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Volumn 71, Issue 21, 2011, Pages 6817-6826

Inhibition of neurotensin receptor 1 selectively sensitizes prostate cancer to ionizing radiation

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN; ANDROGEN RECEPTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; MECLINERTANT; NEUROTENSIN RECEPTOR; NEUROTENSIN RECEPTOR 1; UNCLASSIFIED DRUG;

EID: 80155131131     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-11-1646     Document Type: Article
Times cited : (38)

References (51)
  • 3
    • 72449146786 scopus 로고    scopus 로고
    • Radical radiotherapy for prostate cancer is the "only way to go."
    • Williston Park, N.Y.
    • Sandler HM, Mirhadi AJ. Radical radiotherapy for prostate cancer is the "only way to go." Oncology (Williston Park, N.Y.) 2009;23: 840-3.
    • (2009) Oncology , vol.23 , pp. 840-843
    • Sandler, H.M.1    Mirhadi, A.J.2
  • 4
    • 70350102549 scopus 로고    scopus 로고
    • Acute toxicity of curative radiotherapy for intermediate- And high-risk localised prostate cancer in the EORTC trial 22991
    • Matzinger O, Duclos F, van den Bergh A, Carrie C, Villà S, Kitsios P, et al. Acute toxicity of curative radiotherapy for intermediate- and high-risk localised prostate cancer in the EORTC trial 22991. Eur J Cancer 2009;45:2825-34.
    • (2009) Eur J Cancer , vol.45 , pp. 2825-2834
    • Matzinger, O.1    Duclos, F.2    Van Den Bergh, A.3    Carrie, C.4    Villà, S.5    Kitsios, P.6
  • 6
    • 0344457271 scopus 로고    scopus 로고
    • Neuroendocrine differentiation in prostatic carcinoma
    • Abrahamsson PA. Neuroendocrine differentiation in prostatic carcinoma. Prostate 1999;39:135-48.
    • (1999) Prostate , vol.39 , pp. 135-148
    • Abrahamsson, P.A.1
  • 8
    • 0029680203 scopus 로고    scopus 로고
    • Neuroendocrine differentiation in prostatic malignancy
    • DOI 10.1002/(SICI)1097-0142(19960715)78:2<357::AID-CNCR27>3.0.CO;2- U
    • di Sant'Agnese PA, Cockett AT. Neuroendocrine differentiation in prostatic malignancy. Cancer 1996;78:357-61. (Pubitemid 26234584)
    • (1996) Cancer , vol.78 , Issue.2 , pp. 357-361
    • Di Sant'Agnese, P.A.1    Cockett, A.T.K.2
  • 9
    • 0035167146 scopus 로고    scopus 로고
    • Neuroendocrine differentiation in prostatic carcinoma: An update on recent developments
    • di Sant'Agnese PA. Neuroendocrine differentiation in prostatic carcinoma: an update on recent developments. Ann Oncol 2001;12:S135-40.
    • (2001) Ann Oncol , vol.12
    • Di Sant'Agnese, P.A.1
  • 12
    • 0015821329 scopus 로고
    • The isolation of a new hypotensive peptide, neurotensin, from bovine hypothalami
    • Carraway R, Leeman SE. The isolation of a new hypotensive peptide, neurotensin, from bovine hypothalami. J Biol Chem 1973;248: 6854-61.
    • (1973) J Biol Chem , vol.248 , pp. 6854-6861
    • Carraway, R.1    Leeman, S.E.2
  • 13
    • 33748940753 scopus 로고    scopus 로고
    • Neurotensin and growth of normal and neoplastic tissues
    • Evers BM. Neurotensin and growth of normal and neoplastic tissues. Peptides 2006;27:2424-33.
