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Volumn 11, Issue 15, 2015, Pages 2205-2219

Next revolution in molecular theranostics: Personalized medicine for urologic cancers

Author keywords

bombesin; carbonic anhydrase; kidney cancer; neurotensin; prostate cancer; PSMA; theranostics

Indexed keywords

BOMBESIN; CARBONATE DEHYDRATASE IX; NEUROPEPTIDE RECEPTOR; NEUROTENSIN; PROSTATE SPECIFIC MEMBRANE ANTIGEN; CA9 PROTEIN, HUMAN; CARBONATE DEHYDRATASE; GLUTAMATE CARBOXYPEPTIDASE II; GLUTAMATE CARBOXYPEPTIDASE II, HUMAN; MEMBRANE ANTIGEN; TUMOR ANTIGEN; TUMOR MARKER;

EID: 84938537050     PISSN: 14796694     EISSN: 17448301     Source Type: Journal    
DOI: 10.2217/fon.15.104     Document Type: Review
Times cited : (13)

References (124)
  • 1
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 144(5), 646-674 (2011
    • (2011) Cell , vol.144 , Issue.5 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 2
    • 10344244481 scopus 로고    scopus 로고
    • Geographical patterns and time trends of cancer incidence and survival among children and adolescents in Europe since the 1970s (the ACCIS project): An epidemiological study
    • Steliarova-Foucher E, Stiller C, Kaatsch P et al. Geographical patterns and time trends of cancer incidence and survival among children and adolescents in Europe since the 1970s (the ACCIS project): An epidemiological study. Lancet 364(9451), 2097-2105 (2004
    • (2004) Lancet , vol.364 , Issue.9451 , pp. 2097-2105
    • Steliarova-Foucher, E.1    Stiller, C.2    Kaatsch, P.3
  • 3
    • 84857097049 scopus 로고    scopus 로고
    • History of cancer, ancient and modern treatment methods
    • Sudhakar A. History of cancer, ancient and modern treatment methods. J. Cancer Sci. Ther. 1(2), 1-4 (2009
    • (2009) J. Cancer Sci. Ther , vol.1 , Issue.2 , pp. 1-4
    • Sudhakar, A.1
  • 4
    • 77954827460 scopus 로고    scopus 로고
    • The path to personalized medicine
    • Hamburg M, Collins F. The path to personalized medicine. N. Engl J. Med. 363, 301-304 (2010
    • (2010) N. Engl J. Med , vol.363 , pp. 301-304
    • Hamburg, M.1    Collins, F.2
  • 5
    • 79956311993 scopus 로고    scopus 로고
    • Molecular diagnostics in urologic malignancies: A work in progress
    • Netto G. Molecular diagnostics in urologic malignancies: A work in progress. Arch. Pathol. Lab. Med. 135(5), 610-621 (2011
    • (2011) Arch. Pathol. Lab. Med , vol.135 , Issue.5 , pp. 610-621
    • Netto, G.1
  • 7
    • 84880473776 scopus 로고    scopus 로고
    • Personalizing oncology: Perspectives and prospects
    • Mendelsohn J. Personalizing oncology: perspectives and prospects. J. Clin. Oncol. 31(15), 1904-1911 (2013
    • (2013) J. Clin. Oncol , vol.31 , Issue.15 , pp. 1904-1911
    • Mendelsohn, J.1
  • 8
    • 80054821668 scopus 로고    scopus 로고
    • Theranostics: Combining imaging and therapy
    • Kelkar SS, Reineke TM. Theranostics: combining imaging and therapy. Bioconjug. Chem. 22, 1879-1903 (2011)
    • (2011) Bioconjug. Chem , vol.22 , pp. 1879-1903
    • Kelkar, S.S.1    Reineke, T.M.2
  • 9
    • 84904687739 scopus 로고    scopus 로고
    • Co-development of diagnostic vectors to support targeted therapies and theranostics: Essential tools in personalized cancer therapy
    • Nicolaides NC, O'Shannessy DJ, Albone E, Grasso L. Co-development of diagnostic vectors to support targeted therapies and theranostics: essential tools in personalized cancer therapy. Front Oncol. 13(4), 141-155 (2014
    • (2014) Front Oncol , vol.13 , Issue.4 , pp. 141-155
    • Nicolaides, N.C.1    O'Shannessy, D.J.2    Albone, E.3    Grasso, L.4
  • 10
    • 84905920762 scopus 로고    scopus 로고
    • Theranostics and contrast-agents for medical imaging: A pharmaceutical company viewpoint
    • Idée JM, Louguet S, Ballet S, Corot C. Theranostics and contrast-agents for medical imaging: A pharmaceutical company viewpoint. Quant. Imaging Med. Surg. 3(6), 292-297 (2013
    • (2013) Quant. Imaging Med. Surg , vol.3 , Issue.6 , pp. 292-297
    • Idée, J.M.1    Louguet, S.2    Ballet, S.3    Corot, C.4
  • 12
    • 79952351439 scopus 로고    scopus 로고
    • Globalization of P4 medicine: Predictive, personalized, preemptive, and participatory - Summary of the proceedings of the Eighth International Symposium of the International Society for Strategic Studies in Radiology
    • 2011
    • Bradley WG, Golding SG, Herold CJ et al. Globalization of P4 medicine: predictive, personalized, preemptive, and participatory - summary of the proceedings of the Eighth International Symposium of the International Society for Strategic Studies in Radiology, 2009. Radiology 258(2), 571-582 (2011
    • (2009) Radiology , vol.258 , Issue.2 , pp. 571-582
    • Bradley, W.G.1    Golding, S.G.2    Herold, C.J.3
  • 13
    • 84905435584 scopus 로고    scopus 로고
    • Targeting tumor microenvironment: Crossing tumor interstitial fluid by multifunctional nanomedicines
    • Omidi Y, Barar J. Targeting tumor microenvironment: crossing tumor interstitial fluid by multifunctional nanomedicines. Bio Impacts 4(2), 55-67 (2014
    • (2014) Bio Impacts , vol.4 , Issue.2 , pp. 55-67
    • Omidi, Y.1    Barar, J.2
  • 14
    • 84899859103 scopus 로고    scopus 로고
    • Histopathological determinants of tumor resistance: A special look to the immunohistochemical expression of carbonic anhydrase IX in human cancers
    • Ilardi G, Zambrano N, Merolla F et al. Histopathological determinants of tumor resistance: A special look to the immunohistochemical expression of carbonic anhydrase IX in human cancers. Curr. Med. Chem. 21(14), 1569-1582 (2014
    • (2014) Curr. Med. Chem , vol.21 , Issue.14 , pp. 1569-1582
    • Ilardi, G.1    Zambrano, N.2    Merolla, F.3
  • 15
    • 84893522300 scopus 로고    scopus 로고
    • Carbonic anhydrase IX, a hypoxia-induced catalytic component of the pH regulating machinery in tumors
    • Sedlakova O, Svastova E, Takacova M, Kopacek J, Pastorek J, Pastorekova S. Carbonic anhydrase IX, a hypoxia-induced catalytic component of the pH regulating machinery in tumors. Front. Physiol. 4, 400-414 (2013
    • (2013) Front. Physiol , vol.4 , pp. 400-414
    • Sedlakova, O.1    Svastova, E.2    Takacova, M.3    Kopacek, J.4    Pastorek, J.5    Pastorekova, S.6
  • 16
    • 48349111944 scopus 로고    scopus 로고
    • Adaptation to hypoxia and acidosis in carcinogenesis and tumor progression
    • Fang JS, Gillies RD, Gatenby RA. Adaptation to hypoxia and acidosis in carcinogenesis and tumor progression. Semin. Cancer Biol. 18(5), 330-337 (2008
    • (2008) Semin. Cancer Biol , vol.18 , Issue.5 , pp. 330-337
    • Fang, J.S.1    Gillies, R.D.2    Gatenby, R.A.3
  • 17
    • 0029975564 scopus 로고    scopus 로고
    • Human MN/CA9 gene, a novel member of the carbonic anhydrase family: Structure and exon to protein domain relationships
    • Opavsky R, Pastorekova S, Zelnik V et al. Human MN/CA9 gene, a novel member of the carbonic anhydrase family: structure and exon to protein domain relationships. Genomics 33, 480-487 (1996
    • (1996) Genomics , vol.33 , pp. 480-487
    • Opavsky, R.1    Pastorekova, S.2    Zelnik, V.3
  • 18
    • 0028111173 scopus 로고
    • Cloning and characterization of MN, a human tumor-associated protein with a domain homologous to carbonic anhydrase and a putative helix-loop-helix DNA binding segment
    • Pastorek J, Pastorekova S, Callebaut I et al. Cloning and characterization of MN, a human tumor-associated protein with a domain homologous to carbonic anhydrase and a putative helix-loop-helix DNA binding segment. Oncogene 9, 2877-2888 (1994
    • (1994) Oncogene , vol.9 , pp. 2877-2888
    • Pastorek, J.1    Pastorekova, S.2    Callebaut, I.3
  • 19
    • 0034099829 scopus 로고    scopus 로고
    • Molecular cloning and immunogenicity of renal cell carcinoma-associated antigen G250.
