Altered lysosomal positioning affects lysosomal functions in a cellular model of Huntington's disease

European Journal of Neuroscience

Volumn 42, Issue 3, 2015, Pages 1941-1951

  Erie, Christine ^a   Sacino, Matthew ^a   Houle, Lauren ^a   Lu, Michael L ^a   Wei, Jianning ^a  

^a FLORIDA ATLANTIC UNIVERSITY   (United States)

Author keywords

Autophagic influx; Autophagy; Lamp1; mTORC1; Vesicular trafficking

Indexed keywords

HUNTINGTIN; MAMMALIAN TARGET OF RAPAMYCIN COMPLEX 1; HTT PROTEIN, HUMAN; MECHANISTIC TARGET OF RAPAMYCIN COMPLEX 1; MULTIPROTEIN COMPLEX; NERVE PROTEIN; TARGET OF RAPAMYCIN KINASE;

ADULT; ANIMAL CELL; ARTICLE; AUTOPHAGOSOME; AUTOPHAGY; CELL FUNCTION; CELL FUSION; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENZYME ACTIVITY; FIBROBLAST; HUMAN; HUMAN CELL; HUNTINGTON CHOREA; LYSOSOME; LYSOSOME FUNCTION; LYSOSOME POSITION; MOUSE; NEUROPATHOLOGY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; CELL CULTURE; CORPUS STRIATUM; CYTOLOGY; DISEASE MODEL; GENE TARGETING; GENETICS; METABOLISM; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; AUTOPHAGY; BIOLOGICAL TRANSPORT; CELLS, CULTURED; CORPUS STRIATUM; DISEASE MODELS, ANIMAL; FIBROBLASTS; GENE KNOCK-IN TECHNIQUES; HUNTINGTIN PROTEIN; HUNTINGTON DISEASE; LYSOSOMES; MICE; MULTIPROTEIN COMPLEXES; NERVE TISSUE PROTEINS; TOR SERINE-THREONINE KINASES;

EID: 84938287341     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/ejn.12957     Document Type: Article

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