메뉴 건너뛰기




Volumn 5, Issue 6, 2014, Pages 1554-1564

RhoGDI2 promotes epithelial-mesenchymal transition via induction of Snail in gastric cancer cells

Author keywords

Emt; Gastric cancer; Invasion; Rhogdi2; Snail

Indexed keywords

BETA CATENIN; FIBRONECTIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; RAC1 PROTEIN; RHO GUANINE NUCLEOTIDE DISSOCIATION INHIBITOR 2; RNA; TRANSCRIPTION FACTOR SNAIL; UVOMORULIN; VIMENTIN; ANTINEOPLASTIC AGENT; ARHGDIB PROTEIN, HUMAN; CADHERIN; MESSENGER RNA; SMALL INTERFERING RNA; SNAIL FAMILY TRANSCRIPTION FACTORS; TRANSCRIPTION FACTOR;

EID: 84904264539     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.1733     Document Type: Article
Times cited : (33)

References (50)
  • 2
    • 23944518413 scopus 로고    scopus 로고
    • RhoGDI: multiple functions in the regulation of Rho family GTPase activities
    • Dovas A, Couchman J.R. RhoGDI: multiple functions in the regulation of Rho family GTPase activities. Biochem J. 2005; 390: 1-9.
    • (2005) Biochem J , vol.390 , pp. 1-9
    • Dovas, A.1    Couchman, J.R.2
  • 3
    • 21744432683 scopus 로고    scopus 로고
    • GDIs: central regulatory molecules in Rho GTPase activation
    • DerMardirossian C, Bokoch GM. GDIs: central regulatory molecules in Rho GTPase activation. Trends Cell Biol. 2005; 15: 356-363.
    • (2005) Trends Cell Biol , vol.15 , pp. 356-363
    • DerMardirossian, C.1    Bokoch, G.M.2
  • 4
    • 0026496258 scopus 로고
    • A GDP dissociation inhibitor that serves as a GTPase inhibitor for the Ras-like protein CDC42Hs
    • Hart MJ, Maru Y, Leonard D, Witte ON, Evans T, Cerione RA. A GDP dissociation inhibitor that serves as a GTPase inhibitor for the Ras-like protein CDC42Hs. Science. 1992; 258: 812-815.
    • (1992) Science , vol.258 , pp. 812-815
    • Hart, M.J.1    Maru, Y.2    Leonard, D.3    Witte, O.N.4    Evans, T.5    Cerione, R.A.6
  • 5
    • 0027393663 scopus 로고
    • GDP dissociation inhibitor prevents intrinsic and GTPase activating protein-stimulated GTP hydrolysis by the Rac GTP-binding protein
    • Chuang TH, Xu X, Knaus UG, Hart MJ, Bokoch GM. GDP dissociation inhibitor prevents intrinsic and GTPase activating protein-stimulated GTP hydrolysis by the Rac GTP-binding protein. J Biol Chem. 1993; 268: 775-778.
    • (1993) J Biol Chem , vol.268 , pp. 775-778
    • Chuang, T.H.1    Xu, X.2    Knaus, U.G.3    Hart, M.J.4    Bokoch, G.M.5
  • 8
    • 2542606977 scopus 로고    scopus 로고
    • Reduced expression of metastasis suppressor RhoGDI2 is associated with decreased survival for patients with bladder cancer
    • Theodorescu D, Sapinoso LM, Conaway MR, Oxford G, Hampton GM, Frierson HF Jr. Reduced expression of metastasis suppressor RhoGDI2 is associated with decreased survival for patients with bladder cancer. Clin Cancer Res. 2004; 10: 3800-3806.
    • (2004) Clin Cancer Res , vol.10 , pp. 3800-3806
    • Theodorescu, D.1    Sapinoso, L.M.2    Conaway, M.R.3    Oxford, G.4    Hampton, G.M.5    Frierson Jr, H.F.6
  • 10
    • 33745233810 scopus 로고    scopus 로고
    • D4-GDI, a Rho GTPase regulator, promotes breast cancer cell invasiveness
    • Zhang Y, Zhang B. D4-GDI, a Rho GTPase regulator, promotes breast cancer cell invasiveness. Cancer Res. 2006; 66: 5592-5598.
    • (2006) Cancer Res , vol.66 , pp. 5592-5598
    • Zhang, Y.1    Zhang, B.2
  • 12
