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Volumn 33, Issue 8, 2015, Pages 2550-2563

Chondroitin Sulfate Proteoglycans Negatively Modulate Spinal Cord Neural Precursor Cells by Signaling Through LAR and RPTPσ and Modulation of the Rho/ROCK Pathway

Author keywords

Adult neural precursor cells; Akt; Cell differentiation; Chondroitin sulfate proteoglycan; Erk1 2; Leukocyte common antigen related phosphatase; Receptor protein tyrosine phosphate sigma; Rho

Indexed keywords

LAMININ; LEUKOCYTE COMMON ANTIGEN RELATED PHOSPHATASE; MITOGEN ACTIVATED PROTEIN KINASE 3; PHOSPHATASE; PROTEIN KINASE B; PROTEIN TYROSINE PHOSPHATASE; PROTEOCHONDROITIN SULFATE; RECEPTOR PROTEIN TYROSINE PHOSPHATE SIGMA; RHO KINASE; UNCLASSIFIED DRUG; CHONDROITIN SULFATE; PROTEOGLYCAN; PTPRD PROTEIN, MOUSE; RECEPTOR LIKE PROTEIN TYROSINE PHOSPHATASE;

EID: 84937641747     PISSN: 10665099     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.1979     Document Type: Article
Times cited : (63)

References (75)
  • 1
    • 0029860591 scopus 로고    scopus 로고
    • Multipotent CNS stem cells are present in the adult mammalian spinal cord and ventricular neuroaxis
    • Weiss S, Dunne C, Hewson J, et al., Multipotent CNS stem cells are present in the adult mammalian spinal cord and ventricular neuroaxis. J Neurosci 1996; 16: 7599-7609.
    • (1996) J Neurosci , vol.16 , pp. 7599-7609
    • Weiss, S.1    Dunne, C.2    Hewson, J.3
  • 2
    • 0033534379 scopus 로고    scopus 로고
    • Identification of a neural stem cell in the adult mammalian central nervous system
    • Johansson CB, Momma S, Clarke DL, et al., Identification of a neural stem cell in the adult mammalian central nervous system. Cell 1999; 96: 25-34.
    • (1999) Cell , vol.96 , pp. 25-34
    • Johansson, C.B.1    Momma, S.2    Clarke, D.L.3
  • 3
    • 33645455547 scopus 로고    scopus 로고
    • Delayed transplantation of adult neural precursor cells promotes remyelination and functional neurological recovery after spinal cord injury
    • Karimi-Abdolrezaee S, Eftekharpour E, Wang J, et al., Delayed transplantation of adult neural precursor cells promotes remyelination and functional neurological recovery after spinal cord injury. J Neurosci 2006; 26: 3377-3389.
    • (2006) J Neurosci , vol.26 , pp. 3377-3389
    • Karimi-Abdolrezaee, S.1    Eftekharpour, E.2    Wang, J.3
  • 4
    • 76149105178 scopus 로고    scopus 로고
    • Synergistic effects of transplanted adult neural stem/progenitor cells, chondroitinase, and growth factors promote functional repair and plasticity of the chronically injured spinal Cord
    • Karimi-Abdolrezaee S, Eftekharpour E, Wang J, et al., Synergistic effects of transplanted adult neural stem/progenitor cells, chondroitinase, and growth factors promote functional repair and plasticity of the chronically injured spinal Cord. J Neurosci 2010; 30: 1657-1676.
    • (2010) J Neurosci , vol.30 , pp. 1657-1676
    • Karimi-Abdolrezaee, S.1    Eftekharpour, E.2    Wang, J.3
  • 5
    • 48349122033 scopus 로고    scopus 로고
    • Spinal cord injury reveals multilineage differentiation of ependymal cells
    • Meletis K, Barnabé-Heider F, Carlén M, et al., Spinal cord injury reveals multilineage differentiation of ependymal cells. PloS Biol 2008; 6.
