Synthesis of novel C5-curcuminoid-fatty acid conjugates and mechanistic investigation of their anticancer activity

Bioorganic and Medicinal Chemistry Letters

Volumn 25, Issue 10, 2015, Pages 2174-2180

  Sanabria Ríos, David J ^a   Rivera Torres, Yaritza ^a   Rosario, Joshua ^a   Ríos, Camille ^a   Gutierrez, Ricardo ^a   Carballeira, Néstor M ^b   Vélez, Christian ^c   Zayas, Beatriz ^c   Álvarez Colón, Félix ^d   Ortiz Soto, Gabriela ^d   Serrano, Victor ^d   Altieri Rivera, Joanne ^d   Ríos Olivares, Eddy ^d   Rodríguez, José W ^d  

^a INTER AMERICAN UNIVERSITY OF PUERTO RICO   (Puerto Rico)

^b UNIVERSITY OF PUERTO RICO   (Puerto Rico)

^c UNIVERSIDAD METROPOLITANA   (United States)

^d Universidad Central del Caribe School of Medicine   (Puerto Rico)

Author keywords

Anticancer agents; Apoptosis; C5 curcuminoids synthesis; DNA topoisomerase I; NF B

Indexed keywords

ANTINEOPLASTIC AGENT; CURCUMIN; FATTY ACID;

APOPTOSIS; CHEMISTRY; DRUG EFFECTS; HUMAN; SYNTHESIS; TUMOR CELL LINE;

ANTINEOPLASTIC AGENTS; APOPTOSIS; CELL LINE, TUMOR; CURCUMIN; FATTY ACIDS; HUMANS;

EID: 84937761858     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2015.03.065     Document Type: Article

References (36)

1. American Cancer Society Cancer Facts & Figures 2014 2014 American Cancer Society Atlanta
2. N.R. Figueroa-Vallés Bulletin of Registry of Cancer v.1 (2) 2008 Department of Health of Puerto Rico San Juan 3
3. B.B. Aggarwal, A. Kumar, and A.C. Bharti Anticancer Res. 23 2003 363
4. B.B. Aggarwal Cancer Biol. Ther. 7 2008 1436
5. G. Bar-Sela, R. Epelbaum, and M. Schaffer Curr. Med. Chem. 17 2010 190
6. D.K. Agrawal, and P.K. Mishra Med. Res. Rev. 30 2010 818
7. P. Basnet, and N. Skalko-Basnet Molecules 16 2011 4567
8. R.A. Sharma, W.P. Steward, and A.J. Gescher Adv. Exp. Med. Biol. 595 2007 453
9. P. Anand, A.B. Kunnumakkara, and R.A. Newman Mol. Pharmacol. 4 2007 807
10. R.A. Sharma, A.J. Gescher, and W.P. Steward Eur. J. Cancer 41 2005 1955
11. M.H. Pan, T.M. Huang, and J.K. Lin Drug Metab. Dispos. 27 1999 486
12. C. Ireson, S. Orr, and D.J. Jones Cancer Res. 61 2001 1058
13. V. Ravindranath, and N. Chandrasekhara Toxicology 20 1981 251
14. G.D. Straganz, A. Glieder, and L. Brecker Biochem. J. 369 2003 573
15. M.J. Rosemond, L. St. John-Williams, T. Yamaguchi, T. Fujishita, and J.S. Walsh Chem. Biol. Interact. 147 2004 129
16. G. Grogan Biochem. J. 388 2005 721
17. L. Li, F.S. Braiteh, and R. Kurzrock Cancer 104 2005 1322
18. G. Liang, S. Yang, and L. Jiang Chem. Pharm. Bull. 56 2008 162
19. G. Liang, L. Shao, and Y. Wang Bioorg. Med. Chem. 17 2009 2623
20. H. Yamakoshi, H. Ohori, and C. Kudo Bioorg. Med. Chem. 18 2010 1083
21. R.K. Singh, D. Rai, and D. Yadav Eur. J. Med. Chem. 45 2010 1078
22. U.S. Cancer Statistics Working Group. United States Cancer Statistics: 1999-2011 Incidence and Mortality Web-based Report U.S. Department of Health and Human Services, Centers for Disease Control and Prevention and National Cancer Institute: Atlanta, http://apps.nccd.cdc.gov/uscs/ (accessed 03/18/2015)
23. C.A. Higgins, Z. Delbederi, and K. McGarel Bioconjugate Chem. 20 2009 1737
24. J.B. Lambert, H.F. Shurvell, and D.A. Lightner Graham Cooks 1998 R. Organic Structural Spectroscopy; Prentice Hall New Jersey
25. S. Aggarwal, H. Ichikawa, and Y. Takada Mol. Pharmacol. 69 2006 195
26. S. Prakobwong, J. Khoontawad, and P. Yongvanit Int. J. Cancer 129 2011 88
27. Y. Yamamoto, and R.B. Gaynor J. Clin. Invest. 107 2001 135
28. S.T. Tharakan, T. Inamoto, and B. Sung Biochem. Pharmacol. 79 2010 218
29. K. Schutters, and C. Reutelingsperger Apoptosis 15 2010 1072
30. D. Wlodkowic, W. Telford, and J. Skommer Methods Cell Biol. 103 2011 55
31. A.H. Wyllie Mol. Neurobiol. 42 2010 4
32. G.N. Roth, A. Chandra, and M.G. Nair J. Nat. Prod. 61 1998 542
33. A.C. Ketron, O.N. Gordon, and C. Schneider Biochemistry 52 2013 221
34. A. Kumar, and U. Bora Interdisc. Sci. 6 2014 285
35. K. Suzuki, F. Shono, and H. Kai J. Enzyme Inhib. 15 2000 357
36. B.C. Giovanella, J.S. Stehlin, and M.E. Wall Science 246 1989 1046