; DNA-BINDING PROTEINS; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION PROFILING; HEPATOCYTES; HOST-PARASITE INTERACTIONS; LIFE CYCLE STAGES; MALARIA; MALE; MICE, INBRED C57BL; PARASITE LOAD; PLASMODIUM BERGHEI; PROTEOMICS; REGULATORY FACTOR X TRANSCRIPTION FACTORS; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; UNFOLDED PROTEIN RESPONSE; X-BOX BINDING PROTEIN 1;

EID: 84938576451     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.15252/embr.201439979     Document Type: Article

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