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Volumn 63, Issue 29, 2015, Pages 6535-6545

Sulfated and Glucuronated trans-Resveratrol Metabolites Regulate Chemokines and Sirtuin-1 Expression in U-937 Macrophages

Author keywords

chemokines; immune cells; macrophages; MCP 1; receptors; resveratrol metabolites

Indexed keywords

BIOCHEMISTRY; CELLS; CYTOLOGY; MACROPHAGES; METABOLITES; PEPTIDES; PHYSIOLOGICAL MODELS; PROTEINS; RESVERATROL;

EID: 84938295580     PISSN: 00218561     EISSN: 15205118     Source Type: Journal    
DOI: 10.1021/acs.jafc.5b01830     Document Type: Article
Times cited : (25)

References (50)
  • 1
    • 20344407841 scopus 로고    scopus 로고
    • Resveratrol as an anti-inflammatory and anti-aging agent: Mechanisms and clinical implications
    • Alarcón, C.; Villegas, I. Resveratrol as an anti-inflammatory and anti-aging agent: Mechanisms and clinical implications Mol. Nutr. Food Res. 2005, 49, 405-430
    • (2005) Mol. Nutr. Food Res. , vol.49 , pp. 405-430
    • Alarcón, C.1    Villegas, I.2
  • 2
    • 0033952265 scopus 로고    scopus 로고
    • Effect of resveratrol, a natural polyphenolic compound, on reactive oxygen species and prostaglandin production
    • Martinez, J.; Moreno, J. Effect of resveratrol, a natural polyphenolic compound, on reactive oxygen species and prostaglandin production Biochem. Pharmacol. 2000, 59, 865-870 10.1016/S0006-2952(99)00380-9
    • (2000) Biochem. Pharmacol. , vol.59 , pp. 865-870
    • Martinez, J.1    Moreno, J.2
  • 3
    • 0033917861 scopus 로고    scopus 로고
    • Resveratrol modulates arachidonic acid release, prostaglandin synthesis, and 3t6 fibroblast growth
    • Moreno, J. Resveratrol modulates arachidonic acid release, prostaglandin synthesis, and 3t6 fibroblast growth J. Pharmacol. Exp. Ther. 2000, 294, 333-338
    • (2000) J. Pharmacol. Exp. Ther. , vol.294 , pp. 333-338
    • Moreno, J.1
  • 4
    • 84868308799 scopus 로고    scopus 로고
    • Resveratrol, microRNAs, inflammation, and cancer
    • Tili, E.; Michaille, J. J. Resveratrol, microRNAs, inflammation, and cancer J. Nucleic Acids 2011, 2011, 1-9 10.4061/2011/102431
    • (2011) J. Nucleic Acids , vol.2011 , pp. 1-9
    • Tili, E.1    Michaille, J.J.2
  • 5
    • 9444296057 scopus 로고    scopus 로고
    • High absorption but very low bioavailability of oral resveratrol in humans
    • Walle, T.; Hsieh, F.; DeLegge, M. H.; Oatis, J. E.; Walle, U. K. High absorption but very low bioavailability of oral resveratrol in humans Drug Metab. Dispos. 2004, 32, 1377 10.1124/dmd.104.000885
    • (2004) Drug Metab. Dispos. , vol.32 , pp. 1377
    • Walle, T.1    Hsieh, F.2    Delegge, M.H.3    Oatis, J.E.4    Walle, U.K.5
  • 6
    • 20344364428 scopus 로고    scopus 로고
    • Metabolism and bioavailability of trans-resveratrol
    • Wenzel, E.; Somoza, V. Metabolism and bioavailability of trans-resveratrol Mol. Nutr. Food Res. 2005, 49, 472-481 10.1002/mnfr.200500010
    • (2005) Mol. Nutr. Food Res. , vol.49 , pp. 472-481
    • Wenzel, E.1    Somoza, V.2
  • 9
    • 48649106985 scopus 로고    scopus 로고
