Y-40138, a multiple cytokine production modulator, protects against d-galactosamine and lipopolysaccharide-induced hepatitis

Life Sciences

Volumn 79, Issue 9, 2006, Pages 822-827

  Fukuda, Tetsuko ^a   Mogami, Akira ^a   Tanaka, Hideki ^a   Yoshikawa, Tsutomu ^a   Hisadome, Masao ^a   Komatsu, Hirotsugu ^a  

^a MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

Author keywords

D GalN LPS; hepatitis; IL 10; MCP 1; TNF ; Y 40138

Indexed keywords

ALANINE AMINOTRANSFERASE; GALACTOSAMINE; IMMUNOMODULATING AGENT; INTERLEUKIN 10; LIPOPOLYSACCHARIDE; MONOCYTE CHEMOTACTIC PROTEIN 1; N [1 [4 [4 (PYRIMIDIN 2 YL)PIPERAZIN 1 YL]METHYLPHENYL]CYCLOPROPYL] ACETAMIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; Y 40138;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; CELL INTERACTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFECT; DRUG MECHANISM; FEMALE; HEPATITIS; HISTOLOGY; IMMUNOREGULATION; LIVER INJURY; MACROPHAGE; MOUSE; NONHUMAN; SURVIVAL; T LYMPHOCYTE; TREATMENT OUTCOME;

ACETAMIDES; ALANINE TRANSAMINASE; ANIMALS; CELL DEATH; CHEMOKINE CCL2; CHEMOKINES; COCULTURE TECHNIQUES; CYTOKINES; FEMALE; GALACTOSAMINE; HEPATITIS, TOXIC; HEPATOCYTES; LIPOPOLYSACCHARIDES; LIVER; MACROPHAGES; MICE; MICE, INBRED BALB C; PIPERAZINES; T-LYMPHOCYTES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33745698177     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2006.03.025     Document Type: Article

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