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Volumn 14, Issue 1, 2015, Pages

Effect of a high fat, high sucrose diet on the promotion of non-alcoholic fatty liver disease in male rats: The ameliorative role of three natural compounds

Author keywords

Berberine; Dyslipidemia; High fat high sucrose diet; Non alcoholic fatty liver disease; O coumaric acid; Peroxisome proliferator activated receptor ; Quercetin

Indexed keywords

BERBERINE; CHOLESTEROL; COUMARIC ACID; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLYCEROL 3 PHOSPHATE DEHYDROGENASE; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; QUERCETIN; TRIACYLGLYCEROL; TRIACYLGLYCEROL LIPASE; BIOLOGICAL PRODUCT; LIPID; MESSENGER RNA; SUCROSE;

EID: 84938352425     PISSN: None     EISSN: 1476511X     Source Type: Journal    
DOI: 10.1186/s12944-015-0087-1     Document Type: Article
Times cited : (65)

References (70)
  • 1
    • 77956866205 scopus 로고    scopus 로고
    • A Western-like fat diet is sufficient to induce a gradual enhancement in fat mass over generations
    • 1:CAS:528:DC%2BC3cXpvVOks78%3D 2903802 20410018
    • Massiera F, Barbry P, Guesnet P, Joly A, Luquet S, Moreilhon-Brest C, et al. A Western-like fat diet is sufficient to induce a gradual enhancement in fat mass over generations. J Lipid Res. 2010;51:2352-61.
    • (2010) J Lipid Res , vol.51 , pp. 2352-2361
    • Massiera, F.1    Barbry, P.2    Guesnet, P.3    Joly, A.4    Luquet, S.5    Moreilhon-Brest, C.6
  • 2
    • 79952213256 scopus 로고    scopus 로고
    • Rodent models for metabolic syndrome research
    • Panchal SK, Brown L. Rodent models for metabolic syndrome research. J Biomed Biotechnol. 2011;2011:351982.
    • (2011) J Biomed Biotechnol , vol.2011
    • Panchal, S.K.1    Brown, L.2
  • 3
    • 79960847840 scopus 로고    scopus 로고
    • Nonalcoholic fatty liver disease and diabetes mellitus: Pathogenesis and treatment
    • 1:CAS:528:DC%2BC3MXptlOqsrw%3D 21556019
    • Smith BW, Adams LA. Nonalcoholic fatty liver disease and diabetes mellitus: pathogenesis and treatment. Nat Rev Endocrinol. 2011;7:456-65.
    • (2011) Nat Rev Endocrinol , vol.7 , pp. 456-465
    • Smith, B.W.1    Adams, L.A.2
  • 4
    • 84874045511 scopus 로고    scopus 로고
    • The origins and drivers of insulin resistance
    • 1:CAS:528:DC%2BC3sXis1Oqs70%3D 23415219
    • Johnson AM, Olefsky JM. The origins and drivers of insulin resistance. Cell. 2013;152:673-84.
    • (2013) Cell , vol.152 , pp. 673-684
    • Johnson, A.M.1    Olefsky, J.M.2
  • 5
    • 77956550077 scopus 로고    scopus 로고
    • Differential effects of high-carbohydrate and high-fat diet composition on muscle insulin resistance in rats
    • 1:CAS:528:DC%2BC3cXhtVSlurnO 2890883 20592898
    • Chun M-R, Lee YJ, Kim K-H, Kim Y-W, Park S-Y, Lee K-M, et al. Differential effects of high-carbohydrate and high-fat diet composition on muscle insulin resistance in rats. J Korean Med Sci. 2010;25:1053-9.
    • (2010) J Korean Med Sci , vol.25 , pp. 1053-1059
    • Chun, M.-R.1    Lee, Y.J.2    Kim, K.-H.3    Kim, Y.-W.4    Park, S.-Y.5    Lee, K.-M.6
  • 6
    • 77956634470 scopus 로고    scopus 로고
    • High-fructose, medium chain trans fat diet induces liver fibrosis and elevates plasma coenzyme Q9 in a novel murine model of obesity and nonalcoholic steatohepatitis
    • 1:CAS:528:DC%2BC3cXhtFyitr%2FP 2932817 20607689
    • Kohli R, Kirby M, Xanthakos SA, Softic S, Feldstein AE, Saxena V, et al. High-fructose, medium chain trans fat diet induces liver fibrosis and elevates plasma coenzyme Q9 in a novel murine model of obesity and nonalcoholic steatohepatitis. Hepatology. 2010;52:934-44.
    • (2010) Hepatology , vol.52 , pp. 934-944
    • Kohli, R.1    Kirby, M.2    Xanthakos, S.A.3    Softic, S.4    Feldstein, A.E.5    Saxena, V.6
  • 7
    • 0035057623 scopus 로고    scopus 로고
    • Dietary diacylglycerol suppresses high fat and high sucrose diet-induced body fat accumulation in C57BL/6 J mice
    • 1:CAS:528:DC%2BD3MXisFSrsrs%3D 11254749
    • Murase T, Mizuno T, Omachi T, Onizawa K, Komine Y, Kondo H, et al. Dietary diacylglycerol suppresses high fat and high sucrose diet-induced body fat accumulation in C57BL/6 J mice. J Lipid Res. 2001;42:372-8.
