Studies of alternative isoforms provide insight into TDP-43 autoregulation and pathogenesis

RNA

Volumn 21, Issue 8, 2015, Pages 1419-1432

  D'Alton, Simon ^a   Altshuler, Marcelle ^a   Lewis, Jada ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

Author keywords

ALS; Autoregulation; FTLD; Splicing; TDP 43

Indexed keywords

MESSENGER RNA; POLYADENYLIC ACID; SMALL INTERFERING RNA; TAR DNA BINDING PROTEIN; 3' UNTRANSLATED REGION; DNA BINDING PROTEIN; TDP-43 PROTEIN, HUMAN; TDP-43 PROTEIN, MOUSE;

3' UNTRANSLATED REGION; ALTERNATIVE RNA SPLICING; AMINO TERMINAL SEQUENCE; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; AUTOREGULATION; CARBOXY TERMINAL SEQUENCE; CELLULAR DISTRIBUTION; HUMAN; INTRON; NONHUMAN; PATHOGENESIS; POLYADENYLATION; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN RNA BINDING; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SPLICING; ANIMAL; CELL LINE; DISEASE MODEL; FRONTOTEMPORAL LOBAR DEGENERATION; GENETICS; HEK293 CELL LINE; HELA CELL LINE; HOMEOSTASIS; METABOLISM; MOUSE; MUTATION;

3' UNTRANSLATED REGIONS; ALTERNATIVE SPLICING; AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; CELL LINE; DISEASE MODELS, ANIMAL; DNA-BINDING PROTEINS; FRONTOTEMPORAL LOBAR DEGENERATION; HEK293 CELLS; HELA CELLS; HOMEOSTASIS; HUMANS; INTRONS; MICE; MUTATION; RNA, MESSENGER;

EID: 84937847279     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.047647.114     Document Type: Article

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