Molecular characterization of amikacin, kanamycin and capreomycin resistance in M/XDR-TB strains isolated in Thailand

BMC Microbiology

Volumn 14, Issue 1, 2014, Pages

  Sowajassatakul, Angkanang ^a   Prammananan, Therdsak ^b,d   Chaiprasert, Angkana ^c,d   Phunpruch, Saranya ^a  

^a KING MONGKUT'S INSTITUTE OF TECHNOLOGY LADKRABANG   (Thailand)

^b NATIONAL SCIENCE AND TECHNOLOGY DEVELOPMENT AGENCY   (Thailand)

^c MAHIDOL UNIVERSITY   (Thailand)

^d Siriraj Foundation   (Thailand)

Author keywords

Aminoglycoside; Resistance; Second line drug; Tuberculosis

Indexed keywords

AMIKACIN; AMINO ACID; CAPREOMYCIN; KANAMYCIN; OFLOXACIN;

ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; DRUG ISOLATION; EXTENSIVELY DRUG RESISTANT TUBERCULOSIS; FRAMESHIFT MUTATION; GENOTYPE; MINIMUM INHIBITORY CONCENTRATION; MULTIDRUG RESISTANT TUBERCULOSIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; POINT MUTATION; PROMOTER REGION; SEQUENCE ANALYSIS; SPUTUM SMEAR; STOP CODON; THAILAND;

MYCOBACTERIUM TUBERCULOSIS;

AMIKACIN; ANTITUBERCULAR AGENTS; BACTERIAL PROTEINS; CAPREOMYCIN; DRUG RESISTANCE, MULTIPLE, BACTERIAL; EXTENSIVELY DRUG-RESISTANT TUBERCULOSIS; HUMANS; KANAMYCIN; MYCOBACTERIUM TUBERCULOSIS; POINT MUTATION; SPUTUM; THAILAND;

EID: 84902755906     PISSN: None     EISSN: 14712180     Source Type: Journal    
DOI: 10.1186/1471-2180-14-165     Document Type: Article

References (43)