    • (2001) J Lipid Res , vol.42 , pp. 372-378
    • Murase, T.1    Mizuno, T.2    Omachi, T.3    Onizawa, K.4    Komine, Y.5    Kondo, H.6
  • 8
    • 77957606885 scopus 로고    scopus 로고
    • Antiobesity effect of eicosapentaenoic acid in high-fat/high-sucrose diet-induced obesity importance of hepatic lipogenesis
    • 1:CAS:528:DC%2BC3cXhsVGhs7nE 3279525 20682690
    • Sato A, Kawano H, Notsu T, Ohta M, Nakakuki M, Mizuguchi K, et al. Antiobesity effect of eicosapentaenoic acid in high-fat/high-sucrose diet-induced obesity importance of hepatic lipogenesis. Diabetes. 2010;59:2495-504.
    • (2010) Diabetes , vol.59 , pp. 2495-2504
    • Sato, A.1    Kawano, H.2    Notsu, T.3    Ohta, M.4    Nakakuki, M.5    Mizuguchi, K.6
  • 9
    • 0035066651 scopus 로고    scopus 로고
    • Polyunsaturated fatty acid regulation of gene transcription: A molecular mechanism to improve the metabolic syndrome
    • 1:CAS:528:DC%2BD3MXjsl2iurw%3D 11285313
    • Clarke SD. Polyunsaturated fatty acid regulation of gene transcription: a molecular mechanism to improve the metabolic syndrome. J Nutr. 2001;131:1129-32.
    • (2001) J Nutr , vol.131 , pp. 1129-1132
    • Clarke, S.D.1
  • 10
    • 0141446024 scopus 로고    scopus 로고
    • Liver peroxisome proliferator-activated receptor γ contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass
    • 1:CAS:528:DC%2BD3sXmvVCqsLw%3D 12805374
    • Gavrilova O, Haluzik M, Matsusue K, Cutson JJ, Johnson L, Dietz KR, et al. Liver peroxisome proliferator-activated receptor γ contributes to hepatic steatosis, triglyceride clearance, and regulation of body fat mass. J Biol Chem. 2003;278:34268-76.
    • (2003) J Biol Chem , vol.278 , pp. 34268-34276
    • Gavrilova, O.1    Haluzik, M.2    Matsusue, K.3    Cutson, J.J.4    Johnson, L.5    Dietz, K.R.6
  • 12
    • 80051706346 scopus 로고    scopus 로고
    • Role for PPARγ in obesity-induced hepatic steatosis as determined by hepatocyte-and macrophage-specific conditional knockouts
    • 21507897
    • Morán-Salvador E, López-Parra M, García-Alonso V, Titos E, Martínez-Clemente M, González-Périz A, et al. Role for PPARγ in obesity-induced hepatic steatosis as determined by hepatocyte-and macrophage-specific conditional knockouts. FASEB J. 2011;25:2538-50.
    • (2011) FASEB J , vol.25 , pp. 2538-2550
    • Morán-Salvador, E.1    López-Parra, M.2    García-Alonso, V.3    Titos, E.4    Martínez-Clemente, M.5    González-Périz, A.6
  • 13
    • 0035798713 scopus 로고    scopus 로고
    • The mechanisms by which both heterozygous peroxisome proliferator-activated receptor γ (PPARγ) deficiency and PPARγ agonist improve insulin resistance
    • 1:CAS:528:DC%2BD3MXosVKgtrg%3D 11533050
    • Yamauchi T, Kamon J, Waki H, Murakami K, Motojima K, Komeda K, et al. The mechanisms by which both heterozygous peroxisome proliferator-activated receptor γ (PPARγ) deficiency and PPARγ agonist improve insulin resistance. J Biol Chem. 2001;276:41245-54.
    • (2001) J Biol Chem , vol.276 , pp. 41245-41254
    • Yamauchi, T.1    Kamon, J.2    Waki, H.3    Murakami, K.4    Motojima, K.5    Komeda, K.6
  • 14
    • 33749246068 scopus 로고    scopus 로고
    • Endothelial function and cardiovascular disease: Effects of quercetin and wine polyphenols
    • 1:CAS:528:DC%2BD28XhtVymurjO 17015250
    • Perez-Vizcaino F, Duarte J, Andriantsitohaina R. Endothelial function and cardiovascular disease: effects of quercetin and wine polyphenols. Free Radic Res. 2006;40:1054-65.
    • (2006) Free Radic Res , vol.40 , pp. 1054-1065
    • Perez-Vizcaino, F.1    Duarte, J.2    Andriantsitohaina, R.3
  • 15
    • 0032813348 scopus 로고    scopus 로고
    • Molecular mechanisms of chemopreventive effects of selected dietary and medicinal phenolic substances
    • 1:CAS:528:DyaK1MXltlCqsbs%3D 10518003
    • Surh Y-J. Molecular mechanisms of chemopreventive effects of selected dietary and medicinal phenolic substances. Mutat Res. 1999;428:305-27.
    • (1999) Mutat Res , vol.428 , pp. 305-327
    • Surh, Y.-J.1
  • 16
    • 80054986567 scopus 로고    scopus 로고
    • Phytochemicals as potential agents for prevention and treatment of obesity and metabolic diseases
    • Park T, Kim Y. Phytochemicals as potential agents for prevention and treatment of obesity and metabolic diseases. Anti-Obes Drug Discov Dev Bentham, Dubai. 2011;1:150-185.