    • Grabmaier K, Vissers JL, De Weijert MC et al. Molecular cloning and immunogenicity of renal cell carcinoma-associated antigen G250. Int. J. Cancer 85, 865-870 (2000
    • (2000) Int. J. Cancer , vol.85 , pp. 865-870
    • Grabmaier, K.1    Vissers, J.L.2    De Weijert, M.C.3
  • 20
    • 0031040821 scopus 로고    scopus 로고
    • Carbonic anhydrase IX MN/CA IX: Analysis of stomach complementary DNA sequence and expression in human and rat alimentary tracts
    • Pastorekova S, Parkkila S, Parkkila AK et al. Carbonic anhydrase IX, MN/CA IX: Analysis of stomach complementary DNA sequence and expression in human and rat alimentary tracts. Gastroenterology 112, 398-408 (1997
    • (1997) Gastroenterology , vol.112 , pp. 398-408
    • Pastorekova, S.1    Parkkila, S.2    Parkkila, A.K.3
  • 21
    • 0033036495 scopus 로고    scopus 로고
    • Immunohistochemical analysis of tumor antigen saturation following injection of monoclonal antibody G250.
    • Steffens MG, Oosterwijk-Wakka JC, Zegwaart-Hagemeier NE et al. Immunohistochemical analysis of tumor antigen saturation following injection of monoclonal antibody G250. AntiCancer Res. 19, 1197-1200 (1999
    • (1999) AntiCancer Res , vol.19 , pp. 1197-1200
    • Steffens, M.G.1    Oosterwijk-Wakka, J.C.2    Zegwaart-Hagemeier, N.E.3
  • 22
    • 15644384121 scopus 로고    scopus 로고
    • Immunohistochemistry of carbonic anhydrase isozyme IX (MN/CA IX) in human gut reveals polarized expression in the epithelial cells with the highest proliferative capacity
    • Saarnio J, Parkkila S, Parkkila AK et al. Immunohistochemistry of carbonic anhydrase isozyme IX (MN/CA IX) in human gut reveals polarized expression in the epithelial cells with the highest proliferative capacity. J. Histochem. Cytochem. 46, 497-504 (1998
    • (1998) J. Histochem. Cytochem , vol.46 , pp. 497-504
    • Saarnio, J.1    Parkkila, S.2    Parkkila, A.K.3
  • 23
    • 0034944417 scopus 로고    scopus 로고
    • Expression of the transmembrane carbonic anhydrases, CA IX and CA XII, in the human male excurrent ducts
    • Karhumaa P, Kaunisto K, Parkkila S et al. Expression of the transmembrane carbonic anhydrases, CA IX and CA XII, in the human male excurrent ducts. Mol. Hum. Reprod. 7, 611-616 (2001
    • (2001) Mol. Hum. Reprod , vol.7 , pp. 611-616
    • Karhumaa, P.1    Kaunisto, K.2    Parkkila, S.3
  • 24
    • 0033775150 scopus 로고    scopus 로고
    • Expression of transmembrane carbonic anhydrase isoenzymes IX and XII in normal human pancreas and pancreatic tumours
    • Kivela AJ, Parkkila S, Saarnio J et al. Expression of transmembrane carbonic anhydrase isoenzymes IX and XII in normal human pancreas and pancreatic tumours. Histochem. Cell Biol. 114, 197-204 (2000
    • (2000) Histochem. Cell Biol , vol.114 , pp. 197-204
    • Kivela, A.J.1    Parkkila, S.2    Saarnio, J.3
  • 25
    • 44949119410 scopus 로고    scopus 로고
    • Low CAIX expression and absence of VHL gene mutation are associated with tumor aggressiveness and poor survival of clear cell renal cell carcinoma
    • Patard JJ, Fergelot P, Karakiewicz P et al. Low CAIX expression and absence of VHL gene mutation are associated with tumor aggressiveness and poor survival of clear cell renal cell carcinoma. Int. J. Cancer 123(2), 395-400 (2008
    • (2008) Int. J. Cancer , vol.123 , Issue.2 , pp. 395-400
    • Patard, J.J.1    Fergelot, P.2    Karakiewicz, P.3
  • 26
    • 62749124795 scopus 로고    scopus 로고
    • Transcriptional control of the tumor-and hypoxia-marker carbonic anhydrase 9: A one transcription factor (HIF-1) show?
    • Kaluz S, Kaluzova M, Liao SY, Lerman M, Stanbridge EJ. Transcriptional control of the tumor-and hypoxia-marker carbonic anhydrase 9: A one transcription factor (HIF-1) show?. Biochim. Biophys. Acta. 1795, 162-172 (2009
    • (2009) Biochim. Biophys. Acta , vol.1795 , pp. 162-172
    • Kaluz, S.1    Kaluzova, M.2    Liao, S.Y.3    Lerman, M.4    Stanbridge, E.J.5
  • 27
    • 22544464403 scopus 로고    scopus 로고
    • Coordinate regulation of the oxygen-dependent degradation domains of hypoxia-inducible factor 1α
    • Chan D, Sutphin P, Yen SR, Giaccia A. Coordinate regulation of the oxygen-dependent degradation domains of hypoxia-inducible factor 1α. Mol. Cell. Biol. 5(15), 6415-6426 (2005
    • (2005) Mol. Cell. Biol , vol.5 , Issue.15 , pp. 6415-6426
    • Chan, D.1    Sutphin, P.2    Yen, S.R.3    Giaccia, A.4
  • 29
    • 0348047338 scopus 로고    scopus 로고
    • Quantification of G250 MRNA expression in renal epithelial neoplasms by real-time reverse transcription-PCR of dissected tissue from paraffin sections
    • Bismar TA, Bianco FJ, Zhang H et al. Quantification of G250 Mrna expression in renal epithelial neoplasms by real-time reverse transcription-PCR of dissected tissue from paraffin sections. Pathology 35, 513-517 (2003
    • (2003) Pathology , vol.35 , pp. 513-517
    • Bismar, T.A.1    Bianco, F.J.2    Zhang, H.3
  • 30
    • 67649791966 scopus 로고    scopus 로고
    • CA9 gene: Single nucleotide polymorphism predicts metastatic renal cell carcinoma prognosis
    • De Martino M, Klatte T, Seligson DB et al. CA9 gene: single nucleotide polymorphism predicts metastatic renal cell carcinoma prognosis. J. Urol. 82, 728-734 (2009
    • (2009) J. Urol , vol.82 , pp. 728-734
    • De Martino, M.1    Klatte, T.2    Seligson, D.B.3
  • 31
    • 84961289871 scopus 로고    scopus 로고
    • The high-dose aldesleukin "select" trial: A trial to prospectively validate predictive models of response to treatment in patients with metastatic renal cell carcinoma
    • McDermott DF, Cheng SC, Signoretti S et al. The high-dose aldesleukin "select" trial: A trial to prospectively validate predictive models of response to treatment in patients with metastatic renal cell carcinoma. Clin. Cancer Res. 21(3), 561-568 (2015
    • (2015) Clin. Cancer Res , vol.21 , Issue.3 , pp. 561-568
    • McDermott, D.F.1    Cheng, S.C.2    Signoretti, S.3
  • 32
    • 1542398693 scopus 로고    scopus 로고
    • Randomized phase II study of multiple dose levels of CCI-779, a novel mammalian target of rapamycin kinase inhibitor, in patients with advanced refractory renal cell carcinoma
    • Atkins MB, Hidalgo M, Stadler WM et al. Randomized phase II study of multiple dose levels of CCI-779, a novel mammalian target of rapamycin kinase inhibitor, in patients with advanced refractory renal cell carcinoma. J. Clin. Oncol. 22, 909-918 (2004
    • (2004) J. Clin. Oncol , vol.22 , pp. 909-918
    • Atkins, M.B.1    Hidalgo, M.2    Stadler, W.M.3
  • 33
    • 35348858663 scopus 로고    scopus 로고
    • Potential histologic andmolecular predictors of response to temsirolimus in patients with advanced renal cell carcinoma
    • Cho D, Signoretti S, Dabora S et al. Potential histologic andmolecular predictors of response to temsirolimus in patients with advanced renal cell carcinoma. Clin. Genitourin. Cancer 5, 379-385 (2007
    • (2007) Clin. Genitourin. Cancer , vol.5 , pp. 379-385
    • Cho, D.1    Signoretti, S.2    Dabora, S.3
  • 34
    • 54549110005 scopus 로고    scopus 로고
