메뉴 건너뛰기




Volumn 72, Issue 11, 2015, Pages 2237-2248

Circadian clocks in rat skin and dermal fibroblasts: Differential effects of aging, temperature and melatonin

Author keywords

Age; Bioluminescence; Circadian rhythms; Development; Per1

Indexed keywords

CIRCADIAN RHYTHM SIGNALING PROTEIN; MELATONIN; PER1 PROTEIN, RAT; PER2 PROTEIN, RAT;

EID: 84938090416     PISSN: 1420682X     EISSN: 14209071     Source Type: Journal    
DOI: 10.1007/s00018-014-1809-7     Document Type: Article
Times cited : (35)

References (64)
  • 1
    • 33749031807 scopus 로고    scopus 로고
    • Molecular components of the mammalian circadian clock
    • Ko CH, Takahashi JS (2006) Molecular components of the mammalian circadian clock. Hum Mol Genet 15 Spec No 2:271-277
    • (2006) Hum Mol Genet , vol.152 , pp. 271-277
    • Ko, C.H.1    Takahashi, J.S.2
  • 4
    • 84891546261 scopus 로고    scopus 로고
    • Organ-specific development characterizes circadian clock gene Per2 expression in rats
    • 1:CAS:528:DC%2BC2cXitleisL0%3D 24133102
    • Nishide SY, Hashimoto K, Nishio T, Honma K, Honma S (2014) Organ-specific development characterizes circadian clock gene Per2 expression in rats. Am J Physiol Regul Integr Comp Physiol 306(1):R67-R74
    • (2014) Am J Physiol Regul Integr Comp Physiol , vol.306 , Issue.1 , pp. 67-R74
    • Nishide, S.Y.1    Hashimoto, K.2    Nishio, T.3    Honma, K.4    Honma, S.5
  • 5
    • 0036460459 scopus 로고    scopus 로고
    • Effects of nursing mothers on rPer1 and rPer2 circadian expressions in the neonatal rat suprachiasmatic nuclei vary with developmental stage
    • 12099901
    • Ohta H, Honma S, Abe H, Honma K (2002) Effects of nursing mothers on rPer1 and rPer2 circadian expressions in the neonatal rat suprachiasmatic nuclei vary with developmental stage. Eur J Neurosci 15(12):1953-1960
    • (2002) Eur J Neurosci , vol.15 , Issue.12 , pp. 1953-1960
    • Ohta, H.1    Honma, S.2    Abe, H.3    Honma, K.4
  • 6
    • 0021204083 scopus 로고
    • The suprachiasmatic nuclei of the fetal rat: Characterization of a functional circadian clock using 14C-labeled deoxyglucose
    • 1:STN:280:DyaL2c3ktF2nsA%3D%3D 6737036
    • Reppert SM, Schwartz WJ (1984) The suprachiasmatic nuclei of the fetal rat: characterization of a functional circadian clock using 14C-labeled deoxyglucose. J Neurosci 4(7):1677-1682
    • (1984) J Neurosci , vol.4 , Issue.7 , pp. 1677-1682
    • Reppert, S.M.1    Schwartz, W.J.2
  • 8
    • 0035004799 scopus 로고    scopus 로고
    • Circadian expression of clock genes in human oral mucosa and skin: Association with specific cell-cycle phases
    • 1891949 1:CAS:528:DC%2BD3MXktVOitLk%3D 11337377
    • Bjarnason GA, Jordan RC, Wood PA, Li Q, Lincoln DW, Sothern RB, Hrushesky WJ, Ben-David Y (2001) Circadian expression of clock genes in human oral mucosa and skin: association with specific cell-cycle phases. Am J Pathol 158(5):1793-1801
    • (2001) Am J Pathol , vol.158 , Issue.5 , pp. 1793-1801
    • Bjarnason, G.A.1    Jordan, R.C.2    Wood, P.A.3    Li, Q.4    Lincoln, D.W.5    Sothern, R.B.6    Hrushesky, W.J.7    Ben-David, Y.8
  • 12
    • 0034798775 scopus 로고    scopus 로고
    • Analysis of circadian and ultradian rhythms of skin surface properties of face and forearm of healthy women
    • 11564182
    • Le Fur I, Reinberg A, Lopez S, Morizot F, Mechkouri M, Tschachler E (2001) Analysis of circadian and ultradian rhythms of skin surface properties of face and forearm of healthy women. J Invest Dermatol 117(3):718-724