    • (2011) Anti-Obes Drug Discov Dev Bentham, Dubai , vol.1 , pp. 150-185
    • Park, T.1    Kim, Y.2
  • 17
    • 19544372470 scopus 로고    scopus 로고
    • Characterization of antioxidant compounds in aqueous coriander extract Coriandrum sativum L.)
    • de Almeida ME, Mancini Filho J, Barbosa Guerra N. Characterization of antioxidant compounds in aqueous coriander extract Coriandrum sativum L.). LWT-Food Sci Technol. 2005;38:15-9.
    • (2005) LWT-Food Sci Technol , vol.38 , pp. 15-19
    • De Almeida, M.E.1    Mancini Filho, J.2    Barbosa Guerra, N.3
  • 18
    • 33646145080 scopus 로고    scopus 로고
    • Antihypertensive effect of quercetin in rats fed with a high-fat high-sucrose diet
    • 1:CAS:528:DC%2BD28Xks1SgsL8%3D 16636461
    • Yamamoto Y, Oue E. Antihypertensive effect of quercetin in rats fed with a high-fat high-sucrose diet. Biosci Biotechnol Biochem. 2006;70:933-9.
    • (2006) Biosci Biotechnol Biochem , vol.70 , pp. 933-939
    • Yamamoto, Y.1    Oue, E.2
  • 19
    • 50649107938 scopus 로고    scopus 로고
    • Quercetin ameliorates metabolic syndrome and improves the inflammatory status in obese Zucker rats
    • 1:CAS:528:DC%2BD1cXhtVGgtL3F 18551111
    • Rivera L, Morón R, Sánchez M, Zarzuelo A, Galisteo M. Quercetin ameliorates metabolic syndrome and improves the inflammatory status in obese Zucker rats. Obesity. 2008;16:2081-7.
    • (2008) Obesity , vol.16 , pp. 2081-2087
    • Rivera, L.1    Morón, R.2    Sánchez, M.3    Zarzuelo, A.4    Galisteo, M.5
  • 20
    • 37849002920 scopus 로고    scopus 로고
    • Extraction, separation, and detection methods for phenolic acids and flavonoids
    • 1:CAS:528:DC%2BD1cXmt1Gquw%3D%3D 18069740
    • Stalikas CD. Extraction, separation, and detection methods for phenolic acids and flavonoids. J Sep Sci. 2007;30:3268-95.
    • (2007) J Sep Sci , vol.30 , pp. 3268-3295
    • Stalikas, C.D.1
  • 21
    • 68149124472 scopus 로고    scopus 로고
    • Dietary phenolics: Chemistry, bioavailability and effects on health
    • 1:CAS:528:DC%2BD1MXptFGmsr8%3D 19636448
    • Crozier A, Jaganath IB, Clifford MN. Dietary phenolics: chemistry, bioavailability and effects on health. Nat Prod Rep. 2009;26:1001-43.
    • (2009) Nat Prod Rep , vol.26 , pp. 1001-1043
    • Crozier, A.1    Jaganath, I.B.2    Clifford, M.N.3
  • 23
    • 59849124605 scopus 로고    scopus 로고
    • Phenolic compounds rutin and o-coumaric acid ameliorate obesity induced by high-fat diet in rats
    • 1:CAS:528:DC%2BD1MXpsFOq 19119847
    • Hsu C-L, Wu C-H, Huang S-L, Yen G-C. Phenolic compounds rutin and o-coumaric acid ameliorate obesity induced by high-fat diet in rats. J Agric Food Chem. 2009;57:425-31.
    • (2009) J Agric Food Chem , vol.57 , pp. 425-431
    • Hsu, C.-L.1    Wu, C.-H.2    Huang, S.-L.3    Yen, G.-C.4
  • 24
    • 44949127129 scopus 로고    scopus 로고
    • Alkaloid biosynthesis: Metabolism and trafficking
    • 1:CAS:528:DC%2BD1cXntFaqtrs%3D 18251710
    • Ziegler J, Facchini PJ. Alkaloid biosynthesis: metabolism and trafficking. Annu Rev Plant Biol. 2008;59:735-69.
    • (2008) Annu Rev Plant Biol , vol.59 , pp. 735-769
    • Ziegler, J.1    Facchini, P.J.2
  • 25
    • 38349006242 scopus 로고    scopus 로고
    • Berberine improves glucose metabolism through induction of glycolysis
    • 1:CAS:528:DC%2BD1cXhtVansL4%3D 2464622 17971514
    • Yin J, Gao Z, Liu D, Liu Z, Ye J. Berberine improves glucose metabolism through induction of glycolysis. Am J Physiol-Endocrinol Metab. 2008;294:E148-56.
    • (2008) Am J Physiol-Endocrinol Metab , vol.294 , pp. E148-E156
    • Yin, J.1    Gao, Z.2    Liu, D.3    Liu, Z.4    Ye, J.5
  • 26
    • 65649089100 scopus 로고    scopus 로고
    • Berberine improves lipid dysregulation in obesity by controlling central and peripheral AMPK activity
    • 1:CAS:528:DC%2BD1MXkvVyhtLo%3D 19176354
    • Kim WS, Lee YS, Cha SH, Jeong HW, Choe SS, Lee M-R, et al. Berberine improves lipid dysregulation in obesity by controlling central and peripheral AMPK activity. Am J Physiol-Endocrinol Metab. 2009;296:E812-9.
