메뉴 건너뛰기




Volumn 6, Issue 18, 2015, Pages 16321-16340

Inhibition of TRPM7 by carvacrol suppresses glioblastoma cell proliferation, migration and invasion

Author keywords

Carvacrol; Cell viability; Glioblastoma; Invasion; Migration; TRPM7

Indexed keywords

CARVACROL; CASPASE 3; COFILIN; GELATINASE A; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN KINASE B; TRANSIENT RECEPTOR POTENTIAL CHANNEL M7; ACTIN DEPOLYMERIZING FACTOR; ANTINEOPLASTIC AGENT; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; MMP2 PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE; SMALL INTERFERING RNA; TERPENE; TRANSIENT RECEPTOR POTENTIAL CHANNEL M; TRPM7 PROTEIN, HUMAN;

EID: 84937888059     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.3872     Document Type: Article
Times cited : (120)

References (74)
  • 4
    • 84907163549 scopus 로고    scopus 로고
    • Editorial: emerging concepts and therapeutics strategies for the treatment of brain tumors
    • Chen J and Yakisich JS. Editorial: emerging concepts and therapeutics strategies for the treatment of brain tumors. Anti-cancer agents in medicinal chemistry. 2014; 14:1063-1064.
    • (2014) Anti-cancer agents in medicinal chemistry , vol.14 , pp. 1063-1064
    • Chen, J.1    Yakisich, J.S.2
  • 5
    • 0028261474 scopus 로고
    • Genetic aberrations in human brain tumors
    • Leon SP, Zhu J and Black PM. Genetic aberrations in human brain tumors. Neurosurgery. 1994; 34:708-722.
    • (1994) Neurosurgery , vol.34 , pp. 708-722
    • Leon, S.P.1    Zhu, J.2    Black, P.M.3
  • 10
    • 55349148686 scopus 로고    scopus 로고
    • Deletion of Trpm7 disrupts embryonic development and thymopoiesis without altering Mg2+ homeostasis
    • Jin J, Desai BN, Navarro B, Donovan A, Andrews NC and Clapham DE. Deletion of Trpm7 disrupts embryonic development and thymopoiesis without altering Mg2+ homeostasis. Science. 2008; 322:756-760.
    • (2008) Science , vol.322 , pp. 756-760
    • Jin, J.1    Desai, B.N.2    Navarro, B.3    Donovan, A.4    Andrews, N.C.5    Clapham, D.E.6
  • 13
    • 80052685766 scopus 로고    scopus 로고
    • Transient receptor potential melastatin 7 channels are involved in ginsenoside Rg3-induced apoptosis in gastric cancer cells
    • Kim BJ, Nah SY, Jeon JH, So I and Kim SJ. Transient receptor potential melastatin 7 channels are involved in ginsenoside Rg3-induced apoptosis in gastric cancer cells. Basic & clinical pharmacology & toxicology. 2011; 109:233-239.
    • (2011) Basic & clinical pharmacology & toxicology , vol.109 , pp. 233-239
    • Kim, B.J.1    Nah, S.Y.2    Jeon, J.H.3    So, I.4    Kim, S.J.5
  • 14
    • 77952958037 scopus 로고    scopus 로고
    • TRPM7 regulates the migration of human nasopharyngeal carcinoma cell by mediating Ca(2+) influx
    • Chen JP, Luan Y, You CX, Chen XH, Luo RC and Li R. TRPM7 regulates the migration of human nasopharyngeal carcinoma cell by mediating Ca(2+) influx. Cell calcium. 2010; 47:425-432.
    • (2010) Cell calcium , vol.47 , pp. 425-432
    • Chen, J.P.1    Luan, Y.2    You, C.X.3    Chen, X.H.4    Luo, R.C.5    Li, R.6
  • 17
    • 84872064588 scopus 로고    scopus 로고
    • Increase in serum Ca2+/Mg2+ ratio promotes proliferation of prostate cancer cells by activating TRPM7 channels
    • Sun Y, Selvaraj S, Varma A, Derry S, Sahmoun AE and Singh BB. Increase in serum Ca2+/Mg2+ ratio promotes proliferation of prostate cancer cells by activating TRPM7 channels. The Journal of biological chemistry. 2013; 288:255-263.
    • (2013) The Journal of biological chemistry , vol.288 , pp. 255-263
    • Sun, Y.1    Selvaraj, S.2    Varma, A.3    Derry, S.4    Sahmoun, A.E.5    Singh, B.B.6
  • 19
    • 84910675372 scopus 로고    scopus 로고
    • Cellular and Developmental Biology of TRPM7 Channel-Kinase: Implicated Roles in Cancer
    • Yee NS, Kazi AA and Yee RK. Cellular and Developmental Biology of TRPM7 Channel-Kinase: Implicated Roles in Cancer. Cells. 2014; 3:751-777.
