메뉴 건너뛰기




Volumn 242, Issue 1, 2015, Pages 230-235

FoxO1 regulates asymmetric dimethylarginine via downregulation of dimethylaminohydrolase 1 in human endothelial cells and subjects with atherosclerosis

Author keywords

ADMA; Atherosclerosis; Biomarker; Endothelium; FoxO1

Indexed keywords

DIMETHYLAMINOHYDROLASE 1; DIMETHYLARGININASE; GREEN FLUORESCENT PROTEIN; N(G),N(G) DIMETHYLARGININE; TRANSCRIPTION FACTOR FKHR; UNCLASSIFIED DRUG; AMIDASE; ARGININE; FORKHEAD TRANSCRIPTION FACTOR; FOXO1 PROTEIN, HUMAN; N,N-DIMETHYLARGININE;

EID: 84938060435     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2015.07.026     Document Type: Article
Times cited : (25)

References (39)
  • 1
    • 4544227785 scopus 로고    scopus 로고
    • Abnormal angiogenesis in Foxo1 (Fkhr)-deficient mice
    • Furuyama T., et al. Abnormal angiogenesis in Foxo1 (Fkhr)-deficient mice. J. Biol. Chem. 2004, 279:34741-34749.
    • (2004) J. Biol. Chem. , vol.279 , pp. 34741-34749
    • Furuyama, T.1
  • 2
    • 33846295218 scopus 로고    scopus 로고
    • FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis
    • Paik J.H., et al. FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis. Cell 2007, 128:309-323.
    • (2007) Cell , vol.128 , pp. 309-323
    • Paik, J.H.1
  • 3
    • 24644519938 scopus 로고    scopus 로고
    • Involvement of Foxo transcription factors in angiogenesis and postnatal neovascularization
    • Potente M., et al. Involvement of Foxo transcription factors in angiogenesis and postnatal neovascularization. J. Clin. Invest. 2005, 115:2382-2392.
    • (2005) J. Clin. Invest. , vol.115 , pp. 2382-2392
    • Potente, M.1
  • 4
    • 70349645728 scopus 로고    scopus 로고
    • Foxo1 links hyperglycemia to LDL oxidation and endothelial nitric oxide synthase dysfunction in vascular endothelial cells
    • Tanaka J., et al. Foxo1 links hyperglycemia to LDL oxidation and endothelial nitric oxide synthase dysfunction in vascular endothelial cells. Diabetes 2009, 58:2344-2354.
    • (2009) Diabetes , vol.58 , pp. 2344-2354
    • Tanaka, J.1
  • 5
    • 84860743760 scopus 로고    scopus 로고
    • FOXOs and sirtuins in vascular growth, maintenance, and aging
    • Oellerich M.F., Potente M. FOXOs and sirtuins in vascular growth, maintenance, and aging. Circ. Res. 2012, 110:1238-1251.
    • (2012) Circ. Res. , vol.110 , pp. 1238-1251
    • Oellerich, M.F.1    Potente, M.2
  • 6
    • 84858066279 scopus 로고    scopus 로고
    • FoxOs integrate pleiotropic actions of insulin in vascular endothelium to protect mice from atherosclerosis
    • Tsuchiya K., et al. FoxOs integrate pleiotropic actions of insulin in vascular endothelium to protect mice from atherosclerosis. Cell Metab. 2012, 15:372-381.
    • (2012) Cell Metab. , vol.15 , pp. 372-381
    • Tsuchiya, K.1
  • 7
    • 80052968080 scopus 로고    scopus 로고
    • Regulation of FoxO transcription factors by acetylation and protein-protein interactions
    • Daitoku H., Sakamaki J., Fukamizu A. Regulation of FoxO transcription factors by acetylation and protein-protein interactions. Biochim. Biophys. Acta 2011, 1813:1954-1960.
    • (2011) Biochim. Biophys. Acta , vol.1813 , pp. 1954-1960
    • Daitoku, H.1    Sakamaki, J.2    Fukamizu, A.3
  • 8
    • 34548289502 scopus 로고    scopus 로고
    • Dynamic FoxO transcription factors
    • Huang H., Tindall D.J. Dynamic FoxO transcription factors. J. Cell Sci. 2007, 120:2479-2487.
    • (2007) J. Cell Sci. , vol.120 , pp. 2479-2487
    • Huang, H.1    Tindall, D.J.2
  • 9
    • 27744518040 scopus 로고    scopus 로고
    • FoxO1 protects against pancreatic beta cell failure through NeuroD and MafA induction
    • Kitamura Y.I., et al. FoxO1 protects against pancreatic beta cell failure through NeuroD and MafA induction. Cell Metab. 2005, 2:153-163.
    • (2005) Cell Metab. , vol.2 , pp. 153-163
    • Kitamura, Y.I.1
  • 10
    • 12144290563 scopus 로고    scopus 로고
    • Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
    • Brunet A., et al. Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 2004, 303:2011-2015.