    • (2009) Am J Physiol-Endocrinol Metab , vol.296 , pp. E812-E819
    • Kim, W.S.1    Lee, Y.S.2    Cha, S.H.3    Jeong, H.W.4    Choe, S.S.5    Lee, M.-R.6
  • 27
    • 0020680990 scopus 로고
    • A peroxidase-coupled method for the colorimetric determination of serum triglycerides
    • 1:CAS:528:DyaL3sXhsFOhtLo%3D 6825269
    • McGowan MW, Artiss JD, Strandbergh DR, Zak B. A peroxidase-coupled method for the colorimetric determination of serum triglycerides. Clin Chem. 1983;29:538-42.
    • (1983) Clin Chem , vol.29 , pp. 538-542
    • McGowan, M.W.1    Artiss, J.D.2    Strandbergh, D.R.3    Zak, B.4
  • 28
    • 0016373654 scopus 로고
    • Enzymatic determination of total serum cholesterol
    • 1:CAS:528:DyaE2cXkt1arsL8%3D 4818200
    • Allain CC, Poon LS, Chan CS, Richmond W, Fu PC. Enzymatic determination of total serum cholesterol. Clin Chem. 1974;20:470-5.
    • (1974) Clin Chem , vol.20 , pp. 470-475
    • Allain, C.C.1    Poon, L.S.2    Chan, C.S.3    Richmond, W.4    Fu, P.C.5
  • 29
    • 0015348189 scopus 로고
    • Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge
    • 1:CAS:528:DyaE38Xkslagsbw%3D 4337382
    • Friedewald WT, Levy RI, Fredrickson DS. Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. Clin Chem. 1972;18:499-502.
    • (1972) Clin Chem , vol.18 , pp. 499-502
    • Friedewald, W.T.1    Levy, R.I.2    Fredrickson, D.S.3
  • 30
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipids from animal tissues
    • 1:STN:280:DyaG2s%2FnsFCjtw%3D%3D 13428781
    • Folch J, Lees M, Sloane-Stanley G. A simple method for the isolation and purification of total lipids from animal tissues. J Biol Chem. 1957;226:497-509.
    • (1957) J Biol Chem , vol.226 , pp. 497-509
    • Folch, J.1    Lees, M.2    Sloane-Stanley, G.3
  • 31
    • 0016317313 scopus 로고
    • Genetic and developmental control of multiple forms of L-glycerol 3-phosphate dehydrogenase
    • 1:CAS:528:DyaE2MXntVymsQ%3D%3D 4430673
    • Kozak LP, Jensen JT. Genetic and developmental control of multiple forms of L-glycerol 3-phosphate dehydrogenase. J Biol Chem. 1974;249:7775-81.
    • (1974) J Biol Chem , vol.249 , pp. 7775-7781
    • Kozak, L.P.1    Jensen, J.T.2
  • 33
    • 84856841394 scopus 로고    scopus 로고
    • Thymoquinone ameliorates the immunological and histological changes induced by exposure to imidacloprid insecticide
    • Mohany M, El-Feki M, Refaat I, Garraud O, Badr G: Thymoquinone ameliorates the immunological and histological changes induced by exposure to imidacloprid insecticide. J Toxicol Sci. 2012;37(1):1-11.
    • (2012) J Toxicol Sci , vol.37 , Issue.1 , pp. 1-11
    • Mohany, M.1    El-Feki, M.2    Refaat, I.3    Garraud, O.4    Badr, G.5
  • 34
    • 84912083293 scopus 로고    scopus 로고
    • A review on the models of obesity and metabolic syndrome in rats
    • Angelova P, Boyadjiev N. A review on the models of obesity and metabolic syndrome in rats. Trakia J Sci. 2013;11:5.
    • (2013) Trakia J Sci , vol.11 , pp. 5
    • Angelova, P.1    Boyadjiev, N.2
  • 35
    • 42949178968 scopus 로고    scopus 로고
    • Alterations in hepatic mitochondrial compartment in a model of obesity and insulin resistance
    • 18277391
    • Raffaella C, Francesca B, Italia F, Marina P, Giovanna L, Susanna I. Alterations in hepatic mitochondrial compartment in a model of obesity and insulin resistance. Obesity. 2008;16:958-64.
    • (2008) Obesity , vol.16 , pp. 958-964
    • Raffaella, C.1    Francesca, B.2    Italia, F.3    Marina, P.4    Giovanna, L.5    Susanna, I.6
  • 36
    • 84872797265 scopus 로고    scopus 로고
    • Modified high-sucrose diet-induced abdominally obese and normal-weight rats developed high plasma free Fatty Acid and insulin resistance
    • Cao L, Liu X, Cao H, Lv Q, Tong N. Modified high-sucrose diet-induced abdominally obese and normal-weight rats developed high plasma free Fatty Acid and insulin resistance. Oxid Med Cell Longev. 2012;2012:374346.
    • (2012) Oxid Med Cell Longev , vol.2012
    • Cao, L.1    Liu, X.2    Cao, H.3    Lv, Q.4    Tong, N.5
  • 38
    • 76749122292 scopus 로고    scopus 로고
    • Chlorogenic acid exhibits anti-obesity property and improves lipid metabolism in high-fat diet-induced-obese mice
    • 1:CAS:528:DC%2BC3cXit1Orur8%3D 20064576
    • Cho A-S, Jeon S-M, Kim M-J, Yeo J, Seo K-I, Choi M-S, et al. Chlorogenic acid exhibits anti-obesity property and improves lipid metabolism in high-fat diet-induced-obese mice. Food Chem Toxicol. 2010;48:937-43.