    • (2014) Cells , vol.3 , pp. 751-777
    • Yee, N.S.1    Kazi, A.A.2    Yee, R.K.3
  • 21
    • 80655144731 scopus 로고    scopus 로고
    • Waixenicin A inhibits cell proliferation through magnesium-dependent block of transient receptor potential melastatin 7 (TRPM7) channels
    • Zierler S, Yao G, Zhang Z, Kuo WC, Porzgen P, Penner R, Horgen FD and Fleig A. Waixenicin A inhibits cell proliferation through magnesium-dependent block of transient receptor potential melastatin 7 (TRPM7) channels. The Journal of biological chemistry. 2011; 286:39328-39335.
    • (2011) The Journal of biological chemistry , vol.286 , pp. 39328-39335
    • Zierler, S.1    Yao, G.2    Zhang, Z.3    Kuo, W.C.4    Porzgen, P.5    Penner, R.6    Horgen, F.D.7    Fleig, A.8
  • 25
    • 58849121486 scopus 로고    scopus 로고
    • Biological and pharmacological activities of carvacrol and carvacrol bearing essential oils
    • Baser KH. Biological and pharmacological activities of carvacrol and carvacrol bearing essential oils. Current pharmaceutical design. 2008; 14:3106-3119.
    • (2008) Current pharmaceutical design , vol.14 , pp. 3106-3119
    • Baser, K.H.1
  • 26
    • 0038599791 scopus 로고
    • A Comparison of the Toxicity of Some Allyl, Propenyl, and Propyl Compounds in the Rat
    • Taylor JM, Jenner PM and Jones WI. A Comparison of the Toxicity of Some Allyl, Propenyl, and Propyl Compounds in the Rat. Toxicology and applied pharmacology. 1964; 6:378-387.
    • (1964) Toxicology and applied pharmacology , vol.6 , pp. 378-387
    • Taylor, J.M.1    Jenner, P.M.2    Jones, W.I.3
  • 27
    • 84870342079 scopus 로고    scopus 로고
    • Identification of CYP isoforms involved in the metabolism of thymol and carvacrol in human liver microsomes (HLMs)
    • Dong RH, Fang ZZ, Zhu LL, Ge GB, Cao YF, Li XB, Hu CM, Yang L and Liu ZY. Identification of CYP isoforms involved in the metabolism of thymol and carvacrol in human liver microsomes (HLMs). Die Pharmazie. 2012; 67:1002-1006.
    • (2012) Die Pharmazie , vol.67 , pp. 1002-1006
    • Dong, R.H.1    Fang, Z.Z.2    Zhu, L.L.3    Ge, G.B.4    Cao, Y.F.5    Li, X.B.6    Hu, C.M.7    Yang, L.8    Liu, Z.Y.9
  • 28
    • 34347218991 scopus 로고    scopus 로고
    • In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro
    • Liang CC, Park AY and Guan JL. In vitro scratch assay: a convenient and inexpensive method for analysis of cell migration in vitro. Nature protocols. 2007; 2:329-333.
    • (2007) Nature protocols , vol.2 , pp. 329-333
    • Liang, C.C.1    Park, A.Y.2    Guan, J.L.3
  • 29
    • 0021749110 scopus 로고
    • Cofilin, a protein in porcine brain that binds to actin filaments and inhibits their interactions with myosin and tropomyosin
    • Nishida E, Maekawa S and Sakai H. Cofilin, a protein in porcine brain that binds to actin filaments and inhibits their interactions with myosin and tropomyosin. Biochemistry. 1984; 23:5307-5313.
    • (1984) Biochemistry , vol.23 , pp. 5307-5313
    • Nishida, E.1    Maekawa, S.2    Sakai, H.3
  • 30
    • 0029859963 scopus 로고    scopus 로고
    • Dephosphorylation of serine 3 regulates nuclear translocation of cofilin
    • Nebl G, Meuer SC and Samstag Y. Dephosphorylation of serine 3 regulates nuclear translocation of cofilin. Journal of Biological Chemistry. 1996; 271:26276-26280.
    • (1996) Journal of Biological Chemistry , vol.271 , pp. 26276-26280
    • Nebl, G.1    Meuer, S.C.2    Samstag, Y.3
  • 32
    • 0028025563 scopus 로고
    • Apoptosis in cancer therapy: crossing the threshold
    • Fisher DE. Apoptosis in cancer therapy: crossing the threshold. Cell. 1994; 78:539-542.
