In the rat, exogenous melatonin increases the amplitude of pineal melatonin secretion by a direct action on the circadian clock

European Journal of Neuroscience

Volumn 16, Issue 6, 2002, Pages 1090-1098

  Bothorel, Béatrice ^a   Barassin, Stéphane ^a   Saboureau, Michel ^a   Perreau, Stéphanie ^a   Vivien Roels, Berthe ^a   Malan, André ^a   Pévet, Paul ^a  

^a UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

Circadian rhythms; Microdialysis; Nonphotic cues; Phase shift; Suprachiasmatic nuclei

Indexed keywords

MELATONIN;

ANIMAL EXPERIMENT; ARTICLE; CIRCADIAN RHYTHM; CONTROLLED STUDY; DARKNESS; IN VIVO STUDY; MALE; MICRODIALYSIS; NONHUMAN; PACEMAKER; PINEAL BODY; PRIORITY JOURNAL; RAT; SUPRACHIASMATIC NUCLEUS; SYNTHESIS; TIME;

ANIMALS; CIRCADIAN RHYTHM; DARKNESS; DOSE-RESPONSE RELATIONSHIP, DRUG; INJECTIONS, SUBCUTANEOUS; MALE; MELATONIN; MICRODIALYSIS; PHOTIC STIMULATION; PINEAL GLAND; RATS; RATS, WISTAR; REACTION TIME; SUPRACHIASMATIC NUCLEUS;

EID: 0036458593     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1460-9568.2002.02176.x     Document Type: Article

References (33)