    • Prognostic value of the co-expression of carbonic anhydrase IX and vascular endothelial growth factor in patients with clear cell renal cell carcinoma
    • Phuoc NB, Ehara H, Gotoh T et al. Prognostic value of the co-expression of carbonic anhydrase IX and vascular endothelial growth factor in patients with clear cell renal cell carcinoma. Oncol. Rep. 20(3), 525-530 (2008
    • (2008) Oncol. Rep , vol.20 , Issue.3 , pp. 525-530
    • Phuoc, N.B.1    Ehara, H.2    Gotoh, T.3
  • 35
    • 75349092529 scopus 로고    scopus 로고
    • Quantification of carbonic anhydrase IX expression in serum and tissue of renal cell carcinoma patients using enzyme-linked immunosorbent assay: Prognostic and diagnostic potentials
    • Zhou GX, Ireland J, Rayman P, Finke J, Zhou M. Quantification of carbonic anhydrase IX expression in serum and tissue of renal cell carcinoma patients using enzyme-linked immunosorbent assay: prognostic and diagnostic potentials. Urology 75(2), 257-221 (2010
    • (2010) Urology , vol.75 , Issue.2 , pp. 257-221
    • Zhou, G.X.1    Ireland, J.2    Rayman, P.3    Finke, J.4    Zhou, M.5
  • 36
    • 20244386849 scopus 로고    scopus 로고
    • Using tumor markers to predict the survival of patients with metastatic renal cell carcinoma
    • Kim HL, Seligson D, Liu X et al. Using tumor markers to predict the survival of patients with metastatic renal cell carcinoma. J. Urol. 173, 1496-1501 (2005
    • (2005) J. Urol , vol.173 , pp. 1496-1501
    • Kim, H.L.1    Seligson, D.2    Liu, X.3
  • 37
    • 4143060340 scopus 로고    scopus 로고
    • Using protein expressions to predict survival in clear cell renal carcinoma
    • Kim HL, Seligson D, Liu X et al. Using protein expressions to predict survival in clear cell renal carcinoma. Clin. Cancer Res. 10, 5464-5471 (2004
    • (2004) Clin. Cancer Res , vol.10 , pp. 5464-5471
    • Kim, H.L.1    Seligson, D.2    Liu, X.3
  • 38
    • 17544404888 scopus 로고    scopus 로고
    • Targeting of renal cell carcinoma with iodine-131-labeled chimeric monoclonal antibody G250
    • Steffens MG, Boerman OC, Oosterwijk-Wakka JC et al. Targeting of renal cell carcinoma with iodine-131-labeled chimeric monoclonal antibody G250. J. Clin. Oncol. 15, 1529-1537 (1997
    • (1997) J. Clin. Oncol , vol.15 , pp. 1529-1537
    • Steffens, M.G.1    Boerman, O.C.2    Oosterwijk-Wakka, J.C.3
  • 39
    • 0032694512 scopus 로고    scopus 로고
    • Phase i radioimmunotherapy of metastatic renal cell carcinoma with 131I-labeled chimeric monoclonal antibody G250
    • Steffens MG, Boerman OC, De Mulder PH et al. Phase I radioimmunotherapy of metastatic renal cell carcinoma with 131I-labeled chimeric monoclonal antibody G250. Clin. Cancer Res. 5, 3268-3274 (1999
    • (1999) Clin. Cancer Res , vol.5 , pp. 3268-3274
    • Steffens, M.G.1    Boerman, O.C.2    De Mulder, P.H.3
  • 40
    • 0022502868 scopus 로고
    • Monoclonal antibody G 250 recognizes a determinant present in renal-cell carcinoma and absent from normal kidney
    • Oosterwijk E, Ruiter DJ, Hoedemaeker PJ et al. Monoclonal antibody G 250 recognizes a determinant present in renal-cell carcinoma and absent from normal kidney. Int. J. Cancer 38, 489-494 (1986
    • (1986) Int. J. Cancer , vol.38 , pp. 489-494
    • Oosterwijk, E.1    Ruiter, D.J.2    Hoedemaeker, P.J.3
  • 42
    • 0141568092 scopus 로고    scopus 로고
    • Targeting of metastatic renal cell carcinoma with the chimeric monoclonal antibody G250 labeled with 131)I or 111) In: An intrapatient comparison
    • Brouwers AH, Buijs WC, Oosterwijk E et al. Targeting of metastatic renal cell carcinoma with the chimeric monoclonal antibody G250 labeled with (131)I or (111) In: An intrapatient comparison. Clin. Cancer Res. 9, 3953-3960 (2003
    • (2003) Clin. Cancer Res. 9 , pp. 3953-3960
    • Brouwers, A.H.1    Buijs, W.C.2    Oosterwijk, E.3
  • 44
    • 33947504376 scopus 로고    scopus 로고
    • Preoperative characterisation of clear-cell renal carcinoma using iodine-124-labelled antibody chimeric G250 (124I-cG250) and PET in patients with renal masses: A Phase i trial
    • Divgi CR, Pandit-Taskar N, Jungbluth AA et al. Preoperative characterisation of clear-cell renal carcinoma using iodine-124-labelled antibody chimeric G250 (124I-cG250) and PET in patients with renal masses: A Phase I trial. Lancet Oncol. 8, 304-310 (2007
    • (2007) Lancet Oncol , vol.8 , pp. 304-310
    • Divgi, C.R.1    Pandit-Taskar, N.2    Jungbluth, A.A.3
  • 45
    • 84872511470 scopus 로고    scopus 로고
    • Positron emission tomography/computed tomography identification of clear cell renal cell carcinoma: Results from the REDECT trial
    • Divgi CR, Uzzo RG, Gatsonis C et al. Positron emission tomography/computed tomography identification of clear cell renal cell carcinoma: Results from the REDECT trial. J. Clin. Oncol. 31(2), 187-194 (2013
    • (2013) J. Clin. Oncol , vol.31 , Issue.2 , pp. 187-194
    • Divgi, C.R.1    Uzzo, R.G.2    Gatsonis, C.3
  • 47
    • 34548083337 scopus 로고    scopus 로고
    • A Phase i multiple dose, dose escalation study of cG250 monoclonal antibody in patients with advanced renal cell carcinoma
    • Davis I, Wiseman G, Fook-Thean Lee FT et al. A Phase I multiple dose, dose escalation study of cG250 monoclonal antibody in patients with advanced renal cell carcinoma. Cancer Immun. 7, 13-21 (2007
    • (2007) Cancer Immun , vol.7 , pp. 13-21
    • Davis, I.1    Wiseman, G.2    Fook-Thean Lee, F.T.3
  • 48
    • 11144354471 scopus 로고    scopus 로고
    • A Phase II trial of chimeric monoclonal antibody G250 for advanced renal cell carcinoma patients
    • Bleumer I, Knuth A, Oosterwijk E et al. A Phase II trial of chimeric monoclonal antibody G250 for advanced renal cell carcinoma patients. Br. J. Cancer. 90(5), 985-990 (2004
    • (2004) Br. J. Cancer , vol.90 , Issue.5 , pp. 985-990
    • Bleumer, I.1    Knuth, A.2    Oosterwijk, E.3
  • 49
    • 84888227525 scopus 로고    scopus 로고
    • ARISER: A randomized double blind Phase III study to evaluate adjuvant cG250 treatment versus placebo in patients with high-risk ccRCC-results and implications for adjuvant clinical trials
    • Suppl Abstr
    • Belldegrun A, Chamie K, Kloepfer P et al. ARISER: A randomized double blind Phase III study to evaluate adjuvant cG250 treatment versus placebo in patients with high-risk ccRCC-results and implications for adjuvant clinical trials. J. Clin. Oncol. 31(Suppl.) Abstr 4507 (2013
    • (2013) J. Clin. Oncol. , vol.31 , pp. 4507
    • Belldegrun, A.1    Chamie, K.2    Kloepfer, P.3
  • 50
    • 29144503225 scopus 로고    scopus 로고
    • A clinical trial with chimeric monoclonal antibody WX-G250 and low dose interleukin-2 pulsing scheme for advanced renal cell carcinoma
    • Bleumer I, Oosterwijk E, Oosterwijk-Wakka JC et al. A clinical trial with chimeric monoclonal antibody WX-G250 and low dose interleukin-2 pulsing scheme for advanced renal cell carcinoma. J. Urol. 175(1), 57-62 (2006
    • (2006) J. Urol , vol.175 , Issue.1 , pp. 57-62
    • Bleumer, I.1    Oosterwijk, E.2    Oosterwijk-Wakka, J.C.3
  • 51
