Tanshinone IIA protects dopaminergic neurons against 6-hydroxydopamine-induced neurotoxicity through miR-153/NF-E2-related factor 2/antioxidant response element signaling pathway

Neuroscience

Volumn 303, Issue , 2015, Pages 489-502

  Zhang, X S ^a   Ha, S ^a   Wang, X L ^a   Shi, Y L ^a   Duan, S S ^a   Li, Z A ^a  

^a AFFILIATED HOSPITAL OF INNER MONGOLIA MEDICAL UNIVERSITY   (China)

Author keywords

6 OHDA; ARE; Nrf2; Oxidative stress; Parkinson's disease; Tanshinone IIA

Indexed keywords

CASPASE 3; CASPASE 9; CYTOCHROME C; HEME OXYGENASE 1; LACTATE DEHYDROGENASE; MICRORNA; MICRORNA 153; OXIDOPAMINE; REACTIVE OXYGEN METABOLITE; TANSHINONE IIA; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG; ABIETANE DERIVATIVE; APOMORPHINE; DOPAMINE; GLUTATHIONE; NEUROPROTECTIVE AGENT; NFE2L2 PROTEIN, MOUSE; TANSHINONE; TYROSINE 3 MONOOXYGENASE;

3' UNTRANSLATED REGION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; BIOACCUMULATION; CONTROLLED STUDY; CYTOPLASM; DOPAMINERGIC NERVE CELL; ENZYME ACTIVATION; ENZYME RELEASE; ENZYME SYNTHESIS; GCLC GENE; GCLM GENE; GENE; HO1 GENE; HUMAN; HUMAN CELL; IN VIVO STUDY; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; MOUSE; NERVE DEGENERATION; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; ANIMAL; APOPTOSIS; C57BL MOUSE; CELL SURVIVAL; DISEASE MODEL; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; NEUROBLASTOMA; NEUROTOXICITY SYNDROMES; PATHOLOGY; STEREOTYPY; TIME FACTOR;

ANIMALS; APOMORPHINE; APOPTOSIS; CELL SURVIVAL; DISEASE MODELS, ANIMAL; DITERPENES, ABIETANE; DOPAMINE; DOPAMINERGIC NEURONS; GENE EXPRESSION REGULATION; GLUTATHIONE; HUMANS; MALE; MICE; MICE, INBRED C57BL; NEUROBLASTOMA; NEUROPROTECTIVE AGENTS; NEUROTOXICITY SYNDROMES; NF-E2-RELATED FACTOR 2; OXIDOPAMINE; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; STEREOTYPED BEHAVIOR; TIME FACTORS; TYROSINE 3-MONOOXYGENASE;

EID: 84937875644     PISSN: 03064522     EISSN: 18737544     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2015.06.030     Document Type: Article

References (37)

