-
1
-
-
84867154468
-
Molecular pathogenesis of chronic lymphocytic leukemia
-
Gaidano G, Fòa R, Dalla-Favera R. Molecular pathogenesis of chronic lymphocytic leukemia. J Clin Invest. 2012;122(10):3432-3438.
-
(2012)
J Clin Invest.
, vol.122
, Issue.10
, pp. 3432-3438
-
-
Gaidano, G.1
Fòa, R.2
Dalla-Favera, R.3
-
3
-
-
72949093335
-
From pathogenesis to treatment of chronic lymphocytic leukaemia
-
Zenz T, Mertens D, Küppers R, Döhner H, Stilgenbauer S. From pathogenesis to treatment of chronic lymphocytic leukaemia. Nat Rev Cancer. 2010;10(1):37-50.
-
(2010)
Nat Rev Cancer.
, vol.10
, Issue.1
, pp. 37-50
-
-
Zenz, T.1
Mertens, D.2
Küppers, R.3
Döhner, H.4
Stilgenbauer, S.5
-
4
-
-
0033567907
-
Unmutated Ig V(H)genes are associated with a more aggressive form of chronic lymphocytic leukemia
-
Hamblin TJ, Davis Z, Gardiner A, Oscier DG, Stevenson FK. Unmutated Ig V(H) genes are associated with a more aggressive form of chronic lymphocytic leukemia. Blood. 1999;94(6): 1848-1854.
-
(1999)
Blood.
, vol.94
, Issue.6
, pp. 1848-1854
-
-
Hamblin, T.J.1
Davis, Z.2
Gardiner, A.3
Oscier, D.G.4
Stevenson, F.K.5
-
5
-
-
0033567968
-
Ig v gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia
-
Damle RN, Wasil T, Fais F, et al. Ig V gene mutation status and CD38 expression as novel prognostic indicators in chronic lymphocytic leukemia. Blood. 1999;94(6):1840-1847.
-
(1999)
Blood.
, vol.94
, Issue.6
, pp. 1840-1847
-
-
Damle, R.N.1
Wasil, T.2
Fais, F.3
-
6
-
-
0037406968
-
ZAP-70 expression as a surrogate for immunoglobulinvariable-region mutations in chronic lymphocytic leukemia
-
Crespo M, Bosch F, Villamor N, et al. ZAP-70 expression as a surrogate for immunoglobulinvariable-region mutations in chronic lymphocytic leukemia. N Engl J Med. 2003;348(18): 1764-1775.
-
(2003)
N Engl J Med.
, vol.348
, Issue.18
, pp. 1764-1775
-
-
Crespo, M.1
Bosch, F.2
Villamor, N.3
-
7
-
-
0034727833
-
Genomic aberrations and survival in chronic lymphocytic leukemia
-
Döhner H, Stilgenbauer S, Benner A, et al. Genomic aberrations and survival in chronic lymphocytic leukemia. N Engl J Med. 2000; 343(26):1910-1916.
-
(2000)
N Engl J Med.
, vol.343
, Issue.26
, pp. 1910-1916
-
-
Döhner, H.1
Stilgenbauer, S.2
Benner, A.3
-
8
-
-
38349084386
-
Relevance of CD49d protein expression as overall survival and progressive disease prognosticator in chronic lymphocytic leukemia
-
Gattei V, Bulian P, Del Principe MI, et al. Relevance of CD49d protein expression as overall survival and progressive disease prognosticator in chronic lymphocytic leukemia. Blood. 2008; 111(2):865-873.
-
(2008)
Blood.
, vol.111
, Issue.2
, pp. 865-873
-
-
Gattei, V.1
Bulian, P.2
Del Principe, M.I.3
-
9
-
-
79960036578
-
Wholegenome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia
-
Puente XS, Pinyol M, Quesada V, et al. Wholegenome sequencing identifies recurrent mutations in chronic lymphocytic leukaemia. Nature. 2011; 475(7354):101-105.
-
(2011)
Nature.