    • Quantification of free and proteine-bound trans-resveratrol metabolites and identification of trans-resveratrol-c/o-conjugated diglucuronides-two novel resveratrol metabolites in human plasma
    • Burkon, A.; Somoza, V. Quantification of free and proteine-bound trans-resveratrol metabolites and identification of trans-resveratrol-c/o-conjugated diglucuronides-two novel resveratrol metabolites in human plasma Mol. Nutr. Food Res. 2008, 52, 549-557 10.1002/mnfr.200700290
    • (2008) Mol. Nutr. Food Res. , vol.52 , pp. 549-557
    • Burkon, A.1    Somoza, V.2
  • 10
    • 84861102186 scopus 로고    scopus 로고
    • Resveratrol metabolites have an antiproliferative effect on intestinal epithelial cancer cells
    • Storniolo, C. E.; Moreno, J. J. Resveratrol metabolites have an antiproliferative effect on intestinal epithelial cancer cells Food Chem. 2012, 134, 1385-1391 10.1016/j.foodchem.2012.03.036
    • (2012) Food Chem. , vol.134 , pp. 1385-1391
    • Storniolo, C.E.1    Moreno, J.J.2
  • 11
    • 84880380605 scopus 로고    scopus 로고
    • Resveratrol and its metabolites modulate cytokine-mediated induction of eotaxin-1 in human pulmonary artery endothelial cells
    • Wu, J. M.; Hsieh, T.-c.; Yang, C.-J.; Olson, S. C. Resveratrol and its metabolites modulate cytokine-mediated induction of eotaxin-1 in human pulmonary artery endothelial cells Ann. N. Y. Acad. Sci. 2013, 1290, 30-36 10.1111/nyas.12151
    • (2013) Ann. N. Y. Acad. Sci. , vol.1290 , pp. 30-36
    • Wu, J.M.1    Hsieh, T.-C.2    Yang, C.-J.3    Olson, S.C.4
  • 12
    • 84890905758 scopus 로고    scopus 로고
    • Resveratrol and its metabolites inhibit pro-inflammatory effects of lipopolysaccharides in U-937 macrophages in plasma-representative concentrations
    • Walker, J.; Schueller, K.; Schaefer, L.-M.; Pignitter, M.; Esefelder, L.; Somoza, V. Resveratrol and its metabolites inhibit pro-inflammatory effects of lipopolysaccharides in U-937 macrophages in plasma-representative concentrations Food Funct. 2013, 5, 74-84 10.1039/C3FO60236B
    • (2013) Food Funct. , vol.5 , pp. 74-84
    • Walker, J.1    Schueller, K.2    Schaefer, L.-M.3    Pignitter, M.4    Esefelder, L.5    Somoza, V.6
  • 13
    • 84866012639 scopus 로고    scopus 로고
    • Modulation of NF-kappa b activation by resveratrol in LPS treated human intestinal cells results in downregulation of PGE(2) production and COX-2 expression
    • Cianciulli, A.; Calvello, R.; Cavallo, P.; Dragone, T.; Carofiglio, V.; Panaro, M. A. Modulation of NF-kappa b activation by resveratrol in LPS treated human intestinal cells results in downregulation of PGE(2) production and COX-2 expression Toxicol. In Vitro 2012, 26, 1122-1128 10.1016/j.tiv.2012.06.015
    • (2012) Toxicol. In Vitro , vol.26 , pp. 1122-1128
    • Cianciulli, A.1    Calvello, R.2    Cavallo, P.3    Dragone, T.4    Carofiglio, V.5    Panaro, M.A.6
  • 15
    • 84866149276 scopus 로고    scopus 로고
    • The chemokine receptors CXCR1 and CXCR2 couple to distinct G protein-coupled receptor kinases to mediate and regulate leukocyte functions
