메뉴 건너뛰기




Volumn 126, Issue 2, 2015, Pages 195-202

Mutations in CHD2 cause defective association with active chromatin in chronic lymphocytic leukemia

Author keywords

[No Author keywords available]

Indexed keywords

CHROMATIN HELICASE DNA BINDING PROTEIN 2; DNA BINDING PROTEIN; TRANSCRIPTOME; UNCLASSIFIED DRUG; CHD2 PROTEIN, HUMAN; CHROMATIN;

EID: 84937918437     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2014-10-604959     Document Type: Article
Times cited : (48)

References (50)
  • 1
    • 84867154468 scopus 로고    scopus 로고
    • Molecular pathogenesis of chronic lymphocytic leukemia
    • Gaidano G, Fòa R, Dalla-Favera R. Molecular pathogenesis of chronic lymphocytic leukemia. J Clin Invest. 2012;122(10):3432-3438.
    • (2012) J Clin Invest. , vol.122 , Issue.10 , pp. 3432-3438
    • Gaidano, G.1    Fòa, R.2    Dalla-Favera, R.3
  • 4
    • 0033567907 scopus 로고    scopus 로고
    • Unmutated Ig V(H)genes are associated with a more aggressive form of chronic lymphocytic leukemia
    • Hamblin TJ, Davis Z, Gardiner A, Oscier DG, Stevenson FK. Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia. Blood. 1999;94(6): 1848-1854.
    • (1999) Blood. , vol.94 , Issue.6 , pp. 1848-1854
    • Hamblin, T.J.1    Davis, Z.2    Gardiner, A.3    Oscier, D.G.4    Stevenson, F.K.5
  • 5
    • 0033567968 scopus 로고    scopus 로고
    • Ig v gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia
    • Damle RN, Wasil T, Fais F, et al. Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia. Blood. 1999;94(6):1840-1847.
    • (1999) Blood. , vol.94 , Issue.6 , pp. 1840-1847
    • Damle, R.N.1    Wasil, T.2    Fais, F.3
  • 6
    • 0037406968 scopus 로고    scopus 로고
    • ZAP-70 expression as a surrogate for immunoglobulinvariable-region mutations in chronic lymphocytic leukemia
    • Crespo M, Bosch F, Villamor N, et al. ZAP-70 expression as a surrogate for immunoglobulinvariable-region mutations in chronic lymphocytic leukemia. N Engl J Med. 2003;348(18): 1764-1775.
    • (2003) N Engl J Med. , vol.348 , Issue.18 , pp. 1764-1775
    • Crespo, M.1    Bosch, F.2    Villamor, N.3
  • 7
    • 0034727833 scopus 로고    scopus 로고
    • Genomic aberrations and survival in chronic lymphocytic leukemia
    • Döhner H, Stilgenbauer S, Benner A, et al. Genomic aberrations and survival in chronic lymphocytic leukemia. N Engl J Med. 2000; 343(26):1910-1916.
    • (2000) N Engl J Med. , vol.343 , Issue.26 , pp. 1910-1916
    • Döhner, H.1    Stilgenbauer, S.2    Benner, A.3
  • 8
    • 38349084386 scopus 로고    scopus 로고
    • Relevance of CD49d protein expression as overall survival and progressive disease prognosticator in chronic lymphocytic leukemia
    • Gattei V, Bulian P, Del Principe MI, et al. Relevance of CD49d protein expression as overall survival and progressive disease prognosticator in chronic lymphocytic leukemia. Blood. 2008; 111(2):865-873.
    • (2008) Blood. , vol.111 , Issue.2 , pp. 865-873
    • Gattei, V.1    Bulian, P.2    Del Principe, M.I.3
  • 9
    • 79960036578 scopus 로고    scopus 로고
    • Wholegenome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia
    • Puente XS, Pinyol M, Quesada V, et al. Wholegenome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia. Nature. 2011; 475(7354):101-105.
    • (2011) Nature. , vol.475 , Issue.7354 , pp. 101-105
    • Puente, X.S.1    Pinyol, M.2    Quesada, V.3
  • 10
    • 84555171449 scopus 로고    scopus 로고
    • Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia
    • Quesada V, Conde L, Villamor N, et al. Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia. Nat Genet. 2012;44(1):47-52.