    • (2006) Peptides , vol.27 , pp. 2424-2433
    • Evers, B.M.1
  • 14
    • 33748756339 scopus 로고    scopus 로고
    • Involvement of neurotensin in cancer growth: Evidence, mechanisms and development of diagnostic tools
    • DOI 10.1016/j.peptides.2006.04.030, PII S0196978106002956
    • Carraway RE, Plona AM. Involvement of neurotensin in cancer growth: evidence, mechanisms and development of diagnostic tools. Peptides 2006;27:2445-60. (Pubitemid 44402788)
    • (2006) Peptides , vol.27 , Issue.10 , pp. 2445-2460
    • Carraway, R.E.1    Plona, A.M.2
  • 15
    • 33846849466 scopus 로고    scopus 로고
    • Neurotensin stimulates mitogenesis of prostate cancer cells through a novel c-Src/Stat5b pathway
    • DOI 10.1038/sj.onc.1209814, PII 1209814
    • Amorino GP, Deeble PD, Parsons SJ. Neurotensin stimulates mitogenesis of prostate cancer cells through a novel c-Src/Stat5b pathway. Oncogene 2007;26:745-56. (Pubitemid 46204253)
    • (2007) Oncogene , vol.26 , Issue.5 , pp. 745-756
    • Amorino, G.P.1    Deeble, P.D.2    Parsons, S.J.3
  • 16
    • 33745700192 scopus 로고    scopus 로고
    • Expression of neurotensin and NT1 receptor in human breast cancer: A potential role in tumor progression
    • Souazé F, Dupouy S, Viardot-Foucault V, Bruyneel E, Attoub S, Gespach C, et al. Expression of neurotensin and NT1 receptor in human breast cancer: a potential role in tumor progression. Cancer Res 2006;66:6243-9.
    • (2006) Cancer Res , vol.66 , pp. 6243-6249
    • Souazé, F.1    Dupouy, S.2    Viardot-Foucault, V.3    Bruyneel, E.4    Attoub, S.5    Gespach, C.6
  • 18
    • 49049110032 scopus 로고    scopus 로고
    • Increased neurotensin receptor-1 expression during progression of colonic adenocarcinoma
    • Gui X, Guzman G, Dobner PR, Kadkol SS. Increased neurotensin receptor-1 expression during progression of colonic adenocarcinoma. Peptides 2008;29:1609-15.
    • (2008) Peptides , vol.29 , pp. 1609-1615
    • Gui, X.1    Guzman, G.2    Dobner, P.R.3    Kadkol, S.S.4
  • 19
    • 51949107050 scopus 로고    scopus 로고
    • Identification of a novel therapeutic target for head and neck squamous cell carcinomas: A role for the neurotensin-neurotensin receptor 1 oncogenic signaling pathway
    • Shimizu S, Tsukada J, Sugimoto T, Kikkawa N, Sasaki K, Chazono H, et al. Identification of a novel therapeutic target for head and neck squamous cell carcinomas: a role for the neurotensin-neurotensin receptor 1 oncogenic signaling pathway. Int J Cancer 2008;123: 1816-23.
    • (2008) Int J Cancer , vol.123 , pp. 1816-1823
    • Shimizu, S.1    Tsukada, J.2    Sugimoto, T.3    Kikkawa, N.4    Sasaki, K.5    Chazono, H.6
  • 20
    • 0034027795 scopus 로고    scopus 로고
    • Relevant genomics of neurotensin receptor in cancer
    • Elek J, Pinzon W, Park KH, Narayanan R. Relevant genomics of neurotensin receptor in cancer. Anticancer Res 2000;20:53-8. (Pubitemid 30189733)
    • (2000) Anticancer Research , vol.20 , Issue.1 A , pp. 53-58
    • Elek, J.1    Pinzon, W.2    Park, K.H.3    Narayanan, R.4
  • 21
    • 75149164771 scopus 로고    scopus 로고
    • Altered expression of neurotensin receptors is associated with the differentiation state of prostate cancer
    • Swift SL, Burns JE, Maitland NJ. Altered expression of neurotensin receptors is associated with the differentiation state of prostate cancer. Cancer Res 2010;70:347-56.