    • (1994) Cell , vol.78 , pp. 539-542
    • Fisher, D.E.1
  • 34
    • 84925175304 scopus 로고    scopus 로고
    • TRPM7 channels regulate glioma stem cell through STAT3 and Notch signaling pathways
    • Liu M, Inoue K, Leng T, Guo S and Xiong ZG. TRPM7 channels regulate glioma stem cell through STAT3 and Notch signaling pathways. Cellular signalling. 2014; 26:2773-2781.
    • (2014) Cellular signalling , vol.26 , pp. 2773-2781
    • Liu, M.1    Inoue, K.2    Leng, T.3    Guo, S.4    Xiong, Z.G.5
  • 38
    • 22244467087 scopus 로고    scopus 로고
    • MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells
    • Chan JA, Krichevsky AM and Kosik KS. MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer research. 2005; 65:6029-6033.
    • (2005) Cancer research , vol.65 , pp. 6029-6033
    • Chan, J.A.1    Krichevsky, A.M.2    Kosik, K.S.3
  • 40
    • 84893676329 scopus 로고    scopus 로고
    • The effect of carvacrol on healthy neurons and N2a cancer cells: some biochemical, anticancerogenicity and genotoxicity studies
    • Aydin E, Turkez H and Keles MS. The effect of carvacrol on healthy neurons and N2a cancer cells: some biochemical, anticancerogenicity and genotoxicity studies. Cytotechnology. 2014; 66:149-157.
    • (2014) Cytotechnology , vol.66 , pp. 149-157
    • Aydin, E.1    Turkez, H.2    Keles, M.S.3
  • 41
    • 33745742247 scopus 로고    scopus 로고
    • Oregano, thyme and clove-derived flavors and skin sensitizers activate specific TRP channels
    • Xu H, Delling M, Jun JC and Clapham DE. Oregano, thyme and clove-derived flavors and skin sensitizers activate specific TRP channels. Nature neuroscience. 2006; 9:628-635.
    • (2006) Nature neuroscience , vol.9 , pp. 628-635
    • Xu, H.1    Delling, M.2    Jun, J.C.3    Clapham, D.E.4
  • 42
    • 84905457860 scopus 로고    scopus 로고
    • Carvacrol alleviates ischemia reperfusion injury by regulating the PI3K-Akt pathway in rats
    • Suo L, Kang K, Wang X, Cao Y, Zhao H, Sun X, Tong L and Zhang F. Carvacrol alleviates ischemia reperfusion injury by regulating the PI3K-Akt pathway in rats. PloS one. 2014; 9:e104043.
    • (2014) PloS one , vol.9
    • Suo, L.1    Kang, K.2    Wang, X.3    Cao, Y.4    Zhao, H.5    Sun, X.6    Tong, L.7    Zhang, F.8
  • 43
    • 84876930966 scopus 로고    scopus 로고
    • Carvacrol protects against acute myocardial infarction of rats via anti-oxidative and antiapoptotic pathways
    • Yu W, Liu Q and Zhu S. Carvacrol protects against acute myocardial infarction of rats via anti-oxidative and antiapoptotic pathways. Biological & pharmaceutical bulletin. 2013; 36:579-584.
    • (2013) Biological & pharmaceutical bulletin , vol.36 , pp. 579-584
    • Yu, W.1    Liu, Q.2    Zhu, S.3
  • 44
    • 84889065002 scopus 로고    scopus 로고
    • Carvacrol ameliorates thioacetamideinduced hepatotoxicity by abrogation of oxidative stress, inflammation, and apoptosis in liver of Wistar rats
    • Nafees S, Ahmad ST, Arjumand W, Rashid S, Ali N and Sultana S. Carvacrol ameliorates thioacetamideinduced hepatotoxicity by abrogation of oxidative stress, inflammation, and apoptosis in liver of Wistar rats. Human & experimental toxicology. 2013; 32:1292-1304.
    • (2013) Human & experimental toxicology , vol.32 , pp. 1292-1304
    • Nafees, S.1    Ahmad, S.T.2    Arjumand, W.3    Rashid, S.4    Ali, N.5    Sultana, S.6
  • 45
    • 84890148277 scopus 로고    scopus 로고
    • The effects of oral carvacrol treatment against H2O2 induced injury on isolated pancreas islet cells of rats
    • Dagli Gul AS, Fadillioglu E, Karabulut I, Yesilyurt A and Delibasi T. The effects of oral carvacrol treatment against H2O2 induced injury on isolated pancreas islet cells of rats. Islets. 2013; 5:149-155.