    • (2010) Food Chem Toxicol , vol.48 , pp. 937-943
    • Cho, A.-S.1    Jeon, S.-M.2    Kim, M.-J.3    Yeo, J.4    Seo, K.-I.5    Choi, M.-S.6
  • 39
    • 0141958066 scopus 로고    scopus 로고
    • Effects of a high-sucrose diet on body weight, plasma triglycerides, and stress tolerance
    • 12828189
    • Kanazawa M, Xue CY, Kageyama H, Suzuki E, Ito R, Namba Y, et al. Effects of a high-sucrose diet on body weight, plasma triglycerides, and stress tolerance. Nutr Rev. 2003;61:S27-33.
    • (2003) Nutr Rev , vol.61 , pp. S27-S33
    • Kanazawa, M.1    Xue, C.Y.2    Kageyama, H.3    Suzuki, E.4    Ito, R.5    Namba, Y.6
  • 40
    • 84884937949 scopus 로고    scopus 로고
    • Berberine reverts hepatic mitochondrial dysfunction in high-fat fed rats: A possible role for SirT3 activation
    • 1:CAS:528:DC%2BC3sXhslaitbvE 24041461
    • Teodoro JS, Duarte FV, Gomes AP, Varela AT, Peixoto FM, Rolo AP, et al. Berberine reverts hepatic mitochondrial dysfunction in high-fat fed rats: a possible role for SirT3 activation. Mitochondrion. 2013;13:637-46.
    • (2013) Mitochondrion , vol.13 , pp. 637-646
    • Teodoro, J.S.1    Duarte, F.V.2    Gomes, A.P.3    Varela, A.T.4    Peixoto, F.M.5    Rolo, A.P.6
  • 41
    • 84889251201 scopus 로고    scopus 로고
    • Flaxseed and quercetin improves anti-inflammatory cytokines level and insulin sensitivity in animal model of metabolic syndrome fructose-fed rats
    • Abdelkarem HM, Fadda LH. Flaxseed and quercetin improves anti-inflammatory cytokines level and insulin sensitivity in animal model of metabolic syndrome fructose-fed rats. Afr J Pharm Pharmacol. 2013;7:2452-8.
    • (2013) Afr J Pharm Pharmacol , vol.7 , pp. 2452-2458
    • Abdelkarem, H.M.1    Fadda, L.H.2
  • 42
    • 33745948316 scopus 로고    scopus 로고
    • Antihyperglycemic and antioxidant properties of caffeic acid in db/db mice
    • 1:CAS:528:DC%2BD28XnslOls78%3D 16644902
    • Jung UJ, Lee M-K, Park YB, Jeon S-M, Choi M-S. Antihyperglycemic and antioxidant properties of caffeic acid in db/db mice. J Pharmacol Exp Ther. 2006;318:476-83.
    • (2006) J Pharmacol Exp Ther , vol.318 , pp. 476-483
    • Jung, U.J.1    Lee, M.-K.2    Park, Y.B.3    Jeon, S.-M.4    Choi, M.-S.5
  • 43
    • 66349088529 scopus 로고    scopus 로고
    • Hepatic triacylglycerol accumulation and insulin resistance
    • 2674743 18997164
    • Nagle CA, Klett EL, Coleman RA. Hepatic triacylglycerol accumulation and insulin resistance. J Lipid Res. 2009;50:S74-9.
    • (2009) J Lipid Res , vol.50 , pp. S74-S79
    • Nagle, C.A.1    Klett, E.L.2    Coleman, R.A.3
  • 44
    • 84863208496 scopus 로고    scopus 로고
    • Diet high in fat and sucrose induces rapid onset of obesity-related metabolic syndrome partly through rapid response of genes involved in lipogenesis, insulin signalling and inflammation in mice
    • 1:CAS:528:DC%2BC38XhslOiu7bE 3407732 22762794
    • Yang Z-H, Miyahara H, Takeo J, Katayama M. Diet high in fat and sucrose induces rapid onset of obesity-related metabolic syndrome partly through rapid response of genes involved in lipogenesis, insulin signalling and inflammation in mice. Diabetol Metab Syndr. 2012;4:32.
    • (2012) Diabetol Metab Syndr , vol.4 , pp. 32
    • Yang, Z.-H.1    Miyahara, H.2    Takeo, J.3    Katayama, M.4
  • 45
    • 84878366989 scopus 로고    scopus 로고
    • The effects of chronic AMPK activation on hepatic triglyceride accumulation and glycerol 3-phosphate acyltransferase activity with high fat feeding
    • 1:CAS:528:DC%2BC3sXhtVWksb%2FM 3679947 23725555
    • Henriksen BS, Curtis ME, Fillmore N, Cardon BR, Thomson DM, Hancock CR. The effects of chronic AMPK activation on hepatic triglyceride accumulation and glycerol 3-phosphate acyltransferase activity with high fat feeding. Diabetol Metab Syndr. 2013;5:29.
    • (2013) Diabetol Metab Syndr , vol.5 , pp. 29
    • Henriksen, B.S.1    Curtis, M.E.2    Fillmore, N.3    Cardon, B.R.4    Thomson, D.M.5    Hancock, C.R.6
  • 46
    • 79955672715 scopus 로고    scopus 로고
    • Anti-metabolic syndrome and immunostimulant activities of Egyptian fenugreek seeds in diabetic/obese and immunosuppressive rat models
    • 1:CAS:528:DC%2BC3MXivFyntL8%3D 21205429
    • Ramadan G, El-Beih NM, Abd El-Kareem HF. Anti-metabolic syndrome and immunostimulant activities of Egyptian fenugreek seeds in diabetic/obese and immunosuppressive rat models. Br J Nutr. 2011;105:995-1004.
