Ubiquitin C-terminal hydrolase-L1 increases cancer cell invasion by modulating hydrogen peroxide generated via NADPH oxidase 4

Oncotarget

Volumn 6, Issue 18, 2015, Pages 16287-16303

  Kim, Hyun Jung ^a   Magesh, Venkataraman ^a   Lee, Jae Jin ^a   Kim, Sun ^a   Knaus, Ulla G ^b   Lee, Kong Joo ^a  

^a Ewha Womans University   (South Korea)

^b UNIVERSITY COLLEGE DUBLIN   (Ireland)

Author keywords

Hydrogen peroxide; Invasion; NOX4; Ubiquitination; UCH L1

Indexed keywords

CATALASE; HYDROGEN PEROXIDE; OXIDOREDUCTASE INHIBITOR; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 4; SMALL INTERFERING RNA; UBIQUITIN THIOLESTERASE; UBIQUITIN THIOLESTERASE L1; UNCLASSIFIED DRUG; MESSENGER RNA; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; UBIQUITIN; UCHL1 PROTEIN, HUMAN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL INVASION; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; ENZYME ACTIVITY; HELA CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LUNG METASTASIS; MALE; MELANOMA CELL LINE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TUMOR INVASION; UBIQUITINATION; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; APOPTOSIS; C57BL MOUSE; CELL MOTION; CELL PROLIFERATION; DRUG SCREENING; ELECTROSPRAY MASS SPECTROMETRY; ENZYME IMMUNOASSAY; EXPERIMENTAL MELANOMA; GENETICS; IMMUNOPRECIPITATION; LUNG TUMOR; METABOLISM; NUDE MOUSE; PATHOLOGY; PHYSIOLOGY; PROTEIN PROCESSING; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SECONDARY; TANDEM MASS SPECTROMETRY; TUMOR CELL CULTURE; WESTERN BLOTTING;

ANIMALS; APOPTOSIS; BLOTTING, WESTERN; CATALASE; CELL MOVEMENT; CELL PROLIFERATION; HELA CELLS; HUMANS; HYDROGEN PEROXIDE; IMMUNOENZYME TECHNIQUES; IMMUNOPRECIPITATION; LUNG NEOPLASMS; MALE; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; MICE, NUDE; NADPH OXIDASE; NEOPLASM INVASIVENESS; PROTEIN PROCESSING, POST-TRANSLATIONAL; REACTIVE OXYGEN SPECIES; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, SMALL INTERFERING; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; TANDEM MASS SPECTROMETRY; TUMOR CELLS, CULTURED; UBIQUITIN; UBIQUITIN THIOLESTERASE; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84937942455     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.3843     Document Type: Article

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