In Vivo Senescence in the Sbds-Deficient Murine Pancreas: Cell-Type Specific Consequences of Translation Insufficiency

PLoS Genetics

Volumn 11, Issue 6, 2015, Pages

  Tourlakis, Marina E ^a,b   Zhang, Siyi ^a,b   Ball, Heather L ^a   Gandhi, Rikesh ^a   Liu, Hongrui ^a,b   Zhong, Jian ^a   Yuan, Julie S ^a   Guidos, Cynthia J ^a   Durie, Peter R ^b   Rommens, Johanna M ^a,b  

^a HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN P53; PROTEIN; SBDS PROTEIN, MOUSE; TRANSFORMING GROWTH FACTOR BETA;

ACINAR CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL PROLIFERATION; CELL SIZE; CONTROLLED STUDY; DISEASE SEVERITY; EMBRYO; ENZYME SYNTHESIS; GENOTYPE PHENOTYPE CORRELATION; HETEROZYGOSITY; IN VIVO STUDY; MOUSE; NONHUMAN; PERINATAL PERIOD; PHENOTYPE; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN SYNTHESIS; SENESCENCE; SHWACHMAN SYNDROME; ANIMAL; BONE MARROW DISEASE; C57BL MOUSE; CELL AGING; CELL CULTURE; EXOCRINE PANCREATIC INSUFFICIENCY; GENETICS; GROWTH, DEVELOPMENT AND AGING; LIPOMATOSIS; METABOLISM; PANCREAS; PATHOLOGY; PHYSIOLOGY; RIBOSOME;

MURINAE;

ACINAR CELLS; ANIMALS; APOPTOSIS; BONE MARROW DISEASES; CELL AGING; CELLS, CULTURED; EXOCRINE PANCREATIC INSUFFICIENCY; LIPOMATOSIS; MICE; MICE, INBRED C57BL; PANCREAS; PROTEIN BIOSYNTHESIS; PROTEINS; RIBOSOMES; TRANSFORMING GROWTH FACTOR BETA; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84937788892     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1005288     Document Type: Article

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