1. WHO, Global tuberculosis report 2013 WHO/HTM/TB/2013.11. Geneva. 2013
2. Evaluation of the analytical performance of the Xpert MTB/RIF assay. Blakemore R, Story E, Helb D, Kop J, Banada P, Owens MR, Chakravorty S, Jones M, Alland D, J Clin Microbiol 2010 48 7 2495 2501 10.1128/JCM.00128-10 20504986
3. Rapid molecular detection of tuberculosis and rifampin resistance. Boehme CC, Nabeta P, Hillemann D, Nicol MP, Shenai S, Krapp F, Allen J, Tahirli R, Blakemore R, Rustomjee R, Milovic A, Jones M, O'Brien SM, Persing DH, Ruesch-Gerdes S, Gotuzzo E, Rodrigues C, Alland D, Perkins MD, N Engl J Med 2010 363 11 1005 1015 10.1056/NEJMoa0907847 20825313
4. Rapid detection of Mycobacterium tuberculosis and rifampin resistance by use of on-demand, near-patient technology. Helb D, Jones M, Story E, Boehme C, Wallace E, Ho K, Kop J, Owens MR, Rodgers R, Banada P, Safi H, Blakemore R, Lan NTN, Jones-Lpez EC, Levi M, Burday M, Ayakaka I, Mugerwa RD, McMillan B, Winn-Deen E, Christel L, Dailey P, Perkins MD, Persing DH, Alland D, J Clin Microbiol 2010 48 1 229 237 10.1128/JCM.01463-09 19864480
5. Evaluation of the GenoType MTBDRplus assay for rifampin and isoniazid susceptibility testing of Mycobacterium tuberculosis strains and clinical specimens. Hillemann D, Rüsch-Gerdes S, Richter E, J Clin Microbiol 2007 45 8 2635 2640 10.1128/JCM.00521-07 17537937 (Pubitemid 47295497)
6. Evaluation of the GenoType® MTBDRplus assay and identification of a rare mutation for improving MDR-TB detection. Jin J, Zhang Y, Fan X, Diao N, Shao L, Wang F, Hu P, Wang S, Weng X, Zhang W, Int J Tuberc Lung Dis 2012 16 4 521 526 10.5588/ijtld.11.0269 22325117
7. GenoType MTBDRplus assay for molecular detection of rifampin and isoniazid resistance in Mycobacterium tuberculosis strains and clinical samples. Lacoma A, Garcia-Sierra N, Prat C, Ruiz-Manzano J, Haba L, Rosés S, Maldonado J, Domínguez J, J Clin Microbiol 2008 46 11 3660 3667 10.1128/JCM.00618-08 18784319
8. Basis for prokaryotic specificity of action of aminoglycoside antibiotics. Recht MI, Douthwaite S, Puglisi JD, EMBO J 1999 18 11 3133 3138 10.1093/emboj/18.11.3133 10357824 (Pubitemid 29255621)
9. Mutation detection and accurate diagnosis of extensively drug-resistant tuberculosis: report from a tertiary care center in India. Ajbani K, Rodrigues C, Shenai S, Mehta A, J Clin Microbiol 2011 49 4 1588 1590 10.1128/JCM.00113-11 21289142
10. Novel multiplex allele-specific PCR assays for the detection of resistance to second-line drugs in Mycobacterium tuberculosis. Evans J, Segal H, J Antimicrob Chemother 2010 65 5 897 900 10.1093/jac/dkq047 20185419
11. Genetic analysis of extensively drug-resistant Mycobacterium tuberculosis strains in Lisbon, Portugal. Perdigão J, Macedo R, Malaquias A, Ferreira A, Brum L, Portugal I, J Antimicrob Chemother 2010 65 2 224 227 10.1093/jac/dkp452 20028780
12. Molecular characterization of multidrug- and extensively drug-resistant Mycobacterium tuberculosis strains in Jiangxi, China. Yuan X, Zhang T, Kawakami K, Zhu J, Li H, Lei J, Tu S, J Clin Microbiol 2012 50 7 2404 2413 10.1128/JCM.06860-11 22553245
13. Aminoglycoside cross-resistance in Mycobacterium tuberculosis due to mutations in the 5′ untranslated region of whiB7. Reeves AZ, Campbell PJ, Sultana R, Malik S, Murray M, Plikaytis BB, Shinnick TM, Posey JE, Antimicrob Agents Chemother 2013 57 4 1857 1865 10.1128/AAC.02191-12 23380727
14. Overexpression of the chromosomally encoded aminoglycoside acetyltransferase eis confers kanamycin resistance in Mycobacterium tuberculosis. Zaunbrecher MA, Sikes RD, Metchock B, Shinnick TM, Posey JE, Proc Natl Acad Sci U S A 2009 106 47 20004 20009 10.1073/pnas.0907925106 19906990
15. Molecular detection of mutations associated with first- and second-line drug resistance compared with conventional drug susceptibility testing of Mycobacterium tuberculosis. Campbell PJ, Morlock GP, Sikes RD, Dalton TL, Metchock B, Starks AM, Hooks DP, Cowan LS, Plikaytis BB, Posey JE, Antimicrob Agents Chemother 2011 55 5 2032 2041 10.1128/AAC.01550-10 21300839
