Gastrin-releasing peptide receptors in the human prostate: Relation to neoplastic transformation

Cancer Research

Volumn 59, Issue 5, 1999, Pages 1152-1159

  Markwalder, Regula ^a   Reubi, Jean Claude ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BOMBESIN; GASTRIN RELEASING PEPTIDE;

ARTICLE; AUTORADIOGRAPHY; CELL DIFFERENTIATION; CELL PROLIFERATION; GASTRIN RELEASE; GROWTH INHIBITION; HUMAN; HUMAN TISSUE; MALIGNANT TRANSFORMATION; MEMBRANE BINDING; MOLECULAR CLONING; PRIORITY JOURNAL; PROSTATE CANCER; SCINTIGRAPHY; TUMOR GROWTH; TUMOR LOCALIZATION; TUMOR MODEL;

AGED; AGED, 80 AND OVER; AUTORADIOGRAPHY; BONE NEOPLASMS; CELL TRANSFORMATION, NEOPLASTIC; HUMANS; HYPERPLASIA; IODINE RADIOISOTOPES; MALE; MIDDLE AGED; NEOPLASM INVASIVENESS; PROSTATE; PROSTATIC NEOPLASMS; RADIOLIGAND ASSAY; RECEPTORS, BOMBESIN; URINARY BLADDER NEOPLASMS;

EID: 0033104343     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (47)

