How osmolytes influence hydrophobic polymer conformations: A unified view from experiment and theory

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 30, 2015, Pages 9270-9275

  Mondal, Jagannath ^a,b   Halverson, Duncan ^c   Li, Isaac T S ^c   Stirnemann, Guillaume ^d   Walker, Gilbert C ^c   Berne, Bruce J ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b TATA INSTITUTE OF FUNDAMENTAL RESEARCH   (India)

^c UNIVERSITY OF TORONTO   (Canada)

^d PSL RESEARCH UNIVERSITY   (France)

Author keywords

Free energy; Preferential binding; Single molecule force spectroscopy; TMAO; Urea

Indexed keywords

POLYSTYRENE; TRIMETHYLAMINE OXIDE; UREA; METHYLAMINE; POLYMER; POLYSTYRENE DERIVATIVE; PROTEIN; PROTEIN BINDING; SOLVENT; TRIMETHYLOXAMINE; WATER;

AQUEOUS SOLUTION; ARTICLE; ATOMIC FORCE MICROSCOPY; BINDING AFFINITY; CHEMICAL INTERACTION; COMPUTER SIMULATION; CONFORMATION; CONTACT ANGLE; EQUILIBRIUM CONSTANT; MOLECULAR DYNAMICS; POLYMERIZATION; PRIORITY JOURNAL; SURFACE TENSION; CHEMICAL PHENOMENA; CHEMISTRY; COMPUTER PROGRAM; MECHANICAL STRESS; NORMAL DISTRIBUTION; PROTEIN CONFORMATION; PROTEIN FOLDING; THERMODYNAMICS;

COMPUTER SIMULATION; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; METHYLAMINES; MICROSCOPY, ATOMIC FORCE; MOLECULAR DYNAMICS SIMULATION; NORMAL DISTRIBUTION; POLYMERS; POLYSTYRENES; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEINS; SOFTWARE; SOLVENTS; STRESS, MECHANICAL; THERMODYNAMICS; UREA; WATER;

EID: 84938118055     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1511780112     Document Type: Article

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