    • (2012) Nat Genet. , vol.44 , Issue.1 , pp. 47-52
    • Quesada, V.1    Conde, L.2    Villamor, N.3
  • 11
    • 79960353160 scopus 로고    scopus 로고
    • Analysis of the chronic lymphocytic leukemia coding genome: Role of NOTCH1 mutational activation
    • Fabbri G, Rasi S, Rossi D, et al. Analysis of the chronic lymphocytic leukemia coding genome: Role of NOTCH1 mutational activation. J Exp Med. 2011;208(7):1389-1401.
    • (2011) J Exp Med. , vol.208 , Issue.7 , pp. 1389-1401
    • Fabbri, G.1    Rasi, S.2    Rossi, D.3
  • 12
    • 84862854953 scopus 로고    scopus 로고
    • Chronic lymphocytic leukemia with SF3B1 mutation
    • Quesada V, Ramsay AJ, Lopez-Otin C. Chronic lymphocytic leukemia with SF3B1 mutation. N Engl J Med. 2012;366(26):2530.
    • (2012) N Engl J Med. , vol.366 , Issue.26 , pp. 2530
    • Quesada, V.1    Ramsay, A.J.2    Lopez-Otin, C.3
  • 13
    • 84855370035 scopus 로고    scopus 로고
    • SF3B1 and other novel cancer genes in chronic lymphocytic leukemia
    • Wang L, Lawrence MS, Wan Y, et al. SF3B1 and other novel cancer genes in chronic lymphocytic leukemia. N Engl J Med. 2011;365(26): 2497-2506.
    • (2011) N Engl J Med. , vol.365 , Issue.26 , pp. 2497-2506
    • Wang, L.1    Lawrence, M.S.2    Wan, Y.3
  • 14
    • 84878551940 scopus 로고    scopus 로고
    • POT1 mutations cause telomere dysfunction in chronic lymphocytic leukemia
    • Ramsay AJ, Quesada V, Foronda M, et al. POT1 mutations cause telomere dysfunction in chronic lymphocytic leukemia. Nat Genet. 2013;45(5): 526-530.
    • (2013) Nat Genet. , vol.45 , Issue.5 , pp. 526-530
    • Ramsay, A.J.1    Quesada, V.2    Foronda, M.3
  • 15
    • 84877894013 scopus 로고    scopus 로고
    • Functional analysis of sucrase-isomaltase mutations from chronic lymphocytic leukemia patients
    • Rodŕ?guez D, Ramsay AJ, Quesada V, et al. Functional analysis of sucrase-isomaltase mutations from chronic lymphocytic leukemia patients. Hum Mol Genet. 2013;22(11): 2273-2282.
    • (2013) Hum Mol Genet. , vol.22 , Issue.11 , pp. 2273-2282
    • Rodŕguez, D.1    Ramsay, A.J.2    Quesada, V.3
  • 16
    • 84874102335 scopus 로고    scopus 로고
    • Evolution and impact of subclonal mutations in chronic lymphocytic leukemia
    • Landau DA, Carter SL, Stojanov P, et al. Evolution and impact of subclonal mutations in chronic lymphocytic leukemia. Cell. 2013;152(4): 714-726.
    • (2013) Cell. , vol.152 , Issue.4 , pp. 714-726
    • Landau, D.A.1    Carter, S.L.2    Stojanov, P.3
  • 17
    • 84906908742 scopus 로고    scopus 로고
    • Acquired initiating mutations in early hematopoietic cells of CLL patients
    • Damm F, Mylonas E, Cosson A, et al. Acquired initiating mutations in early hematopoietic cells of CLL patients. Cancer Discov. 2014;4(9): 1088-1101.
    • (2014) Cancer Discov. , vol.4 , Issue.9 , pp. 1088-1101
    • Damm, F.1    Mylonas, E.2    Cosson, A.3
  • 18
    • 84893699492 scopus 로고    scopus 로고
    • Transcriptome characterization by RNA sequencing identifies a major molecular and clinical subdivision in chronic lymphocytic leukemia
    • Ferreira PG, Jares P, Rico D, et al. Transcriptome characterization by RNA sequencing identifies a major molecular and clinical subdivision in chronic lymphocytic leukemia. Genome Res. 2014;24(2):212-226.
    • (2014) Genome Res. , vol.24 , Issue.2 , pp. 212-226
    • Ferreira, P.G.1    Jares, P.2    Rico, D.3
  • 19
    • 84868198427 scopus 로고    scopus 로고
    • Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia
    • Kulis M, Heath S, Bibikova M, et al. Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia. Nat Genet. 2012;44(11):1236-1242.