    • (2011) Br J Nutr , vol.105 , pp. 995-1004
    • Ramadan, G.1    El-Beih, N.M.2    Abd El-Kareem, H.F.3
  • 47
    • 84938342171 scopus 로고    scopus 로고
    • Is there any role of glucose-6-phosphate dehydrogenase in obesity induced metabolic disorder
    • 1:CAS:528:DC%2BC2MXlsVClsrc%3D
    • Sankhla M, Mathur K, Rathor JS. Is there any role of glucose-6-phosphate dehydrogenase in obesity induced metabolic disorder. Health. 2012;4:1530.
    • (2012) Health , vol.4 , pp. 1530
    • Sankhla, M.1    Mathur, K.2    Rathor, J.S.3
  • 48
    • 78651354134 scopus 로고    scopus 로고
    • Protective effect of Garcinia against renal oxidative stress and biomarkers induced by high fat and sucrose diet
    • 1:CAS:528:DC%2BC3MXhtFOgsLg%3D 3034692 21235803
    • Amin KA, Kamel HH, Eltawab MAA. Protective effect of Garcinia against renal oxidative stress and biomarkers induced by high fat and sucrose diet. Lipids Health Dis. 2011;10:6.
    • (2011) Lipids Health Dis , vol.10 , pp. 6
    • Amin, K.A.1    Kamel, H.H.2    Eltawab, M.A.A.3
  • 49
    • 0002316655 scopus 로고    scopus 로고
    • Familial lipoprotein lipase deficiency, Apo C-II deficiency, and hepatic lipase deficiency
    • BJaD SS. Familial lipoprotein lipase deficiency, Apo C-II deficiency, and hepatic lipase deficiency. In: The metabolic and molecular bases of inherited disease. 2001. p. 2789-816.
    • (2001) The Metabolic and Molecular Bases of Inherited Disease , pp. 2789-2816
    • Bjad, S.S.1
  • 50
    • 2942683422 scopus 로고    scopus 로고
    • Abdominal obesity and dyslipidemia in the metabolic syndrome: Importance of type 2 diabetes and familial combined hyperlipidemia in coronary artery disease risk
    • 1:CAS:528:DC%2BD2cXmtlGqtL0%3D 15181030
    • Carr MC, Brunzell JD. Abdominal obesity and dyslipidemia in the metabolic syndrome: importance of type 2 diabetes and familial combined hyperlipidemia in coronary artery disease risk. J Clin Endocrinol Metab. 2004;89:2601-7.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 2601-2607
    • Carr, M.C.1    Brunzell, J.D.2
  • 52
    • 77954427050 scopus 로고    scopus 로고
    • The effects of a fat-and sugar-enriched diet and chronic stress on nonalcoholic fatty liver disease in male Wistar rats
    • J-h F, Sun H-s, Wang Y, Zheng W-q, Shi Z-y, Wang Q-j. The effects of a fat-and sugar-enriched diet and chronic stress on nonalcoholic fatty liver disease in male Wistar rats. Dig Dis Sci. 2010;55:2227-36.
    • (2010) Dig Dis Sci , vol.55 , pp. 2227-2236
    • J-H, F.1    Sun, H.-S.2    Wang, Y.3    Zheng, W.-Q.4    Shi, Z.-Y.5    Wang, Q.-J.6
  • 53
    • 80052548067 scopus 로고    scopus 로고
    • Redox homeostasis and posttranslational modifications/activity of phosphatase and tensin homolog in hepatocytes from rats with diet-induced hepatosteatosis
    • 1:CAS:528:DC%2BC38XlsVyjsg%3D%3D 21454064
    • Alisi A, Bruscalupi G, Pastore A, Petrini S, Panera N, Massimi M, et al. Redox homeostasis and posttranslational modifications/activity of phosphatase and tensin homolog in hepatocytes from rats with diet-induced hepatosteatosis. J Nutr Biochem. 2012;23:169-78.
    • (2012) J Nutr Biochem , vol.23 , pp. 169-178
    • Alisi, A.1    Bruscalupi, G.2    Pastore, A.3    Petrini, S.4    Panera, N.5    Massimi, M.6
  • 54
    • 80053572802 scopus 로고    scopus 로고
    • Berberine reducing insulin resistance by up-regulating IRS-2 mRNA expression in nonalcoholic fatty liver disease (NAFLD) rat liver
    • 1:CAS:528:DC%2BC3MXht1Gru7%2FO 21839075
    • Xing L-J, Zhang L, Liu T, Hua Y-Q, Zheng P-Y, Ji G. Berberine reducing insulin resistance by up-regulating IRS-2 mRNA expression in nonalcoholic fatty liver disease (NAFLD) rat liver. Eur J Pharmacol. 2011;668:467-71.
    • (2011) Eur J Pharmacol , vol.668 , pp. 467-471
    • Xing, L.-J.1    Zhang, L.2    Liu, T.3    Hua, Y.-Q.4    Zheng, P.-Y.5    Ji, G.6
  • 55
    • 84938305784 scopus 로고    scopus 로고
    • Hypolipidemic and antioxidant ef fects of phytochemical compounds against hepatic steatosis induced by high fat high sucrose diet in rats
    • Ragab SMM, Omar HM, Sary K, Abd Elghaffar SK, El-Metwally TH. Hypolipidemic and antioxidant ef fects of phytochemical compounds against hepatic steatosis induced by high fat high sucrose diet in rats. Arch Biomed Sci. 2014;2(1):1-10.