    • Raghuwanshi, S. K.; Su, Y.; Singh, V.; Haynes, K.; Richmond, A.; Richardson, R. M. The chemokine receptors CXCR1 and CXCR2 couple to distinct G protein-coupled receptor kinases to mediate and regulate leukocyte functions J. Immunol. 2012, 189, 2824-32 10.4049/jimmunol.1201114
    • (2012) J. Immunol. , vol.189 , pp. 2824-2832
    • Raghuwanshi, S.K.1    Su, Y.2    Singh, V.3    Haynes, K.4    Richmond, A.5    Richardson, R.M.6
  • 16
    • 34249083199 scopus 로고    scopus 로고
    • Sirtuins in mammals: Insights into their biological function
    • Michan, S.; Sinclair, D. Sirtuins in mammals: Insights into their biological function Biochem. J. 2007, 404, 1-13 10.1042/BJ20070140
    • (2007) Biochem. J. , vol.404 , pp. 1-13
    • Michan, S.1    Sinclair, D.2
  • 17
    • 79953196857 scopus 로고    scopus 로고
    • Epigallocatechin-3-gallate reduces airway inflammation in mice through binding to proinflammatory chemokines and inhibiting inflammatory cell recruitment
    • Qin, S.; Alcorn, J. F.; Craigo, J. K.; Tjoeng, C.; Tarwater, P. M.; Kolls, J. K.; Reinhart, T. A. Epigallocatechin-3-gallate reduces airway inflammation in mice through binding to proinflammatory chemokines and inhibiting inflammatory cell recruitment J. Immunol. 2011, 186, 3693-3700 10.4049/jimmunol.1002876
    • (2011) J. Immunol. , vol.186 , pp. 3693-3700
    • Qin, S.1    Alcorn, J.F.2    Craigo, J.K.3    Tjoeng, C.4    Tarwater, P.M.5    Kolls, J.K.6    Reinhart, T.A.7
  • 18
    • 79952234852 scopus 로고    scopus 로고
    • Inhibition of TNF-alpha mediated endothelial cell-monocyte cell adhesion and adhesion molecules expression by the resveratrol derivative, trans-3,5,4′-trimethoxystilbene
    • Deng, Y.-H.; Alex, D.; Huang, H.-Q.; Wang, N.; Yu, N.; Wang, Y.-T.; Leung, G. P. H.; Lee, S. M.-Y. Inhibition of TNF-alpha mediated endothelial cell-monocyte cell adhesion and adhesion molecules expression by the resveratrol derivative, trans-3,5,4′-trimethoxystilbene Phytother. Res. 2011, 25, 451-457 10.1002/ptr.3279
    • (2011) Phytother. Res. , vol.25 , pp. 451-457
    • Deng, Y.-H.1    Alex, D.2    Huang, H.-Q.3    Wang, N.4    Yu, N.5    Wang, Y.-T.6    Leung, G.P.H.7    Lee, S.M.-Y.8
  • 19
    • 34948858345 scopus 로고    scopus 로고
    • Resveratrol inhibits expression and binding activity of the monocyte chemotactic protein-1 receptor, CCR2, on THP-1 monocytes
    • Cullen, J. P.; Morrow, D.; Jin, Y.; von Offenberg Sweeney, N.; Sitzmann, J. V.; Cahill, P. A.; Redmond, E. M. Resveratrol inhibits expression and binding activity of the monocyte chemotactic protein-1 receptor, CCR2, on THP-1 monocytes Atherosclerosis 2007, 195, e125-e133 10.1016/j.atherosclerosis.2007.03.039
    • (2007) Atherosclerosis , vol.195 , pp. e125-e133
    • Cullen, J.P.1    Morrow, D.2    Jin, Y.3    Von Offenberg Sweeney, N.4    Sitzmann, J.V.5    Cahill, P.A.6    Redmond, E.M.7
  • 21
    • 77249089947 scopus 로고    scopus 로고
    • Resveratrol (trans-3,5,4′-trihydroxystilbene) induces silent mating type information regulation-1 and down-regulates nuclear transcription factor-kB activation to abrogate dextran sulfate sodium-induced colitis