    • (2004) Science , vol.303 , pp. 2011-2015
    • Brunet, A.1
  • 11
    • 77956260966 scopus 로고    scopus 로고
    • Uncoupling of acetylation from phosphorylation regulates FoxO1 function independent of its subcellular localization
    • Qiang L., Banks A.S., Accili D. Uncoupling of acetylation from phosphorylation regulates FoxO1 function independent of its subcellular localization. J. Biol. Chem. 2010, 285:27396-27401.
    • (2010) J. Biol. Chem. , vol.285 , pp. 27396-27401
    • Qiang, L.1    Banks, A.S.2    Accili, D.3
  • 12
    • 84859986058 scopus 로고    scopus 로고
    • Increased atherosclerosis and endothelial dysfunction in mice bearing constitutively deacetylated alleles of Foxo1 gene
    • Qiang L., et al. Increased atherosclerosis and endothelial dysfunction in mice bearing constitutively deacetylated alleles of Foxo1 gene. J. Biol. Chem. 2012, 287:13944-13951.
    • (2012) J. Biol. Chem. , vol.287 , pp. 13944-13951
    • Qiang, L.1
  • 13
    • 84879882627 scopus 로고    scopus 로고
    • Toward new biomarkers of cardiometabolic diseases
    • Roberts L.D., Gerszten R.E. Toward new biomarkers of cardiometabolic diseases. Cell Metab. 2013, 18:43-50.
    • (2013) Cell Metab. , vol.18 , pp. 43-50
    • Roberts, L.D.1    Gerszten, R.E.2
  • 14
    • 0035185021 scopus 로고    scopus 로고
    • The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression
    • Nakae J., et al. The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression. J. Clin. Invest. 2001, 108:1359-1367.
    • (2001) J. Clin. Invest. , vol.108 , pp. 1359-1367
    • Nakae, J.1
  • 15
    • 34848838902 scopus 로고    scopus 로고
    • A Foxo/Notch pathway controls myogenic differentiation and fiber type specification
    • Kitamura T., et al. A Foxo/Notch pathway controls myogenic differentiation and fiber type specification. J. Clin. Invest. 2007, 117:2477-2485.
    • (2007) J. Clin. Invest. , vol.117 , pp. 2477-2485
    • Kitamura, T.1
  • 16
    • 33748312093 scopus 로고    scopus 로고
    • Dual role of transcription factor FoxO1 in controlling hepatic insulin sensitivity and lipid metabolism
    • Matsumoto M., et al. Dual role of transcription factor FoxO1 in controlling hepatic insulin sensitivity and lipid metabolism. J. Clin. Invest. 2006, 116:2464-2472.
    • (2006) J. Clin. Invest. , vol.116 , pp. 2464-2472
    • Matsumoto, M.1
  • 17
    • 79952741730 scopus 로고    scopus 로고
    • Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome
    • Reitman Z.J. Profiling the effects of isocitrate dehydrogenase 1 and 2 mutations on the cellular metabolome. Proc. Natl. Acad. Sci. U. S. A. 2011, 108:3270-3275.
    • (2011) Proc. Natl. Acad. Sci. U. S. A. , vol.108 , pp. 3270-3275
    • Reitman, Z.J.1
  • 18
    • 68849083050 scopus 로고    scopus 로고
    • Integrated, nontargeted ultrahigh performance liquid chromatography/electrospray ionization tandem mass spectrometry platform for the identification and relative quantification of the small-molecule complement of biological systems
    • Evans A.M., et al. Integrated, nontargeted ultrahigh performance liquid chromatography/electrospray ionization tandem mass spectrometry platform for the identification and relative quantification of the small-molecule complement of biological systems. Anal. Chem. 2009, 81:6656-6667.
    • (2009) Anal. Chem. , vol.81 , pp. 6656-6667
    • Evans, A.M.1
  • 19
    • 78649702566 scopus 로고    scopus 로고
    • Organization of GC/MS and LC/MS metabolomics data into chemical libraries
    • DeHaven C.D., et al. Organization of GC/MS and LC/MS metabolomics data into chemical libraries. J. Chem. Inf. 2010, 2:9.
    • (2010) J. Chem. Inf. , vol.2 , pp. 9
    • DeHaven, C.D.1
  • 20
    • 70350134022 scopus 로고    scopus 로고
    • MicroRNA 217 modulates endothelial cell senescence via silent information regulator 1
    • Menghini R., et al. MicroRNA 217 modulates endothelial cell senescence via silent information regulator 1. Circulation 2009, 120:1524-1532.