    • 27244448455 scopus 로고    scopus 로고
    • Lack of efficacy of two consecutive treatments of radioimmunotherapy with 131IcG250 in patients with metastasized clear cell renal cell carcinoma
    • Brouwers AH, Mulders PF, De Mulder PH et al. Lack of efficacy of two consecutive treatments of radioimmunotherapy with 131IcG250 in patients with metastasized clear cell renal cell carcinoma. J. Clin. Oncol. 23, 6540-6548 (2005
    • (2005) J. Clin. Oncol , vol.23 , pp. 6540-6548
    • Brouwers, A.H.1    Mulders, P.F.2    De Mulder, P.H.3
  • 52
    • 1542399581 scopus 로고    scopus 로고
    • Optimization of radioimmunotherapy of renal cell carcinoma: Labeling of monoclonal antibody cG250 with 131I, 90Y, 177Lu, or 186Re
    • Brouwers AH, Van Eerd JE, Frielink C et al. Optimization of radioimmunotherapy of renal cell carcinoma: labeling of monoclonal antibody cG250 with 131I, 90Y, 177Lu, or 186Re. J. Nucl. Med. 45, 327-337 (2004
    • (2004) J. Nucl. Med , vol.45 , pp. 327-337
    • Brouwers, A.H.1    Van Eerd, J.E.2    Frielink, C.3
  • 53
    • 84881186900 scopus 로고    scopus 로고
    • Phase 1 radioimmunotherapy study with lutetium 177-labelled anti-carbonic anhydrase IX monoclonal antibody girentuximab in patients with advanced renal cell carcinoma
    • Stillebroer A, Boerman O, Desar I et al. Phase 1 radioimmunotherapy study with lutetium 177-labelled anti-carbonic anhydrase IX monoclonal antibody girentuximab in patients with advanced renal cell carcinoma. Eur. Urol. 64, 478-485 (2013
    • (2013) Eur. Urol , vol.64 , pp. 478-485
    • Stillebroer, A.1    Boerman, O.2    Desar, I.3
  • 55
    • 33645697721 scopus 로고    scopus 로고
    • A Phase i trial of vaccination of CA9-derived peptides for HLA-A24-positive patients with cytokine refractory metastatic renal cell carcinoma
    • Uemura H, Fujimoto K, Tanaka M et al. A Phase I trial of vaccination of CA9-derived peptides for HLA-A24-positive patients with cytokine refractory metastatic renal cell carcinoma. Clin. Cancer Res. 12, 1768-1775 (2006
    • (2006) Clin. Cancer Res , vol.12 , pp. 1768-1775
    • Uemura, H.1    Fujimoto, K.2    Tanaka, M.3
  • 56
    • 84923193781 scopus 로고    scopus 로고
    • Hypoxia-induced carbonic anhydrase IX as a target for cancer therapy: From biology to clinical use
    • Pastorek J, Pastorekova S. Hypoxia-induced carbonic anhydrase IX as a target for cancer therapy: from biology to clinical use. Semin. Cancer Biol. 31, 52-64 (2015
    • (2015) Semin. Cancer Biol , vol.31 , pp. 52-64
    • Pastorek, J.1    Pastorekova, S.2
  • 57
    • 0035503010 scopus 로고    scopus 로고
    • Induction of G250-targeted and T-cell-mediated antitumor activity against renal cell carcinoma using a chimeric fusion protein consisting of G250 and granulocyte/ monocyte-colony stimulating factor
    • Tso CL, Zisman A, Pantuck A et al. Induction of G250-targeted and T-cell-mediated antitumor activity against renal cell carcinoma using a chimeric fusion protein consisting of G250 and granulocyte/ monocyte-colony stimulating factor. Cancer Res. 61, 7925-7933 (2001
    • (2001) Cancer Res , vol.61 , pp. 7925-7933
    • Tso, C.L.1    Zisman, A.2    Pantuck, A.3
  • 58
    • 10744230408 scopus 로고    scopus 로고
    • Novel kidney cancer immunotherapy based on the granulocyte-macrophage colony-stimulating factor and carbonic anhydrase IX fusion gene
    • Hernandez JM, Bui MH, Han KR et al. Novel kidney cancer immunotherapy based on the granulocyte-macrophage colony-stimulating factor and carbonic anhydrase IX fusion gene. Clin. Cancer Res. 9, 1906-1916 (2003)
    • (2003) Clin. Cancer Res , vol.9 , pp. 1906-1916
    • Hernandez, J.M.1    Bui, M.H.2    Han, K.R.3
  • 60
    • 66149113671 scopus 로고    scopus 로고
    • Targeted therapy of renal cell carcinoma: Synergistic activity of cG250-TNF and IFNg
    • Bauer S, Oosterwijk-Wakka JC, Adrian N et al. Targeted therapy of renal cell carcinoma: synergistic activity of cG250-TNF and IFNg. Int. J. Cancer 125, 115-123 (2009
    • (2009) Int. J. Cancer , vol.125 , pp. 115-123
    • Bauer, S.1    Oosterwijk-Wakka, J.C.2    Adrian, N.3
  • 61
    • 84905240545 scopus 로고    scopus 로고
    • Expression of hypoxia-inducible factor-1α predicts benefit from hypoxia modification in invasive bladder cancer
    • Hunter BA, Eustace A, Irlam JJ et al. Expression of hypoxia-inducible factor-1α predicts benefit from hypoxia modification in invasive bladder cancer. Br. J. Cancer. 111(3), 437-443 (2014
    • (2014) Br. J. Cancer , vol.111 , Issue.3 , pp. 437-443
    • Hunter, B.A.1    Eustace, A.2    Irlam, J.J.3
  • 62
    • 0034671307 scopus 로고    scopus 로고
    • Hypoxia-inducible expression of tumor-associated carbonic anhydrases
    • Wykoff CC, Beasley NJ, Watson PH et al. Hypoxia-inducible expression of tumor-associated carbonic anhydrases. Cancer Res. 60, 7075-7083 (2000)
    • (2000) Cancer Res , vol.60 , pp. 7075-7083
    • Wykoff, C.C.1    Beasley, N.J.2    Watson, P.H.3
  • 63
    • 12344260056 scopus 로고    scopus 로고
    • Carbonic anhydrase IX, a marker of hypoxia: Correlation with clinical outcome in transitional cell carcinoma of the bladder
    • Hussain SA, Palmer DH, Ganesan R et al. Carbonic anhydrase IX, a marker of hypoxia: correlation with clinical outcome in transitional cell carcinoma of the bladder. Oncol. Rep. 11(5), 1005-1010 (2004
    • (2004) Oncol. Rep , vol.11 , Issue.5 , pp. 1005-1010
    • Hussain, S.A.1    Palmer, D.H.2    Ganesan, R.3
  • 64
    • 0242298213 scopus 로고    scopus 로고
    • GLUT1 and CAIX as intrinsic markers of hypoxia in bladder cancer: Relationship with vascularity and proliferation as predictors of outcome of ARCON
    • Hoskin PJ, Sibtain A, Daley FM, Wilson GD. GLUT1 and CAIX as intrinsic markers of hypoxia in bladder cancer: relationship with vascularity and proliferation as predictors of outcome of ARCON. Br. J. Cancer. 89, 1290-1297 (2003
    • (2003) Br. J. Cancer , vol.89 , pp. 1290-1297
    • Hoskin, P.J.1    Sibtain, A.2    Daley, F.M.3    Wilson, G.D.4
  • 65
    • 63449135054 scopus 로고    scopus 로고
    • Carbonic anhydrase IX in bladder cancer: A diagnostic, prognostic, and therapeutic molecular marker
    • Klatte T, Seligson DB, Rao JY et al. Carbonic anhydrase IX in bladder cancer: A diagnostic, prognostic, and therapeutic molecular marker. Cancer 115(7): 1448-1458 (2009
    • (2009) Cancer , vol.115 , Issue.7 , pp. 1448-1458
    • Klatte, T.1    Seligson, D.B.2    Rao, J.Y.3
  • 66
    • 0037156961 scopus 로고    scopus 로고
    • The hypoxia-inducible genes VEGF and CA9 are differentially regulated in superficial vs invasive bladder cancer
    • Turner KJ, Crew JP, Wykoff CC et al. The hypoxia-inducible genes VEGF and CA9 are differentially regulated in superficial vs invasive bladder cancer. Br. J. Cancer. 86, 1276-1282 (2002
    • (2002) Br. J. Cancer , vol.86 , pp. 1276-1282
    • Turner, K.J.1    Crew, J.P.2    Wykoff, C.C.3
  • 67
    • 0023547004 scopus 로고
    • Monoclonal antibodies to a new antigenic marker in epithelial prostatic cells and serum of prostatic cancer patients
