Cerium oxide nanoparticles alleviate oxidative stress and decreases Nrf-2/HO-1 in D-GALN/LPS induced hepatotoxicity

Biomedicine and Pharmacotherapy

Volumn 73, Issue , 2015, Pages 80-86

  Hashem, Reem M ^a   Rashd, Laila A ^b   Hashem, Khalid S ^c   Soliman, Hatem M ^a  

^a Beni Suef University   (Egypt)

^b CAIRO UNIVERSITY   (Egypt)

^c Beni Suef University   (Egypt)

Author keywords

Cerium oxide nanoparticles; D galactoseamine; Hepatotoxicity; HO 1; Lipopolysaccharide; Nrf 2

Indexed keywords

CATALASE; CERIUM OXIDE NANOPARTICLE; GALACTOSAMINE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; HEME OXYGENASE 1; INDUCIBLE NITRIC OXIDE SYNTHASE; LIPOPOLYSACCHARIDE; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; TRANSCRIPTION FACTOR NRF2; CERIC OXIDE; CERIUM; HMOX1 PROTEIN, HUMAN; METAL NANOPARTICLE; NFE2L2 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DNA FRAGMENTATION; GENE EXPRESSION; HISTOPATHOLOGY; LIVER FUNCTION; LIVER HEMORRHAGE; LIVER PROTECTION; LIVER SINUSOID; LIVER TOXICITY; MALE; NEUTROPHIL CHEMOTAXIS; NONHUMAN; NUCLEOCYTOPLASMIC TRANSPORT; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION; TISSUE DEGENERATION; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; DRUG-INDUCED LIVER INJURY; LIPID PEROXIDATION; METABOLISM; PHYSIOLOGY; WISTAR RAT;

ANIMALS; CERIUM; DRUG-INDUCED LIVER INJURY; GALACTOSAMINE; HEME OXYGENASE-1; LIPID PEROXIDATION; LIPOPOLYSACCHARIDES; MALE; METAL NANOPARTICLES; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; RATS; RATS, WISTAR;

EID: 84937777669     PISSN: 07533322     EISSN: 19506007     Source Type: Journal    
DOI: 10.1016/j.biopha.2015.05.006     Document Type: Article

References (49)