16. Comparison of clinical isolates and in vitro selected mutants reveals that tlyA is not a sensitive genetic marker for capreomycin resistance in Mycobacterium tuberculosis. Engström A, Perskvist N, Werngren J, Hoffner SE, Juréen P, J Antimicrob Chemother 2011 66 6 1247 1254 10.1093/jac/dkr109 21427106
17. The role of eis mutations in the development of kanamycin resistance in Mycobacterium tuberculosis isolates from the Moscow region. Gikalo MB, Nosova EY, Krylova LY, Moroz AM, J Antimicrob Chemother 2012 67 9 2107 2109 10.1093/jac/dks178 22593564
18. Molecular cloning and characterization of Tap, a putative multidrug efflux pump present in Mycobacterium fortuitum and Mycobacterium tuberculosis. Aínsa JA, Blokpoel MCJ, Otal I, Young DB, De Smet KAL, Martín C, J Bacteriol 1998 180 22 5836 5843 9811639 (Pubitemid 28514198)
19. Ancestral antibiotic resistance in Mycobacterium tuberculosis. Morris RP, Nguyen L, Gatfield J, Visconti K, Nguyen K, Schnappinger D, Ehrt S, Liu Y, Heifets L, Pieters J, Schoolnik G, Thompson CJ, Proc Natl Acad Sci U S A 2005 102 34 12200 12205 10.1073/pnas.0505446102 16103351 (Pubitemid 41291152)
20. Molecular analysis of cross-resistance to capreomycin, kanamycin, amikacin, and viomycin in Mycobacterium tuberculosis. Maus CE, Plikaytis BB, Shinnick TM, Antimicrob Agents Chemother 2005 49 8 3192 3197 10.1128/AAC.49.8.3192-3197.2005 16048924 (Pubitemid 41060560)
21. Polymorphisms associated with resistance and cross-resistance to aminoglycosides and capreomycin in Mycobacterium tuberculosis isolates from south korean patients with drug-resistant tuberculosis. Via LE, Cho SN, Hwang S, Bang H, Park SK, Kang HS, Jeon D, Min SY, Oh T, Kim Y, Kim YM, Rajan V, Wong SY, Shamputa IC, Carroll M, Goldfeder L, Lee SA, Holland SM, Eum S, Lee H, Barry CE, J Clin Microbiol 2010 48 2 402 411 10.1128/JCM.01476-09 20032248
22. Molecular basis for selectivity of antituberculosis compounds capreomycin and viomycin. Akbergenov R, Shcherbakov D, Matt T, Duscha S, Meyer M, Wilson DN, Böttger EC, Antimicrob Agents Chemother 2011 55 10 4712 4717 10.1128/AAC.00628-11 21768509
23. Capreomycin binds across the ribosomal subunit interface using tlyA-encoded 2′-O-methylations in 16S and 23S rRNAs. Johansen SK, Maus CE, Plikaytis BB, Douthwaite S, Mol Cell 2006 23 2 173 182 10.1016/j.molcel.2006. 05.044 16857584 (Pubitemid 44081881)
24. Mutation of tlyA confers capreomycin resistance in Mycobacterium tuberculosis. Maus CE, Plikaytis BB, Shinnick TM, Antimicrob Agents Chemother 2005 49 2 571 577 10.1128/AAC.49.2.571-577.2005 15673735 (Pubitemid 40175664)
25. Detection by GenoType MTBDRsl test of complex mechanisms of resistance to second-line drugs and ethambutol in multidrug-resistant Mycobacterium tuberculosis complex isolates. Brossier F, Veziris N, Aubry A, Jarlier V, Sougakoff W, J Clin Microbiol 2010 48 5 1683 1689 10.1128/JCM.01947-09 20335420
26. Sequence analyses of just four genes to detect extensively drug-resistant Mycobacterium tuberculosis strains in multidrug-resistant tuberculosis patients undergoing treatment. Feuerriegel S, Cox HS, Zarkua N, Karimovich HA, Braker K, Rüsch-Gerdes S, Niemann S, Antimicrob Agents Chemother 2009 53 8 3353 3356 10.1128/AAC.00050-09 19470506
27. Evaluation of the MTBDRsl test for detection of second-line-drug resistance in Mycobacterium tuberculosis. Kiet VS, Lan NTN, An DD, Dung NH, Hoa DV, Chau NV, Chinh NT, Farrar J, Caws M, J Clin Microbiol 2010 48 8 2934 2939 10.1128/JCM.00201-10 20573868
28. Mutations in the rrs A1401G gene and phenotypic resistance to amikacin and capreomycin in Mycobacterium tuberculosis. Sirgel FA, Tait M, Warren RM, Streicher EM, Böttger EC, Van Helden PD, Gey Van Pittius NC, Coetzee G, Hoosain EY, Chabula-Nxiweni M, Hayes C, Victor TC, Trollip A, Microb Drug Resist 2012 2012 18 2 193 197