    • Singh, U. P.; Singh, N. P.; Singh, B.; Hofseth, L. J.; Price, R. L.; Nagarkatti, M.; Nagarkatti, P. S. Resveratrol (trans-3,5,4′-trihydroxystilbene) induces silent mating type information regulation-1 and down-regulates nuclear transcription factor-kB activation to abrogate dextran sulfate sodium-induced colitis J. Pharmacol. Exp. Ther. 2010, 332, 829-839 10.1124/jpet.109.160838
    • (2010) J. Pharmacol. Exp. Ther. , vol.332 , pp. 829-839
    • Singh, U.P.1    Singh, N.P.2    Singh, B.3    Hofseth, L.J.4    Price, R.L.5    Nagarkatti, M.6    Nagarkatti, P.S.7
  • 22
    • 77953616099 scopus 로고    scopus 로고
    • Periodontitis: A polymicrobial disruption of host homeostasis
    • Darveau, R. P. Periodontitis: A polymicrobial disruption of host homeostasis Nat. Rev. Microbiol. 2010, 8, 481-90 10.1038/nrmicro2337
    • (2010) Nat. Rev. Microbiol. , vol.8 , pp. 481-490
    • Darveau, R.P.1
  • 23
    • 0034636021 scopus 로고    scopus 로고
    • Glucocorticoids repress nf-kb-driven genes by disturbing the interaction of p65 with the basal transcription machinery, irrespective of coactivator levels in the cell
    • De Bosscher, K.; Berghe, W. V.; Vermeulen, L.; Plaisance, S.; Boone, E.; Haegeman, G. Glucocorticoids repress nf-kb-driven genes by disturbing the interaction of p65 with the basal transcription machinery, irrespective of coactivator levels in the cell Proc. Natl. Acad. Sci. U. S. A. 2000, 97, 3919-3924 10.1073/pnas.97.8.3919
    • (2000) Proc. Natl. Acad. Sci. U. S. A. , vol.97 , pp. 3919-3924
    • De Bosscher, K.1    Berghe, W.V.2    Vermeulen, L.3    Plaisance, S.4    Boone, E.5    Haegeman, G.6
  • 24
    • 0037021584 scopus 로고    scopus 로고
    • Capillary electrophoresis determination, synthesis, and stability of resveratrol and related 3-O-β-D-glucopyranosides
    • Brandolini, V.; Maietti, A.; Tedeschi, P.; Durini, E.; Vertuani, S.; Manfredini, S. Capillary electrophoresis determination, synthesis, and stability of resveratrol and related 3-O-β-D-glucopyranosides J. Agric. Food Chem. 2002, 50, 7407 10.1021/jf0256384
    • (2002) J. Agric. Food Chem. , vol.50 , pp. 7407
    • Brandolini, V.1    Maietti, A.2    Tedeschi, P.3    Durini, E.4    Vertuani, S.5    Manfredini, S.6
  • 25
    • 20344371723 scopus 로고    scopus 로고
    • Bioactivity and metabolism of trans-resveratrol orally administered to wistar rats
    • Wenzel, E.; Soldo, T.; Erbersdobler, H.; Somoza, V. Bioactivity and metabolism of trans-resveratrol orally administered to wistar rats Mol. Nutr. Food Res. 2005, 49, 482-494 10.1002/mnfr.200500003
    • (2005) Mol. Nutr. Food Res. , vol.49 , pp. 482-494
    • Wenzel, E.1    Soldo, T.2    Erbersdobler, H.3    Somoza, V.4
  • 27
    • 84911863742 scopus 로고    scopus 로고
    • Impact of trans-resveratrol-sulfates and -glucuronides on endothelial nitric oxide synthase activity, nitric oxide release and intracellular reactive oxygen species
    • Ladurner, A.; Schachner, D.; Schueller, K.; Pignitter, M.; Heiss, E. H.; Somoza, V.; Dirsch, V. M. Impact of trans-resveratrol-sulfates and -glucuronides on endothelial nitric oxide synthase activity, nitric oxide release and intracellular reactive oxygen species Molecules 2014, 19, 16724-36 10.3390/molecules191016724