1. Nel A., Xia T., Mädler L., Li N. Toxic potential of materials at the nanolevel. Science 2006, 311(5761):622-627.
2. Chen J., Patil S., Seal S., McGinnis J.F. Rare earth nanoparticles prevent retinal degeneration induced by intracellular peroxides. Nat. Nanotechnol. 2006, 1(2):142-150.
3. Singh N., Cohen C.A., Rzigalinski B.A. Treatment of neurodegenerative disorders with radical nanomedicine. Ann. N. Y. Acad. Sci. 2007, 1122:219-230.
4. Patil S., Sandberg A., Heckert E., Self W., Seal S. Protein adsorption and cellular uptake of cerium oxide nanoparticles as a function of zeta potential. Biomaterials 2007, 28(31):4600-4607.
5. Fu P.P., Xia Q., Lin G., Chou M.W. Pyrrolizidine alkaloids-enotoxicity, metabolism enzymes, metabolic activation, and mechanisms. Drug. Metab. Rev. 2004, 36(1):1-55.
6. Morikawa A., Koide N., Sugiyama T., Mu M.M., Hassan F., Islam S., Ito H., Mori I., Yoshida T., Yokochi T. The enhancing action of D-galactoseamine on lipopolysaccharide-induced nitric oxide production in RAW 264.7 macrophage cells. FEMS. Immunol. Med. Microbiol. 2004, 41(3):211-218.
7. Wilhelm E.A., Jesse C.R., Nogueira C.W. Protective effect of p-methoxyl-diphenyl diselenide in lethal acute liver failure induced by lipopolysaccharide and D-galactoseamine in mice. Fundam. Clin. Pharmacol. 2009, 23(6):727-734.
8. Wilhelm E.A., Jesse C.R., Roman S.S., Nogueira C.W., Savegnago L. Hepatoprotective effect of 3-alkynyl selenophene on acute liver injury induced by D-galactoseamine and lipopolysaccharide. Exp. Mol. Pathol. 2009, 87(1):20-26.
9. Han D., Hanawa N., Saberi B., Kaplowitz N. Mechanisms of liver injury. III. Role of glutathione redox status in liver injury. Am. J. Physiol. Gastrointest. Liver. Physiol. 2006, 291(1):G1-G7.
10. Reddy P.V., Lungu G., Kuang X., Stoica G., Wong P.K. Neuroprotective effects of the drug GVT (monosodium luminol) is mediated by the stabilization of Nrf2 in astrocytes. Neurochem. Int. 2010, 56(6-7):780-788.
11. Maines M.D., Gibbs P.E. 30 some years of heme oxygenase: from a "molecular wrecking ball" to a "mesmerizing" trigger of cellular events. Biochem. Biophys. Res. Commun. 2005, 338(1):568-577.
12. Farombi E.O., Shrotriya S., Na H.K., Kim S.H., Surh Y.J. Curcumin attenuates dimethylnitrosamine- induced liver injury in rats through Nrf2-mediated induction of heme oxygenase-1. Food. Chem. Toxicol. 2008, 46(4):1279-1287.
13. Ishizaki-Koizumi S., Sonaka I., Takei Y., Ikejima K., Sato N. The glycine analogue, aminomethanesulfonic acid, inhibits LPS-induced production of TNF-alpha in isolated rat Kupffer cells and exerts hepatoprotective effects in mice. Biochem. Biophys. Res. Commun. 2004, 322(2):514-519.
14. Yoshida T., Abe K., Ikeda T., Matsushita T., Wake K., Sato T., Sato T., Inoue H. Inhibitory effect of glycyrrhizin on lipopolysaccharide and d-galactoseamine-induced mouse liver injury. Eur. J. Pharmacol. 2007, 576(1-3):136-142.
15. Roland C.R., Naziruddin B., Mohanakumar T., Flye M.W. Gadolinium chloride inhibits Kupffer cell nitric oxide synthase (iNOS) induction. J. Leukoc. Biol. 1996, 60(4):487-492.
16. Fukuda T., Mogami A., Tanaka H., Yoshikawa T., Hisadome M., Komatsu H. Y-40138, a multiple cytokine production modulator, protects against D-galactoseamine and lipopolysaccharide-induced hepatitis. Life Sci. 2006, 79(9):822-827.
17. Amin K.A., Hassan M.S., Awad el-ST, Hashem K.S. The protective effects of cerium oxide nanoparticles against hepatic oxidative damage induced by monocrotaline. Int. J. Nanomed. 2011, 6:143-149.
18. Gella F.J., Olivella T., Cruz Pastor M., Arenas J., Moreno R., Durban R., Gomez J.A. A simple procedure for the routine determination of aspartate aminotransferase and alanine aminotransferase with pyridoxal phosphate. Clin. Chim. Acta 1985, 153(3):241-247.
19. Kenneth J.L., Thomas D.S. Analysis of relative gene expression data using real-time quantitative PCR and the 2δδC T. METHODS 2001, 25:402-408.
20. Wang J., Edeen K., Manzer R., Chang Y., Wang S., Chen X., Funk C.J., Cosgrove G.P., Fang X., Mason R.J. Differentiated human alveolar epithelial cells and reversibility of their phenotype in vitro. Am. J. Respir. Cell. Mol. Biol. 2007, 36(6):661-668.
21. Beutler E., Duron O., Kelly B.M. Improved method for the determination of blood glutathione. J. Lab. Clin. Med. 1963, 61:882-888.
22. Long W.K., Carson P.E. Increased erythrocyte glutathione reductase activity in diabetes mellitus. Biochem. Biophys. Res. Commun. 1961, 5(5):394-399.
23. Aebi H. Catalase in vitro. Methods Enzymol. 1984, 105:121-126.
