Secreted frizzled-related protein 5 (Sfrp5) decreases hepatic stellate cell activation and liver fibrosis

Liver International

Volumn 35, Issue 8, 2015, Pages 2017-2026

  Chatani, Norihiro ^a   Kamada, Yoshihiro ^a   Kizu, Takashi ^a   Ogura, Satoshi ^a   Furuta, Kunimaro ^a   Egawa, Mayumi ^a   Hamano, Mina ^a   Ezaki, Hisao ^a   Kiso, Shinichi ^a   Shimono, Akihiko ^b   Ouchi, Noriyuki ^c   Yoshida, Yuichi ^a   Takehara, Tetsuo ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b TransGenic Inc   (Japan)

^c NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

liver fibrosis; Hepatic stellate cell; JNK; Sfrp5; Wnt5a

Indexed keywords

CARBON TETRACHLORIDE; HYDROXYPROLINE; MITOMYCIN; OLIVE OIL; SECRETED FRIZZLED RELATED PROTEIN 2; SECRETED FRIZZLED RELATED PROTEIN 5; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; WNT5A PROTEIN; SFRP5 PROTEIN, MOUSE; SIGNAL PEPTIDE; WNT PROTEIN; WNT5A PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ACTIVATION; CELL MIGRATION; CELL PROLIFERATION; CHOLESTEROL DIET; CONTROLLED STUDY; DOWN REGULATION; ENZYME PHOSPHORYLATION; GENE EXPRESSION; IN VITRO STUDY; IN VIVO STUDY; LIVER FIBROSIS; LIVER INJURY; LIVER WEIGHT; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STELLATE CELL; WESTERN BLOTTING; WHITE ADIPOSE TISSUE; WST ASSAY; ANALYSIS OF VARIANCE; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL MOTION; COMPARATIVE STUDY; DISEASE MODEL; HUMAN; KNOCKOUT MOUSE; LIVER CIRRHOSIS; MALE; METABOLISM; NONPARAMETRIC TEST; PATHOLOGY; PHYSIOLOGY; RANDOMIZATION; SENSITIVITY AND SPECIFICITY;

ANALYSIS OF VARIANCE; ANIMALS; CARBON TETRACHLORIDE; CELL MOVEMENT; CELL PROLIFERATION; CELLS, CULTURED; DISEASE MODELS, ANIMAL; HEPATIC STELLATE CELLS; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LIVER CIRRHOSIS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RANDOM ALLOCATION; SENSITIVITY AND SPECIFICITY; SIGNAL TRANSDUCTION; STATISTICS, NONPARAMETRIC; WNT PROTEINS;

EID: 84937974802     PISSN: 14783223     EISSN: 14783231     Source Type: Journal    
DOI: 10.1111/liv.12757     Document Type: Article

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