    • 0344845003 scopus 로고    scopus 로고
    • Epithelial-mesenchymal transitions in development and pathologies
    • Thiery JP. Epithelial-mesenchymal transitions in development and pathologies. Curr Opin Cell Biol. 2003; 15: 740-746.
    • (2003) Curr Opin Cell Biol , vol.15 , pp. 740-746
    • Thiery, J.P.1
  • 13
    • 42249109021 scopus 로고    scopus 로고
    • Synergistic effect between EGF and TGF-beta1 in inducing oncogenic properties of intestinal epithelial cells
    • Uttamsingh S, Bao X, Nguyen KT, Bhanot M, Gong J, Chan JL, Liu F, Chu TT, Wang LH. Synergistic effect between EGF and TGF-beta1 in inducing oncogenic properties of intestinal epithelial cells. Oncogene. 2008; 27: 2626-2634.
    • (2008) Oncogene , vol.27 , pp. 2626-2634
    • Uttamsingh, S.1    Bao, X.2    Nguyen, K.T.3    Bhanot, M.4    Gong, J.5    Chan, J.L.6    Liu, F.7    Chu, T.T.8    Wang, L.H.9
  • 14
    • 0035899466 scopus 로고    scopus 로고
    • IGF-II induces rapid beta-catenin relocation to the nucleus during epithelium to mesenchyme transition
    • Morali OG, Delmas V, Moore R, Jeanney C, Thiery JP, Larue L. IGF-II induces rapid beta-catenin relocation to the nucleus during epithelium to mesenchyme transition. Oncogene. 2001; 20: 4942-4950.
    • (2001) Oncogene , vol.20 , pp. 4942-4950
    • Morali, O.G.1    Delmas, V.2    Moore, R.3    Jeanney, C.4    Thiery, J.P.5    Larue, L.6
  • 18
    • 0037326569 scopus 로고    scopus 로고
    • The transcription factor slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors
    • Bolós V, Peinado H, Pérez-Moreno MA, Fraga MF, Esteller M, Cano A. The transcription factor slug represses E-cadherin expression and induces epithelial to mesenchymal transitions: a comparison with Snail and E47 repressors. J Cell Sci. 2003; 116: 499-511.
    • (2003) J Cell Sci , vol.116 , pp. 499-511
    • Bolós, V.1    Peinado, H.2    Pérez-Moreno, M.A.3    Fraga, M.F.4    Esteller, M.5    Cano, A.6
  • 20
    • 21244437500 scopus 로고    scopus 로고
    • Expression of the transcription factors snail, slug, and twist and their clinical significance in human breast cancer
    • Martin TA, Goyal A, Watkins G, Jiang WG. Expression of the transcription factors snail, slug, and twist and their clinical significance in human breast cancer. Ann Surg Oncol. 2005; 12: 488-496.
    • (2005) Ann Surg Oncol , vol.12 , pp. 488-496
    • Martin, T.A.1    Goyal, A.2    Watkins, G.3    Jiang, W.G.4
  • 23
    • 62149103291 scopus 로고    scopus 로고
    • Prognostic importance of epithelial-mesenchymal transition-related protein expression in gastric carcinoma
    • Kim MA, Lee HS, Lee HE, Kim JH, Yang HK, Kim WH. Prognostic importance of epithelial-mesenchymal transition-related protein expression in gastric carcinoma. Histopathology. 2009; 54: 442-451.
    • (2009) Histopathology , vol.54 , pp. 442-451
    • Kim, M.A.1    Lee, H.S.2    Lee, H.E.3    Kim, J.H.4    Yang, H.K.5    Kim, W.H.6
  • 26
    • 84863481932 scopus 로고    scopus 로고
    • Twist expression associated with the epithelial-mesenchymal transition in gastric cancer
    • Liu AN, Zhu ZH, Chang SJ, Hang XS. Twist expression associated with the epithelial-mesenchymal transition in gastric cancer. Mol Cell Biochem. 2012; 367: 195-203.
    • (2012) Mol Cell Biochem , vol.367 , pp. 195-203
    • Liu, A.N.1    Zhu, Z.H.2    Chang, S.J.3    Hang, X.S.4
  • 29