    • (2001) J Invest Dermatol , vol.117 , Issue.3 , pp. 718-724
    • Le Fur, I.1    Reinberg, A.2    Lopez, S.3    Morizot, F.4    Mechkouri, M.5    Tschachler, E.6
  • 13
    • 0031951231 scopus 로고    scopus 로고
    • Time-dependent variations of the skin barrier function in humans: Transepidermal water loss, stratum corneum hydration, skin surface pH, and skin temperature
    • 1:STN:280:DyaK1c%2FosVKqtQ%3D%3D 9424081
    • Yosipovitch G, Xiong GL, Haus E, Sackett-Lundeen L, Ashkenazi I, Maibach HI (1998) Time-dependent variations of the skin barrier function in humans: transepidermal water loss, stratum corneum hydration, skin surface pH, and skin temperature. J Invest Dermatol 110(1):20-23
    • (1998) J Invest Dermatol , vol.110 , Issue.1 , pp. 20-23
    • Yosipovitch, G.1    Xiong, G.L.2    Haus, E.3    Sackett-Lundeen, L.4    Ashkenazi, I.5    Maibach, H.I.6
  • 14
    • 0025742983 scopus 로고
    • A review and mathematical analysis of circadian rhythms in cell proliferation in mouse, rat, and human epidermis
    • 1:STN:280:DyaK3Mzgt1yrsw%3D%3D 1830075
    • Brown WR (1991) A review and mathematical analysis of circadian rhythms in cell proliferation in mouse, rat, and human epidermis. J Invest Dermatol 97(2):273-280
    • (1991) J Invest Dermatol , vol.97 , Issue.2 , pp. 273-280
    • Brown, W.R.1
  • 18
    • 84878726282 scopus 로고    scopus 로고
    • Local circadian clock gates cell cycle progression of transient amplifying cells during regenerative hair cycling
    • 3677499 1:CAS:528:DC%2BC3sXhtFGktrjL 23690597
    • Plikus MV, Vollmers C, de la Cruz D, Chaix A, Ramos R, Panda S, Chuong CM (2013) Local circadian clock gates cell cycle progression of transient amplifying cells during regenerative hair cycling. Proc Natl Acad Sci USA 110(23):E2106-E2115
    • (2013) Proc Natl Acad Sci USA , vol.110 , Issue.23 , pp. 2106-E2115
    • Plikus, M.V.1    Vollmers, C.2    De La Cruz, D.3    Chaix, A.4    Ramos, R.5    Panda, S.6    Chuong, C.M.7
  • 20
  • 21
    • 79952274829 scopus 로고    scopus 로고
    • Deficiency of circadian protein CLOCK reduces lifespan and increases age-related cataract development in mice
    • 1:CAS:528:DC%2BC3MXhtVSisrY%3D
    • Dubrovsky YV, Samsa WE, Kondratov RV (2010) Deficiency of circadian protein CLOCK reduces lifespan and increases age-related cataract development in mice. Aging (Albany NY) 2(12):936-944
    • (2010) Aging (Albany NY) , vol.2 , Issue.12 , pp. 936-944
    • Dubrovsky, Y.V.1    Samsa, W.E.2    Kondratov, R.V.3
  • 22
    • 33746191906 scopus 로고    scopus 로고
    • Early aging and age-related pathologies in mice deficient in BMAL1, the core component of the circadian clock
    • 1522083 1:CAS:528:DC%2BD28XnsVyjtrY%3D 16847346
    • Kondratov RV, Kondratova AA, Gorbacheva VY, Vykhovanets OV, Antoch MP (2006) Early aging and age-related pathologies in mice deficient in BMAL1, the core component of the circadian clock. Genes Dev 20(14):1868-1873
    • (2006) Genes Dev , vol.20 , Issue.14 , pp. 1868-1873
    • Kondratov, R.V.1    Kondratova, A.A.2    Gorbacheva, V.Y.3    Vykhovanets, O.V.4    Antoch, M.P.5
  • 23
    • 0042566193 scopus 로고    scopus 로고
    • Temperature compensation and temperature resetting of circadian rhythms in mammalian cultured fibroblasts
    • 1:CAS:528:DC%2BD3sXmsFylsb8%3D 12875656
    • Tsuchiya Y, Akashi M, Nishida E (2003) Temperature compensation and temperature resetting of circadian rhythms in mammalian cultured fibroblasts. Genes Cells 8(8):713-720