, vol.475
, Issue.7354
, pp. 101-105
-
-
Puente, X.S.1
Pinyol, M.2
Quesada, V.3
-
10
-
-
84555171449
-
Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia
-
Quesada V, Conde L, Villamor N, et al. Exome sequencing identifies recurrent mutations of the splicing factor SF3B1 gene in chronic lymphocytic leukemia. Nat Genet. 2012;44(1):47-52.
-
(2012)
Nat Genet.
, vol.44
, Issue.1
, pp. 47-52
-
-
Quesada, V.1
Conde, L.2
Villamor, N.3
-
11
-
-
79960353160
-
Analysis of the chronic lymphocytic leukemia coding genome: Role of NOTCH1 mutational activation
-
Fabbri G, Rasi S, Rossi D, et al. Analysis of the chronic lymphocytic leukemia coding genome: Role of NOTCH1 mutational activation. J Exp Med. 2011;208(7):1389-1401.
-
(2011)
J Exp Med.
, vol.208
, Issue.7
, pp. 1389-1401
-
-
Fabbri, G.1
Rasi, S.2
Rossi, D.3
-
12
-
-
84862854953
-
Chronic lymphocytic leukemia with SF3B1 mutation
-
Quesada V, Ramsay AJ, Lopez-Otin C. Chronic lymphocytic leukemia with SF3B1 mutation. N Engl J Med. 2012;366(26):2530.
-
(2012)
N Engl J Med.
, vol.366
, Issue.26
, pp. 2530
-
-
Quesada, V.1
Ramsay, A.J.2
Lopez-Otin, C.3
-
13
-
-
84855370035
-
SF3B1 and other novel cancer genes in chronic lymphocytic leukemia
-
Wang L, Lawrence MS, Wan Y, et al. SF3B1 and other novel cancer genes in chronic lymphocytic leukemia. N Engl J Med. 2011;365(26): 2497-2506.
-
(2011)
N Engl J Med.
, vol.365
, Issue.26
, pp. 2497-2506
-
-
Wang, L.1
Lawrence, M.S.2
Wan, Y.3
-
14
-
-
84878551940
-
POT1 mutations cause telomere dysfunction in chronic lymphocytic leukemia
-
Ramsay AJ, Quesada V, Foronda M, et al. POT1 mutations cause telomere dysfunction in chronic lymphocytic leukemia. Nat Genet. 2013;45(5): 526-530.
-
(2013)
Nat Genet.
, vol.45
, Issue.5
, pp. 526-530
-
-
Ramsay, A.J.1
Quesada, V.2
Foronda, M.3
-
15
-
-
84877894013
-
Functional analysis of sucrase-isomaltase mutations from chronic lymphocytic leukemia patients
-
Rodŕ?guez D, Ramsay AJ, Quesada V, et al. Functional analysis of sucrase-isomaltase mutations from chronic lymphocytic leukemia patients. Hum Mol Genet. 2013;22(11): 2273-2282.
-
(2013)
Hum Mol Genet.
, vol.22
, Issue.11
, pp. 2273-2282
-
-
Rodŕguez, D.1
Ramsay, A.J.2
Quesada, V.3
-
16
-
-
84874102335
-
Evolution and impact of subclonal mutations in chronic lymphocytic leukemia
-
Landau DA, Carter SL, Stojanov P, et al. Evolution and impact of subclonal mutations in chronic lymphocytic leukemia. Cell. 2013;152(4): 714-726.
-
(2013)
Cell.
, vol.152
, Issue.4
, pp. 714-726
-
-
Landau, D.A.1
Carter, S.L.2
Stojanov, P.3
-
17
-
-
84906908742
-
Acquired initiating mutations in early hematopoietic cells of CLL patients
-
Damm F, Mylonas E, Cosson A, et al. Acquired initiating mutations in early hematopoietic cells of CLL patients. Cancer Discov. 2014;4(9): 1088-1101.
-
(2014)
Cancer Discov.
, vol.4
, Issue.9
, pp. 1088-1101
-
-
Damm, F.1
Mylonas, E.2
Cosson, A.3
-
18
-
-
84893699492
-
Transcriptome characterization by RNA sequencing identifies a major molecular and clinical subdivision in chronic lymphocytic leukemia
-
Ferreira PG, Jares P, Rico D, et al. Transcriptome characterization by RNA sequencing identifies a major molecular and clinical subdivision in chronic lymphocytic leukemia. Genome Res. 2014;24(2):212-226.