1. Reubi, J. C. Neuropeptide receptors in health and disease: the molecular basis for in vivo imaging. J. Nucl. Med., 36: 1825-1835, 1995.
2. Reubi, J. C. In vitro identification of vasoactive intestinal peptide receptors in human tumors: implications for tumor imaging. J. Nucl. Med., 36: 1846-1853, 1995.
3. Reubi, J. C., and Waser, B. Unexpected high incidence of cholecystokinin B/gastrin receptors in human medullary thyroid carcinomas. Int. J. Cancer, 67: 644-647, 1996.
4. Reubi, J. C., Schaer, J. C., and Waser, B. Cholecystokinin(CCK)-A, and CCK-B/ gastrin receptors in human tumors. Cancer Res., 57: 1377-1386, 1997.
5. Krenning, E. P., Kwekkeboom, D. J., Pauwels, S., Kvols, L. K., and Reubi, J. C. Somatostatin receptor scintigraphy. Nucl. Med. Annu., 1995: 1-50, 1995.
6. Virgolini, I., Raderer, M., Kurtaran, A., Angelberger, P., Banyai, S., Yang, Q., Li, S., Banyai, M., Pidlich, J., Niederle, B., Scheithauer, W., and Valent, P. Vasoactive intestinal peptide-receptor imaging for the localization of intestinal adenocarcinomas and endocrine tumors. N. Engl. J. Med., 331: 1116-1121, 1994.
7. Behr, T. M., Jenner, N., Radetzky, S., Béhe, M., Gratz, S., Yücekent, S., Raue, F., and Becker, W. Targeting of cholecystokinin-B/gastrin receptors in vivo: preclinical and initial clinical evaluation of the diagnostic and therapeutic potential of radiolabelled gastrin. Eur. J. Nucl. Med., 25: 424-430, 1998.
8. Otte, A., Mueller-Brand, J., Dellas, S., Nitzsche, E. U., Herrmann, R., and Maecke, H. R. Yttrium-90-labelled somatostatin-analogue for cancer treatment. Lancet, 351: 417-418, 1998.
9. Nagy, A., Schally, A. V., Halmos, G., Armatis, P., Cai, R., Csernus, V., Kovacs, M., Koppan, M., Szepeshazi, K., and Kahan, Z. Synthesis and biological evaluation of cytotoxic analogs of somatostatin containing doxorubicin or its intensely potent derivative, 2-pyrrolinodoxorubicin. Proc. Natl. Acad. Sci. USA, 95: 1794-1799, 1998.
10. Zia, H., Hida, T., Jakowlew, S., Birrer, M., Gozes, Y., Reubi, J. C., Fridkin, M., Gozes, I., and Moody, T. W. Breast cancer growth is inhibited by vasoactive intestinal peptide (VIP) hybrid, a synthetic VIP receptor antagonist. Cancer Res., 56: 3486-3489, 1996.
11. Erspamer, V. Discovery, isolation, and characterization of bombesin-like peptides. Ann. NY Acad. Sci., 547: 3-9, 1988.
12. Rozengurt, E. Bombesin stimulation of mitogenesis. Specific receptors, signal transduction and early events. Am. Rev. Respir. Dis., 142: S11-S15, 1990.
13. Cuttitta, F., Carney, D. N., Mulshine, J., Moody, T. W., Fedorko, J., Fischler, A., and Minna, J. D. Bombesin-like peptides can function as autocrine growth factors in human small-cell lung cancer. Nature (Lond.), 316: 823-825, 1985.
14. Carney, D. N., Cuttitta, F., Moody, T. W., and Minna, J. D. Selective stimulation of small cell lung cancer clonal growth by bombesin and gastrin-releasing peptide. Cancer Res., 47: 821-825, 1987.
15. Moody, T. W., and Cuttitta, F. Growth factor and peptide receptors in small cell lung cancer. Life Sci., 52: 1161-1173, 1993.
16. Bologna, M. C., Festuccia, C., Muzi, P., Biordi, L., and Ciomei, M. Bombesin stimulates growth of human prostatic cancer cells in vitro. Cancer (Phila.), 63: 1714-1720, 1989.
17. Pinski, J., Reile, H., Halmos, G., Groot, K., and Schally, A. V. Inhibitory effects of somatostatin analogue RC-160 and bombesin/gastrin-releasing peptide antagonist RC-3095 on the growth of the androgen-independent Dunning R-3327-AT-1 rat prostate cancer. Cancer Res., 54: 169-174, 1994.
18. Milovanovic, S. R., Radulovic, S., Groot, K., and Schally, A. V. Inhibition of growth of PC-82 human prostate cancer cell line xenografts in nude mice by bombesin antagonist RC-3095 or combination of agonist [D-Trp6]-luteinizing hormone-releasing hormone and somatostatin analog RC-160. Prostate, 20: 269-280, 1992.
19. Jungwirth, A., Pinski, J., Galvan, G., Halmos, G., Szepeshazi, K., Cai, R. Z., Groot, K., Vadillo-Buenfil, M., and Schally, A. V. Inhibition of growth of androgen-independent DU-145 prostate cancer in vivo by luteinising hormone-releasing hormone antagonist cetrorelix and bombesin antagonists RC-3940-II and RC-3950-II. Eur. J. Cancer. 33: 1141-1148, 1997.
20. Aprikian, A. G., Han, K., Chevalier, S., Bazmet, M., and Viallet, I. Bombesin specifically induces intracellular calcium mobilization via gastrin-releasing peptide receptors in human prostate cancer cells. J. Mol. Endocrinol., 16: 297-306, 1996.
21. Wu, J. M., Hoang, D. O., and Feldman, R. I. Differential activation of human gastrin-releasing peptide receptor-mediated responses by bombesin analogs. Mol. Pharmacol., 47: 871-881, 1995.
22. Reile, H., Armatis, P. E., and Schally, A. V. Characterization of high-affinity receptors for bombesin/gastrin-releasing peptide on the human prostate cancer cell lines PC-3 and DU-145: Internalization of receptor bound 125-I-(Tyr4)bombesin by tumor cells. Prostate, 25: 29-38, 1994.