    • (2014) Molecules , vol.19 , pp. 16724-16736
    • Ladurner, A.1    Schachner, D.2    Schueller, K.3    Pignitter, M.4    Heiss, E.H.5    Somoza, V.6    Dirsch, V.M.7
  • 28
  • 30
    • 84858616945 scopus 로고    scopus 로고
    • Modulation of the expression of ABC transporters in murine (j774) macrophages exposed to large concentrations of the fluoroquinolone antibiotic moxifloxacin
    • Vallet, C. M.; Marquez, B.; Nhiri, N.; Anantharajah, A.; Mingeot-Leclercq, M.-P.; Tulkens, P. M.; Lallemand, J.-Y.; Jacquet, E.; Van Bambeke, F. Modulation of the expression of ABC transporters in murine (j774) macrophages exposed to large concentrations of the fluoroquinolone antibiotic moxifloxacin Toxicology 2011, 290, 178-186 10.1016/j.tox.2011.09.003
    • (2011) Toxicology , vol.290 , pp. 178-186
    • Vallet, C.M.1    Marquez, B.2    Nhiri, N.3    Anantharajah, A.4    Mingeot-Leclercq, M.-P.5    Tulkens, P.M.6    Lallemand, J.-Y.7    Jacquet, E.8    Van Bambeke, F.9
  • 31
    • 63849152475 scopus 로고    scopus 로고
    • Intestinal breast cancer resistance protein (BCRP)/BCRP1 and multidrug resistance protein 3 (MRP3)/MRP3 are involved in the pharmacokinetics of resveratrol
    • van de Wetering, K.; Burkon, A.; Feddema, W.; Bot, A.; de Jonge, H.; Somoza, V.; Borst, P. Intestinal breast cancer resistance protein (BCRP)/BCRP1 and multidrug resistance protein 3 (MRP3)/MRP3 are involved in the pharmacokinetics of resveratrol Mol. Pharmacol. 2009, 75, 876-885 10.1124/mol.108.052019
    • (2009) Mol. Pharmacol. , vol.75 , pp. 876-885
    • Van De Wetering, K.1    Burkon, A.2    Feddema, W.3    Bot, A.4    De Jonge, H.5    Somoza, V.6    Borst, P.7
  • 32
    • 0031444281 scopus 로고    scopus 로고
    • Resveratrol, a polyphenolic compound found in grapes and wine, is an agonist for the estrogen receptor
    • Gehm, B. D.; McAndrews, J. M.; Chien, P. Y.; Jameson, J. L. Resveratrol, a polyphenolic compound found in grapes and wine, is an agonist for the estrogen receptor Proc. Natl. Acad. Sci. U. S. A. 1997, 94, 14138-14143 10.1073/pnas.94.25.14138
    • (1997) Proc. Natl. Acad. Sci. U. S. A. , vol.94 , pp. 14138-14143
    • Gehm, B.D.1    McAndrews, J.M.2    Chien, P.Y.3    Jameson, J.L.4
  • 33
    • 77952497806 scopus 로고    scopus 로고
    • Suppression of the inflammatory response in experimental arthritis is mediated via estrogen receptor alpha but not estrogen receptor beta
    • Dulos, J.; Vijn, P.; van Doorn, C.; Hofstra, C. L.; Veening-Griffioen, D.; de Graaf, J.; Dijcks, F. A.; Boots, A. M. H. Suppression of the inflammatory response in experimental arthritis is mediated via estrogen receptor alpha but not estrogen receptor beta Arthritis Res. Ther. 2009, 12, R101-R101 10.1186/ar3032
    • (2009) Arthritis Res. Ther. , vol.12 , pp. R101-R101
    • Dulos, J.1    Vijn, P.2    Van Doorn, C.3    Hofstra, C.L.4    Veening-Griffioen, D.5    De Graaf, J.6    Dijcks, F.A.7    Boots, A.M.H.8
  • 34
    • 77950546179 scopus 로고    scopus 로고