    • (2009) Circulation , vol.120 , pp. 1524-1532
    • Menghini, R.1
  • 21
    • 16344389891 scopus 로고    scopus 로고
    • PermutMatrix: a graphical environment to arrange gene expression profiles in optimal linear order
    • Caraux G., Pinloche S. PermutMatrix: a graphical environment to arrange gene expression profiles in optimal linear order. Bioinformatics 2005, 21:1280-1281.
    • (2005) Bioinformatics , vol.21 , pp. 1280-1281
    • Caraux, G.1    Pinloche, S.2
  • 22
    • 0026548912 scopus 로고
    • Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure
    • Vallance P., et al. Accumulation of an endogenous inhibitor of nitric oxide synthesis in chronic renal failure. Lancet 1992, 339:572-575.
    • (1992) Lancet , vol.339 , pp. 572-575
    • Vallance, P.1
  • 23
    • 84869488652 scopus 로고    scopus 로고
    • Asymmetric dimethylarginine predicts clinical outcomes in ischemic chronic heart failure
    • Hsu C.P., et al. Asymmetric dimethylarginine predicts clinical outcomes in ischemic chronic heart failure. Atherosclerosis 2012, 225:504-510.
    • (2012) Atherosclerosis , vol.225 , pp. 504-510
    • Hsu, C.P.1
  • 24
    • 81255206522 scopus 로고    scopus 로고
    • Plasma asymmetric dimethylarginine predicts death and major adverse cardiovascular events in individuals referred for coronary angiography
    • Lu T.M., et al. Plasma asymmetric dimethylarginine predicts death and major adverse cardiovascular events in individuals referred for coronary angiography. Int. J. Cardiol. 2011, 153:135-140.
    • (2011) Int. J. Cardiol. , vol.153 , pp. 135-140
    • Lu, T.M.1
  • 25
    • 79959707563 scopus 로고    scopus 로고
    • Dimethylarginine dimethylaminohydrolase-1 is the critical enzyme for degrading the cardiovascular risk factor asymmetrical dimethylarginine
    • Hu X., et al. Dimethylarginine dimethylaminohydrolase-1 is the critical enzyme for degrading the cardiovascular risk factor asymmetrical dimethylarginine. Arterioscler. Thromb. Vasc. Biol. 2011, 31:1540-1546.
    • (2011) Arterioscler. Thromb. Vasc. Biol. , vol.31 , pp. 1540-1546
    • Hu, X.1
  • 26
    • 77950975714 scopus 로고    scopus 로고
    • A novel loss-of-function DDAH1 promoter polymorphism is associated with increased susceptibility to thrombosis stroke and coronary heart disease
    • Ding H., et al. A novel loss-of-function DDAH1 promoter polymorphism is associated with increased susceptibility to thrombosis stroke and coronary heart disease. Circ. Res. 2010, 106:1145-1152.
    • (2010) Circ. Res. , vol.106 , pp. 1145-1152
    • Ding, H.1
  • 27
    • 83455230998 scopus 로고    scopus 로고
    • Pathogenic cycle between the endogenous nitric oxide synthase inhibitor asymmetrical dimethylarginine and the leukocyte-derived hemoprotein myeloperoxidase
    • Von Leitner E.C., et al. Pathogenic cycle between the endogenous nitric oxide synthase inhibitor asymmetrical dimethylarginine and the leukocyte-derived hemoprotein myeloperoxidase. Circulation 2011, 124:2735-2745.
    • (2011) Circulation , vol.124 , pp. 2735-2745
    • Von Leitner, E.C.1
  • 28
    • 77952067397 scopus 로고    scopus 로고
    • Dimethylarginine dimethylaminohydrolase overexpression ameliorates atherosclerosis in apolipoprotein E-deficient mice by lowering asymmetric dimethylarginine
    • Jacobi J., et al. Dimethylarginine dimethylaminohydrolase overexpression ameliorates atherosclerosis in apolipoprotein E-deficient mice by lowering asymmetric dimethylarginine. Am. J. Pathol. 2010, 176:2559-2570.
    • (2010) Am. J. Pathol. , vol.176 , pp. 2559-2570
    • Jacobi, J.1
  • 29
    • 84890104994 scopus 로고    scopus 로고
    • Endothelial dysfunction over the course of coronary artery disease
    • Gutiérrez E., et al. Endothelial dysfunction over the course of coronary artery disease. Eur. Heart J. 2013, 34:3175-3181.
    • (2013) Eur. Heart J. , vol.34 , pp. 3175-3181
    • Gutiérrez, E.1
  • 30
    • 80053284584 scopus 로고    scopus 로고
    • Asymptomatic carotid plaque rupture with unexpected thrombosis over a non-canonical vulnerable lesion