    • (2010) Cancer Res , vol.70 , pp. 347-356
    • Swift, S.L.1    Burns, J.E.2    Maitland, N.J.3
  • 22
    • 2642535866 scopus 로고    scopus 로고
    • Involvement of MAP-kinase, PI3-kinase and EGF-receptor in the stimulatory effect of Neurotensin on DNA synthesis in PC3 cells
    • DOI 10.1016/j.regpep.2004.03.004, PII S016701150400076X
    • Hassan S, Dobner PR, Carraway RE. Involvement of MAP-kinase, PI3- kinase and EGF-receptor in the stimulatory effect of Neurotensin on DNA synthesis in PC3 cells. Regul Pept 2004;120:155-66. (Pubitemid 38726205)
    • (2004) Regulatory Peptides , vol.120 , Issue.1-3 , pp. 155-166
    • Hassan, S.1    Dobner, P.R.2    Carraway, R.E.3
  • 23
    • 0028989925 scopus 로고
    • [3H]SR 48692, the first nonpeptide neurotensin antagonist radioligand: Characterization of binding properties and evidence for distinct agonist and antagonist binding domains on the rat neurotensin receptor
    • Labbé-Jullié C, Botto JM, Mas MV, Chabry J, Mazella J, Vincent JP, et al. [3H]SR 48692, the first nonpeptide neurotensin antagonist radioligand: characterization of binding properties and evidence for distinct agonist and antagonist binding domains on the rat neurotensin receptor. Mol Pharmacol 1995;47:1050-6.
    • (1995) Mol Pharmacol , vol.47 , pp. 1050-1056
    • Labbé-Jullié, C.1    Botto, J.M.2    Mas, M.V.3    Chabry, J.4    Mazella, J.5    Vincent, J.P.6
  • 24
    • 0029086090 scopus 로고
    • Characterization of the effect of SR48692 on inositol monophosphate, cyclic GMP and cyclic AMP responses linked to neurotensin receptor activation in neuronal and non-neuronal cells
    • Oury-Donat F, Thurneyssen O, Gonalons N, Forgez P, Gully D, Le Fur G, et al. Characterization of the effect of SR48692 on inositol monophosphate, cyclic GMP and cyclic AMP responses linked to neurotensin receptor activation in neuronal and non-neuronal cells. Br J Pharmacol 1995;116:1899-905.
    • (1995) Br J Pharmacol , vol.116 , pp. 1899-1905
    • Oury-Donat, F.1    Thurneyssen, O.2    Gonalons, N.3    Forgez, P.4    Gully, D.5    Le Fur, G.6
  • 25
    • 0030986240 scopus 로고    scopus 로고
    • Use of nonpeptide antagonists to explore the physiological roles of neurotensin. Focus on brain neurotensin/dopamine interactions
    • Rostene W, Azzi M, Boudin H, Lepee I, Souaze F, Mendez-Ubach M, et al. Use of nonpeptide antagonists to explore the physiological roles of neurotensin. Focus on brain neurotensin/dopamine interactions. Ann N Y Acad Sci 1997;814:125-41.
    • (1997) Ann N Y Acad Sci , vol.814 , pp. 125-141
    • Rostene, W.1    Azzi, M.2    Boudin, H.3    Lepee, I.4    Souaze, F.5    Mendez-Ubach, M.6
  • 27
    • 0030988580 scopus 로고    scopus 로고
    • Inhibition of neurotensin-induced pancreatic carcinoma growth by a nonpeptide neurotensin receptor antagonist, SR48692
    • DOI 10.1002/(SICI)1097-0142(19970501)79:9<1787::AID-CNCR22>3.0. CO;2-T
    • Iwase K, Evers BM, Hellmich MR, Kim HJ, Higashide S, Gully D, et al. Inhibition of neurotensin-induced pancreatic carcinoma growth by a nonpeptide neurotensin receptor antagonist, SR48692. Cancer 1997;79:1787-93. (Pubitemid 27176362)
    • (1997) Cancer , vol.79 , Issue.9 , pp. 1787-1793
    • Iwase, K.1    Evers, B.M.2    Hellmich, M.R.3    Kim, H.J.4    Higashide, S.5    Gully, D.6    Thompson, J.C.7    Townsend Jr., C.M.8
  • 28
    • 0032942578 scopus 로고    scopus 로고