    • (2008) PloS Biol , vol.6
    • Meletis, K.1    Barnabé-Heider, F.2    Carlén, M.3
  • 6
    • 77957331909 scopus 로고    scopus 로고
    • Origin of new glial cells in intact and injured adult spinal cord
    • Barnabé-Heider F, Göritz C, Sabelström H, et al., Origin of new glial cells in intact and injured adult spinal cord. Cell Stem Cell 2010; 7: 470-482.
    • (2010) Cell Stem Cell , vol.7 , pp. 470-482
    • Barnabé-Heider, F.1    Göritz, C.2    Sabelström, H.3
  • 7
    • 12844282237 scopus 로고    scopus 로고
    • Proliferation, migration, and differentiation of endogenous ependymal region stem/progenitor cells following minimal spinal cord injury in the adult rat
    • Mothe AJ, Tator CH,. Proliferation, migration, and differentiation of endogenous ependymal region stem/progenitor cells following minimal spinal cord injury in the adult rat. Neuroscience 2005; 131: 177.
    • (2005) Neuroscience , vol.131 , pp. 177
    • Mothe, A.J.1    Tator, C.H.2
  • 8
    • 84861327454 scopus 로고    scopus 로고
    • Chondroitinase and growth factors enhance activation and oligodendrocyte differentiation of endogenous neural precursor cells after spinal cord injury
    • Karimi-Abdolrezaee S, Schut D, Wang J, et al., Chondroitinase and growth factors enhance activation and oligodendrocyte differentiation of endogenous neural precursor cells after spinal cord injury. Plos One 2012; 7: 1-16.
    • (2012) Plos One , vol.7 , pp. 1-16
    • Karimi-Abdolrezaee, S.1    Schut, D.2    Wang, J.3
  • 9
    • 84868158857 scopus 로고    scopus 로고
    • Reactive Astrogliosis after Spinal Cord Injury-Beneficial and Detrimental Effects
    • Karimi-Abdolrezaee S, Billakanti R,. Reactive Astrogliosis after Spinal Cord Injury-Beneficial and Detrimental Effects. Mol Neurobiol. 2012.
    • (2012) Mol Neurobiol.
    • Karimi-Abdolrezaee, S.1    Billakanti, R.2
  • 10
    • 49049091210 scopus 로고    scopus 로고
    • STAT3 is a critical regulator of astrogliosis and scar formation after spinal cord injury
    • Herrmann JE, Imura T, Qi BJ, et al., STAT3 is a critical regulator of astrogliosis and scar formation after spinal cord injury. J Neurosci 2008; 28: 7231-7243.
    • (2008) J Neurosci , vol.28 , pp. 7231-7243
    • Herrmann, J.E.1    Imura, T.2    Qi, B.J.3
  • 11
    • 38649112309 scopus 로고    scopus 로고
    • CNS injury, glial scars, and inflammation: Inhibitory extracellular matrices and regeneration failure
    • Fitch MT, Silver J,. CNS injury, glial scars, and inflammation: Inhibitory extracellular matrices and regeneration failure. Exp Neurol 2008; 209: 294-301.
    • (2008) Exp Neurol , vol.209 , pp. 294-301
    • Fitch, M.T.1    Silver, J.2
  • 12
    • 84893346969 scopus 로고    scopus 로고
    • Awakening the stalled axon - Surprises in CSPG gradients
    • Lee SJ, Kalinski AL, Twiss JL,. Awakening the stalled axon-Surprises in CSPG gradients. Exp Neurol 2014; 254: 12-17.
    • (2014) Exp Neurol , vol.254 , pp. 12-17
    • Lee, S.J.1    Kalinski, A.L.2    Twiss, J.L.3
  • 13
    • 0037061426 scopus 로고    scopus 로고
    • Chondroitinase ABC promotes functional recovery after spinal cord injury
    • Bradbury EJ, Moon LDF, Popat RJ, et al., Chondroitinase ABC promotes functional recovery after spinal cord injury. Nature 2002; 416: 636-640.