    • (2003) Genes Cells , vol.8 , Issue.8 , pp. 713-720
    • Tsuchiya, Y.1    Akashi, M.2    Nishida, E.3
  • 24
    • 0027349267 scopus 로고
    • Temporal organization: Reflections of a Darwinian clock-watcher
    • 1:STN:280:DyaK3s3itFWjsg%3D%3D 8466172
    • Pittendrigh CS (1993) Temporal organization: reflections of a Darwinian clock-watcher. Annu Rev Physiol 55:16-54
    • (1993) Annu Rev Physiol , vol.55 , pp. 16-54
    • Pittendrigh, C.S.1
  • 26
    • 67449151670 scopus 로고    scopus 로고
    • Glucocorticoids and the circadian clock
    • 1:CAS:528:DC%2BD1MXjvVOgtL0%3D 18971218
    • Dickmeis T (2009) Glucocorticoids and the circadian clock. J Endocrinol 200(1):3-22
    • (2009) J Endocrinol , vol.200 , Issue.1 , pp. 3-22
    • Dickmeis, T.1
  • 27
    • 84866764731 scopus 로고    scopus 로고
    • Glucocorticoids as entraining signals for peripheral circadian oscillators
    • 3512018 1:CAS:528:DC%2BC38XhsVyqs7vP 22893723
    • Pezuk P, Mohawk JA, Wang LA, Menaker M (2012) Glucocorticoids as entraining signals for peripheral circadian oscillators. Endocrinology 153(10):4775-4783
    • (2012) Endocrinology , vol.153 , Issue.10 , pp. 4775-4783
    • Pezuk, P.1    Mohawk, J.A.2    Wang, L.A.3    Menaker, M.4
  • 28
    • 13244267262 scopus 로고    scopus 로고
    • The cutaneous serotoninergic/melatoninergic system: Securing a place under the sun
    • 1:CAS:528:DC%2BD2MXhtFenu74%3D 15677341
    • Slominski A, Wortsman J, Tobin DJ (2005) The cutaneous serotoninergic/melatoninergic system: securing a place under the sun. FASEB J 19(2):176-194
    • (2005) FASEB J , vol.19 , Issue.2 , pp. 176-194
    • Slominski, A.1    Wortsman, J.2    Tobin, D.J.3
  • 30
    • 0032834067 scopus 로고    scopus 로고
    • Organization of rat circadian rhythms during daily infusion of melatonin or S20098, a melatonin agonist
    • 1:CAS:528:DyaK1MXmt1Gisrs%3D 10484499
    • Pitrosky B, Kirsch R, Malan A, Mocaer E, Pevet P (1999) Organization of rat circadian rhythms during daily infusion of melatonin or S20098, a melatonin agonist. Am J Physiol 277(3 Pt 2):R812-R828
    • (1999) Am J Physiol , vol.277 , pp. 812-R828
    • Pitrosky, B.1    Kirsch, R.2    Malan, A.3    Mocaer, E.4    Pevet, P.5
  • 31
    • 0036458593 scopus 로고    scopus 로고
    • In the rat, exogenous melatonin increases the amplitude of pineal melatonin secretion by a direct action on the circadian clock
    • 12383238
    • Bothorel B, Barassin S, Saboureau M, Perreau S, Vivien-Roels B, Malan A, Pevet P (2002) In the rat, exogenous melatonin increases the amplitude of pineal melatonin secretion by a direct action on the circadian clock. Eur J Neurosci 16(6):1090-1098
    • (2002) Eur J Neurosci , vol.16 , Issue.6 , pp. 1090-1098
    • Bothorel, B.1    Barassin, S.2    Saboureau, M.3    Perreau, S.4    Vivien-Roels, B.5    Malan, A.6    Pevet, P.7
  • 32
    • 84897662315 scopus 로고    scopus 로고
    • Like melatonin, agomelatine (S20098) increases the amplitude of oscillations of two clock outputs: Melatonin and temperature rhythms
    • 24328729
    • Castanho A, Bothorel B, Seguin L, Mocaer E, Pevet P (2013) Like melatonin, agomelatine (S20098) increases the amplitude of oscillations of two clock outputs: melatonin and temperature rhythms. Chronobiol Int 31(3):371-381
    • (2013) Chronobiol Int , vol.31 , Issue.3 , pp. 371-381
    • Castanho, A.1    Bothorel, B.2    Seguin, L.3    Mocaer, E.4    Pevet, P.5
  • 33