    • Green tea extract inhibits chemokine production, but up-regulates chemokine receptor expression, in rheumatoid arthritis synovial fibroblasts and rat adjuvant-induced arthritis
    • Marotte, H.; Ruth, J. H.; Campbell, P. L.; Koch, A. E.; Ahmed, S. Green tea extract inhibits chemokine production, but up-regulates chemokine receptor expression, in rheumatoid arthritis synovial fibroblasts and rat adjuvant-induced arthritis Rheumatology 2010, 49, 467-479 10.1093/rheumatology/kep397
    • (2010) Rheumatology , vol.49 , pp. 467-479
    • Marotte, H.1    Ruth, J.H.2    Campbell, P.L.3    Koch, A.E.4    Ahmed, S.5
  • 36
    • 84884368396 scopus 로고    scopus 로고
    • Protective effect of SIRT1 on toxicity of microglial-derived factors induced by LPS to PC12 cells via the p53-caspase-3-dependent apoptotic pathway
    • Ye, J.; Liu, Z.; Wei, J.; Lu, L.; Huang, Y.; Luo, L.; Xie, H. Protective effect of SIRT1 on toxicity of microglial-derived factors induced by LPS to PC12 cells via the p53-caspase-3-dependent apoptotic pathway Neurosci. Lett. 2013, 553, 72-77 10.1016/j.neulet.2013.08.020
    • (2013) Neurosci. Lett. , vol.553 , pp. 72-77
    • Ye, J.1    Liu, Z.2    Wei, J.3    Lu, L.4    Huang, Y.5    Luo, L.6    Xie, H.7
  • 38
    • 77649267205 scopus 로고    scopus 로고
    • The identification of markers of macrophage differentiation in PMA-stimulated THP-1 cells and monocyte-derived macrophages (macrophage differentiation)
    • Daigneault, M.; Preston, J. A.; Marriott, H. M.; Whyte, M. K. B.; Dockrell, D. H. The identification of markers of macrophage differentiation in PMA-stimulated THP-1 cells and monocyte-derived macrophages (macrophage differentiation) PLoS One 2010, 5, e8668 10.1371/journal.pone.0008668
    • (2010) PLoS One , vol.5 , pp. 8668
    • Daigneault, M.1    Preston, J.A.2    Marriott, H.M.3    Whyte, M.K.B.4    Dockrell, D.H.5
  • 40
  • 41
    • 84872325865 scopus 로고    scopus 로고
    • Control of eotaxin-1 expression and release by resveratrol and its metabolites in culture human pulmonary artery endothelial cells
    • Yang, C. J.; Lin, C. Y.; Hsieh, T. C.; Olson, S. C.; Wu, J. M. Control of eotaxin-1 expression and release by resveratrol and its metabolites in culture human pulmonary artery endothelial cells Am. J. Cardiovasc. Dis. 2011, 1, 16-30
    • (2011) Am. J. Cardiovasc. Dis. , vol.1 , pp. 16-30
    • Yang, C.J.1    Lin, C.Y.2    Hsieh, T.C.3    Olson, S.C.4    Wu, J.M.5
  • 42
    • 33646177532 scopus 로고    scopus 로고
    • Scoparone inhibits PMA-induced IL-8 and MCP-1 production through suppression of NF-κB activation in U937 cells
    • Jang, S. I.; Kim, Y.-J.; Kim, H. J.; Lee, J.-C.; Kim, H.-Y.; Kim, Y.-C.; Yun, Y.-g.; Yu, H.-H.; You, Y.-O. Scoparone inhibits PMA-induced IL-8 and MCP-1 production through suppression of NF-κB activation in U937 cells Life Sci. 2006, 78, 2937-2943 10.1016/j.lfs.2005.11.020
    • (2006) Life Sci. , vol.78 , pp. 2937-2943
    • Jang, S.I.1    Kim, Y.-J.2    Kim, H.J.3    Lee, J.-C.4    Kim, H.-Y.5    Kim, Y.-C.6    Yun, Y.-G.7    Yu, H.-H.8    You, Y.-O.9
  • 43
    • 84879799217 scopus 로고    scopus 로고