-
(2014)
Genome Res.
, vol.24
, Issue.2
, pp. 212-226
-
-
Ferreira, P.G.1
Jares, P.2
Rico, D.3
-
19
-
-
84868198427
-
Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia
-
Kulis M, Heath S, Bibikova M, et al. Epigenomic analysis detects widespread gene-body DNA hypomethylation in chronic lymphocytic leukemia. Nat Genet. 2012;44(11):1236-1242.
-
(2012)
Nat Genet.
, vol.44
, Issue.11
, pp. 1236-1242
-
-
Kulis, M.1
Heath, S.2
Bibikova, M.3
-
20
-
-
33748271305
-
Mutation of the SNF2 family member Chd2 affects mouse development and survival
-
Marfella CG, Ohkawa Y, Coles AH, Garlick DS, Jones SN, Imbalzano AN. Mutation of the SNF2 family member Chd2 affects mouse development and survival. J Cell Physiol. 2006;209(1):162-171.
-
(2006)
J Cell Physiol.
, vol.209
, Issue.1
, pp. 162-171
-
-
Marfella, C.G.1
Ohkawa, Y.2
Coles, A.H.3
Garlick, D.S.4
Jones, S.N.5
Imbalzano, A.N.6
-
21
-
-
61349151633
-
Role of chromodomain helicase DNA-binding protein 2 in DNA damage response signaling and tumorigenesis
-
Nagarajan P, Onami TM, Rajagopalan S, Kania S, Donnell R, Venkatachalam S. Role of chromodomain helicase DNA-binding protein 2 in DNA damage response signaling and tumorigenesis. Oncogene. 2009;28(8): 1053-1062.
-
(2009)
Oncogene.
, vol.28
, Issue.8
, pp. 1053-1062
-
-
Nagarajan, P.1
Onami, T.M.2
Rajagopalan, S.3
Kania, S.4
Donnell, R.5
Venkatachalam, S.6
-
23
-
-
77951115122
-
International network of cancer genome projects [published correction appears in Nature. 2010;465 (7300 966]
-
International Cancer Genome Consortium
-
Hudson TJ, Anderson W, Artez A, et al; International Cancer Genome Consortium. International network of cancer genome projects [published correction appears in Nature. 2010;465 (7300):966]. Nature. 2010;464(7291):993-998.
-
(2010)
Nature.
, vol.464
, Issue.7291
, pp. 993-998
-
-
Hudson, T.J.1
Anderson, W.2
Artez, A.3
-
24
-
-
0027418205
-
Measurement of co-localization of objects in dual-colour confocal image
-
Manders EMM, Verbeek FJ, Aten JA. Measurement of co-localization of objects in dual-colour confocal image. J Microsc Oxford. 1993;169(3):375-382.
-
(1993)
J Microsc Oxford.
, vol.169
, Issue.3
, pp. 375-382
-
-
Manders, E.M.M.1
Verbeek, F.J.2
Aten, J.A.3
-
25
-
-
27344435774
-
Gene set enrichment analysis: A knowledgebased approach for interpreting genome-wide expression profiles
-
Subramanian A, Tamayo P, Mootha VK, et al. Gene set enrichment analysis: A knowledgebased approach for interpreting genome-wide expression profiles. Proc Natl Acad Sci USA. 2005;102(43):15545-15550.
-
(2005)
Proc Natl Acad Sci USA.
, vol.102
, Issue.43
, pp. 15545-15550
-
-
Subramanian, A.1
Tamayo, P.2
Mootha, V.K.3
-
26
-
-
79958135926
-
Molecular signatures database (MSigDB) 3.0
-
Liberzon A, Subramanian A, Pinchback R, Thorvaldsdóttir H, Tamayo P, Mesirov JP. Molecular signatures database (MSigDB) 3.0. Bioinformatics. 2011;27(12):1739-1740.
-
(2011)
Bioinformatics.