29. Detection of kanamycin-resistant Mycobacterium tuberculosis by identifying mutations in the 16S rRNA gene. Suzuki Y, Katsukawa C, Tamaru A, Abe C, Makino M, Mizuguchi Y, Taniguchi H, J Clin Microbiol 1998 36 5 1220 1225 9574680 (Pubitemid 28208002)
30. Evaluation of genetic mutations associated with Mycobacterium tuberculosis resistance to amikacin, kanamycin and capreomycin: a systematic review. Georghiou SB, Magana M, Garfein RS, Catanzaro DG, Catanzaro A, Rodwell TC, PLoS One 2012 7 3 33275 10.1371/journal.pone.0033275 22479378
31. High level of cross-resistance between kanamycin, amikacin and capreomycin among Mycobacterium tuberculosis isolates from Georgia and a close relation with mutations in the rrs gene. Jugheli L, Bzekalava N, Rijk PD, Fissette K, Portaels F, Rigouts L, Antimicrob Agents Chemother 2009 53 12 5064 5068 10.1128/AAC.00851-09 19752274
32. Discordant resistance to kanamycin and amikacin in drug-resistant Mycobacterium tuberculosis. Krüüner A, Jureen P, Levina K, Ghebremichael S, Hoffner S, Antimicrob Agents Chemother 2003 47 9 2971 2973 10.1128/AAC.47.9.2971-2973.2003 12937004 (Pubitemid 37040278)
33. Unusual regioversatility of acetyltransferase Eis, a cause of drug resistance in XDR-TB. Chen W, Biswas T, Porter VR, Tsodikov OV, Garneau-Tsodikova S, Proc Natl Acad Sci U S A 2011 108 24 9804 9808 10.1073/pnas.1105379108 21628583
34. The multidrug transporters belonging to major facilitator superfamily (MFS) in Mycobacterium tuberculosis. De Rossi E, Arrigo P, Bellinzoni M, Silva PEA, Martin C, Aínsa JA, Guglierame P, Riccardi G, Mol Med 2002 8 11 714 724 12520088 (Pubitemid 36337498)
35. Mycobacterium tuberculosis isolate with a distinct genomic identity overexpresses a Tap-like efflux pump. Siddiqi N, Das R, Pathak N, Banerjee S, Ahmed N, Katoch VM, Hasnain SE, Infection 2004 32 2 109 111 10.1007/s15010-004- 3097-x 15057575 (Pubitemid 38457104)
36. Consequences of whiB7 (Rv3197A) mutations in Beijing genotype isolates of the Mycobacterium tuberculosis complex. Köser CU, Bryant JM, Parkhill J, Peacock SJ, Antimicrob Agents Chemother 2013 57 7 3461 10.1128/AAC.00626-13 23761426
37. Analysis of mutations in streptomycin-resistant strains reveals a simple and reliable genetic marker for identification of the Mycobacterium tuberculosis Beijing genotype. Villellas C, Aristimuño L, Vitoria M-A, Prat C, Blanco S, de Viedma DG, Domínguez J, Samper S, Aínsa JA, J Clin Microbiol 2013 51 7 2124 2130 10.1128/JCM.01944-12 23616454
38. Molecular genetics of Mycobacterium tuberculosis resistant to aminoglycosides and cyclic peptide capreomycin antibiotics in Korea. Jnawali HN, Yoo H, Ryoo S, Lee KJ, Kim BJ, Koh WJ, Kim CK, Kim HJ, Park YK, World J Microbiol Biotechnol 2013 29 6 975 982 10.1007/s11274-013-1256-x 23329063
39. One-tube multiplex PCR method for rapid identification of Mycobacterium tuberculosis. Chaiprasert A, Prammananan T, Tingtoy N, Na-Ubol P, Srimuang S, Samerpitak K, Rangsipanuratn W, Southeast Asian J Trop Med Publ Health 2006 37 3 494 502
40. Quality assurance programme for drug susceptibility testing of Mycobacterium tuberculosis in the WHO/IUATLD supranational reference laboratory network: Five rounds of proficiency testing, 1994-1998. Laszlo A, Rahman M, Espinal M, Raviglione M, Int J Tuberc Lung Dis 2002 6 9 748 756 12234129 (Pubitemid 34988044)
41. Susceptibility testing of Mycobacteria, Nocardiae, and other aerobic Actinomycetes; Approved standard. National Committee for Clinical Laboratory Standards, Wayne, PA: Document M24-A, National Committee for Clinical Laboratory Standards 2003
42. Next-generation ion torrent sequencing of drug resistance mutations in Mycobacterium tuberculosis strains. Daum LT, Rodriguez JD, Worthy SA, Ismail NA, Omar SV, Dreyer AW, Fourie PB, Hoosen AA, Chambers JP, Fischer GW, J Clin Microbiol 2012 50 12 3831 3837 10.1128/JCM.01893-12 22972833
43. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Thompson JD, Higgins DG, Gibson TJ, Nucl Acids Res 1994 22 22 4673 4680 10.1093/nar/22.22.4673 7984417 (Pubitemid 24354800)