    • Resveratrol metabolites inhibit human metastatic colon cancer cells progression and synergize with chemotherapeutic drugs to induce cell death
    • Aires, V.; Limagne, E.; Cotte, A. K.; Latruffe, N.; Ghiringhelli, F.; Delmas, D. Resveratrol metabolites inhibit human metastatic colon cancer cells progression and synergize with chemotherapeutic drugs to induce cell death Mol. Nutr. Food Res. 2013, 57, 1170-1181 10.1002/mnfr.201200766
    • (2013) Mol. Nutr. Food Res. , vol.57 , pp. 1170-1181
    • Aires, V.1    Limagne, E.2    Cotte, A.K.3    Latruffe, N.4    Ghiringhelli, F.5    Delmas, D.6
  • 44
    • 84897567794 scopus 로고    scopus 로고
    • Quercetin, but not its metabolite quercetin-3-glucuronide, exerts prophylactic immunostimulatory activity and therapeutic antiinflammatory effects on lipopolysaccharide-treated mouse peritoneal macrophages ex vivo
    • Liao, Y.; Lin, J. Quercetin, but not its metabolite quercetin-3-glucuronide, exerts prophylactic immunostimulatory activity and therapeutic antiinflammatory effects on lipopolysaccharide-treated mouse peritoneal macrophages ex vivo J. Agric. Food Chem. 2014, 62, 2872-2880 10.1021/jf405630h
    • (2014) J. Agric. Food Chem. , vol.62 , pp. 2872-2880
    • Liao, Y.1    Lin, J.2
  • 47
    • 0032508720 scopus 로고    scopus 로고
    • Differential cross-regulation of the human chemokine receptors CXCR1 and CXCR2. Evidence for time-dependent signal generation
    • Richardson, R. M.; Pridgen, B. C.; Haribabu, B.; Ali, H.; Snyderman, R. Differential cross-regulation of the human chemokine receptors CXCR1 and CXCR2. Evidence for time-dependent signal generation J. Biol. Chem. 1998, 273, 23826-23830 10.1074/jbc.273.37.23830
    • (1998) J. Biol. Chem. , vol.273 , pp. 23826-23830
    • Richardson, R.M.1    Pridgen, B.C.2    Haribabu, B.3    Ali, H.4    Snyderman, R.5
  • 48
    • 84938381154 scopus 로고    scopus 로고
    • Cocaine down regulates microRNA-146a with a reciprocal up-regulation of CXCR-4: Implications in HIV immunopathogenesis
    • Pilakka-Kanthikeel, S.; Napuri, J.; Nair, M. P. N. Cocaine down regulates microRNA-146a with a reciprocal up-regulation of CXCR-4: Implications in HIV immunopathogenesis J. Neuroimmune Pharm. 2012, 7, S49
    • (2012) J. Neuroimmune Pharm. , vol.7 , pp. S49
    • Pilakka-Kanthikeel, S.1    Napuri, J.2    Nair, M.P.N.3
  • 49
    • 79961090786 scopus 로고    scopus 로고
    • High dose of dietary resveratrol enhances insulin sensitivity in healthy rats but does not lead to metabolite concentrations effective for SIRT1 expression
    • Andersen, G.; Burkon, A.; Sulzmaier, F. J.; Walker, J. M.; Leckband, G.; Fuhst, R.; Erbersdobler, H. F.; Somoza, V. High dose of dietary resveratrol enhances insulin sensitivity in healthy rats but does not lead to metabolite concentrations effective for SIRT1 expression Mol. Nutr. Food Res. 2011, 55, 1197-1206 10.1002/mnfr.201100292
    • (2011) Mol. Nutr. Food Res. , vol.55 , pp. 1197-1206
    • Andersen, G.1    Burkon, A.2    Sulzmaier, F.J.3    Walker, J.M.4    Leckband, G.5    Fuhst, R.6    Erbersdobler, H.F.7    Somoza, V.8


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