Persistent cell-autonomous circadian oscillations in fibroblasts revealed by six-week single-cell imaging of PER2::LUC bioluminescence

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  Leise, Tanya L ^a   Wang, Connie W ^b   Gitis, Paula J ^b   Welsh, David K ^b,c  

^a AMHERST COLLEGE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c VA SAN DIEGO HEALTHCARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LUCIFERASE; PER2 PROTEIN; CIRCADIAN RHYTHM SIGNALING PROTEIN; HYBRID PROTEIN; PER2 PROTEIN, MOUSE;

ANIMAL CELL; ARTICLE; BIOLOGICAL RHYTHM; BIOLUMINESCENCE; CELL ACTIVITY; CELL DIFFERENTIATION; CELL HETEROGENEITY; CELL MEMBRANE POTENTIAL; CELL POPULATION; CELL SIZE; CIRCADIAN RHYTHM; CONTROLLED STUDY; FIBROBLAST; GENE EXPRESSION; IMAGE ANALYSIS; IN VITRO STUDY; MOLECULAR CLOCK; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; OSCILLATION; OSCILLATOR; SINGLE CELL ANALYSIS; STOCHASTIC MODEL; TIME SERIES ANALYSIS; ALGORITHM; ANIMAL; BIOLOGICAL MODEL; CELL CULTURE; CYTOLOGY; GENETICS; LUMINESCENCE; METABOLISM; METHODOLOGY; STATISTICS; TIME; TRANSGENIC MOUSE;

MUS;

ALGORITHMS; ANIMALS; CELLS, CULTURED; CIRCADIAN RHYTHM; FIBROBLASTS; LUCIFERASES; LUMINESCENT MEASUREMENTS; MICE; MICE, TRANSGENIC; MODELS, BIOLOGICAL; PERIOD CIRCADIAN PROTEINS; RECOMBINANT FUSION PROTEINS; SINGLE-CELL ANALYSIS; STOCHASTIC PROCESSES; TIME FACTORS;

EID: 84859091952     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0033334     Document Type: Article

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