, vol.27
, Issue.12
, pp. 1739-1740
-
-
Liberzon, A.1
Subramanian, A.2
Pinchback, R.3
Thorvaldsdóttir, H.4
Tamayo, P.5
Mesirov, J.P.6
-
27
-
-
79953715693
-
Improving the assessment of the outcome of nonsynonymous SNVs with a consensus deleteriousness score, Condel
-
González-Pérez A, López-Bigas N. Improving the assessment of the outcome of nonsynonymous SNVs with a consensus deleteriousness score, Condel. Am J Hum Genet. 2011;88(4):440-449.
-
(2011)
Am J Hum Genet.
, vol.88
, Issue.4
, pp. 440-449
-
-
González-Pérez, A.1
López-Bigas, N.2
-
28
-
-
78651330430
-
COSMIC: Mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer
-
Forbes SA, Bindal N, Bamford S, et al. COSMIC: Mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer. Nucleic Acids Res. 2011;39(suppl 1):D945-D950.
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. 945-950
-
-
Forbes, S.A.1
Bindal, N.2
Bamford, S.3
-
29
-
-
34147158728
-
The Chd family of chromatin remodelers
-
Marfella CG, Imbalzano AN. The Chd family of chromatin remodelers. Mutat Res. 2007;618(1-2): 30-40.
-
(2007)
Mutat Res.
, vol.618
, Issue.1-2
, pp. 30-40
-
-
Marfella, C.G.1
Imbalzano, A.N.2
-
30
-
-
84855165141
-
CHD chromatin remodelers and the transcription cycle
-
Murawska M, Brehm A. CHD chromatin remodelers and the transcription cycle. Transcription. 2011;2(6):244-253.
-
(2011)
Transcription.
, vol.2
, Issue.6
, pp. 244-253
-
-
Murawska, M.1
Brehm, A.2
-
31
-
-
36249027156
-
Recognition of trimethylated histone H3 lysine 4 facilitates the recruitment of transcription postinitiation factors and pre-mRNA splicing
-
Sims RJ III, Millhouse S, Chen CF, et al. Recognition of trimethylated histone H3 lysine 4 facilitates the recruitment of transcription postinitiation factors and pre-mRNA splicing. Mol Cell. 2007;28(4):665-676.
-
(2007)
Mol Cell.
, vol.28
, Issue.4
, pp. 665-676
-
-
Sims, R.J.1
Millhouse, S.2
Chen, C.F.3
-
32
-
-
84880064679
-
Interplay between chromatin state, regulator binding, and regulatory motifs in six human cell types
-
Ernst J, Kellis M. Interplay between chromatin state, regulator binding, and regulatory motifs in six human cell types. Genome Res. 2013;23(7): 1142-1154.
-
(2013)
Genome Res.
, vol.23
, Issue.7
, pp. 1142-1154
-
-
Ernst, J.1
Kellis, M.2
-
33
-
-
34247576687
-
Molecular implications of evolutionary differences in CHD double chromodomains
-
Flanagan JF, Blus BJ, Kim D, Clines KL, Rastinejad F, Khorasanizadeh S. Molecular implications of evolutionary differences in CHD double chromodomains. J Mol Biol. 2007;369(2): 334-342.
-
(2007)
J Mol Biol.
, vol.369
, Issue.2
, pp. 334-342
-
-
Flanagan, J.F.1
Blus, B.J.2
Kim, D.3
Clines, K.L.4
Rastinejad, F.5
Khorasanizadeh, S.6
-
34
-
-
29644433964
-
Human but not yeast CHD1 binds directly and selectively to histone H3 methylated at lysine 4 via its tandem chromodomains
-
Sims RJ III, Chen CF, Santos-Rosa H, Kouzarides T, Patel SS, Reinberg D. Human but not yeast CHD1 binds directly and selectively to histone H3 methylated at lysine 4 via its tandem chromodomains. J Biol Chem. 2005;280(51): 41789-41792.
-
(2005)
J Biol Chem.
, vol.280
, Issue.51
, pp. 41789-41792
-
-
Sims, R.J.1
Chen, C.F.2
Santos-Rosa, H.3
Kouzarides, T.4
Patel, S.S.5
Reinberg, D.6
-
35
-
-
84863812324
-
Chd2 interacts with H3.3 to determine myogenic cell fate
-
Harada A, Okada S, Konno D, et al. Chd2 interacts with H3.3 to determine myogenic cell fate. EMBO J. 2012;31(13):2994-3007.