    • (2002) Nature , vol.416 , pp. 636-640
    • Bradbury, E.J.1    Moon, L.D.F.2    Popat, R.J.3
  • 14
    • 33750932815 scopus 로고    scopus 로고
    • Chondroitinase ABC promotes sprouting of intact and injured spinal systems after spinal cord injury
    • Barritt AW, Davies M, Marchand F, et al., Chondroitinase ABC promotes sprouting of intact and injured spinal systems after spinal cord injury. J Neurosci 2006; 26.
    • (2006) J Neurosci , vol.26
    • Barritt, A.W.1    Davies, M.2    Marchand, F.3
  • 15
    • 33646442052 scopus 로고    scopus 로고
    • Chondroitinase ABC digestion of the perineuronal net promotes functional collateral sprouting in the cuneate nucleus after cervical spinal cord injury
    • Massey JM, Hubscher CH, Wagoner MR, et al., Chondroitinase ABC digestion of the perineuronal net promotes functional collateral sprouting in the cuneate nucleus after cervical spinal cord injury. J Neurosci 2006; 26: 4406-4414.
    • (2006) J Neurosci , vol.26 , pp. 4406-4414
    • Massey, J.M.1    Hubscher, C.H.2    Wagoner, M.R.3
  • 16
    • 79960405675 scopus 로고    scopus 로고
    • Functional regeneration of respiratory pathways after spinal cord injury
    • Alilain WJ, Horn KP, Hu H, et al., Functional regeneration of respiratory pathways after spinal cord injury. Nature 2011; 475: 196-200.
    • (2011) Nature , vol.475 , pp. 196-200
    • Alilain, W.J.1    Horn, K.P.2    Hu, H.3
  • 17
    • 38649124935 scopus 로고    scopus 로고
    • Increased chondroitin sulfate proteoglycan expression in denervated brainstem targets following spinal cord injury creates a barrier to axonal regeneration overcome by chondroitinase ABC and neurotrophin-3
    • Massey JM, Amps J, Viapiano MS, et al., Increased chondroitin sulfate proteoglycan expression in denervated brainstem targets following spinal cord injury creates a barrier to axonal regeneration overcome by chondroitinase ABC and neurotrophin-3. Exp Neurol 2008; 209: 426-445.
    • (2008) Exp Neurol , vol.209 , pp. 426-445
    • Massey, J.M.1    Amps, J.2    Viapiano, M.S.3
  • 18
    • 84874631221 scopus 로고    scopus 로고
    • Neutralization of inhibitory molecule NG2 improves synaptic transmission, retrograde transport, and locomotor function after spinal cord injury in adult rats
    • Petrosyan HA, Hunanyan AS, Alessi V, et al., Neutralization of inhibitory molecule NG2 improves synaptic transmission, retrograde transport, and locomotor function after spinal cord injury in adult rats. J Neurosci 2013; 33: 4032-4043.
    • (2013) J Neurosci , vol.33 , pp. 4032-4043
    • Petrosyan, H.A.1    Hunanyan, A.S.2    Alessi, V.3
  • 19
    • 62049083009 scopus 로고    scopus 로고
    • Chronic spinal hemisection in rats induces a progressive decline in transmission in uninjured fiber to motorneurons
    • Arvantan VI, Schnell I, Lou I, et al., Chronic spinal hemisection in rats induces a progressive decline in transmission in uninjured fiber to motorneurons. Exp Neurol 2009; 216: 471-480.
    • (2009) Exp Neurol , vol.216 , pp. 471-480
    • Arvantan, V.I.1    Schnell, I.2    Lou, I.3
  • 20
    • 77953505977 scopus 로고    scopus 로고
    • Role of chondroitin sulfate proteoglycans in axonal conduction in Mammalian spinal cord
    • Hunanyan AS, García-Alías G, Alessi V, et al., Role of chondroitin sulfate proteoglycans in axonal conduction in Mammalian spinal cord. J Neurosci 2010; 30: 7761.