    • Neurotensin receptor-mediated inhibition of pancreatic cancer cell growth by the neurotensin antagonist SR 48692
    • Herzig MC, Chapman WG, Sheridan A, Rake JB, Woynarowski JM. Neurotensin receptor-mediated inhibition of pancreatic cancer cell growth by the neurotensin antagonist SR 48692. Anticancer Res 1999;19:213-9. (Pubitemid 29168240)
    • (1999) Anticancer Research , vol.19 , Issue.1 A , pp. 213-219
    • Herzig, M.C.S.1    Chapman, W.G.2    Sheridan, A.3    Rake, J.B.4    Woynarowski, J.M.5
  • 29
    • 0030911673 scopus 로고    scopus 로고
    • Neurotensin receptor expression in prostate cancer cell line and growth effect of NT at physiological concentrations
    • DOI 10.1002/(SICI)1097-0045(19970515)31:3<183::AID-PROS7>3.0.CO;2-M
    • Seethalakshmi L, Mitra SP, Dobner PR, Menon M, Carraway RE. Neurotensin receptor expression in prostate cancer cell line and growth effect of NT at physiological concentrations. Prostate 1997; 31:183-92. (Pubitemid 27225203)
    • (1997) Prostate , vol.31 , Issue.3 , pp. 183-192
    • Seethalakshmi, L.1    Mitra, S.P.2    Dobner, P.R.3    Menon, M.4    Carraway, R.E.5
  • 30
    • 0035130471 scopus 로고    scopus 로고
    • SR48692 is a neurotensin receptor antagonist which inhibits the growth of small cell lung cancer cells
    • DOI 10.1016/S0196-9781(00)00362-4, PII S0196978100003624
    • Moody TW, Chiles J, Casibang M, Moody E, Chan D, Davis TP. SR48692 is a neurotensin receptor antagonist which inhibits the growth of small cell lung cancer cells. Peptides 2001;22:109-15. (Pubitemid 32146689)
    • (2001) Peptides , vol.22 , Issue.1 , pp. 109-115
    • Moody, T.W.1    Chiles, J.2    Casibang, M.3    Moody, E.4    Chan, D.5    Davis, T.P.6
  • 31
    • 0028321891 scopus 로고
    • Derivation of androgen-independent human LNCaP prostatic cancer cell sublines: Role of bone stromal cells
    • DOI 10.1002/ijc.2910570319
    • Wu HC, Hsieh JT, Gleave ME, Brown NM, Pathak S, Chung LW. Derivation of androgen-independent human LNCaP prostatic cancer cell sublines: role of bone stromal cells. Int J Cancer 1994;57:406-12. (Pubitemid 24168617)
    • (1994) International Journal of Cancer , vol.57 , Issue.3 , pp. 406-412
    • Wu, H.-C.1    Hsieh, J.-T.2    Gleave, M.E.3    Brown, N.M.4    Pathak, S.5    Chung, L.W.K.6
  • 33
    • 0035874064 scopus 로고    scopus 로고
    • Involvement of the neurotensin receptor subtype NTR3 in the growth effect of neurotensin on cancer cell lines
    • DOI 10.1002/ijc.1225
    • Dal Farra C, Sarret P, Navarro V, Botto JM, Mazella J, Vincent JP. Involvement of the neurotensin receptor subtype NTR3 in the growth effect of neurotensin on cancer cell lines. Int J Cancer 2001;92:503-9. (Pubitemid 32319423)
    • (2001) International Journal of Cancer , vol.92 , Issue.4 , pp. 503-509
    • Dal, F.C.1    Sarret, P.2    Navarro, V.3    Botto, J.-M.4    Mazella, J.5    Vincent, J.-P.6
  • 34
    • 0010349948 scopus 로고    scopus 로고
    • Efficacy and toxicity of replication-competent adenovirus-mediated double suicide gene therapy in combination with radiation therapy in an orthotopic mouse prostate cancer model
    • Freytag SO, Paielli D, Wing M, Rogulski K, Brown S, Kolozsvary A, et al. Efficacy and toxicity of replication-competent adenovirus-mediated double suicide gene therapy in combination with radiation therapy in an orthotopic mouse prostate cancer model. Int J Radiat Oncol Biol Phys 2002;54:873-85.