-
(2012)
EMBO J.
, vol.31
, Issue.13
, pp. 2994-3007
-
-
Harada, A.1
Okada, S.2
Konno, D.3
-
36
-
-
0032961892
-
CHD1 interacts with SSRP1 and depends on both its chromodomain and its ATPase/helicase-like domain for proper association with chromatin
-
Kelley DE, Stokes DG, Perry RP. CHD1 interacts with SSRP1 and depends on both its chromodomain and its ATPase/helicase-like domain for proper association with chromatin. Chromosoma. 1999;108(1):10-25.
-
(1999)
Chromosoma.
, vol.108
, Issue.1
, pp. 10-25
-
-
De, K.1
Stokes, D.G.2
Perry, R.P.3
-
37
-
-
0041669439
-
Nuclear speckles: A model for nuclear organelles
-
Lamond AI, Spector DL. Nuclear speckles: A model for nuclear organelles. Nat Rev Mol Cell Biol. 2003;4(8):605-612.
-
(2003)
Nat Rev Mol Cell Biol.
, vol.4
, Issue.8
, pp. 605-612
-
-
Lamond, A.I.1
Spector, D.L.2
-
38
-
-
84897490051
-
How will B-cell-receptortargeted therapies change future CLL therapy?
-
Jones JA, Byrd JC. How will B-cell-receptortargeted therapies change future CLL therapy? Blood. 2014;123(10):1455-1460.
-
(2014)
Blood.
, vol.123
, Issue.10
, pp. 1455-1460
-
-
Jones, J.A.1
Byrd, J.C.2
-
39
-
-
84879684377
-
Targeted resequencing in epileptic encephalopathies identifies De novo mutations in CHD2 and SYNGAP1
-
Carvill GL, Heavin SB, Yendle SC, et al. Targeted resequencing in epileptic encephalopathies identifies De novo mutations in CHD2 and SYNGAP1. Nat Genet. 2013;45(7):825-830.
-
(2013)
Nat Genet.
, vol.45
, Issue.7
, pp. 825-830
-
-
Carvill, G.L.1
Heavin, S.B.2
Yendle, S.C.3
-
40
-
-
84890151248
-
De novo lossof-function mutations in CHD2 cause a feversensitive myoclonic epileptic encephalopathy sharing features with Dravet syndrome
-
EuroEPINOMICS RES Consortium
-
Suls A, Jaehn JA, Kecskés A, et al; EuroEPINOMICS RES Consortium. De novo lossof-function mutations in CHD2 cause a feversensitive myoclonic epileptic encephalopathy sharing features with Dravet syndrome. Am J Hum Genet. 2013;93(5):967-975.
-
(2013)
Am J Hum Genet.
, vol.93
, Issue.5
, pp. 967-975
-
-
Suls, A.1
Jaehn, J.A.2
Kecskés, A.3
-
41
-
-
73649116987
-
The DLEU2/MIR-15a/16-1 cluster controls B cell proliferation and its deletion leads to chronic lymphocytic leukemia
-
Klein U, Lia M, Crespo M, et al. The DLEU2/miR-15a/16-1 cluster controls B cell proliferation and its deletion leads to chronic lymphocytic leukemia. Cancer Cell. 2010;17(1):28-40.
-
(2010)
Cancer Cell.
, vol.17
, Issue.1
, pp. 28-40
-
-
Klein, U.1
Lia, M.2
Crespo, M.3
-
42
-
-
84875490185
-
Cancer genome landscapes
-
Vogelstein B, Papadopoulos N, Velculescu VE, Zhou S, Diaz LA Jr, Kinzler KW. Cancer genome landscapes. Science. 2013;339(6127): 1546-1558.
-
(2013)
Science.
, vol.339
, Issue.6127
, pp. 1546-1558
-
-
Vogelstein, B.1
Papadopoulos, N.2
Velculescu, V.E.3
Zhou, S.4
Diaz, L.A.5
Kinzler, K.W.6
-
43
-
-
84877106592
-
The genomic landscape of chronic lymphocytic leukemia: Clinical implications
-
Quesada V, Ramsay AJ, Rodŕ?guez D, Puente XS, Campo E, López-Otń C. The genomic landscape of chronic lymphocytic leukemia: Clinical implications. BMC Med. 2013;11:124.