1. Ambani L.M., Van Woert M.H., Murphy S. Brain peroxidase and catalase in Parkinson disease. Arch Neurol 1975, 32:114-118.
2. Andrew R., Watson D.G., Best S.A., Midgley J.M., Wenlong H., Petty R.K. The determination of hydroxydopamines and other trace amines in the urine of parkinsonian patients and normal controls. Neurochem Res 1993, 18:1175-1177.
3. Braun S., Hanselmann C., Gassmann M.G., auf dem Keller U., Born-Berclaz C., Chan K., Kan Y.W., Werner S. Nrf2 transcription factor, a novel target of keratinocyte growth factor action which regulates gene expression and inflammation in the healing skin wound. Mol Cell Biol 2002, 22:5492-5505.
4. Chumanov R.S., Burgess R.R. Expression, purification, and refolding of active Nrf2 transcription factor fused to protein transduction TAT tag. Protein Expr Purif 2010, 74:280-288.
5. Clutton S. The importance of oxidative stress in apoptosis. Br Med Bull 1997, 53:662-668.
6. Cohen G., Heikkila R.E. The generation of hydrogen peroxide, superoxide radical, and hydroxyl radical by 6-hydroxydopamine, dialuric acid, and related cytotoxic agents. J Biol Chem 1974, 249:2447-2452.
7. Cuadrado A. Structural and functional characterization of NRF2 degradation by glycogen synthase kinase 3/beta-TrCP. Free Radic Biol Med 2015.
8. Curtin J.F., Donovan M., Cotter T.G. Regulation and measurement of oxidative stress in apoptosis. J Immunol Methods 2002, 265:49-72.
9. Curtius H.C., Wolfensberger M., Steinmann B., Redweik U., Siegfried J. Mass fragmentography of dopamine and 6-hydroxydopamine. Application to the determination of dopamine in human brain biopsies from the caudate nucleus. J Chromatogr 1974, 99:529-540.
10. Deumens R., Blokland A., Prickaerts J. Modeling Parkinson's disease in rats: an evaluation of 6-OHDA lesions of the nigrostriatal pathway. Exp Neurol 2002, 175:303-317.
11. Dexter D.T., Carter C.J., Wells F.R., Javoy-Agid F., Agid Y., Lees A., Jenner P., Marsden C.D. Basal lipid peroxidation in substantia nigra is increased in Parkinson's disease. J Neurochem 1989, 52:381-389.
12. Doxakis E. Post-transcriptional regulation of alpha-synuclein expression by mir-7 and mir-153. J Biol Chem 2010, 285:12726-12734.
13. Hong H.J., Liu J.C., Cheng T.H., Chan P. Tanshinone IIA attenuates angiotensin II-induced apoptosis via Akt pathway in neonatal rat cardiomyocytes. Acta Pharmacol Sin 2010, 31:1569-1575.
14. Jenner P., Olanow C.W. Understanding cell death in Parkinson's disease. Ann Neurol 1998, 44:S72-S84.
15. Ji Y., He J., Zhou Q., Chen J., Li Q., Zhu J., Liu H. The inhibiting effect and its molecular mechanism of Tanshinone on human lung cancer cell line in vitro. Zhongguo Fei Ai Za Zhi 2008, 11:202-205.
16. Jing X., Shi H., Zhang C., Ren M., Han M., Wei X., Zhang X., Lou H. Dimethyl fumarate attenuates 6-OHDA-induced neurotoxicity in SH-SY5Y cells and in animal model of Parkinson's disease by enhancing Nrf2 activity. Neuroscience 2015, 286:131-140.
17. Kang K.W., Lee S.J., Park J.W., Kim S.G. Phosphatidylinositol 3-kinase regulates nuclear translocation of NF-E2-related factor 2 through actin rearrangement in response to oxidative stress. Mol Pharmacol 2002, 62:1001-1010.
18. Kish S.J., Morito C., Hornykiewicz O. Glutathione peroxidase activity in Parkinson's disease brain. Neurosci Lett 1985, 58:343-346.
19. Kobayashi A., Kang M.I., Okawa H., Ohtsuji M., Zenke Y., Chiba T., Igarashi K., Yamamoto M. Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2. Mol Cell Biol 2004, 24:7130-7139.
20. Kumar H., Koppula S., Kim I.S., More S.V., Kim B.W., Choi D.K. Nuclear factor erythroid 2-related factor 2 signaling in Parkinson disease: a promising multi therapeutic target against oxidative stress, neuroinflammation and cell death. CNS Neurol Disord Drug Targets 2012, 11:1015-1029.