    • (2012) Nat Genet. , vol.44 , Issue.11 , pp. 1236-1242
    • Kulis, M.1    Heath, S.2    Bibikova, M.3
  • 21
    • 61349151633 scopus 로고    scopus 로고
    • Role of chromodomain helicase DNA-binding protein 2 in DNA damage response signaling and tumorigenesis
    • Nagarajan P, Onami TM, Rajagopalan S, Kania S, Donnell R, Venkatachalam S. Role of chromodomain helicase DNA-binding protein 2 in DNA damage response signaling and tumorigenesis. Oncogene. 2009;28(8): 1053-1062.
    • (2009) Oncogene. , vol.28 , Issue.8 , pp. 1053-1062
    • Nagarajan, P.1    Onami, T.M.2    Rajagopalan, S.3    Kania, S.4    Donnell, R.5    Venkatachalam, S.6
  • 22
    • 84892836847 scopus 로고    scopus 로고
    • Monoclonal B cell lymphocytosis and "in situ" lymphoma
    • Karube K, Scarfo L, Campo E, Ghia P. Monoclonal B cell lymphocytosis and "in situ" lymphoma. Semin Cancer Biol. 2014;24:3-14.
    • (2014) Semin Cancer Biol. , vol.24 , pp. 3-14
    • Karube, K.1    Scarfo, L.2    Campo, E.3    Ghia, P.4
  • 23
    • 77951115122 scopus 로고    scopus 로고
    • International network of cancer genome projects [published correction appears in Nature. 2010;465 (7300 966]
    • International Cancer Genome Consortium
    • Hudson TJ, Anderson W, Artez A, et al; International Cancer Genome Consortium. International network of cancer genome projects [published correction appears in Nature. 2010;465 (7300):966]. Nature. 2010;464(7291):993-998.
    • (2010) Nature. , vol.464 , Issue.7291 , pp. 993-998
    • Hudson, T.J.1    Anderson, W.2    Artez, A.3
  • 24
    • 0027418205 scopus 로고
    • Measurement of co-localization of objects in dual-colour confocal image
    • Manders EMM, Verbeek FJ, Aten JA. Measurement of co-localization of objects in dual-colour confocal image. J Microsc Oxford. 1993;169(3):375-382.
    • (1993) J Microsc Oxford. , vol.169 , Issue.3 , pp. 375-382
    • Manders, E.M.M.1    Verbeek, F.J.2    Aten, J.A.3
  • 25
    • 27344435774 scopus 로고    scopus 로고
    • Gene set enrichment analysis: A knowledgebased approach for interpreting genome-wide expression profiles
    • Subramanian A, Tamayo P, Mootha VK, et al. Gene set enrichment analysis: A knowledgebased approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA. 2005;102(43):15545-15550.
    • (2005) Proc Natl Acad Sci USA. , vol.102 , Issue.43 , pp. 15545-15550
    • Subramanian, A.1    Tamayo, P.2    Mootha, V.K.3
  • 27
    • 79953715693 scopus 로고    scopus 로고
    • Improving the assessment of the outcome of nonsynonymous SNVs with a consensus deleteriousness score, Condel
    • González-Pérez A, López-Bigas N. Improving the assessment of the outcome of nonsynonymous SNVs with a consensus deleteriousness score, Condel. Am J Hum Genet. 2011;88(4):440-449.
    • (2011) Am J Hum Genet. , vol.88 , Issue.4 , pp. 440-449
    • González-Pérez, A.1    López-Bigas, N.2
  • 28
    • 78651330430 scopus 로고    scopus 로고
    • COSMIC: Mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer
    • Forbes SA, Bindal N, Bamford S, et al. COSMIC: Mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer. Nucleic Acids Res. 2011;39(suppl 1):D945-D950.
    • (2011) Nucleic Acids Res. , vol.39 , pp. 945-950
    • Forbes, S.A.1    Bindal, N.2    Bamford, S.3
  • 29
    • 34147158728 scopus 로고    scopus 로고
    • The Chd family of chromatin remodelers
    • Marfella CG, Imbalzano AN. The Chd family of chromatin remodelers. Mutat Res. 2007;618(1-2): 30-40.
    • (2007) Mutat Res. , vol.618 , Issue.1-2 , pp. 30-40
    • Marfella, C.G.1    Imbalzano, A.N.2
  • 30
    • 84855165141 scopus 로고    scopus 로고
    • CHD chromatin remodelers and the transcription cycle
    • Murawska M, Brehm A. CHD chromatin remodelers and the transcription cycle. Transcription. 2011;2(6):244-253.