    • 84858439689 scopus 로고    scopus 로고
    • Melatonin: Both master clock output and internal time-giver in the circadian clocks network
    • 21914478
    • Pevet P, Challet E (2011) Melatonin: both master clock output and internal time-giver in the circadian clocks network. J Physiol Paris 105(4-6):170-182
    • (2011) J Physiol Paris , vol.105 , Issue.4-6 , pp. 170-182
    • Pevet, P.1    Challet, E.2
  • 35
    • 16844381565 scopus 로고    scopus 로고
    • Real-time luminescence reporting of circadian gene expression in mammals
    • 3793321 1:CAS:528:DC%2BD2MXksFynsLg%3D 15817295
    • Yamazaki S, Takahashi JS (2005) Real-time luminescence reporting of circadian gene expression in mammals. Methods Enzymol 393:288-301
    • (2005) Methods Enzymol , vol.393 , pp. 288-301
    • Yamazaki, S.1    Takahashi, J.S.2
  • 36
    • 0032511229 scopus 로고    scopus 로고
    • A serum shock induces circadian gene expression in mammalian tissue culture cells
    • 1:CAS:528:DyaK1cXjvFKqsL8%3D 9635423
    • Balsalobre A, Damiola F, Schibler U (1998) A serum shock induces circadian gene expression in mammalian tissue culture cells. Cell 93(6):929-937
    • (1998) Cell , vol.93 , Issue.6 , pp. 929-937
    • Balsalobre, A.1    Damiola, F.2    Schibler, U.3
  • 38
    • 0037097753 scopus 로고    scopus 로고
    • Daily infusion of melatonin entrains circadian activity rhythms in the diurnal rodent Arvicanthis ansorgei
    • 1:CAS:528:DC%2BD38XktFKisLw%3D 12048170
    • Slotten HA, Krekling S, Sicard B, Pevet P (2002) Daily infusion of melatonin entrains circadian activity rhythms in the diurnal rodent Arvicanthis ansorgei. Behav Brain Res 133(1):11-19
    • (2002) Behav Brain Res , vol.133 , Issue.1 , pp. 11-19
    • Slotten, H.A.1    Krekling, S.2    Sicard, B.3    Pevet, P.4
  • 39
    • 22044452796 scopus 로고    scopus 로고
    • Ontogenetic development of the mammalian circadian system
    • 16021838
    • Weinert D (2005) Ontogenetic development of the mammalian circadian system. Chronobiol Int 22(2):179-205
    • (2005) Chronobiol Int , vol.22 , Issue.2 , pp. 179-205
    • Weinert, D.1
  • 40
    • 59149102190 scopus 로고    scopus 로고
    • Differential maturation of circadian rhythms in clock gene proteins in the suprachiasmatic nucleus and the pars tuberalis during mouse ontogeny
    • 2651153 19222558
    • Ansari N, Agathagelidis M, Lee C, Korf HW, von Gall C (2009) Differential maturation of circadian rhythms in clock gene proteins in the suprachiasmatic nucleus and the pars tuberalis during mouse ontogeny. Eur J Neurosci 29(3):477-489
    • (2009) Eur J Neurosci , vol.29 , Issue.3 , pp. 477-489
    • Ansari, N.1    Agathagelidis, M.2    Lee, C.3    Korf, H.W.4    Von Gall, C.5
  • 41
    • 84864813034 scopus 로고    scopus 로고
    • When does it start ticking? Ontogenetic development of the mammalian circadian system
    • 1:CAS:528:DC%2BC38XhsFGlsbjM 22877661
    • Christ E, Korf HW, von Gall C (2012) When does it start ticking? Ontogenetic development of the mammalian circadian system. Prog Brain Res 199:105-118
    • (2012) Prog Brain Res , vol.199 , pp. 105-118
    • Christ, E.1    Korf, H.W.2    Von Gall, C.3
  • 43
    • 0037016596 scopus 로고    scopus 로고
    • Ontogeny of circadian expression of serotonin N-acetyltransferase mRNA in the rat retina
    • 1:CAS:528:DC%2BD3MXptFymtLc%3D 11750995
    • Sakamoto K, Oishi K, Ishida N (2002) Ontogeny of circadian expression of serotonin N-acetyltransferase mRNA in the rat retina. Neurosci Lett 317(1):53-55