    • Horoszewicz JS, Kawinski E, Murphy GP. Monoclonal antibodies to a new antigenic marker in epithelial prostatic cells and serum of prostatic cancer patients. AntiCancer Res. 7, 927-936 (1987
    • (1987) AntiCancer Res , vol.7 , pp. 927-936
    • Horoszewicz, J.S.1    Kawinski, E.2    Murphy, G.P.3
  • 68
    • 0027500319 scopus 로고
    • Molecular cloning of a complementary DNA encoding prostate-specific membrane antigen
    • Israeli RS, Powell CT, Fair WR, Heston WD. Molecular cloning of a complementary DNA encoding prostate-specific membrane antigen. Cancer Res. 53, 227-230 (1993
    • (1993) Cancer Res , vol.53 , pp. 227-230
    • Israeli, R.S.1    Powell, C.T.2    Fair, W.R.3    Heston, W.D.4
  • 69
    • 0032104284 scopus 로고    scopus 로고
    • Prostate specific membrane antigen expression in prostatic intraepithelial neoplasia and adenocarcinoma: Study of 184 cases
    • Bostwick DG, Pacelli A, Blute M et al. Prostate specific membrane antigen expression in prostatic intraepithelial neoplasia and adenocarcinoma: study of 184 cases. Cancer 82, 2256-2261 (1998
    • (1998) Cancer , vol.82 , pp. 2256-2261
    • Bostwick, D.G.1    Pacelli, A.2    Blute, M.3
  • 70
    • 0031042591 scopus 로고    scopus 로고
    • Prostate-specific membrane antigen expression in normal and malignant human tissues
    • Silver DA, Pellicer I, Fair WR et al. Prostate-specific membrane antigen expression in normal and malignant human tissues. Clin. Cancer Res. 3, 81-85 (1997
    • (1997) Clin. Cancer Res , vol.3 , pp. 81-85
    • Silver, D.A.1    Pellicer, I.2    Fair, W.R.3
  • 71
    • 0030219893 scopus 로고    scopus 로고
    • Up regulation of prostate-specific membrane antigen after androgen-deprivation therapy
    • Wright GL Jr, Grob BM, Haley C et al. Up regulation of prostate-specific membrane antigen after androgen-deprivation therapy. Urology 48, 326-334 (1996
    • (1996) Urology , vol.48 , pp. 326-334
    • Wright, G.L.1    Grob, B.M.2    Haley, C.3
  • 72
    • 0030046044 scopus 로고    scopus 로고
    • Prostate-specific membrane antigen is a hydrolase with substrate and pharmacologic characteristics of a neuropeptidase
    • Carter RE, Feldman AR, Coyle JT. Prostate-specific membrane antigen is a hydrolase with substrate and pharmacologic characteristics of a neuropeptidase. Proc. Natl Acad. Sci. USA 93, 749-753 (1996
    • (1996) Proc. Natl Acad. Sci. USA , vol.93 , pp. 749-753
    • Carter, R.E.1    Feldman, A.R.2    Coyle, J.T.3
  • 73
    • 0033560036 scopus 로고    scopus 로고
    • Characterization of the enzymatic activity of PSM: Comparison with brain NAALADase
    • Tiffany CW, Lapidus RG, Merion A, Calvin DC, Slusher BS. Characterization of the enzymatic activity of PSM: comparison with brain NAALADase. Prostate 39, 28-35 (1999
    • (1999) Prostate , vol.39 , pp. 28-35
    • Tiffany, C.W.1    Lapidus, R.G.2    Merion, A.3    Calvin, D.C.4    Slusher, B.S.5
  • 74
    • 0034703861 scopus 로고    scopus 로고
    • Glutamate carboxypeptidase II: A polymorphism associated with lower levels of serum folate and hyperhomocysteinemia
    • Devlin AM, Ling EH, Peerson JM et al. Glutamate carboxypeptidase II: A polymorphism associated with lower levels of serum folate and hyperhomocysteinemia. Hum. Mol. Genet. 9, 2837-2844 (2009
    • (2009) Hum. Mol. Genet , vol.9 , pp. 2837-2844
    • Devlin, A.M.1    Ling, E.H.2    Peerson, J.M.3
  • 75
    • 84864281271 scopus 로고    scopus 로고
    • The prostate specific membrane antigen regulates the expression of IL-6 and CCL5 in prostate tumour cells by activating the MAPK pathways
    • Colombatti M, Grasso S, Porzia A et al. The prostate specific membrane antigen regulates the expression of IL-6 and CCL5 in prostate tumour cells by activating the MAPK pathways. PLoS ONE 4(2), 4608 (2009
    • (2009) PLoS ONE , vol.4 , Issue.2 , pp. 4608
    • Colombatti, M.1    Grasso, S.2    Porzia, A.3
  • 76
    • 0033168844 scopus 로고    scopus 로고
    • Five different anti-prostate-specific membrane antigen (PSMA) antibodies confirm PSMA expression in tumor-associated neovasculature
    • Chang SS, Reuter VE, Heston WD, Bander NH, Grauer LS, Gaudin PB. Five different anti-prostate-specific membrane antigen (PSMA) antibodies confirm PSMA expression in tumor-associated neovasculature. Cancer Res. 59, 3192-3198 (1999
    • (1999) Cancer Res , vol.59 , pp. 3192-3198
    • Chang, S.S.1    Reuter, V.E.2    Heston, W.D.3    Bander, N.H.4    Grauer, L.S.5    Gaudin, P.B.6
  • 77
    • 33745845906 scopus 로고    scopus 로고
    • Prostate-specific membrane antigen regulates angiogenesis by modulating integrin signal transduction
    • Conway RE, Petrovic N, Li Z, Heston W, Wu D, Shapiro LH. Prostate-specific membrane antigen regulates angiogenesis by modulating integrin signal transduction. Mol. Cell Biol. 26(14), 5310-5324 (2006
    • (2006) Mol. Cell Biol , vol.26 , Issue.14 , pp. 5310-5324
    • Conway, R.E.1    Petrovic, N.2    Li, Z.3    Heston, W.4    Wu, D.5    Shapiro, L.H.6
  • 78
    • 84864007957 scopus 로고    scopus 로고
    • Prostate specific membrane antigen (PSMA) regulates angiogenesis independently of VEGF during ocular neovascularization
    • Grant CL, Caromile LA, Ho V, Durrani K, Rahman MM, Claffey KP, Fong GH, Shapiro LH. Prostate specific membrane antigen (PSMA) regulates angiogenesis independently of VEGF during ocular neovascularization. PLoS ONE 7(7), e41285 (2012
    • (2012) PLoS ONE , vol.7 , Issue.7 , pp. e41285
    • Grant, C.L.1    Caromile, L.A.2    Ho, V.3    Durrani, K.4    Rahman, M.M.5    Claffey, K.P.6    Fong, G.H.7    Shapiro, L.H.8
  • 79
    • 79959579512 scopus 로고    scopus 로고
    • Role of TMPRSS2-ERG gene fusion in negative regulation of PSMA expression
    • Yin L, Rao P, Elson P et al. Role of TMPRSS2-ERG gene fusion in negative regulation of PSMA expression. PLoS ONE 6(6), e21319 (2011
    • (2011) PLoS ONE , vol.6 , Issue.6 , pp. e21319
    • Yin, L.1    Rao, P.2    Elson, P.3
  • 80
    • 0030940108 scopus 로고    scopus 로고
    • Location of prostate-specific membrane antigen in the LNCaP prostate carcinoma cell line
    • Troyer JK, Beckett ML, Wright GL. Location of prostate-specific membrane antigen in the LNCaP prostate carcinoma cell line. Prostate 30, 232-234 (1997
    • (1997) Prostate , vol.30 , pp. 232-234
    • Troyer, J.K.1    Beckett, M.L.2    Wright, G.L.3
  • 81
    • 0029158260 scopus 로고
    • Biochemical characterization and mapping of the 7E11-5.3 epitope of the prostate specific membrane antigen
    • Troyer JK, Feng Q, Beckett ML, Wright GL. Biochemical characterization and mapping of the 7E11-5.3 epitope of the prostate specific membrane antigen. Urol. Oncol. 1, 29-37 (1995
    • (1995) Urol. Oncol , vol.1 , pp. 29-37
    • Troyer, J.K.1    Feng, Q.2    Beckett, M.L.3    Wright, G.L.4
  • 82
    • 0034665171 scopus 로고    scopus 로고
    • In vitro characterization of radiolabeledmonoclonal antibodies specific for the extracellular domain of prostate specific membrane antigen