    • (2011) Transcription. , vol.2 , Issue.6 , pp. 244-253
    • Murawska, M.1    Brehm, A.2
  • 31
    • 36249027156 scopus 로고    scopus 로고
    • Recognition of trimethylated histone H3 lysine 4 facilitates the recruitment of transcription postinitiation factors and pre-mRNA splicing
    • Sims RJ III, Millhouse S, Chen CF, et al. Recognition of trimethylated histone H3 lysine 4 facilitates the recruitment of transcription postinitiation factors and pre-mRNA splicing. Mol Cell. 2007;28(4):665-676.
    • (2007) Mol Cell. , vol.28 , Issue.4 , pp. 665-676
    • Sims, R.J.1    Millhouse, S.2    Chen, C.F.3
  • 32
    • 84880064679 scopus 로고    scopus 로고
    • Interplay between chromatin state, regulator binding, and regulatory motifs in six human cell types
    • Ernst J, Kellis M. Interplay between chromatin state, regulator binding, and regulatory motifs in six human cell types. Genome Res. 2013;23(7): 1142-1154.
    • (2013) Genome Res. , vol.23 , Issue.7 , pp. 1142-1154
    • Ernst, J.1    Kellis, M.2
  • 34
    • 29644433964 scopus 로고    scopus 로고
    • Human but not yeast CHD1 binds directly and selectively to histone H3 methylated at lysine 4 via its tandem chromodomains
    • Sims RJ III, Chen CF, Santos-Rosa H, Kouzarides T, Patel SS, Reinberg D. Human but not yeast CHD1 binds directly and selectively to histone H3 methylated at lysine 4 via its tandem chromodomains. J Biol Chem. 2005;280(51): 41789-41792.
    • (2005) J Biol Chem. , vol.280 , Issue.51 , pp. 41789-41792
    • Sims, R.J.1    Chen, C.F.2    Santos-Rosa, H.3    Kouzarides, T.4    Patel, S.S.5    Reinberg, D.6
  • 35
    • 84863812324 scopus 로고    scopus 로고
    • Chd2 interacts with H3.3 to determine myogenic cell fate
    • Harada A, Okada S, Konno D, et al. Chd2 interacts with H3.3 to determine myogenic cell fate. EMBO J. 2012;31(13):2994-3007.
    • (2012) EMBO J. , vol.31 , Issue.13 , pp. 2994-3007
    • Harada, A.1    Okada, S.2    Konno, D.3
  • 36
    • 0032961892 scopus 로고    scopus 로고
    • CHD1 interacts with SSRP1 and depends on both its chromodomain and its ATPase/helicase-like domain for proper association with chromatin
    • Kelley DE, Stokes DG, Perry RP. CHD1 interacts with SSRP1 and depends on both its chromodomain and its ATPase/helicase-like domain for proper association with chromatin. Chromosoma. 1999;108(1):10-25.
    • (1999) Chromosoma. , vol.108 , Issue.1 , pp. 10-25
    • De, K.1    Stokes, D.G.2    Perry, R.P.3
  • 37
    • 0041669439 scopus 로고    scopus 로고
    • Nuclear speckles: A model for nuclear organelles
    • Lamond AI, Spector DL. Nuclear speckles: A model for nuclear organelles. Nat Rev Mol Cell Biol. 2003;4(8):605-612.
    • (2003) Nat Rev Mol Cell Biol. , vol.4 , Issue.8 , pp. 605-612
    • Lamond, A.I.1    Spector, D.L.2
  • 38
    • 84897490051 scopus 로고    scopus 로고
    • How will B-cell-receptortargeted therapies change future CLL therapy?
    • Jones JA, Byrd JC. How will B-cell-receptortargeted therapies change future CLL therapy? Blood. 2014;123(10):1455-1460.
    • (2014) Blood. , vol.123 , Issue.10 , pp. 1455-1460
    • Jones, J.A.1    Byrd, J.C.2
  • 39
    • 84879684377 scopus 로고    scopus 로고
    • Targeted resequencing in epileptic encephalopathies identifies De novo mutations in CHD2 and SYNGAP1
    • Carvill GL, Heavin SB, Yendle SC, et al. Targeted resequencing in epileptic encephalopathies identifies De novo mutations in CHD2 and SYNGAP1. Nat Genet. 2013;45(7):825-830.