    • (2014) Arch Biomed Sci , vol.2 , Issue.1 , pp. 1-10
    • Ragab, S.M.M.1    Omar, H.M.2    Sary, K.3    Abd Elghaffar, S.K.4    El-Metwally, T.H.5
  • 56
    • 28944446431 scopus 로고    scopus 로고
    • The many faces of PPARγ
    • 1:CAS:528:DC%2BD28XptVOj 16360030
    • Lehrke M, Lazar MA. The many faces of PPARγ. Cell. 2005;123:993-9.
    • (2005) Cell , vol.123 , pp. 993-999
    • Lehrke, M.1    Lazar, M.A.2
  • 57
    • 77958025377 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor γ: Innate protection from excessive fibrogenesis and potential therapeutic target in systemic sclerosis
    • 1:CAS:528:DC%2BC3cXht1ahu7jK 20693905
    • Wei J, Bhattacharyya S, Varga J. Peroxisome proliferator-activated receptor γ: innate protection from excessive fibrogenesis and potential therapeutic target in systemic sclerosis. Curr Opin Rheumatol. 2010;22:671-6.
    • (2010) Curr Opin Rheumatol , vol.22 , pp. 671-676
    • Wei, J.1    Bhattacharyya, S.2    Varga, J.3
  • 58
    • 79956072587 scopus 로고    scopus 로고
    • Berberine attenuates cardiac dysfunction in hyperglycemic and hypercholesterolemic rats
    • 1:CAS:528:DC%2BC3MXmtFamsr4%3D 21458442
    • Dong S-F, Hong Y, Liu M, Hao Y-Z, Yu H-S, Liu Y, et al. Berberine attenuates cardiac dysfunction in hyperglycemic and hypercholesterolemic rats. Eur J Pharmacol. 2011;660:368-74.
    • (2011) Eur J Pharmacol , vol.660 , pp. 368-374
    • Dong, S.-F.1    Hong, Y.2    Liu, M.3    Hao, Y.-Z.4    Yu, H.-S.5    Liu, Y.6
  • 59
    • 47849123027 scopus 로고    scopus 로고
    • Effects of Momordica charantia on insulin resistance and visceral obesity in mice on high-fat diet
    • 1:CAS:528:DC%2BD1cXptVKnsrc%3D 18550200
    • Shih C-C, Lin C-H, Lin W-L. Effects of Momordica charantia on insulin resistance and visceral obesity in mice on high-fat diet. Diabetes Res Clin Pract. 2008;81:134-43.
    • (2008) Diabetes Res Clin Pract , vol.81 , pp. 134-143
    • Shih, C.-C.1    Lin, C.-H.2    Lin, W.-L.3
  • 60
    • 39849099238 scopus 로고    scopus 로고
    • Role of peroxisome proliferators-activated receptors in the pathogenesis and treatment of nonalcoholic fatty liver disease
    • 1:CAS:528:DC%2BD1cXjsFykt78%3D 2673387 18176957
    • Kallwitz ER, McLachlan A, Cotler SJ. Role of peroxisome proliferators-activated receptors in the pathogenesis and treatment of nonalcoholic fatty liver disease. World J Gastroenterol. 2008;14(1):22-8.
    • (2008) World J Gastroenterol , vol.14 , Issue.1 , pp. 22-28
    • Kallwitz, E.R.1    McLachlan, A.2    Cotler, S.J.3
  • 61
    • 78049235146 scopus 로고    scopus 로고
    • Berberine regulates peroxisome proliferator-activated receptors and positive transcription elongation factor b expression in diabetic adipocytes
    • 1:CAS:528:DC%2BC3cXhtlKktbvL 20868663
    • Zhou J, Zhou S. Berberine regulates peroxisome proliferator-activated receptors and positive transcription elongation factor b expression in diabetic adipocytes. Eur J Pharmacol. 2010;649:390-7.
    • (2010) Eur J Pharmacol , vol.649 , pp. 390-397
    • Zhou, J.1    Zhou, S.2
  • 62
    • 46749104743 scopus 로고    scopus 로고
    • Dietary conjugated linoleic acid increases PPARγ gene expression in adipose tissue of obese rat, and improves insulin resistance
    • 1:CAS:528:DC%2BD1cXosVOntL8%3D 18304850
    • Zhou X-R, Sun C-H, Liu J-R, Zhao D. Dietary conjugated linoleic acid increases PPARγ gene expression in adipose tissue of obese rat, and improves insulin resistance. Growth Horm IGF Res. 2008;18:361-8.
    • (2008) Growth Horm IGF Res , vol.18 , pp. 361-368
    • Zhou, X.-R.1    Sun, C.-H.2    Liu, J.-R.3    Zhao, D.4
  • 63
    • 84875531061 scopus 로고    scopus 로고
    • Camel whey protein enhances diabetic wound healing in a streptozotocin-induced diabetic mouse model: The critical role of β-Defensin-1,-2 and-3
    • 1:CAS:528:DC%2BC3sXnvFajsrs%3D 3622574 23547923
    • Badr G. Camel whey protein enhances diabetic wound healing in a streptozotocin-induced diabetic mouse model: the critical role of β-Defensin-1,-2 and-3. Lipids Health Dis. 2013;12(1):46.