    • 84872787452 scopus 로고    scopus 로고
    • Possible regulatory role of Snail in NF-κB-mediated changes in E-cadherin in gastric cancer
    • Hu Z, Liu X, Tang Z, Zhou Y, Qiao L. Possible regulatory role of Snail in NF-κB-mediated changes in E-cadherin in gastric cancer. Oncol Rep. 2012; 29: 993-1000.
    • (2012) Oncol Rep , vol.29 , pp. 993-1000
    • Hu, Z.1    Liu, X.2    Tang, Z.3    Zhou, Y.4    Qiao, L.5
  • 30
    • 67649675530 scopus 로고    scopus 로고
    • Silencing of D4-GDI inhibits growth and invasive behavior in MDAMB-231 cells by activation of Rac-dependent p38 and JNK signalling
    • Zhang Y, Rivera Rosado LA, Moon SY, Zhang B. Silencing of D4-GDI inhibits growth and invasive behavior in MDAMB-231 cells by activation of Rac-dependent p38 and JNK signalling. J Biol Chem. 2009; 284: 12956-12965.
    • (2009) J Biol Chem , vol.284 , pp. 12956-12965
    • Zhang, Y.1    Rivera Rosado, L.A.2    Moon, S.Y.3    Zhang, B.4
  • 31
    • 66149117890 scopus 로고    scopus 로고
    • Rho GDP dissociation inhibitor 2 suppresses metastasis via unconventional regulation of Rho GTPases
    • Moissoglu K, McRoberts KS, Meier JA, Theodorescu D, Schwartz MA. Rho GDP dissociation inhibitor 2 suppresses metastasis via unconventional regulation of Rho GTPases. Cancer Res. 2009; 69: 2838-2844.
    • (2009) Cancer Res , vol.69 , pp. 2838-2844
    • Moissoglu, K.1    McRoberts, K.S.2    Meier, J.A.3    Theodorescu, D.4    Schwartz, M.A.5
  • 36
    • 34447331032 scopus 로고    scopus 로고
    • Expression of snail in pancreatic cancer promotes metastasis and chemoresistance
    • Yin T, Wang C, Liu T, Zhao G, Zha Y, Yang M. Expression of snail in pancreatic cancer promotes metastasis and chemoresistance. J Surg Res. 2007; 141: 196-203.
    • (2007) J Surg Res , vol.141 , pp. 196-203
    • Yin, T.1    Wang, C.2    Liu, T.3    Zhao, G.4    Zha, Y.5    Yang, M.6
  • 37
    • 52149095811 scopus 로고    scopus 로고
    • Knockdown of Snail, a novel zinc finger transcription factor, via RNA interference increases A549 cell sensitivity to cisplatin via JNK/mitochondrial pathway
    • Zhuo W, Wang Y, Zhuo X, Zhang Y, Ao X, Chen Z. Knockdown of Snail, a novel zinc finger transcription factor, via RNA interference increases A549 cell sensitivity to cisplatin via JNK/mitochondrial pathway. Lung Cancer. 2008; 62: 8-14.
    • (2008) Lung Cancer , vol.62 , pp. 8-14
    • Zhuo, W.1    Wang, Y.2    Zhuo, X.3    Zhang, Y.4    Ao, X.5    Chen, Z.6
  • 39
    • 84878583653 scopus 로고    scopus 로고
    • Overexpression of snail induces epithelial-mesenchymal transition and a cancer stem cell-like phenotype in human colorectal cancer cells
    • Fan F, Samuel S, Evans KW, Lu J, Xia L, Zhou Y, Sceusi E, Tozzi F, Ye XC, Mani SA, Ellis LM. Overexpression of snail induces epithelial-mesenchymal transition and a cancer stem cell-like phenotype in human colorectal cancer cells. Cancer Med. 2012; 1: 5-16.
    • (2012) Cancer Med , vol.1 , pp. 5-16
    • Fan, F.1    Samuel, S.2    Evans, K.W.3    Lu, J.4    Xia, L.5    Zhou, Y.6    Sceusi, E.7    Tozzi, F.8    Ye, X.C.9    Mani, S.A.10    Ellis, L.M.11
  • 41
    • 0034842795 scopus 로고    scopus 로고
    • The relationship of BRMS1 and RhoGDI2 gene expression to metastatic potential in lineage related human bladder cancer cell lines