21. Li J., Johnson D., Calkins M., Wright L., Svendsen C., Johnson J. Stabilization of Nrf2 by tBHQ confers protection against oxidative stress-induced cell death in human neural stem cells. Toxicol Sci 2005, 83:313-328.
22. Liang Y., Ridzon D., Wong L., Chen C. Characterization of microRNA expression profiles in normal human tissues. BMC Genomics 2007, 8:166.
23. Lin R., Wang W.R., Liu J.T., Yang G.D., Han C.J. Protective effect of tanshinone IIA on human umbilical vein endothelial cell injured by hydrogen peroxide and its mechanism. J Ethnopharmacol 2006, 108:217-222.
24. Liu L., Sun T., Liu Z., Chen X., Zhao L., Qu G., Li Q. Traumatic brain injury dysregulates microRNAs to modulate cell signaling in rat hippocampus. PLoS One 2014, 9:e103948.
25. Long J.M., Ray B., Lahiri D.K. MicroRNA-153 physiologically inhibits expression of amyloid-beta precursor protein in cultured human fetal brain cells and is dysregulated in a subset of Alzheimer disease patients. J Biol Chem 2012, 287:31298-31310.
26. Lou H., Jing X., Wei X., Shi H., Ren D., Zhang X. Naringenin protects against 6-OHDA-induced neurotoxicity via activation of the Nrf2/ARE signaling pathway. Neuropharmacology 2014, 79:380-388.
27. Moi P., Chan K., Asunis I., Cao A., Kan Y.W. Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region. Proc Natl Acad Sci USA 1994, 91:9926-9930.
28. Narasimhan M., Patel D., Vedpathak D., Rathinam M., Henderson G., Mahimainathan L. Identification of novel microRNAs in post-transcriptional control of Nrf2 expression and redox homeostasis in neuronal, SH-SY5Y cells. PLoS One 2012, 7:e51111.
29. Narasimhan M., Riar A.K., Rathinam M.L., Vedpathak D., Henderson G., Mahimainathan L. Hydrogen peroxide responsive miR153 targets Nrf2/ARE cytoprotection in paraquat induced dopaminergic neurotoxicity. Toxicol Lett 2014, 228:179-191.
30. Qin X.Y., Li T., Yan L., Liu Q.S., Tian Y. Tanshinone IIA protects against immune-mediated liver injury through activation of T-cell subsets and regulation of cytokines. Immunopharmacol Immunotoxicol 2010, 32:51-55.
31. Ramsey C.P., Glass C.A., Montgomery M.B., Lindl K.A., Ritson G.P., Chia L.A., Hamilton R.L., Chu C.T., Jordan-Sciutto K.L. Expression of Nrf2 in neurodegenerative diseases. J Neuropathol Exp Neurol 2007, 66:75-85.
32. Ren B., Zhang Y.X., Zhou H.X., Sun F.W., Zhang Z.F., Wei Z., Zhang C.Y., Si D.W. Tanshinone IIA prevents the loss of nigrostriatal dopaminergic neurons by inhibiting NADPH oxidase and iNOS in the MPTP model of Parkinson's disease. J Neurol Sci 2015, 348:142-152.
33. Roy Chowdhury S., Sengupta S., Biswas S., Sinha T.K., Sen R., Basak R.K., Adhikari B., Bhattacharyya A. Bacterial fucose-rich polysaccharide stabilizes MAPK-mediated Nrf2/Keap1 signaling by directly scavenging reactive oxygen species during hydrogen peroxide-induced apoptosis of human lung fibroblast cells. PLoS One 2014, 9:e113663.
34. Signore A.P., Weng Z., Hastings T., Van Laar A.D., Liang Q., Lee Y.J., Chen J. Erythropoietin protects against 6-hydroxydopamine-induced dopaminergic cell death. J Neurochem 2006, 96:428-443.
35. Sung H.J., Choi S.M., Yoon Y., An K.S. Tanshinone IIA, an ingredient of Salvia miltiorrhiza BUNGE, induces apoptosis in human leukemia cell lines through the activation of caspase-3. Exp Mol Med 1999, 31:174-178.
36. Yates M.S., Kensler T.W. Chemopreventive promise of targeting the Nrf2 pathway. Drug News Perspect 2007, 20:109-117.
37. Zhu K.Y., Fu Q., Leung K.W., Wong Z.C., Choi R.C., Tsim K.W. The establishment of a sensitive method in determining different neurotransmitters simultaneously in rat brains by using liquid chromatography-electrospray tandem mass spectrometry. J Chromatogr B Analyt Technol Biomed Life Sci 2011, 879:737-742.