Genome analysis of the first extensively drug-resistant (XDR) Mycobacterium tuberculosis in Malaysia provides insights into the genetic basis of its biology and drug resistance

PLoS ONE

Volumn 10, Issue 6, 2015, Pages

  Kuan, Chee Sian ^a   Chan, Chai Ling ^a   Yew, Su Mei ^a   Toh, Yue Fen ^a   Khoo, Jia Shiun ^b   Chong, Jennifer ^a   Lee, Kok Wei ^b   Tan, Yung Chie ^b   Yee, Wai Yan ^b   Ngeow, Yun Fong ^a   Ng, Kee Peng ^a  

^a UNIVERSITY OF MALAYA   (Malaysia)

^b Codon Genomics SB Seri Kembangan ^*  (Malaysia)

Author keywords

[No Author keywords available]

Indexed keywords

AMIKACIN; CAPREOMYCIN; CIPROFLOXACIN; ETHAMBUTOL; ETHIONAMIDE; ISONIAZID; KANAMYCIN; OFLOXACIN; RIFAMPICIN; SALICYLIC ACID; STREPTOMYCIN; TUBERCULOSTATIC AGENT;

ACRR GENE; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL CELL WALL; BACTERIAL GENE; BACTERIAL GENOME; BACTERIAL STRAIN; COMPUTER MODEL; CONTROLLED STUDY; EMBA GENE; EXTENSIVELY DRUG RESISTANT TUBERCULOSIS; FADD GENE; FADD28 GENE; GENE MUTATION; GENE SEQUENCE; GENOME ANALYSIS; MALAYSIA; MMPL GENE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; NUOD GENE; PHYLOGENY; PKS GENE; PKS7 GENE; PROMOTER REGION; SINGLE NUCLEOTIDE POLYMORPHISM; TETR GENE; GENE EXPRESSION PROFILING; GENETICS; HUMAN; ISOLATION AND PURIFICATION; MALE; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; MIDDLE AGED; MULTIDRUG RESISTANCE; PATHOGENICITY;

MYCOBACTERIUM TUBERCULOSIS;

ANTITUBERCULAR AGENTS; DRUG RESISTANCE, MULTIPLE, BACTERIAL; EXTENSIVELY DRUG-RESISTANT TUBERCULOSIS; GENE EXPRESSION PROFILING; GENOME, BACTERIAL; HUMANS; MALAYSIA; MALE; MICROBIAL SENSITIVITY TESTS; MIDDLE AGED; MYCOBACTERIUM TUBERCULOSIS; PHYLOGENY; POLYMORPHISM, SINGLE NUCLEOTIDE;

EID: 84938349050     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0131694     Document Type: Article

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