    • Seraj MJ, Harding MA, Gildea JJ, Welch DR, Theodorescu D. The relationship of BRMS1 and RhoGDI2 gene expression to metastatic potential in lineage related human bladder cancer cell lines. Clin Exp Metastasis. 2000; 18: 519-525.
    • (2000) Clin Exp Metastasis , vol.18 , pp. 519-525
    • Seraj, M.J.1    Harding, M.A.2    Gildea, J.J.3    Welch, D.R.4    Theodorescu, D.5
  • 43
    • 84891918707 scopus 로고    scopus 로고
    • EI24 regulates epithelial-to-mesenchymal transition and tumor progression by suppressing TRAF2-mediated NF-κB activity
    • Choi JM, Devkota S, Sung YH, Lee HW. EI24 regulates epithelial-to-mesenchymal transition and tumor progression by suppressing TRAF2-mediated NF-κB activity. Oncotarget. 2013; 4: 2383-2396.
    • (2013) Oncotarget , vol.4 , pp. 2383-2396
    • Choi, J.M.1    Devkota, S.2    Sung, Y.H.3    Lee, H.W.4
  • 44
    • 45149092780 scopus 로고    scopus 로고
    • NF-kappaB and epithelial to mesenchymal transition of cancer
    • Min C, Eddy SF, Sherr DH, Sonenshein GE. NF-kappaB and epithelial to mesenchymal transition of cancer. J Cell Biochem. 2008; 104: 733-744.
    • (2008) J Cell Biochem , vol.104 , pp. 733-744
    • Min, C.1    Eddy, S.F.2    Sherr, D.H.3    Sonenshein, G.E.4
  • 45
    • 12144266241 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 is an endogenous inhibitor of snail transcription: implications for the epithelial-mesenchymal transition
    • Bachelder RE, Yoon SO, Franci C, de Herreros AG, Mercurio AM. Glycogen synthase kinase-3 is an endogenous inhibitor of snail transcription: implications for the epithelial-mesenchymal transition. J Cell Biol. 2005; 168: 29-33.
    • (2005) J Cell Biol , vol.168 , pp. 29-33
    • Bachelder, R.E.1    Yoon, S.O.2    Franci, C.3    de Herreros, A.G.4    Mercurio, A.M.5
  • 46
    • 34147193818 scopus 로고    scopus 로고
    • Constitutively active type I insulin-like growth factor receptor causes transformation and xenograft growth of immortalized mammary epithelial cells and is accompanied by an epithelial-to-mesenchymal transition mediated by NF-kappaB and snail
    • Kim HJ, Litzenburger BC, Cui X, Delgado DA, Grabiner BC, Lin X, Lewis MT, Gottardis MM, Wong TW, Attar RM, Carboni JM, Lee AV. Constitutively active type I insulin-like growth factor receptor causes transformation and xenograft growth of immortalized mammary epithelial cells and is accompanied by an epithelial-to-mesenchymal transition mediated by NF-kappaB and snail. Mol Cell Biol. 2007; 27: 3165-3175.
    • (2007) Mol Cell Biol , vol.27 , pp. 3165-3175
    • Kim, H.J.1    Litzenburger, B.C.2    Cui, X.3    Delgado, D.A.4    Grabiner, B.C.5    Lin, X.6    Lewis, M.T.7    Gottardis, M.M.8    Wong, T.W.9    Attar, R.M.10    Carboni, J.M.11    Lee, A.V.12
  • 49
    • 0033053617 scopus 로고    scopus 로고
    • Reactive oxygen intermediatedependent NF-kappaB activation by interleukin-1beta requires 5-lipoxygenase or NADPH oxidase activity
    • Bonizzi G, Piette J, Schoonbroodt S, Greimers R, Havard L, Merville MP, Bours V. Reactive oxygen intermediatedependent NF-kappaB activation by interleukin-1beta requires 5-lipoxygenase or NADPH oxidase activity. Mol Cell Biol. 1999; 19: 1950-60.
    • (1999) Mol Cell Biol , vol.19 , pp. 1950-1960
    • Bonizzi, G.1    Piette, J.2    Schoonbroodt, S.3    Greimers, R.4    Havard, L.5    Merville, M.P.6    Bours, V.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.