Pluripotent stem cell models of shwachman-diamond syndrome reveal a common mechanism for pancreatic and hematopoietic dysfunction

Cell Stem Cell

Volumn 12, Issue 6, 2013, Pages 727-736

  Tulpule, Asmin ^a,b,d   Kelley, James M ^c   Lensch, M William ^a,d,e   McPherson, Jade ^a,d   Park, In Hyun ^f   Hartung, Odelya ^a,d   Nakamura, Tomoka ^g   Schlaeger, Thorsten M ^a,d   Shimamura, Akiko ^a,g,h   Daley, George Q ^a,b,d,e  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c BRIGHAM AND WOMEN S HOSPITAL   (United States)

^d HARVARD STEM CELL INSTITUTE   (United States)

^e HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^f YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g Fred Hutchinson Cancer Research Center   (United States)

^h SEATTLE CHILDREN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEINASE; PEPTIDE HYDROLASE; PROTEINASE INHIBITOR;

ALTERNATIVE RNA SPLICING; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CELL FATE; CELL MATURATION; CONTROLLED STUDY; EMBRYONIC STEM CELL; EXOCRINE CELL; FIBROBLAST CULTURE; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; GENE EXPRESSION; HEMATOPOIESIS; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IN VITRO STUDY; PANCREAS EXOCRINE INSUFFICIENCY; PHENOTYPE; PHENOTYPIC VARIATION; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RIBOSOME SUBUNIT; SHWACHMAN SYNDROME; TRANSGENE; WESTERN BLOTTING; BIOLOGICAL MODEL; BONE MARROW DISEASE; CELL CULTURE; ENZYMOLOGY; HEMATOPOIETIC STEM CELL; LIPOMATOSIS; METABOLISM; PANCREAS; PATHOLOGY; PATHOPHYSIOLOGY;

BONE MARROW DISEASES; CELL DIFFERENTIATION; CELLS, CULTURED; EXOCRINE PANCREATIC INSUFFICIENCY; HEMATOPOIETIC STEM CELLS; HUMANS; INDUCED PLURIPOTENT STEM CELLS; LIPOMATOSIS; MODELS, BIOLOGICAL; PANCREAS; PEPTIDE HYDROLASES; PROTEASE INHIBITORS;

EID: 84878820048     PISSN: 19345909     EISSN: 18759777     Source Type: Journal    
DOI: 10.1016/j.stem.2013.04.002     Document Type: Article

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