SDF-1alpha concentration dependent modulation of RhoA and Rac1 modifies breast cancer and stromal cells interaction

BMC Cancer

Volumn 15, Issue 1, 2015, Pages

  Pasquier, Jennifer ^a,b   Abu Kaoud, Nadine ^a   Abdesselem, Houari ^a   Madani, Aisha ^a   Hoarau Véchot, Jessica ^a   Thawadi, Hamda Al ^a   Vidal, Fabien ^a   Couderc, Bettina ^c   Favre, Gilles ^d   Rafii, Arash ^a,b,e  

^a WEILL CORNELL MEDICAL COLLEGE   (Qatar)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c INSTITUT CLAUDIUS REGAUD   (France)

^d CANCER RESEARCH CENTER OF TOULOUSE   (France)

^e UNIV MONTPELLIER   (France)

Author keywords

Breast cancer; Metastasis; SDF 1alpha; Stromal cells; Tumor microenvironment

Indexed keywords

BETA1 INTEGRIN; BETA3 INTEGRIN; CD51 ANTIGEN; CHEMOKINE RECEPTOR CXCR4; PROTEIN CDC42; RAC1 PROTEIN; RHO GUANINE NUCLEOTIDE BINDING PROTEIN; RHO KINASE; ROCK2 PROTEIN; STROMAL CELL DERIVED FACTOR 1ALPHA; UNCLASSIFIED DRUG; CXCL12 PROTEIN, HUMAN; RAC1 PROTEIN, HUMAN; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; RHOA PROTEIN, HUMAN; STROMAL CELL DERIVED FACTOR 1;

ARTICLE; BREAST CANCER; CELL ADHESION; CELL INTERACTION; CELL MIGRATION; CELL PROLIFERATION; CHEMOTAXIS; CONTROLLED STUDY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; PLASTICITY; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN SECRETION; PROTEIN SYNTHESIS; STROMA CELL; TIGHT JUNCTION; TUMOR INVASION; UPREGULATION; BREAST TUMOR; CELL MOTION; COCULTURE; CYTOLOGY; FEMALE; MCF-7 CELL LINE; METABOLISM; PHYSIOLOGY; TUMOR CELL LINE;

BREAST NEOPLASMS; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; CHEMOKINE CXCL12; COCULTURE TECHNIQUES; FEMALE; HUMANS; MCF-7 CELLS; RAC1 GTP-BINDING PROTEIN; RHOA GTP-BINDING PROTEIN; STROMAL CELLS;

EID: 84938055758     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/s12885-015-1556-7     Document Type: Article

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