    • (2002) Int J Radiat Oncol Biol Phys , vol.54 , pp. 873-885
    • Freytag, S.O.1    Paielli, D.2    Wing, M.3    Rogulski, K.4    Brown, S.5    Kolozsvary, A.6
  • 35
    • 0348140962 scopus 로고    scopus 로고
    • In vivo monitoring of tumor relapse and metastasis using bioluminescent PC-3M-luc-C6 cells in murine models of human prostate cancer
    • DOI 10.1023/B:CLIN.0000006817.25962.87
    • Jenkins DE, Yu S-F, Hornig YS, Purchio T, Contag PR. In vivo monitoring of tumor relapse and metastasis using bioluminescent PC-3M-luc-C6 cells in murine models of human prostate cancer. Clin Exp Metastasis 2003;20:745-56. (Pubitemid 38019276)
    • (2003) Clinical and Experimental Metastasis , vol.20 , Issue.8 , pp. 745-756
    • Jenkins, D.E.1    Yu, S.-F.2    Hornig, Y.S.3    Purchio, T.4    Contag, P.R.5
  • 36
    • 69949126092 scopus 로고    scopus 로고
    • Radiation-induced lipid peroxidation activates src kinase and triggers nuclear EGFR transport
    • Dittmann K, Mayer C, Kehlbach R, Rothmund M-C, Peter Rodemann H. Radiation-induced lipid peroxidation activates src kinase and triggers nuclear EGFR transport. Radiother Oncol 2009;92:379-82.
    • (2009) Radiother Oncol , vol.92 , pp. 379-382
    • Dittmann, K.1    Mayer, C.2    Kehlbach, R.3    Rothmund, M.-C.4    Peter Rodemann, H.5
  • 37
    • 17644402851 scopus 로고    scopus 로고
    • Requirement of Tyr-992 and Tyr-1173 in phosphorylation of the epidermal growth factor receptor by ionizing radiation and modulation by SHP2
    • DOI 10.1074/jbc.M413287200
    • Sturla L-M, Amorino G, Alexander MS, Mikkelsen RB, Valerie K, Schmidt-Ullrichr RK. Requirement of Tyr-992 and Tyr-1173 in phosphorylation of the epidermal growth factor receptor by ionizing radiation and modulation by SHP2. J Biol Chem 2005;280: 14597-604. (Pubitemid 40562804)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.15 , pp. 14597-14604
    • Sturla, L.-M.1    Amorino, G.2    Alexander, M.S.3    Mikkelsen, R.B.4    Valerie, K.5    Schmidt-Ullrich, R.K.6
  • 38
    • 0036022402 scopus 로고    scopus 로고
    • Poly(ADP-ribose) polymerase-1 cleavage during apoptosis: An update
    • DOI 10.1023/A:1016119328968
    • Soldani C, Scovassi AI. Poly(ADP-ribose) polymerase-1 cleavage during apoptosis: an update. Apoptosis 2002;7:321-8. (Pubitemid 34832256)
    • (2002) Apoptosis , vol.7 , Issue.4 , pp. 321-328
    • Soldani, C.1    Scovassi, A.I.2
  • 40
    • 52649108603 scopus 로고    scopus 로고
    • The combination of epidermal growth factor receptor inhibitors with gemcitabine and radiation in pancreatic cancer
    • Morgan MA, Parsels LA, Kollar LE, Normolle DP, Maybaum J, Lawrence TS. The combination of epidermal growth factor receptor inhibitors with gemcitabine and radiation in pancreatic cancer. Clin Cancer Res 2008;14:5142-9.
    • (2008) Clin Cancer Res , vol.14 , pp. 5142-5149
    • Morgan, M.A.1    Parsels, L.A.2    Kollar, L.E.3    Normolle, D.P.4    Maybaum, J.5    Lawrence, T.S.6
  • 41
    • 16544370387 scopus 로고    scopus 로고
    • Neurotensin negatively modulates Akt activity in neurotensin receptor-1-transfected AV12 cells
    • Liu F, Yang P, Baez M, Ni B. Neurotensin negatively modulates Akt activity in neurotensin receptor-1-transfected AV12 cells. J Cell Biochem 2004;92:603-11.
