IL-1β Induces MMP-9-Dependent Brain Astrocytic Migration via Transactivation of PDGF Receptor/NADPH Oxidase 2-Derived Reactive Oxygen Species Signals

Molecular Neurobiology

Volumn 52, Issue 1, 2015, Pages 303-317

  Yang, Chuen Mao ^a   Hsieh, Hsi Lung ^b   Yu, Ping Hsien ^a   Lin, Chih Chung ^a   Liu, Shiau Wen ^a  

^a CHANG GUNG UNIVERSITY COLLEGE OF MEDICINE   (Taiwan)

^b CHANG GUNG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

Author keywords

Astrocytes; Brain inflammation; Interleukin 1 ; Matrix metalloproteinase 9; NADPH oxidase; Reactive oxygen species

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 2; GELATINASE B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; MEMBRANE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROTEIN KINASE B; PROTEIN P47PHOX; PROTEIN TYROSINE KINASE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE 2; TRANSCRIPTION FACTOR AP 1; UNCLASSIFIED DRUG; CYBB PROTEIN, RAT; PROTEIN KINASE P60; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

ANIMAL CELL; ARTICLE; ASTROCYTE; CELL MIGRATION; CELL STIMULATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME REGULATION; NEWBORN; NONHUMAN; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSACTIVATION; UPREGULATION; ZYMOGRAPHY; ANIMAL; BIOLOGICAL MODEL; BRAIN; CELL MOTION; CYTOLOGY; DRUG EFFECTS; ENZYMOLOGY; GENETICS; METABOLISM; PROTEIN TRANSPORT; TRANSCRIPTION INITIATION;

ANIMALS; ASTROCYTES; BRAIN; CELL MOVEMENT; INTERLEUKIN-1BETA; MATRIX METALLOPROTEINASE 9; MEMBRANE GLYCOPROTEINS; MITOGEN-ACTIVATED PROTEIN KINASES; MODELS, BIOLOGICAL; NADPH OXIDASE; NF-KAPPA B; PROTEIN TRANSPORT; PROTO-ONCOGENE PROTEINS PP60(C-SRC); RATS; REACTIVE OXYGEN SPECIES; RECEPTORS, PLATELET-DERIVED GROWTH FACTOR; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR AP-1; TRANSCRIPTIONAL ACTIVATION;

EID: 84937863840     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-014-8838-y     Document Type: Article

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