    • (2013) Islets , vol.5 , pp. 149-155
    • Dagli Gul, A.S.1    Fadillioglu, E.2    Karabulut, I.3    Yesilyurt, A.4    Delibasi, T.5
  • 46
    • 84860453259 scopus 로고    scopus 로고
    • Carvacrol-induced [Ca2+]i rise and apoptosis in human glioblastoma cells
    • Liang WZ and Lu CH. Carvacrol-induced [Ca2+]i rise and apoptosis in human glioblastoma cells. Life sciences. 2012; 90:703-711.
    • (2012) Life sciences , vol.90 , pp. 703-711
    • Liang, W.Z.1    Lu, C.H.2
  • 50
    • 0038049137 scopus 로고    scopus 로고
    • Tumour-cell invasion and migration: diversity and escape mechanisms
    • Friedl P and Wolf K. Tumour-cell invasion and migration: diversity and escape mechanisms. Nat Rev Cancer. 2003; 3:362-374.
    • (2003) Nat Rev Cancer , vol.3 , pp. 362-374
    • Friedl, P.1    Wolf, K.2
  • 51
    • 0036904661 scopus 로고    scopus 로고
    • Cell motility: insights from the backstage
    • Bailly M and Condeelis J. Cell motility: insights from the backstage. Nature cell biology. 2002; 4:E292-294.
    • (2002) Nature cell biology , vol.4 , pp. E292-294
    • Bailly, M.1    Condeelis, J.2
  • 52
    • 34247468876 scopus 로고    scopus 로고
    • Regulation of the actin cytoskeleton in cancer cell migration and invasion
    • Yamaguchi H and Condeelis J. Regulation of the actin cytoskeleton in cancer cell migration and invasion. Biochimica et biophysica acta. 2007; 1773:642-652.
    • (2007) Biochimica et biophysica acta , vol.1773 , pp. 642-652
    • Yamaguchi, H.1    Condeelis, J.2
  • 53
    • 34247468876 scopus 로고    scopus 로고
    • Regulation of the actin cytoskeleton in cancer cell migration and invasion
    • Yamaguchi H and Condeelis J. Regulation of the actin cytoskeleton in cancer cell migration and invasion. Biochimica et biophysica acta. 2007; 1773:642-652.
    • (2007) Biochimica et biophysica acta , vol.1773 , pp. 642-652
    • Yamaguchi, H.1    Condeelis, J.2
  • 54
    • 0034279330 scopus 로고    scopus 로고
    • Changes in tumorigenesis- and angiogenesis-related gene transcript abundance profiles in ovarian cancer detected by tailored high density cDNA arrays
    • Martoglio AM, Tom BD, Starkey M, Corps AN, Charnock-Jones DS and Smith SK. Changes in tumorigenesis- and angiogenesis-related gene transcript abundance profiles in ovarian cancer detected by tailored high density cDNA arrays. Mol Med. 2000; 6:750-765.
    • (2000) Mol Med , vol.6 , pp. 750-765
    • Martoglio, A.M.1    Tom, B.D.2    Starkey, M.3    Corps, A.N.4    Charnock-Jones, D.S.5    Smith, S.K.6
  • 55
    • 0042861598 scopus 로고    scopus 로고
    • Proteomic changes in renal cancer and co-ordinate demonstration of both the glycolytic and mitochondrial aspects of the Warburg effect
    • Unwin RD, Craven RA, Harnden P, Hanrahan S, Totty N, Knowles M, Eardley I, Selby PJ and Banks RE. Proteomic changes in renal cancer and co-ordinate demonstration of both the glycolytic and mitochondrial aspects of the Warburg effect. Proteomics. 2003; 3:1620-1632.
    • (2003) Proteomics , vol.3 , pp. 1620-1632
    • Unwin, R.D.1    Craven, R.A.2    Harnden, P.3    Hanrahan, S.4    Totty, N.5    Knowles, M.6    Eardley, I.7    Selby, P.J.8    Banks, R.E.9
  • 56
    • 0033811376 scopus 로고    scopus 로고
    • Identification of novel proteins associated with the development of chemoresistance in malignant melanoma using two-dimensional electrophoresis
    • Sinha P, Kohl S, Fischer J, Hutter G, Kern M, Kottgen E, Dietel M, Lage H, Schnolzer M and Schadendorf D. Identification of novel proteins associated with the development of chemoresistance in malignant melanoma using two-dimensional electrophoresis. Electrophoresis. 2000; 21:3048-3057.