24. Nishikimi M., Roa N.A., Yogi K. Measurement of superoxide dismutase. Biochem. Biophys. Res. Commun. 1972, 46:849-854.
25. Satoh K. Serum lipid peroxide in cerebrovascular disorders determined by a new colorimetric method. Clin. Chim. Acta 1978, 90(1):37-43.
26. Burton K. A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid. Biochem. J. 1956, 62:315-327.
27. Bancroft J.D., Gamble M. Theory and practice of histological techniques 2008, 319. Churchill Livingstone, London. 6th edition.
28. Wang H., Li Y. Protective effect of bicyclol on acute hepatic failure induced by lipopolysaccharide and D-galactoseamine in mice. Eur. J. Pharmacol. 2006, 534(1-3):194-201.
29. Larson I.S. Acetaminophen hepatotoxicity. Clin. Liver. Dis. 2007, 11(3):525-548.
30. Ghosh A., Sil P.C. Protection of acetaminophen induced mitochondrial dysfunctions and hepatic necrosis via Akt-NF-kappaB pathway: role of a novel plant protein. Chem. Biol. Interact. 2009, 177(2):96-106.
31. Neihörster M., Inoue M., Wendel A. A link between extracellular reactive oxygen and endotoxin-induced release of tumour necrosis factor alpha in vivo. Biochem. Pharmacol. 1992, 43(5):1151-1154.
32. Yamasaki T., Li I., Lau B. Garlic compounds protect vascular endothelial cells from hydrogen peroxide-induced oxidant injury. Phytother. Res. 1994, 8:408-412.
33. El-Sokkary G.H., Omar H.M., Hassanein A.F., Cuzzocrea S., Reiter R.J. Melatonin reduces oxidative damage and increases survival of mice infected with Schistosoma mansoni. Free Radic. Biol. Med. 2002, 32(4):319-332.
34. Das J., Ghosh J., Manna P., Sil P.C. Taurine provides antioxidant defense against NaF-induced cytotoxicity in murine hepatocytes. Pathophysiology 2008, 15(3):181-190.
35. Szabó C., Ohshima H. DNA damage induced by peroxynitrite: subsequent biological effects. Nitric Oxide 1997, 1(5):373-385.
36. Pacher P., Beckman J.S., Liaudet L. Nitric oxide and peroxynitrite in health and disease. Physiol. Rev. 2007, 87(1):315-424.
37. Pradeep H.A., Khan S., Ravikumar K., Ahmed M.F., Rao M.S., Kiranmai M., Reddy D.S., Ahamed S.R., Ibrahim M. Hepatoprotective evaluation of Anogeissus latifolia: in vitro and in vivo studies. World J. Gastroenterol. 2009, 15(38):4816-4822.
38. Dufour D.R., Lott J.A., Nolte F.S., Gretch D.R., Koff R.S., Seeff L.B. Diagnosis and monitoring of hepatic injury. I. Performance characteristics of laboratory tests. Clin. Chem. 2000, 46(12):2027-2049.
39. Banerjee S.K., Dinda A.K., Manchanda S.C., Maulik S.K. Chronic garlic administration protects rat heart against oxidative stress induced by ischemic reperfusion injury. BMC Pharmacol. 2002, 2:16.
40. Heckert E.G., Karakoti A.S., Seal S., Self W. The role of cerium redox state in the SOD mimetic activity of nanoceria. Biomaterials 2008, 29(18):2705-2709.
41. Choi J.H., Kang J.W., Kim D.W., Sung Y.K., Lee S.M. Protective effects of Mg-CUD against D-galactosamine-induced hepatotoxicity in rats. Eur. J. Pharmacol. 2011, 657(1-3):138-143.
42. Kensler T.W., Wakabayashi N., Biswal S. Cell survival responses to environmental stresses via the Keap1-Nrf2-ARE pathway. Annu. Rev. Pharmacol. Toxicol. 2007, 47:89-116.
43. Aleksunes L.M., Manautou J.E. Emerging role of Nrf2 in protecting against hepatic and gastrointestinal disease. Toxicol. Pathol. 2007, 35:459-473.
44. Ishii T., Itoh K., Takahashi S., Sato H., Yanagawa T., Katoh Y., Bannai S., Yamamoto M. Transcription factor Nrf2 coordinately regulates a group of oxidative stress-inducible genesin macrophages. J. Biol. Chem. 2000, 275(21):16023-16029.
45. Das M., Patil S., Bhargava N., Kang J.F., Riedel L.M., Seal S., Hickman J.J. Auto-catalytic ceria nanoparticles offer neuroprotection to adult rat spinal cord neurons. Biomaterials 2007, 28(10):1918-1925.
46. Karakoti A.S., Monteiro-Riviere N.A., Aggarwal R., Davis J.P., Narayan R.J., Self W.T., McGinnis J., Seal S. Nanoceria as antioxidant: synthesis and biomedical applications. JOM (1989) 2008, 60(3):33-37.
47. Colon J., Herrera L., Smith J., Patil S., Komanski C., Kupelian P., Seal S., Jenkins D.W., Baker C.H. Protection from radiation-induced pneumonitis using cerium oxide nanoparticles. Nanomedicine 2009, 5(2):225-231.
48. Schubert D., Dargusch R., Raitano J., Chan S.W. Cerium and yttrium oxide nanoparticles are neuroprotective. Biochem. Biophys. Res. Commun. 2006, 342(1):86-91.
49. Becker S., Soukup J.M., Gallagher J.E. Differential particulate air pollution induced oxidant stress in human granulocytes, monocytes and alveolar macrophages. Toxicol. In Vitro 2002, 16(3):209-218.