    • (2002) Neurosci Lett , vol.317 , Issue.1 , pp. 53-55
    • Sakamoto, K.1    Oishi, K.2    Ishida, N.3
  • 44
    • 33847751496 scopus 로고    scopus 로고
    • Postnatal ontogenesis of the circadian clock within the rat liver
    • 1:CAS:528:DC%2BD2sXjsVyltbg%3D 17095653
    • Sladek M, Jindrakova Z, Bendova Z, Sumova A (2007) Postnatal ontogenesis of the circadian clock within the rat liver. Am J Physiol Regul Integr Comp Physiol 292(3):R1224-R1229
    • (2007) Am J Physiol Regul Integr Comp Physiol , vol.292 , Issue.3 , pp. 1224-R1229
    • Sladek, M.1    Jindrakova, Z.2    Bendova, Z.3    Sumova, A.4
  • 46
    • 0036679063 scopus 로고    scopus 로고
    • Effects of aging on central and peripheral mammalian clocks
    • 125050 1:CAS:528:DC%2BD38Xmt1ChtLw%3D 12149444
    • Yamazaki S, Straume M, Tei H, Sakaki Y, Menaker M, Block GD (2002) Effects of aging on central and peripheral mammalian clocks. Proc Natl Acad Sci USA 99(16):10801-10806
    • (2002) Proc Natl Acad Sci USA , vol.99 , Issue.16 , pp. 10801-10806
    • Yamazaki, S.1    Straume, M.2    Tei, H.3    Sakaki, Y.4    Menaker, M.5    Block, G.D.6
  • 47
    • 0035817766 scopus 로고    scopus 로고
    • Circadian rhythms in firing rate of individual suprachiasmatic nucleus neurons from adult and middle-aged mice
    • 1:CAS:528:DC%2BD3MXmvVyjtL8%3D 11566498
    • Aujard F, Herzog ED, Block GD (2001) Circadian rhythms in firing rate of individual suprachiasmatic nucleus neurons from adult and middle-aged mice. Neuroscience 106(2):255-261
    • (2001) Neuroscience , vol.106 , Issue.2 , pp. 255-261
    • Aujard, F.1    Herzog, E.D.2    Block, G.D.3
  • 49
    • 80053102580 scopus 로고    scopus 로고
    • Disrupting the circadian clock: Gene-specific effects on aging, cancer, and other phenotypes
    • 1:CAS:528:DC%2BC3MXntleltr8%3D
    • Yu EA, Weaver DR (2011) Disrupting the circadian clock: gene-specific effects on aging, cancer, and other phenotypes. Aging (Albany NY) 3(5):479-493
    • (2011) Aging (Albany NY) , vol.3 , Issue.5 , pp. 479-493
    • Yu, E.A.1    Weaver, D.R.2
  • 50
    • 0000176434 scopus 로고
    • Studies on hair growth in the rat
    • 1273082 1:STN:280:DyaG3c%2FgsVShug%3D%3D 15394396
    • Durward A, Rudall KM (1949) Studies on hair growth in the rat. J Anat 83(4):325-335, 324 pl
    • (1949) J Anat , vol.83 , Issue.4 , pp. 325-335
    • Durward, A.1    Rudall, K.M.2
  • 51
    • 42149099447 scopus 로고    scopus 로고
    • Complex hair cycle domain patterns and regenerative hair waves in living rodents
    • 2705329 1:CAS:528:DC%2BD1cXksF2rtbs%3D 18094733
    • Plikus MV, Chuong CM (2008) Complex hair cycle domain patterns and regenerative hair waves in living rodents. J Invest Dermatol 128(5):1071-1080
    • (2008) J Invest Dermatol , vol.128 , Issue.5 , pp. 1071-1080
    • Plikus, M.V.1    Chuong, C.M.2
  • 52
    • 0026699714 scopus 로고
    • Fibroblasts in normal and pathological terminal differentiation, aging, apoptosis and transformation
    • 18647676
    • Bayreuther K, Francz PI, Rodemann HP (1992) Fibroblasts in normal and pathological terminal differentiation, aging, apoptosis and transformation. Arch Gerontol Geriatr 15(Suppl 1):47-74
    • (1992) Arch Gerontol Geriatr , vol.15 , pp. 47-74
    • Bayreuther, K.1    Francz, P.I.2    Rodemann, H.P.3
  • 54
    • 55849133399 scopus 로고    scopus 로고
    • Increased coherence of circadian rhythms in mature fibroblast cultures
    • 2735814 19060257