    • Smith-Jones PM, Vallabahajosula S, Goldsmith SJ et al. In vitro characterization of radiolabeledmonoclonal antibodies specific for the extracellular domain of prostate specific membrane antigen. Cancer Res. 60, 5237-5243 (2000
    • (2000) Cancer Res , vol.60 , pp. 5237-5243
    • Smith-Jones, P.M.1    Vallabahajosula, S.2    Goldsmith, S.J.3
  • 83
    • 0141919750 scopus 로고    scopus 로고
    • Targeting metastatic prostate cancer with radiolabeled monoclonal antibody J591 to the extracellular domain of prostate specific membrane antigen
    • Bander NH, Trabulsi EJ, Kostakoglu L et al. Targeting metastatic prostate cancer with radiolabeled monoclonal antibody J591 to the extracellular domain of prostate specific membrane antigen. J. Urol. 170, 1717-1721 (2003
    • (2003) J. Urol , vol.170 , pp. 1717-1721
    • Bander, N.H.1    Trabulsi, E.J.2    Kostakoglu, L.3
  • 84
    • 0032530135 scopus 로고    scopus 로고
    • Constitutive and antibody-induced internalization of prostatespecific membrane antigen
    • Liu H, Rajasekaran AK, Moy P et al. Constitutive and antibody-induced internalization of prostatespecific membrane antigen. Cancer Res. 58, 4055-4060 (1998
    • (1998) Cancer Res , vol.58 , pp. 4055-4060
    • Liu, H.1    Rajasekaran, A.K.2    Moy, P.3
  • 86
    • 22044451179 scopus 로고    scopus 로고
    • Phase i trial of 177Lutetium-labeled J591, a monoclonal antibody to prostate specific membrane antigen, in patients with androgen-independent prostate cancer
    • Bander NH, Milowsky MI, Nanus DM, Kostakoglu L, Vallabhajosula S, Goldsmith SJ. Phase I trial of 177Lutetium-labeled J591, a monoclonal antibody to prostate specific membrane antigen, in patients with androgen-independent prostate cancer. J. Clin. Oncol. 23, 4591-4601 (2005
    • (2005) J. Clin. Oncol , vol.23 , pp. 4591-4601
    • Bander, N.H.1    Milowsky, M.I.2    Nanus, D.M.3    Kostakoglu, L.4    Vallabhajosula, S.5    Goldsmith, S.J.6
  • 87
    • 84884536175 scopus 로고    scopus 로고
    • Phase II study of Lutetium-177-labeled anti-prostate-specific membrane antigen monoclonal antibody J591 for metastatic castration-resistant prostate cancer
    • Tagawa ST, Milowsky MI, Morris M et al. Phase II study of Lutetium-177-labeled anti-prostate-specific membrane antigen monoclonal antibody J591 for metastatic castration-resistant prostate cancer. Clin. Cancer Res. 19(18), 5182-5191 (2013
    • (2013) Clin. Cancer Res , vol.19 , Issue.18 , pp. 5182-5191
    • Tagawa, S.T.1    Milowsky, M.I.2    Morris, M.3
  • 88
    • 84919950141 scopus 로고    scopus 로고
    • 89Zr-huJ591 immuno-PET imaging in patients with advanced metastatic prostate cancer
    • Pandit-Taskar N, O'Donoghue JA, Beylergil V et al. 89Zr-huJ591 immuno-PET imaging in patients with advanced metastatic prostate cancer. Eur. J. Nucl. Med. Mol. Imaging 41, 2093-2105 (2014
    • (2014) Eur. J. Nucl. Med. Mol. Imaging , vol.41 , pp. 2093-2105
    • Pandit-Taskar, N.1    O'Donoghue, J.A.2    Beylergil, V.3
  • 89
    • 4143084967 scopus 로고    scopus 로고
    • Anti-prostate specific membrane antigen designer T cells for prostate cancer therapy
    • Ma Q, Safar M, Holmes E, Wang Y, Boynton AL, Junghans RP. Anti-prostate specific membrane antigen designer T cells for prostate cancer therapy. Prostate 61(1), 12-25 (2004
    • (2004) Prostate , vol.61 , Issue.1 , pp. 12-25
    • Ma, Q.1    Safar, M.2    Holmes, E.3    Wang, Y.4    Boynton, A.L.5    Junghans, R.P.6
  • 90
    • 84871360414 scopus 로고    scopus 로고
    • Regression of human prostate cancer xenografts in mice by AMG 212/BAY 2010112, a novel PSMA/CD3-Bispecific BiTE antibody cross-reactive with non-human primate antigens
    • Friedrich M, Raum T, Lutterbuese R et al. Regression of human prostate cancer xenografts in mice by AMG 212/BAY 2010112, a novel PSMA/CD3-Bispecific BiTE antibody cross-reactive with non-human primate antigens. Mol. Cancer Ther. 11(12), 2664-2673 (2012
    • (2012) Mol. Cancer Ther , vol.11 , Issue.12 , pp. 2664-2673
    • Friedrich, M.1    Raum, T.2    Lutterbuese, R.3
  • 91
    • 80052688423 scopus 로고    scopus 로고
    • Prostate-specific membrane antigen antibody-drug conjugate (PSMA ADC): A Phase i trial in taxane-refractory prostate cancer
    • Abst 4650
    • Petrylak DP, Kantoff PW, Frank RC et al. Prostate-specific membrane antigen antibody-drug conjugate (PSMA ADC): A Phase I trial in taxane-refractory prostate cancer. J. Clin. Oncol. 29(5), Abst 4650 (2011
    • (2011) J. Clin. Oncol , vol.29 , Issue.5
    • Petrylak, D.P.1    Kantoff, P.W.2    Frank, R.C.3
  • 92
    • 84920723640 scopus 로고    scopus 로고
    • A Phase II trial of prostate-specific membrane antigen antibody drug conjugate (PSMA ADC) in taxane-refractory metastatic castration-resistant prostate cancer (mCRPC
    • Abstract 83
    • Petrylak DP, Smith DC, Appleman LJ et al. A Phase II trial of prostate-specific membrane antigen antibody drug conjugate (PSMA ADC) in taxane-refractory metastatic castration-resistant prostate cancer (mCRPC). J. Clin. Oncol. 32(4), Abstract 83 (2014
    • (2014) J. Clin. Oncol , vol.32 , Issue.4
    • Petrylak, D.P.1    Smith, D.C.2    Appleman, L.J.3
  • 93
    • 84965184547 scopus 로고    scopus 로고
    • Noninvasive imaging of PSMA in prostate tumors with 89Zr-Labeled huJ591 engineered antibody fragments: The faster alternatives
    • Viola-Villegas NT, Sevak KK, Carlin SD et al. Noninvasive imaging of PSMA in prostate tumors with 89Zr-Labeled huJ591 engineered antibody fragments: the faster alternatives. Mol. Pharm. 11(11), 3965-3973 (2014
    • (2014) Mol. Pharm , vol.11 , Issue.11 , pp. 3965-3973
    • Viola-Villegas, N.T.1    Sevak, K.K.2    Carlin, S.D.3
  • 94
    • 0030053446 scopus 로고    scopus 로고
    • Design, syn
    • thesis, and biological activity of a potent inhibitor of the neuropeptidase N-acetylated alpha-linked acidic dipeptidase
    • Jackson PF, Cole DC, Slusher BS et al. Design, synthesis, and biological activity of a potent inhibitor of the neuropeptidase N-acetylated alpha-linked acidic dipeptidase. J. Med. Chem. 39, 619-622 (1996
    • (1996) J. Med. Chem , vol.39 , pp. 619-622
    • Jackson, P.F.1    Cole, D.C.2    Slusher, B.S.3
  • 95
    • 0035254655 scopus 로고    scopus 로고
    • Design of remarkably simple, yet potent urea-based inhibitors of glutamate carboxypeptidase II (NALADase
    • Kozikowski AP, Nan F, Conti P et al. Design of remarkably simple, yet potent urea-based inhibitors of glutamate carboxypeptidase II (NALADase). J. Med. Chem. 44, 298-301 (2001
    • (2001) J. Med. Chem , vol.44 , pp. 298-301
    • Kozikowski, A.P.1    Nan, F.2    Conti, P.3
  • 96
    • 20344374435 scopus 로고    scopus 로고
    • Radiolabeled small molecule ligands for prostate-specific membrane antigen: In vivo imaging in experimental models of prostate cancer
    • Foss CA, Mease RC, Fan H et al. Radiolabeled small molecule ligands for prostate-specific membrane antigen: in vivo imaging in experimental models of prostate cancer. Clin. Cancer Res. 11, 4022-402 (2005
    • (2005) Clin. Cancer Res , vol.11 , pp. 4022-4402
    • Foss, C.A.1    Mease, R.C.2    Fan, H.3
  • 97
    • 84870340190 scopus 로고    scopus 로고
