Aging reduces the functionality of anti-pneumococcal antibodies and the killing of Streptococcus pneumoniae by neutrophil phagocytosis

Vaccine

Volumn 29, Issue 10, 2011, Pages 1929-1934

  Simell, Birgit ^a   Vuorela, Arja ^a   Ekström, Nina ^a   Palmu, Arto ^a   Reunanen, Antti ^a   Meri, Seppo ^b   Käyhty, Helena ^a   Väkeväinen, Merja ^a  

^a NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

Aging; Immune function; Pneumococcal

Indexed keywords

BACTERIUM ANTIBODY; PNEUMOCOCCAL ANTIBODY; UNCLASSIFIED DRUG;

ADAPTIVE IMMUNITY; ADULT; AGED; AGING; ANTIBODY SPECIFICITY; ARTICLE; BACTERICIDAL ACTIVITY; CELL FUNCTION; COMPLEMENT INHIBITION; CONTROLLED STUDY; DISEASE PREDISPOSITION; HUMAN; MAJOR CLINICAL STUDY; NEUTROPHIL; PHAGOCYTOSIS; PRIORITY JOURNAL; RISK FACTOR; SEROTYPE; STREPTOCOCCUS PNEUMONIAE;

ADOLESCENT; ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; AGING; ANTIBODIES, BACTERIAL; BLOOD BACTERICIDAL ACTIVITY; COMPLEMENT SYSTEM PROTEINS; FEMALE; HUMANS; MALE; MIDDLE AGED; NEUTROPHILS; OPSONIN PROTEINS; PHAGOCYTOSIS; STREPTOCOCCUS PNEUMONIAE; YOUNG ADULT;

EID: 79951722208     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2010.12.121     Document Type: Article

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