1. Armstrong, S.M. & Chesworth, M.J. (1987) Melatonin phase-shifts a mammalian circadian clock. In Trentini, G.P., De Gachini, C. & Pévet, P. (eds), Fundamentals and Clinics in Pineal Research. Raven Press, New York, pp. 195-198.
2. Barassin, S., Saboureau, M., Kalsbeek, A., Bothorel, B., Vivien-Roels, B., Malan, A., Buijs, R.M., Guardiola-Lemaitre, B. & Pévet, P. (1999) Interindividual differences in the pattern of melatonin secretion of the Wistar rat. J. Pineal Res., 27, 193-201.
3. Benveniste, H. (1989) Brain microdialysis. J. Neurochem., 52, 1667-1679.
4. Cassone, V.M., Chesworth, M.J. & Armstrong, S.M. (1986) Dose-dependent entrainment of rat circadian rhythms by daily injection of melatonin. J. Biol. Rhythms, 1, 219-229.
5. Challet, E., Malan, A. & Pévet, P. (1996) Daily hypocaloric feeding entrains circadian rhythms of wheel-running and body temperature in rats kept in constant darkness. Neurosci. Lett., 211, 1-4.
6. Drijfhout, W.J., de Vries, J.B., Homan, E.J., Brons, H.F., Copinga, S., Gruppen, G., Beresford, I.J., Hagan, R.M., Grol, C.J. & Westerink, B.H. (1999) Novel non-indolic melatonin receptor agonists differentially entrain endogenous melatonin rhythm and increase its amplitude. Eur. J. Pharmacol., 382, 157-166.
7. Drijfhout, W.J., Grol, C.J. & Westerink, B.H. (1993) Microdialysis of melatonin in the rat pineal gland: Methodology and pharmacological applications. J. Neurochem., 61, 936-942.
8. Drijfhout, W.J., Homan, E.J., Brons, H.F., Oakley, N.R., Skingle, M., Grol, C.J. & Westerink, B.H. (1996) Exogenous melatonin entrains rhythm and reduces amplitude of endogenous melatonin: An in vivo microdialysis study. J. Pineal Res., 20, 24-32.
9. Gauer, F., Masson-Pévet, M., Skene, D.J., Vivien-Roels, B. & Pévet, P. (1993) Daily rhythms of melatonin binding sites in the rat pars tuberalis and suprachiasmatic nuclei; evidence for a regulation of melatonin receptors by melatonin itself. Neuroendocrinology, 57, 120-126.
10. Gillette, M.U. & Mitchell, J.W. (2002) Signaling in the suprachiasmatic nucleus: selectively responsive and integrative. Cell Tissue Res. 309, 99-107.
11. Humlova, M. & Illnerova, H. (1990) Melatonin entrains the circadian rhythm in the rat pineal N-acetyltransferase activity. Neuroendocrinology, 52, 196-199.
12. Humlova, M. & Illnerova, H. (1992) Entrainment of the circadian rhythm in the rat pineal N-acetyltransferase activity by melatonin is photoperiod dependent. J. Pineal Res., 13, 151-157.
13. Hunt, A.E., Al Ghoul, W.M., Gillette, M.U. & Dubocovich, M.L. (2001) Activation of MT(2) melatonin receptors in rat suprachiasmatic nucleus phase advances the circadian clock. Am. J. Physiol., 280, C110-C118.
14. Illnerova, H. & Vanecek, J. (1982) Two-oscillator structure of the pacemaker controlling the circadian rhythm of N-acetyltransferase in the rat pineal gland. J. Comp. Physiol., 145, 539-641.
15. Kalsbeek, A., Cutrera, R.A., Van Heerikhuize, J.J., van der Vliet, J. & Buijs, R.M. (1999) GABA release from suprachiasmatic nucleus terminals is necessary for the light-induced inhibition of nocturnal melatonin release in the rat. Neuroscience, 91, 453-461.
16. Liu, C., Weaver, D.R., Jin, X., Shearman, L.P., Pieschl, R.L., Gribkoff, V.K. & Reppert, S.M. (1997) Molecular dissection of two distinct actions of melatonin on the suprachiasmatic circadian clock. Neuron, 19, 91-102.
17. Masson-Pévet, M., George, D., Kalsbeek, A., Saboureau, M., Lakhdar-Ghazal, N. & Pévet, P. (1994) An attempt to correlate brain areas containing melatonin-binding sites with rhythmic functions: A study in ve hibernator species. Cell Tissue Res., 278, 97-106.
18. McArthur, A.J., Gillette, M.U. & Prosser, R.A. (1991) Melatonin directly resets the rat suprachiasmatic circadian clock in vitro. Brain Res., 565, 158-161.
19. McArthur, A.J., Hunt, A.E. & Gillette, M.U. (1997) Melatonin action and signal transduction in the rat suprachiasmatic circadian clock: Activation of protein kinase C at dusk and dawn. Endocrinology, 138, 627-634.
20. Meijer, J.H., Watanabe, K., Schaap, J., Albus, H. & Detari, L. (1998) Light responsiveness of the suprachiasmatic nucleus: Long-term multiunit and single-unit recordings in freely moving rats. J. Neurosci., 18, 9078-9087.
21. Miguez, J.M., Simonneaux, V. & Pévet, P. (1996) Changes in pineal indoleamines in rats after single melatonin injections: Evidence for a diurnal sensitivity to melatonin. J. Neuroendocrinol., 8, 611-616.
22. Morin, L.P. (1994) The circadian visual system. Brain Res., 19, 102-127.
23. Paxinos, G. & Watson, C. (1982) The Rat Brain in Stereotaxic Coordinates. Academic press, New York.
24. Pitrosky, B., Kirsch, R., Malan, A., Mocaer, E. & Pévet, P. (1999) Organization of rat circadian rhythms during daily infusion of melatonin or S20098, a melatonin agonist. Am. J. Physiol., 277, R812-R828.
25. Redman, J., Armstrong, S. & Ng, K.T. (1983) Free-running activity rhythms in the rat: Entrainment by melatonin. Science, 219, 1089-1091.
26. Shibata, S., Cassone, V.M. & Moore, R.Y. (1989) Effects of melatonin on neuronal activity in the rat suprachiasmatic nucleus in vitro. Neurosci. Lett., 97, 140-144.
27. Stehle, J., Vanecek, J. & Vollrath, L. (1989) Effects of melatonin on spontaneous electrical activity of neurons in rat suprachiasmatic nuclei: An in vitro iontophoretic study. J. Neural Transm., 78, 173-177.
28. van den Top, M., Buijs, R.M., Ruijter, M., Delagrange, P., Spanswick, D. & Hermes, M.L.H.J. (2001) Melatonin generates an outward potassium current in rat suprachiasmatic nucleus neurones in vitro independent of their circadian rhythm. Neuroscience, 107, 99-108.
29. Turek, F.W. (1989) Effects of stimulated physical activity on the circadian pacemaker of vertebrates. J. Biol. Rhythms, 4, 135-147.
30. Vanecek, J., Pavlik, A. & Illnerova, H. (1987) Hypothalamic melatonin receptor sites revealed by autoradiography. Brain Res., 435, 359-362.
31. Warren, W.S., Hodges, D.B. & Cassone, V.M. (1993) Pinealectomized rats entrain and phase-shift to melatonin injections in a dose-dependent manner. J. Biol. Rhythms, 8, 233-245.
32. Weibel, L., Rettori, M.C., Lesieur, D., Delagrange, P., Renard, P. & Van Reeth, O. (1999) A single oral dose of S 22153, a melatonin antagonist, blocks the phase advancing effects of melatonin in C3H mice. Brain Res., 829, 160-166.
33. Zaidan, R., Geoffriau, M., Brun, J., Taillard, J., Bureau, C., Chazot, G. & Claustrat, B. (1994) Melatonin is able to influence its secretion in humans: Description of a phase-response curve. Neuroendocrinology, 60, 105-112.