    • Biodistribution, tumor detection, and radiation dosimetry of 18F-DCFBC, a low-molecular-weight inhibitor of prostate-specific membrane antigen, in patients with metastatic prostate cancer
    • Cho SY, Gage KL, Mease RC et al. Biodistribution, tumor detection, and radiation dosimetry of 18F-DCFBC, a low-molecular-weight inhibitor of prostate-specific membrane antigen, in patients with metastatic prostate cancer. J. Nucl. Med. 53(12), 1883-1891 (2012
    • (2012) J. Nucl. Med , vol.53 , Issue.12 , pp. 1883-1891
    • Cho, S.Y.1    Gage, K.L.2    Mease, R.C.3
  • 98
    • 60549117368 scopus 로고    scopus 로고
    • A series of halogenated heterodimeric inhibitors of prostatespecific membrane antigen (PSMA) as radiolabeled probes for targeting prostate cancer
    • Maresca KP, Hillier SM, Femia FJ et al. A series of halogenated heterodimeric inhibitors of prostatespecific membrane antigen (PSMA) as radiolabeled probes for targeting prostate cancer. J. Med. Chem 52, 347-357 (2009
    • (2009) J. Med. Chem , vol.52 , pp. 347-357
    • Maresca, K.P.1    Hillier, S.M.2    Femia, F.J.3
  • 99
    • 70149094319 scopus 로고    scopus 로고
    • Preclinical evaluation of novel glutamate-urea-lysine analogues that target prostate-specific membrane antigen as molecular imaging pharmaceuticals for prostate cancer
    • Hillier SM, Maresca KP, Femia FJ et al. Preclinical evaluation of novel glutamate-urea-lysine analogues that target prostate-specific membrane antigen as molecular imaging pharmaceuticals for prostate cancer. Cancer Res. 69(17), 6932-6940 (2009
    • (2009) Cancer Res , vol.69 , Issue.17 , pp. 6932-6940
    • Hillier, S.M.1    Maresca, K.P.2    Femia, F.J.3
  • 100
    • 84874820819 scopus 로고    scopus 로고
    • First-in-man evaluation of two high-affinity PSMA-avid small molecules for imaging prostate cancer
    • Barrett JA, Coleman RE, Goldsmith SJ et al. First-in-man evaluation of two high-affinity PSMA-avid small molecules for imaging prostate cancer. J. Nucl. Med. 54(3), 380-387 (2013
    • (2013) J. Nucl. Med , vol.54 , Issue.3 , pp. 380-387
    • Barrett, J.A.1    Coleman, R.E.2    Goldsmith, S.J.3
  • 101
    • 79960301987 scopus 로고    scopus 로고
    • 123I-MIP-1072, a small-molecule inhibitor of prostate-specific membrane antigen, is effective at monitoring tumor response to taxane therapy
    • Hillier SM, Kern AM, Maresca KP et al. 123I-MIP-1072, a small-molecule inhibitor of prostate-specific membrane antigen, is effective at monitoring tumor response to taxane therapy. J. Nucl. Med. 52, 1087-1093 (2011
    • (2011) J. Nucl. Med , vol.52 , pp. 1087-1093
    • Hillier, S.M.1    Kern, A.M.2    Maresca, K.P.3
  • 102
    • 84910675926 scopus 로고    scopus 로고
    • 99mTc-labeled small-molecule inhibitors of prostate-specific membrane antigen: Pharmacokinetics and biodistribution studies in healthy subjects and patients with metastatic prostate cancer
    • Vallabhajosula S, Nikolopoulou A, Babich JW et al. 99mTc-labeled small-molecule inhibitors of prostate-specific membrane antigen: pharmacokinetics and biodistribution studies in healthy subjects and patients with metastatic prostate cancer. J. Nucl. Med. 55, 1-8 (2014
    • (2014) J. Nucl. Med , vol.55 , pp. 1-8
    • Vallabhajosula, S.1    Nikolopoulou, A.2    Babich, J.W.3
  • 104
    • 84903709596 scopus 로고    scopus 로고
    • Radiation dosimetry and first therapy results with a 124)I/ (131)I-labeled small molecule (MIP-1095) targeting PSMA for prostate cancer therapy
    • Zechmann CM, Afshar-Oromieh A, Armor T et al. Radiation dosimetry and first therapy results with a (124)I/ (131)I-labeled small molecule (MIP-1095) targeting PSMA for prostate cancer therapy. Eur. J. Nucl. Med. Mol. Imaging 41(7), 1280-1292 (2014
    • (2014) Eur. J. Nucl. Med. Mol. Imaging , vol.41 , Issue.7 , pp. 1280-1292
    • Zechmann, C.M.1    Afshar-Oromieh, A.2    Armor, T.3
  • 105
    • 84859991899 scopus 로고    scopus 로고
    • 68Ga-complex lipophilicity and the targeting property of a urea-based PSMA inhibitor for PET imaging
    • Eder M, Schäfer M, Bauder-Wüst U et al. 68Ga-complex lipophilicity and the targeting property of a urea-based PSMA inhibitor for PET imaging. Bioconjug. Chem. 23(4), 688-697 (2012
    • (2012) Bioconjug. Chem , vol.23 , Issue.4 , pp. 688-697
    • Eder, M.1    Schäfer, M.2    Bauder-Wüst, U.3
  • 106
    • 84903582764 scopus 로고    scopus 로고
    • Novel preclinical and radiopharmaceutical aspects of [68Ga]Ga-PSMA-HBED-CC: A new PET tracer for imaging of prostate cancer
    • Eder M, Neels O, Müller M et al. Novel preclinical and radiopharmaceutical aspects of [68Ga]Ga-PSMA-HBED-CC: A new PET tracer for imaging of prostate cancer. Pharmaceuticals (Basel) 7(7), 779-796 (2014
    • (2014) Pharmaceuticals (Basel , vol.7 , Issue.7 , pp. 779-796
    • Eder, M.1    Neels, O.2    Müller, M.3
  • 107
    • 84885381026 scopus 로고    scopus 로고
    • PET imaging with a [68)Ga]gallium-labelled PSMA ligand for the diagnosis of prostate cancer: Biodistribution in humans and first evaluation of tumour lesions
    • Afshar-Oromieh A, Malcher A, Eder M et al. PET imaging with a [(68)Ga]gallium-labelled PSMA ligand for the diagnosis of prostate cancer: biodistribution in humans and first evaluation of tumour lesions. Eur J. Nucl. Med. Mol. Imaging. 40(5), 797-798 (2013
    • (2013) Eur J. Nucl. Med. Mol. Imaging. , vol.40 , Issue.5 , pp. 797-798
    • Afshar-Oromieh, A.1    Malcher, A.2    Eder, M.3
  • 108
    • 84890590469 scopus 로고    scopus 로고
    • Comparison of PET imaging with a 68)Ga-labelled PSMA ligand and (18) F-choline-based PET/CT for the diagnosis of recurrent prostate cancer
    • Afshar-Oromieh A, Zechmann CM, Malcher A et al. Comparison of PET imaging with a (68)Ga-labelled PSMA ligand and (18) F-choline-based PET/CT for the diagnosis of recurrent prostate cancer. Eur J. Nucl. Med. Mol. Imaging. 41(1), 11-20 (2014
    • (2014) Eur J. Nucl. Med. Mol. Imaging. , vol.41 , Issue.1 , pp. 11-20
    • Afshar-Oromieh, A.1    Zechmann, C.M.2    Malcher, A.3
  • 109
    • 68949116384 scopus 로고    scopus 로고
    • Heterogeneity of prostate-specific membrane antigen (PSMA) expression in prostate carcinoma with distant metastasis
    • Mannweiler S, Amersdorfer P, Trajanoski S, Terrett JA, King D, Mehes G. Heterogeneity of prostate-specific membrane antigen (PSMA) expression in prostate carcinoma with distant metastasis. Pathol. Oncol. Res. 15(2), 167-172 (2009
    • (2009) Pathol. Oncol. Res , vol.15 , Issue.2 , pp. 167-172
    • Mannweiler, S.1    Amersdorfer, P.2    Trajanoski, S.3    Terrett, J.A.4    King, D.5    Mehes, G.6
  • 110
    • 84897021830 scopus 로고    scopus 로고
    • Preclinical evaluation of a bispecific low-molecular heterodimer targeting both PSMA and GRPR for improved PET imaging and therapy of prostate cancer
    • Eder M, Schäfer M, Bauder-Wüst U, Haberkorn U, Eisenhut M, Kopka K. Preclinical evaluation of a bispecific low-molecular heterodimer targeting both PSMA and GRPR for improved PET imaging and therapy of prostate cancer. Prostate 74(6), 659-668 (2014).