    • (2013) Lipids Health Dis , vol.12 , Issue.1 , pp. 46
    • Badr, G.1
  • 64
    • 84859909661 scopus 로고    scopus 로고
    • Supplementation with undenatured whey protein during diabetes mellitus improves the healing and closure of diabetic wounds through the rescue of functional long-lived wound macrophages
    • 1:CAS:528:DC%2BC38Xls12isLY%3D 22508064
    • Badr G. Supplementation with undenatured whey protein during diabetes mellitus improves the healing and closure of diabetic wounds through the rescue of functional long-lived wound macrophages. Cell Physiol Biochem. 2012;29:571-82.
    • (2012) Cell Physiol Biochem , vol.29 , pp. 571-582
    • Badr, G.1
  • 65
    • 84882946462 scopus 로고    scopus 로고
    • Enhanced anticancer efficacy of snake venom combined with silica nanoparticles in a murine model of human multiple myeloma: Molecular targets for cell cycle arrest and apoptosis induction
    • Al-Sadoon MK, Rabah DM, Badr G. Enhanced anticancer efficacy of snake venom combined with silica nanoparticles in a murine model of human multiple myeloma: molecular targets for cell cycle arrest and apoptosis induction. Cell Immunol. 2013;284:129-38.
    • (2013) Cell Immunol , vol.284 , pp. 129-138
    • Al-Sadoon, M.K.1    Rabah, D.M.2    Badr, G.3
  • 66
    • 83455203366 scopus 로고    scopus 로고
    • Thymoquinone decreases F-actin polymerization and proliferation of human multiple myeloma cells through suppression of STAT3 phosphorylation and Bcl2/Bcl-XL expression
    • Badr G, Mohany M and Abou-Tarboush F. Thymoquinone decreases F-actin polymerization and proliferation of human multiple myeloma cells through suppression of STAT3 phosphorylation and Bcl2/Bcl-XL expression. Lipids Health Dis. 2011;10(1):236.
    • (2011) Lipids Health Dis , vol.10 , Issue.1 , pp. 236
    • Badr, G.1    Mohany, M.2    Abou-Tarboush, F.3
  • 67
    • 79751525036 scopus 로고    scopus 로고
    • Perinatal Supplementation with Thymoquinone Improves Diabetic Complications and T Cell Immune Responses in Rat Offspring
    • Badr G, Alwasel S, Ebaid H, Mohany M and Alhazza I. Perinatal Supplementation With Thymoquinone Improves Diabetic Complications and T Cell Immune Responses in Rat Offspring. Cell Immunol. 2011;267(2):133-40.
    • (2011) Cell Immunol , vol.267 , Issue.2 , pp. 133-140
    • Badr, G.1    Alwasel, S.2    Ebaid, H.3    Mohany, M.4    Alhazza, I.5
  • 68
    • 84862253299 scopus 로고    scopus 로고
    • Treatment of diabetic mice with undenatured whey protein enhances healing of diabetic wounds through the reduction of pro-inflammatory stimuli and modulation of the expression of MIP-1α, MIP-2, CX3CL1 and TGF-β
    • Badr G, Mohany M, Badr BM, Mahmoud MH, Rabah DM, Garraud O. Treatment of diabetic mice with undenatured whey protein enhances healing of diabetic wounds through the reduction of pro-inflammatory stimuli and modulation of the expression of MIP-1α, MIP-2, CX3CL1 and TGF-β. BMC Immunol. 2012;13(1):32.
    • (2012) BMC Immunol , vol.13 , Issue.1 , pp. 32
    • Badr, G.1    Mohany, M.2    Badr, B.M.3    Mahmoud, M.H.4    Rabah, D.M.5    Garraud, O.6
  • 69
    • 84869096359 scopus 로고    scopus 로고
    • Modulation of immune cell proliferation and chemotaxis towards CC chemokine ligand (CCL)-21 and CXC chemokine ligand (CXCL)-12 in un-denatured whey protein-treated mice
    • Badr G, Ebaid H, Mohany M and Abu el-saad A: Modulation of immune cell proliferation and chemotaxis towards CC chemokine ligand (CCL)-21 and CXC chemokine ligand (CXCL)-12 in un-denatured whey protein-treated mice. J Nutr Biochem. 2012;23(12):1640-6.
    • (2012) J Nutr Biochem , vol.23 , Issue.12 , pp. 1640-1646
    • Badr, G.1    Ebaid, H.2    Mohany, M.3    Abu El-Saad, A.4
  • 70
    • 84856011783 scopus 로고    scopus 로고
    • Samsum Ant Venom Induces Apoptosis in MCF-7 Human Breast Carcinoma Cells and Inhibits IGF-1-mediaed Proliferation through PI3K/AKT and ERK Signaling Pathways
    • Badr G, Garraud O, Daghestani M, Al-Khalifa M and Richard Y: Samsum Ant Venom Induces Apoptosis in MCF-7 Human Breast Carcinoma Cells and Inhibits IGF-1-mediaed Proliferation through PI3K/AKT and ERK Signaling Pathways. Cell Immunol. 2012;273(1):10-6.
    • (2012) Cell Immunol , vol.273 , Issue.1 , pp. 10-16
    • Badr, G.1    Garraud, O.2    Daghestani, M.3    Al-Khalifa, M.4    Richard, Y.5


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