Tau reduction diminishes spatial learning and memory deficits after mild repetitive traumatic brain injury in mice

PLoS ONE

Volumn 9, Issue 12, 2014, Pages

  Cheng, Jason S ^a,b   Craft, Ryan ^a   Yu, Gui Qiu ^a   Ho, Kaitlyn ^a   Wang, Xin ^a   Mohan, Geetha ^b   Mangnitsky, Sergey ^b   Ponnusamy, Ravikumar ^a   Mucke, Lennart ^a,b  

^a GLADSTONE INSTITUTE OF NEUROLOGICAL DISEASE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TAU PROTEIN; MAPT PROTEIN, MOUSE;

ALLELE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY; ARTICLE; BARNES MAZE TEST; BEHAVIOR; BEHAVIOR DISORDER; BRAIN CORTEX; BRAIN TISSUE; C57BL 6 MOUSE; CONTROLLED STUDY; CORPUS CALLOSUM; DEPRESSION; ELEVATED PLUS MAZE TEST; FEAR; FEMALE; FORCED SWIM TEST; FRONTAL CORTEX; HISTOPATHOLOGY; LEARNING DISORDER; LOCOMOTION; MALE; MEMORY DISORDER; MOUSE; NEUROLOGIC DISEASE; NEUROPATHY; NEUROPROTECTION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OPEN FIELD TEST; SPATIAL LEARNING; SPATIAL MEMORY; TISSUE SECTION; TRAUMATIC BRAIN INJURY; WILD TYPE MOUSE; ANIMAL; AXON; BRAIN INJURY; C57BL MOUSE; DISEASE MODEL; GENETICS; KNOCKOUT MOUSE; MAZE TEST; MEMORY; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALIA; MUS;

ANIMALS; AXONS; BRAIN INJURIES; CORPUS CALLOSUM; DISEASE MODELS, ANIMAL; FEMALE; MAGNETIC RESONANCE IMAGING; MALE; MAZE LEARNING; MEMORY; MEMORY DISORDERS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; SPATIAL LEARNING; TAU PROTEINS;

EID: 84937983333     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0115765     Document Type: Article

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