-
(2013)
BMC Med.
, vol.11
, pp. 124
-
-
Quesada, V.1
Ramsay, A.J.2
Rodŕguez, D.3
Puente, X.S.4
Campo, E.5
López-Otń, C.6
-
44
-
-
84877747485
-
CHD1 is a 5q21 tumor suppressor required for ERG rearrangement in prostate cancer
-
Burkhardt L, Fuchs S, Krohn A, et al. CHD1 is a 5q21 tumor suppressor required for ERG rearrangement in prostate cancer. Cancer Res. 2013;73(9):2795-2805.
-
(2013)
Cancer Res.
, vol.73
, Issue.9
, pp. 2795-2805
-
-
Burkhardt, L.1
Fuchs, S.2
Krohn, A.3
-
45
-
-
84893872436
-
Role of CHD5 in human cancers: 10 years later
-
Kolla V, Zhuang T, Higashi M, Naraparaju K, Brodeur GM. Role of CHD5 in human cancers: 10 years later. Cancer Res. 2014;74(3):652-658.
-
(2014)
Cancer Res.
, vol.74
, Issue.3
, pp. 652-658
-
-
Kolla, V.1
Zhuang, T.2
Higashi, M.3
Naraparaju, K.4
Brodeur, G.M.5
-
46
-
-
84911494217
-
Principles of Regulatory Information Conservation between Mouse and Human
-
Mouse ENCODE Consortium
-
Cheng Y, Ma Z, Kim BH, et al; Mouse ENCODE Consortium. Principles of regulatory information conservation between mouse and human. Nature. 2014;515(7527):371-375.
-
(2014)
Nature
, vol.515
, Issue.7527
, pp. 371-375
-
-
Cheng, Y.1
Ma, Z.2
Kim, B.H.3
-
47
-
-
84920522426
-
Human CHD2 is a chromatin assembly ATPase regulated by its chromo-and DNA-binding domains
-
Liu JC, Ferreira CG, Yusufzai T. Human CHD2 is a chromatin assembly ATPase regulated by its chromo-and DNA-binding domains. J Biol Chem. 2015;290(1):25-34.
-
(2015)
J Biol Chem.
, vol.290
, Issue.1
, pp. 25-34
-
-
Liu, J.C.1
Ferreira, C.G.2
Yusufzai, T.3
-
48
-
-
0344629441
-
Global control of histone modification by the anaphase-promoting complex
-
Ramaswamy V, Williams JS, Robinson KM, Sopko RL, Schultz MC. Global control of histone modification by the anaphase-promoting complex. Mol Cell Biol. 2003;23(24):9136-9149.
-
(2003)
Mol Cell Biol.
, vol.23
, Issue.24
, pp. 9136-9149
-
-
Ramaswamy, V.1
Williams, J.S.2
Robinson, K.M.3
Sopko, R.L.4
Schultz, M.C.5
-
49
-
-
84901712964
-
Idelalisib, an inhibitor of phosphatidylinositol 3-kinase p110d, for relapsed/refractory chronic lymphocytic leukemia
-
Brown JR, Byrd JC, Coutre SE, et al. Idelalisib, an inhibitor of phosphatidylinositol 3-kinase p110d, for relapsed/refractory chronic lymphocytic leukemia. Blood. 2014;123(22):3390-3397.
-
(2014)
Blood.
, vol.123
, Issue.22
, pp. 3390-3397
-
-
Brown, J.R.1
Byrd, J.C.2
Coutre, S.E.3
-
50
-
-
84899638389
-
Prognostic and predictive factors in patients with chronic lymphocytic leukemia relevant in the era of novel treatment approaches?
-
Mertens D, Stilgenbauer S. Prognostic and predictive factors in patients with chronic lymphocytic leukemia: Relevant in the era of novel treatment approaches? J Clin Oncol. 2014;32(9): 869-872.
-
(2014)
J Clin Oncol.
, vol.32
, Issue.9
, pp. 869-872
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-
Mertens, D.1
Stilgenbauer, S.2
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