    • (2010) J Neurosci , vol.30 , pp. 7761
    • Hunanyan, A.S.1    García-Alías, G.2    Alessi, V.3
  • 21
    • 84908565781 scopus 로고    scopus 로고
    • Examination of the combined effects of chondroitinase ABC, growth factors and locomotor training following compressive spinal cord injury on neuroanatomical plasticity and kinematics
    • Alluin O, Delivet-Mongrain H, Gauthier MK, et al., Examination of the combined effects of chondroitinase ABC, growth factors and locomotor training following compressive spinal cord injury on neuroanatomical plasticity and kinematics. PLoS One 2014; 9: e111072.
    • (2014) PLoS One , vol.9 , pp. e111072
    • Alluin, O.1    Delivet-Mongrain, H.2    Gauthier, M.K.3
  • 22
    • 29344451629 scopus 로고    scopus 로고
    • Chondroitinase ABC combined with neural stem/progenitor cell transplantation enhances graft cell migration and outgrowth of growth-associated protein-43-positive fibers after rat spinal cord injury
    • Ikegami T, Nakamura M, Yamane J, et al., Chondroitinase ABC combined with neural stem/progenitor cell transplantation enhances graft cell migration and outgrowth of growth-associated protein-43-positive fibers after rat spinal cord injury. Eur J Neurosci 2005; 22: 3036-3046.
    • (2005) Eur J Neurosci , vol.22 , pp. 3036-3046
    • Ikegami, T.1    Nakamura, M.2    Yamane, J.3
  • 23
    • 70350502060 scopus 로고    scopus 로고
    • PTPσ is a receptor for chondroitin sulfate proteoglycan, an inhibitor of neural regeneration
    • Shen Y, Tenney AP, Busch SA, et al., PTPσ is a receptor for chondroitin sulfate proteoglycan, an inhibitor of neural regeneration. Science 2009; 326: 592-596.
    • (2009) Science , vol.326 , pp. 592-596
    • Shen, Y.1    Tenney, A.P.2    Busch, S.A.3
  • 24
    • 80053624921 scopus 로고    scopus 로고
    • Leukocyte common antigen-related phosphatase is a functional receptor for chondroitin sulfate proteoglycan axon growth inhibitors
    • Fisher D, Xing B, Dill J, et al., Leukocyte common antigen-related phosphatase is a functional receptor for chondroitin sulfate proteoglycan axon growth inhibitors. J Neurosci 2011; 31: 14051-14066.
    • (2011) J Neurosci , vol.31 , pp. 14051-14066
    • Fisher, D.1    Xing, B.2    Dill, J.3
  • 25
    • 0032979722 scopus 로고    scopus 로고
    • Neuroendocrine dysplasia in mice lacking protein tyrosine phosphatase σ
    • Elchebly M, Wagner J, Kennedy TE, et al., Neuroendocrine dysplasia in mice lacking protein tyrosine phosphatase σ. Nat Genet 1999; 21: 330-334.
    • (1999) Nat Genet , vol.21 , pp. 330-334
    • Elchebly, M.1    Wagner, J.2    Kennedy, T.E.3
  • 26
    • 84883461842 scopus 로고    scopus 로고
    • Dysregulation of the neuregulin-1-ErbB network modulates endogenous oligodendrocyte differentiation and preservation after spinal cord injury
    • Gauthier M-K, Kosciuczyk K, Tapley L, et al., Dysregulation of the neuregulin-1-ErbB network modulates endogenous oligodendrocyte differentiation and preservation after spinal cord injury. Eur J Neurosci 2013; 38: 2693-2715.
    • (2013) Eur J Neurosci , vol.38 , pp. 2693-2715
    • Gauthier, M.-K.1    Kosciuczyk, K.2    Tapley, L.3
  • 27
    • 68949212366 scopus 로고    scopus 로고
    • NG2 and phosphacan are present in the astroglial scar after human traumatic spinal cord injury
    • Buss A, Pech K, Kakulas BA, et al., NG2 and phosphacan are present in the astroglial scar after human traumatic spinal cord injury. BMC Neurol 2009; 9.