    • (2013) Nat Genet. , vol.45 , Issue.7 , pp. 825-830
    • Carvill, G.L.1    Heavin, S.B.2    Yendle, S.C.3
  • 40
    • 84890151248 scopus 로고    scopus 로고
    • De novo lossof-function mutations in CHD2 cause a feversensitive myoclonic epileptic encephalopathy sharing features with Dravet syndrome
    • EuroEPINOMICS RES Consortium
    • Suls A, Jaehn JA, Kecskés A, et al; EuroEPINOMICS RES Consortium. De novo lossof-function mutations in CHD2 cause a feversensitive myoclonic epileptic encephalopathy sharing features with Dravet syndrome. Am J Hum Genet. 2013;93(5):967-975.
    • (2013) Am J Hum Genet. , vol.93 , Issue.5 , pp. 967-975
    • Suls, A.1    Jaehn, J.A.2    Kecskés, A.3
  • 41
    • 73649116987 scopus 로고    scopus 로고
    • The DLEU2/MIR-15a/16-1 cluster controls B cell proliferation and its deletion leads to chronic lymphocytic leukemia
    • Klein U, Lia M, Crespo M, et al. The DLEU2/miR-15a/16-1 cluster controls B cell proliferation and its deletion leads to chronic lymphocytic leukemia. Cancer Cell. 2010;17(1):28-40.
    • (2010) Cancer Cell. , vol.17 , Issue.1 , pp. 28-40
    • Klein, U.1    Lia, M.2    Crespo, M.3
  • 44
    • 84877747485 scopus 로고    scopus 로고
    • CHD1 is a 5q21 tumor suppressor required for ERG rearrangement in prostate cancer
    • Burkhardt L, Fuchs S, Krohn A, et al. CHD1 is a 5q21 tumor suppressor required for ERG rearrangement in prostate cancer. Cancer Res. 2013;73(9):2795-2805.
    • (2013) Cancer Res. , vol.73 , Issue.9 , pp. 2795-2805
    • Burkhardt, L.1    Fuchs, S.2    Krohn, A.3
  • 46
    • 84911494217 scopus 로고    scopus 로고
    • Principles of Regulatory Information Conservation between Mouse and Human
    • Mouse ENCODE Consortium
    • Cheng Y, Ma Z, Kim BH, et al; Mouse ENCODE Consortium. Principles of regulatory information conservation between mouse and human. Nature. 2014;515(7527):371-375.
    • (2014) Nature , vol.515 , Issue.7527 , pp. 371-375
    • Cheng, Y.1    Ma, Z.2    Kim, B.H.3
  • 47
    • 84920522426 scopus 로고    scopus 로고
    • Human CHD2 is a chromatin assembly ATPase regulated by its chromo-and DNA-binding domains
    • Liu JC, Ferreira CG, Yusufzai T. Human CHD2 is a chromatin assembly ATPase regulated by its chromo-and DNA-binding domains. J Biol Chem. 2015;290(1):25-34.
    • (2015) J Biol Chem. , vol.290 , Issue.1 , pp. 25-34
    • Liu, J.C.1    Ferreira, C.G.2    Yusufzai, T.3
  • 49
    • 84901712964 scopus 로고    scopus 로고
    • Idelalisib, an inhibitor of phosphatidylinositol 3-kinase p110d, for relapsed/refractory chronic lymphocytic leukemia
    • Brown JR, Byrd JC, Coutre SE, et al. Idelalisib, an inhibitor of phosphatidylinositol 3-kinase p110d, for relapsed/refractory chronic lymphocytic leukemia. Blood. 2014;123(22):3390-3397.
    • (2014) Blood. , vol.123 , Issue.22 , pp. 3390-3397
    • Brown, J.R.1    Byrd, J.C.2    Coutre, S.E.3
  • 50
    • 84899638389 scopus 로고    scopus 로고
    • Prognostic and predictive factors in patients with chronic lymphocytic leukemia relevant in the era of novel treatment approaches?
    • Mertens D, Stilgenbauer S. Prognostic and predictive factors in patients with chronic lymphocytic leukemia: Relevant in the era of novel treatment approaches? J Clin Oncol. 2014;32(9): 869-872.
    • (2014) J Clin Oncol. , vol.32 , Issue.9 , pp. 869-872
    • Mertens, D.1    Stilgenbauer, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.