    • (2004) J Cell Biochem , vol.92 , pp. 603-611
    • Liu, F.1    Yang, P.2    Baez, M.3    Ni, B.4
  • 42
    • 41749123020 scopus 로고    scopus 로고
    • Differential efficacy of combined therapy with radiation and AEE788 in high and low EGFR-expressing androgen-independent prostate tumor models
    • Huamani J, Willey C, Thotala D, Niermann KJ, Reyzer M, Leavitt L, et al. Differential efficacy of combined therapy with radiation and AEE788 in high and low EGFR-expressing androgen-independent prostate tumor models. Int J Radiat Oncol Biol Phys 2008;71: 237-46.
    • (2008) Int J Radiat Oncol Biol Phys , vol.71 , pp. 237-246
    • Huamani, J.1    Willey, C.2    Thotala, D.3    Niermann, K.J.4    Reyzer, M.5    Leavitt, L.6
  • 45
    • 0037442515 scopus 로고    scopus 로고
    • Involvement of the neurotensin receptor-3 in the neurotensin-induced migration of human microglia
    • Martin S, Vincent J-P, Mazella J. Involvement of the neurotensin receptor-3 in the neurotensin-induced migration of human microglia. J Neurosci 2003;23:1198-205. (Pubitemid 36258899)
    • (2003) Journal of Neuroscience , vol.23 , Issue.4 , pp. 1198-1205
    • Martin, S.1    Vincent, J.-P.2    Mazella, J.3
  • 47
    • 0037382033 scopus 로고    scopus 로고
    • Involvement of primary afferent nerves after abdominal irradiation: Consequences on ileal contractile activity and inflammatory mediator release in the rat
    • DOI 10.1023/A:1022872322578
    • Linard C, Marquette C, Strup C, Aigueperse J, Mathe D. Involvement of primary afferent nerves after abdominal irradiation: consequences on ileal contractile activity and inflammatory mediator release in the rat. Dig Dis Sci 2003;48:688-97. (Pubitemid 36390669)
    • (2003) Digestive Diseases and Sciences , vol.48 , Issue.4 , pp. 688-697
    • Linard, C.1    Marquette, C.2    Strup, C.3    Aigueperse, J.4    Mathe, D.5
  • 48
    • 63749101351 scopus 로고    scopus 로고
    • Targeting the EGFR and the PKB pathway in cancer
    • Klein S, Levitzki A. Targeting the EGFR and the PKB pathway in cancer. Curr Opin Cell Biol 2009;21:185-93.
    • (2009) Curr Opin Cell Biol , vol.21 , pp. 185-193
    • Klein, S.1    Levitzki, A.2
  • 49
    • 2342565881 scopus 로고    scopus 로고
    • Advances in protein kinase B signalling: AKTion on multiple fronts
    • DOI 10.1016/j.tibs.2004.03.006, PII S096800040400074X
    • Brazil DP, Yang Z-Z, Hemmings BA. Advances in protein kinase B signalling: AKTion on multiple fronts. Trends Biochem Sci 2004; 29:233-42. (Pubitemid 38591317)
    • (2004) Trends in Biochemical Sciences , vol.29 , Issue.5 , pp. 233-242
    • Brazil, D.P.1    Yang, Z.-Z.2    Hemmings, B.A.3
  • 50
    • 34547650639 scopus 로고    scopus 로고
    • Targeting Akt in cancer therapy
    • DOI 10.1097/CAD.0b013e3280cc2c6f, PII 0000181320070900000001
    • LoPiccolo J, Granville CA, Gills JJ, Dennis PA. Targeting Akt in cancer therapy. Anticancer Drugs 2007;18:861-74. (Pubitemid 47220704)
    • (2007) Anti-Cancer Drugs , vol.18 , Issue.8 , pp. 861-874
    • LoPiccolo, J.1    Granville, C.A.2    Gills, J.J.3    Dennis, P.A.4


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