23. Feldman, R. I., Bartholdi, M. F., and Wu, J. M. Bombesin-like peptide receptor subtypes promote mitogenesis which requires persistent receptor signaling. Mol. Pharmacol., 50: 1346-1354, 1996.
24. Reubi, J. C. Relevance of somatostatin receptors and other peptide receptors in pathology. Endocrinol. Pathol., 8: 11-20, 1997.
25. Epstein, J. I. Prostatic intraepithelial neoplasia. In: J. I. Epstein (ed.), Prostate Biopsy Interpretation, 2nd ed, pp. 37-64. Philadelphia: Lippincott-Raven, 1995.
26. 1)-octreotide scintigraphy. Cancer Res., 55 (Suppl.): 5805s-5810s, 1995.
27. Mostofi, F. K. Grading of prostatic carcinoma. Cancer Chemother. Rep., 59; 111 117, 1975.
28. Gleason, D. F., and Veterans Administration Cooperative Urological Research Group. Histologic grading and clinical staging of prostatic carcinoma. In: M. Tannenbaum (ed.), Urologic Pathology: The Prostate, pp. 171-197. Philadelphia: Lea & Febiger, 1977.
29. Bostwick, D. G. High grade prostatic intraepithelial neoplasia. Cancer (Phila.), 75: 1823-1836, 1995.
30. Rubin, M. A., DeLaTaille, A., Bagiella, E., Olsson, C. A., and O'Toole, K. M. Cribriform carcinoma of the prostate and cribriform prostatic intraepithlial neoplasia. Am. J. Surg. Pathol., 22: 840-848, 1998.
31. Reubi, J. C., Kvols, L. K., Waser, B., Nagorney, D., Heitz, P. U., Charboneau, J. W., Reading, C. C., and Moertel, C. Detection of somatostatin receptors in surgical and percutaneous needle biopsy samples of carcinoids and islet cell carcinomas. Cancer Res., 50: 5969-5977, 1990.
32. Vigna, S. R., Mantyh, C. R., Giraud, A. S., Soil, A. H., Walsh, J. H., and Mantyh, P. W. Localization of specific binding sites for bombesin in the canine gastrointestinal tract. Gastroenterology, 93: 1287-1295, 1987.
33. Battey, J., and Wada, E. Two distinct receptor subtypes for mammalian bombesin receptors. Trends Neurosci., 14: 524-528, 1991.
34. Jensen, R. T., and Coy, D. H. Progress in the development of potent bombesin receptor antagonists. Trends Pharmacol. Sci., 12: 13-19, 1991.
35. Mantey, S. A., Weber, H. C., Sainz, E., Akeson, M., Ryan, R. R., Pradhan, T. K., Searles, R. P., Spindel, E. R., Battey, J. F., Coy, D. H., and Jensen, R. T. Discovery of a high affinity radioligand for the human orphan receptor, bombesin receptor subtype 3, which demonstrates that it has a unique pharmacology compared with other mammalian bombesin receptors. J. Biol. Chem., 272: 26062-26071, 1997.
36. Bartholdi, M. F., Wu, J. M., Pu, H., Troncoso, P., Eden, P. A., and Feldman, R. I. In situ hybridization for gastrin-releasing peptide receptor (GRP receptor) expression in prostatic carcinoma. Int. J. Cancer (Predict. Oncol.), 79: 82-90, 1998.
37. Wang, F., Wang, Y., Wong, W., Liu, A., Addivilona, F. J., Liang, P., Chen, L. B., Kantoff, P. W., and Pardee, A. B. Two differentially expressed genes in normal human prostate tissue and in carcinoma. Cancer Res., 56: 3634-3637, 1996.
38. Aprikian, A. G., Cordon-Cardo, C., Fair, W. R., and Reuter, V. E. Characterization of neuroendocrine differentiation in human benign prostate and prostatic adenocarcinoma. Cancer (Phila.), 71: 3952-3965, 1993.
39. Di SantAgnese, P. A. Neuroendocrine differentiation in carcinoma of the prostate. Cancer (Phila.), 70 (Suppl.): 254-268, 1992.
40. Reubi, J. C., Waser, B., Schaer, J. C., and Markwalder, R. Somatostatin receptors in human prostate and prostate cancer. J. Clin. Endocrinol. Metab., 80: 2806-2814, 1995.
41. Chung, L. W., Gleave, M. E., Hsieh, J. T., Hong, S. J., and Zhau, H. E. Reciprocal mesenchymal-epithelial interaction affecting prostate tumour growth and hormonal responsiveness. Cancer Surv., 11: 91-121, 1991.
42. de Castiglione, R., and Gozzini, L. Bombesin receptor antagonists. Crit. Rev. Oncol. Hematol., 24: 117-151, 1996.
43. Moody, T. W., Venugopal, R., Zia, R., Patierno, S., Leban, J. J., and McDermed, J. BW2258U89: a GRP antagonist which inhibits small cell lung cancer. Life Sci., 56: 521-529, 1995.
44. Nagy, A., Armatis, P., Cai, R., Szepeshazi, K., Halmos, G., and Serially, A. V. Design, synthesis, and in vitro evaluation of cytotoxic analogs of bombesin-like peptides containing doxorubicin or its intensely potent derivative, 2-pyrrolinodoxorubicin. Proc. Natl. Acad. Sci. USA, 94: 652-656, 1997.
45. Baidoo, K. E., Lin, K., Zhan, Y., Finley, P., Scheffel, U., and Wagner, H. N., Jr. Design, synthesis, and initial evaluation of high-affinity technetium bombesin analogues. Bioconjugate Chem., 9: 218-225, 1998.
46. Safavy, A., Khazaeli, M. B., Qin, H., and Buchsbaum, D. J. Synthesis of bombesin analogues for radiolabeling with rhenium-188. Cancer (Phila.), 80 (Suppl.): 2354-2359, 1997.
47. Hoffman, T. J., Li, N., Sieckman, G. L., Higginbotham, C. A., and Volkert, W. A. Evaluation of radiolabeled (I-125 vs. Rh-105)bombesin analogue internalization in normal and tumor cell lines. Q. J. Nucl. Med., 41(Suppl. 1): 5, 1997.