    • (2014) Prostate , vol.74 , Issue.6 , pp. 659-668
    • Eder, M.1    Schäfer, M.2    Bauder-Wüst, U.3    Haberkorn, U.4    Eisenhut, M.5    Kopka, K.6
  • 111
    • 84866645930 scopus 로고    scopus 로고
    • PSMA-targeted theranostic nanoplex for prostate cancer therapy
    • Chen Z1, Penet MF, Nimmagadda S et al. PSMA-targeted theranostic nanoplex for prostate cancer therapy. ACS Nano. 6(9), 7752-7762 (2012)
    • (2012) ACS Nano , vol.6 , Issue.9 , pp. 7752-7762
    • Chen, Z.1    Penet, M.F.2    Nimmagadda, S.3
  • 112
    • 84871286519 scopus 로고    scopus 로고
    • Restructuring G-protein-coupled receptor activation
    • Audet M, Bouvier M. Restructuring G-protein-coupled receptor activation. Cell 151(1), 14-23 (2012
    • (2012) Cell , vol.151 , Issue.1 , pp. 14-23
    • Audet, M.1    Bouvier, M.2
  • 114
    • 33748916428 scopus 로고    scopus 로고
    • Functional roles of the NTS2 and NTS3 receptors
    • Mazella J, Vincent JP. Functional roles of the NTS2 and NTS3 receptors. Peptides. 27(10), 2469-2475 (2006
    • (2006) Peptides , vol.27 , Issue.10 , pp. 2469-2475
    • Mazella, J.1    Vincent, J.P.2
  • 115
    • 84874408562 scopus 로고    scopus 로고
    • Neurotensin and its high affinity receptor 1 as a potential pharmacological target in cancer therapy
    • Wu Z, Martinez-Fong D, Trédaniel J, Forgez P. Neurotensin and its high affinity receptor 1 as a potential pharmacological target in cancer therapy. Front. Endocrinol. 3, 184 (2013
    • (2013) Front. Endocrinol , vol.3 , Issue.184
    • Wu, Z.1    Martinez-Fong, D.2    Trédaniel, J.3    Forgez, P.4
  • 116
    • 38049132623 scopus 로고    scopus 로고
    • Bombesin-related peptides and their receptors: Recent advances in their role in physiology and disease states
    • Gonzalez N, Moody TW, Igarashi H, Ito T, Jensen RT. Bombesin-related peptides and their receptors: recent advances in their role in physiology and disease states. Curr. Opin. Endocrinol. Diabetes Obes. 15(1), 58-64 (2008
    • (2008) Curr. Opin. Endocrinol. Diabetes Obes , vol.15 , Issue.1 , pp. 58-64
    • Gonzalez, N.1    Moody, T.W.2    Igarashi, H.3    Ito, T.4    Jensen, R.T.5
  • 117
    • 0033104343 scopus 로고    scopus 로고
    • Gastrin-releasing peptide receptors in the human prostate: Relation to neoplastic transformation
    • Markwalder R, Reubi JC. Gastrin-releasing peptide receptors in the human prostate: relation to neoplastic transformation. Cancer Res. 59(5), 1152-1159 (1999
    • (1999) Cancer Res , vol.59 , Issue.5 , pp. 1152-1159
    • Markwalder, R.1    Reubi, J.C.2
  • 118
    • 84855701740 scopus 로고    scopus 로고
    • Profiling gastrin-releasing peptide receptor in prostate tissues: Clinical implications and molecular correlates
    • Beer M, Montani M, Gerhardt J et al. Profiling gastrin-releasing peptide receptor in prostate tissues: clinical implications and molecular correlates. Prostate 72(3), 318-325 (2012)
    • (2012) Prostate , vol.72 , Issue.3 , pp. 318-325
    • Beer, M.1    Montani, M.2    Gerhardt, J.3
  • 119
    • 67449168058 scopus 로고    scopus 로고
    • Expression of the gastrin-releasing peptide receptor, the prostate stem cell antigen and the prostate-specific membrane antigen in lymph node and bone metastases of prostate cancer
    • Ananias HJ, Van den Heuvel MC, Helfrich W, De Jong IJ. Expression of the gastrin-releasing peptide receptor, the prostate stem cell antigen and the prostate-specific membrane antigen in lymph node and bone metastases of prostate cancer. Prostate 69(10), 1101-1108 (2009
    • (2009) Prostate , vol.69 , Issue.10 , pp. 1101-1108
    • Ananias, H.J.1    Van Den Heuvel, M.C.2    Helfrich, W.3    De Jong, I.J.4
  • 120
    • 84886427044 scopus 로고    scopus 로고
    • In vivo imaging of prostate cancer using [68Ga]-labeled bombesin analog BAY86-7548
    • Kähkönen E, Jambor I, Kemppainen J et al. In vivo imaging of prostate cancer using [68Ga]-labeled bombesin analog BAY86-7548. Clin. Cancer Res. 19(19), 5434-5443 (2013
    • (2013) Clin. Cancer Res , vol.19 , Issue.19 , pp. 5434-5443
    • Kähkönen, E.1    Jambor, I.2    Kemppainen, J.3
  • 121
    • 84902465516 scopus 로고    scopus 로고
    • Positron emission tomography (PET) imaging of prostate cancer with a gastrin releasing peptide receptor antagonist - From mice to men
    • Wieser G, Mansi R, Grosu AL et al. Positron emission tomography (PET) imaging of prostate cancer with a gastrin releasing peptide receptor antagonist - from mice to men. Theranostics 4(4), 412-419 (2014
    • (2014) Theranostics , vol.4 , Issue.4 , pp. 412-419
    • Wieser, G.1    Mansi, R.2    Grosu, A.L.3
  • 122
    • 0028290656 scopus 로고
    • Neurotensin is an autocrine trophic factor stimulated by androgen withdrawal in human prostate cancer
    • Sehgal I, Powers S, Huntley B, Powis G, Pittelkow M, Maihle NJ. Neurotensin is an autocrine trophic factor stimulated by androgen withdrawal in human prostate cancer. Proc. Natl Acad. Sci. USA 91(11), 4673-4677 (1994
    • (1994) Proc. Natl Acad. Sci. USA , vol.91 , Issue.11 , pp. 4673-4677
    • Sehgal, I.1    Powers, S.2    Huntley, B.3    Powis, G.4    Pittelkow, M.5    Maihle, N.J.6
  • 123
    • 80155131131 scopus 로고    scopus 로고
    • Inhibition of neurotensin receptor 1 selectively sensitizes prostate cancer to ionizing radiation
    • Valerie NC, Casarez EV, Dasilva JO et al. Inhibition of neurotensin receptor 1 selectively sensitizes prostate cancer to ionizing radiation. Cancer Res. 71(21), 6817-6826 (2011)
    • (2011) Cancer Res , vol.71 , Issue.21 , pp. 6817-6826
    • Valerie, N.C.1    Casarez, E.V.2    Dasilva, J.O.3
  • 124
    • 0642310760 scopus 로고    scopus 로고
    • Radiolabeled neurotensin analog, 99mTc-NT-XI, evaluated in ductal pancreatic adenocarcinoma patients
    • Buchegger F, Bonvin F, Kosinski M et al. Radiolabeled neurotensin analog, 99mTc-NT-XI, evaluated in ductal pancreatic adenocarcinoma patients. J. Nucl. Med. 44(10), 1649-1654 (2003
    • (2003) J. Nucl. Med , vol.44 , Issue.10 , pp. 1649-1654
    • Buchegger, F.1    Bonvin, F.2    Kosinski, M.3


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