    • O'Neill JS, Hastings MH (2008) Increased coherence of circadian rhythms in mature fibroblast cultures. J Biol Rhythms 23(6):483-488
    • (2008) J Biol Rhythms , vol.23 , Issue.6 , pp. 483-488
    • O'Neill, J.S.1    Hastings, M.H.2
  • 55
    • 84859091952 scopus 로고    scopus 로고
    • Persistent cell-autonomous circadian oscillations in fibroblasts revealed by six-week single-cell imaging of PER2::LUC bioluminescence
    • 3315561 1:CAS:528:DC%2BC38XlsFamtbw%3D 22479387
    • Leise TL, Wang CW, Gitis PJ, Welsh DK (2012) Persistent cell-autonomous circadian oscillations in fibroblasts revealed by six-week single-cell imaging of PER2:LUC bioluminescence. PLoS ONE 7(3):e33334
    • (2012) PLoS ONE , vol.7 , Issue.3 , pp. 33334
    • Leise, T.L.1    Wang, C.W.2    Gitis, P.J.3    Welsh, D.K.4
  • 56
    • 84878891497 scopus 로고    scopus 로고
    • Fibroblast PER2 circadian rhythmicity depends on cell density
    • 3760388 1:CAS:528:DC%2BC3sXhtV2murbI 23735497
    • Noguchi T, Wang LL, Welsh DK (2013) Fibroblast PER2 circadian rhythmicity depends on cell density. J Biol Rhythms 28(3):183-192
    • (2013) J Biol Rhythms , vol.28 , Issue.3 , pp. 183-192
    • Noguchi, T.1    Wang, L.L.2    Welsh, D.K.3
  • 58
    • 0346102816 scopus 로고    scopus 로고
    • Circadian gene expression in mammalian fibroblasts revealed by real-time luminescence reporting: Temperature compensation and damping
    • 307697 1:CAS:528:DC%2BD2cXhtVGjtA%3D%3D 14657355
    • Izumo M, Johnson CH, Yamazaki S (2003) Circadian gene expression in mammalian fibroblasts revealed by real-time luminescence reporting: temperature compensation and damping. Proc Natl Acad Sci USA 100(26):16089-16094
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.26 , pp. 16089-16094
    • Izumo, M.1    Johnson, C.H.2    Yamazaki, S.3
  • 59
    • 84858321758 scopus 로고    scopus 로고
    • Simulated body temperature rhythms reveal the phase-shifting behavior and plasticity of mammalian circadian oscillators
    • 3315118 1:CAS:528:DC%2BC38XltVOnsbc%3D 22379191
    • Saini C, Morf J, Stratmann M, Gos P, Schibler U (2012) Simulated body temperature rhythms reveal the phase-shifting behavior and plasticity of mammalian circadian oscillators. Genes Dev 26(6):567-580
    • (2012) Genes Dev , vol.26 , Issue.6 , pp. 567-580
    • Saini, C.1    Morf, J.2    Stratmann, M.3    Gos, P.4    Schibler, U.5
  • 60
    • 80054940558 scopus 로고    scopus 로고
    • Thermostabilization of firefly luciferase by in vivo directed evolution
    • 1:CAS:528:DC%2BC3MXhtlGku7bI 21900306
    • Koksharov MI, Ugarova NN (2011) Thermostabilization of firefly luciferase by in vivo directed evolution. Protein Eng Des Sel 24(11):835-844
    • (2011) Protein Eng des Sel , vol.24 , Issue.11 , pp. 835-844
    • Koksharov, M.I.1    Ugarova, N.N.2
  • 62
    • 53749105877 scopus 로고    scopus 로고
    • Melatonin and the circadian entrainment of metabolic and hormonal activities in primary isolated adipocytes
    • 1:CAS:528:DC%2BD1cXhtlKhsr%2FO 18662218
    • Alonso-Vale MI, Andreotti S, Mukai PY, Borges-Silva C, Peres SB, Cipolla-Neto J, Lima FB (2008) Melatonin and the circadian entrainment of metabolic and hormonal activities in primary isolated adipocytes. J Pineal Res 45(4):422-429
    • (2008) J Pineal Res , vol.45 , Issue.4 , pp. 422-429
    • Alonso-Vale, M.I.1    Andreotti, S.2    Mukai, P.Y.3    Borges-Silva, C.4    Peres, S.B.5    Cipolla-Neto, J.6    Lima, F.B.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.