    • (2009) BMC Neurol , vol.9
    • Buss, A.1    Pech, K.2    Kakulas, B.A.3
  • 28
    • 33947645277 scopus 로고    scopus 로고
    • The role of chondroitin sulfate proteoglycans in regeneration and plasticity in the central nervous system
    • Galtrey CM, Fawcett JW,. The role of chondroitin sulfate proteoglycans in regeneration and plasticity in the central nervous system. Brain Res Rev 2007; 54: 1.
    • (2007) Brain Res Rev , vol.54 , pp. 1
    • Galtrey, C.M.1    Fawcett, J.W.2
  • 29
    • 0032728370 scopus 로고    scopus 로고
    • Chondroitin sulfate proteoglycan immunoreactivity increases following spinal cord injury and transplantation
    • Lemons ML, Howland DR, Anderson DK,. Chondroitin sulfate proteoglycan immunoreactivity increases following spinal cord injury and transplantation. Exp Neurol 1999; 160: 51-65.
    • (1999) Exp Neurol , vol.160 , pp. 51-65
    • Lemons, M.L.1    Howland, D.R.2    Anderson, D.K.3
  • 30
    • 84900514368 scopus 로고    scopus 로고
    • Remyelination after spinal cord injury: Is it a target for repair?
    • Plemel JR, Keough MB, Duncan GJ, et al., Remyelination after spinal cord injury: Is it a target for repair? Prog Neurobiol 2014; 117: 54-72.
    • (2014) Prog Neurobiol , vol.117 , pp. 54-72
    • Plemel, J.R.1    Keough, M.B.2    Duncan, G.J.3
  • 31
    • 79955470793 scopus 로고    scopus 로고
    • Proteoglycan-specific molecular switch for RPTPσ clustering and neuronal extension
    • Coles CH, Shen Y, Tenney AP, et al., Proteoglycan-specific molecular switch for RPTPσ clustering and neuronal extension. Science 2011; 332.
    • (2011) Science , vol.332
    • Coles, C.H.1    Shen, Y.2    Tenney, A.P.3
  • 32
    • 76549086557 scopus 로고    scopus 로고
    • Corticospinal tract regeneration after spinal cord injury in receptor protein tyrosine phosphatase sigma deficient mice
    • Fry EJ, Chagnon MJ, Lõpez-Vales R, et al., Corticospinal tract regeneration after spinal cord injury in receptor protein tyrosine phosphatase sigma deficient mice. Glia 2010; 58: 423-433.
    • (2010) Glia , vol.58 , pp. 423-433
    • Fry, E.J.1    Chagnon, M.J.2    Lõpez-Vales, R.3
  • 33
    • 0034678363 scopus 로고    scopus 로고
    • Ephrin-A5 induces collapse of growth cones by activating Rho and Rho kinase
    • Wahl S, Barth H, Ciossek T, et al., Ephrin-A5 induces collapse of growth cones by activating Rho and Rho kinase. J Cell Biol 2000; 149: 263-270.
    • (2000) J Cell Biol , vol.149 , pp. 263-270
    • Wahl, S.1    Barth, H.2    Ciossek, T.3
  • 34
    • 0037356722 scopus 로고    scopus 로고
    • The Rho/+ROCK pathway mediates neurite growth-inhibitory activity associated with the chondroitin sulfate proteoglycans of the CNS glial scar
    • Monnier PP, Sierra A, Schwab JM, et al., The Rho/+ROCK pathway mediates neurite growth-inhibitory activity associated with the chondroitin sulfate proteoglycans of the CNS glial scar. Mol Cell Neurosci 2003; 22: 319-330.
    • (2003) Mol Cell Neurosci , vol.22 , pp. 319-330
    • Monnier, P.P.1    Sierra, A.2    Schwab, J.M.3
  • 35
    • 84867247848 scopus 로고    scopus 로고
    • Intra-axonal translation of RhoA promotes axon growth inhibition by CSPG
    • Walker BA, Ji S-J, Jaffrey SR,. Intra-axonal translation of RhoA promotes axon growth inhibition by CSPG. J Neurosci 2012; 32: 14442-14447.