    • (2000) Electrophoresis , vol.21 , pp. 3048-3057
    • Sinha, P.1    Kohl, S.2    Fischer, J.3    Hutter, G.4    Kern, M.5    Kottgen, E.6    Dietel, M.7    Lage, H.8    Schnolzer, M.9    Schadendorf, D.10
  • 57
    • 0033793141 scopus 로고    scopus 로고
    • Growth and migration markers of rat C6 glioma cells identified by serial analysis of gene expression
    • Gunnersen JM, Spirkoska V, Smith PE, Danks RA and Tan SS. Growth and migration markers of rat C6 glioma cells identified by serial analysis of gene expression. Glia. 2000; 32:146-154.
    • (2000) Glia , vol.32 , pp. 146-154
    • Gunnersen, J.M.1    Spirkoska, V.2    Smith, P.E.3    Danks, R.A.4    Tan, S.S.5
  • 60
    • 0034722329 scopus 로고    scopus 로고
    • Phosphorylation of ADF/cofilin abolishes EGF-induced actin nucleation at the leading edge and subsequent lamellipod extension
    • Zebda N, Bernard O, Bailly M, Welti S, Lawrence DS and Condeelis JS. Phosphorylation of ADF/cofilin abolishes EGF-induced actin nucleation at the leading edge and subsequent lamellipod extension. The Journal of cell biology. 2000; 151:1119-1128.
    • (2000) The Journal of cell biology , vol.151 , pp. 1119-1128
    • Zebda, N.1    Bernard, O.2    Bailly, M.3    Welti, S.4    Lawrence, D.S.5    Condeelis, J.S.6
  • 61
    • 12844269159 scopus 로고    scopus 로고
    • Actin-depolymerizing factor and cofilin-1 play overlapping roles in promoting rapid F-actin depolymerization in mammalian nonmuscle cells
    • Hotulainen P, Paunola E, Vartiainen MK and Lappalainen P. Actin-depolymerizing factor and cofilin-1 play overlapping roles in promoting rapid F-actin depolymerization in mammalian nonmuscle cells. Molecular biology of the cell. 2005; 16:649-664.
    • (2005) Molecular biology of the cell , vol.16 , pp. 649-664
    • Hotulainen, P.1    Paunola, E.2    Vartiainen, M.K.3    Lappalainen, P.4
  • 63
    • 70350374205 scopus 로고    scopus 로고
    • Invadosomes at a glance
    • Linder S. Invadosomes at a glance. Journal of cell science. 2009; 122:3009-3013.
    • (2009) Journal of cell science , vol.122 , pp. 3009-3013
    • Linder, S.1
  • 69
    • 84884708216 scopus 로고    scopus 로고
    • TRPM7 channel regulates PDGF-BB-induced proliferation of hepatic stellate cells via PI3K and ERK pathways
    • Fang L, Zhan S, Huang C, Cheng X, Lv X, Si H and Li J. TRPM7 channel regulates PDGF-BB-induced proliferation of hepatic stellate cells via PI3K and ERK pathways. Toxicology and applied pharmacology. 2013; 272:713-725.
    • (2013) Toxicology and applied pharmacology , vol.272 , pp. 713-725
    • Fang, L.1    Zhan, S.2    Huang, C.3    Cheng, X.4    Lv, X.5    Si, H.6    Li, J.7
  • 71
    • 84865339191 scopus 로고    scopus 로고
    • Identification of Ser/Thr phosphorylation sites in the C2-domain of phospholipase C gamma2 (PLCgamma2) using TRPM7-kinase
    • Deason-Towne F, Perraud AL and Schmitz C. Identification of Ser/Thr phosphorylation sites in the C2-domain of phospholipase C gamma2 (PLCgamma2) using TRPM7-kinase. Cellular signalling. 2012; 24:2070-2075.
    • (2012) Cellular signalling , vol.24 , pp. 2070-2075
    • Deason-Towne, F.1    Perraud, A.L.2    Schmitz, C.3
  • 74
    • 33846205171 scopus 로고    scopus 로고
    • A Ras inhibitor tilts the balance between Rac and Rho and blocks phosphatidylinositol 3-kinase-dependent glioblastoma cell migration
    • Goldberg L and Kloog Y. A Ras inhibitor tilts the balance between Rac and Rho and blocks phosphatidylinositol 3-kinase-dependent glioblastoma cell migration. Cancer research. 2006; 66(:11709-11717.
    • (2006) Cancer research , vol.66 , pp. 11709-11717
    • Goldberg, L.1    Kloog, Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.