    • Mauriello A., et al. Asymptomatic carotid plaque rupture with unexpected thrombosis over a non-canonical vulnerable lesion. Atherosclerosis 2011, 218:356-362.
    • (2011) Atherosclerosis , vol.218 , pp. 356-362
    • Mauriello, A.1
  • 31
    • 84877827732 scopus 로고    scopus 로고
    • Asymmetric dimethylarginine (ADMA): a promising biomarker for cardiovascular disease?
    • Bouras G., et al. Asymmetric dimethylarginine (ADMA): a promising biomarker for cardiovascular disease?. Curr. Top. Med. Chem. 2013, 13:180-200.
    • (2013) Curr. Top. Med. Chem. , vol.13 , pp. 180-200
    • Bouras, G.1
  • 32
    • 77957713880 scopus 로고    scopus 로고
    • Levels of asymmetrical dimethylarginine are predictive of brachial artery flow-mediated dilation 6 years later. The Cardiovascular Risk in Young Finns Study
    • Päivä H., et al. Levels of asymmetrical dimethylarginine are predictive of brachial artery flow-mediated dilation 6 years later. The Cardiovascular Risk in Young Finns Study. Atherosclerosis 2010, 212:512-520.
    • (2010) Atherosclerosis , vol.212 , pp. 512-520
    • Päivä, H.1
  • 33
    • 80055002137 scopus 로고    scopus 로고
    • Elevated plasma asymmetric dimethylarginine level in acute myocardial infarction patients as a predictor of poor prognosis and angiographic impaired reperfusion
    • Sen N., et al. Elevated plasma asymmetric dimethylarginine level in acute myocardial infarction patients as a predictor of poor prognosis and angiographic impaired reperfusion. Atherosclerosis 2011, 219:304-310.
    • (2011) Atherosclerosis , vol.219 , pp. 304-310
    • Sen, N.1
  • 34
    • 84883312084 scopus 로고    scopus 로고
    • Diabetes mellitus-associated vascular impairment: novel circulating biomarkers and therapeutic approaches
    • Tousoulis D., et al. Diabetes mellitus-associated vascular impairment: novel circulating biomarkers and therapeutic approaches. J. Am. Coll. Cardiol. 2013, 62:667-676.
    • (2013) J. Am. Coll. Cardiol. , vol.62 , pp. 667-676
    • Tousoulis, D.1
  • 35
    • 53949087832 scopus 로고    scopus 로고
    • Arginine methylation of FOXO transcription factors inhibits their phosphorylation by Akt
    • Yamagata K., et al. Arginine methylation of FOXO transcription factors inhibits their phosphorylation by Akt. Mol. Cell. 2008, 32:221-231.
    • (2008) Mol. Cell. , vol.32 , pp. 221-231
    • Yamagata, K.1
  • 36
    • 77956188526 scopus 로고    scopus 로고
    • Effects of the novel Foxo1 inhibitor AS1708727 on plasma glucose and triglyceride levels in diabetic db/db mice
    • Tanaka H., et al. Effects of the novel Foxo1 inhibitor AS1708727 on plasma glucose and triglyceride levels in diabetic db/db mice. Eur. J. Pharmacol. 2010, 645:185-191.
    • (2010) Eur. J. Pharmacol. , vol.645 , pp. 185-191
    • Tanaka, H.1
  • 37
    • 77958127193 scopus 로고    scopus 로고
    • Discovery of novel forkhead box O1 inhibitors for treating type 2 diabetes: improvement of fasting glycemia in diabetic db/db mice
    • Nagashima T., et al. Discovery of novel forkhead box O1 inhibitors for treating type 2 diabetes: improvement of fasting glycemia in diabetic db/db mice. Mol. Pharmacol. 2010, 78:961-970.
    • (2010) Mol. Pharmacol. , vol.78 , pp. 961-970
    • Nagashima, T.1
  • 38
    • 84938103834 scopus 로고    scopus 로고
    • New insight into Metformin action: regulation of ChREBP and FoXO1 activities in endothelial cells
    • Li X., et al. New insight into Metformin action: regulation of ChREBP and FoXO1 activities in endothelial cells. Mol. Endocrinol. 2015, 10.1210/ME.2015-1090.
    • (2015) Mol. Endocrinol.
    • Li, X.1
  • 39
    • 84937575236 scopus 로고    scopus 로고
    • Drug repurposing screen identifies Foxo1-dependent angiopoietin-2 regulation in sepsis
    • Ghosh C.C., et al. Drug repurposing screen identifies Foxo1-dependent angiopoietin-2 regulation in sepsis. Crit. Care Med. 2015, 43:e230-240.
    • (2015) Crit. Care Med. , vol.43 , pp. e230-240
    • Ghosh, C.C.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.