    • (2012) J Neurosci , vol.32 , pp. 14442-14447
    • Walker, B.A.1    Ji, S.-J.2    Jaffrey, S.R.3
  • 36
    • 84877804122 scopus 로고    scopus 로고
    • Chondroitin sulfate proteoglycans inhibit oligodendrocyte myelination through PTPσ
    • Pendleton JC, Shamblott MJ, Gary DS, et al., Chondroitin sulfate proteoglycans inhibit oligodendrocyte myelination through PTPσ. Exp Neurol 2013; 247: 113-121.
    • (2013) Exp Neurol , vol.247 , pp. 113-121
    • Pendleton, J.C.1    Shamblott, M.J.2    Gary, D.S.3
  • 37
    • 0037443069 scopus 로고    scopus 로고
    • Rho kinase inhibition enhances axonal regeneration in the injury CNS
    • Fournier AE, Takizawa BT, Strittmatter SM,. Rho kinase inhibition enhances axonal regeneration in the injury CNS. J Neurosci 2003; 24: 1416-1423.
    • (2003) J Neurosci , vol.24 , pp. 1416-1423
    • Fournier, A.E.1    Takizawa, B.T.2    Strittmatter, S.M.3
  • 38
    • 84862900786 scopus 로고    scopus 로고
    • ERK1/ERK2 MAPK signaling is required to increase myelin thickness independent of oligodendrocyte differentiation and initiation of myelination
    • Ashii A, Fyffe-Marcich SL, Furusho M, et al., ERK1/ERK2 MAPK signaling is required to increase myelin thickness independent of oligodendrocyte differentiation and initiation of myelination. J Neurosci 2012; 32: 8855-8864.
    • (2012) J Neurosci , vol.32 , pp. 8855-8864
    • Ashii, A.1    Fyffe-Marcich, S.L.2    Furusho, M.3
  • 39
    • 78751509692 scopus 로고    scopus 로고
    • The ERK2 mitogen-activated protein kinase regulates the timing of oligodendrocyte differentiation
    • Fyffe-Maricich SL, Karlo JC, Landreth GE, et al., The ERK2 mitogen-activated protein kinase regulates the timing of oligodendrocyte differentiation. J Neurosci 2011; 31: 843-850.
    • (2011) J Neurosci , vol.31 , pp. 843-850
    • Fyffe-Maricich, S.L.1    Karlo, J.C.2    Landreth, G.E.3
  • 40
    • 84856208745 scopus 로고    scopus 로고
    • Erk1/2 MAPK and mTOR signaling sequentially regulates progression through distinct stages of oligodendrocyte differentiation
    • Guardiola-Diaz HM, Ishii A, Bansal R,. Erk1/2 MAPK and mTOR signaling sequentially regulates progression through distinct stages of oligodendrocyte differentiation. Glia 2012; 60: 476-486.
    • (2012) Glia , vol.60 , pp. 476-486
    • Guardiola-Diaz, H.M.1    Ishii, A.2    Bansal, R.3
  • 42
    • 79960832807 scopus 로고    scopus 로고
    • A systematic review of cellular transplantation therapies for spinal cord injury
    • Tetzlaff W, Okon E, Karimi-Abdolrezaee S, et al., A systematic review of cellular transplantation therapies for spinal cord injury. J Neurotrauma 2011; 28: 1611-1682.
    • (2011) J Neurotrauma , vol.28 , pp. 1611-1682
    • Tetzlaff, W.1    Okon, E.2    Karimi-Abdolrezaee, S.3
  • 44
    • 20044370811 scopus 로고    scopus 로고
    • Allodynia limits the usefullness of intraspinal neural stem cells grafts; Directed differentiation imrpoves outcome
    • Hofstetter C, Holmström N, Lilja J, et al., Allodynia limits the usefullness of intraspinal neural stem cells grafts; directed differentiation imrpoves outcome. Nat Neurosci 2005; 8: 346-353.
    • (2005) Nat Neurosci , vol.8 , pp. 346-353
    • Hofstetter, C.1    Holmström, N.2    Lilja, J.3
  • 45
    • 49249125590 scopus 로고    scopus 로고
    • Fate of transplanted adult neural stem/progenitor cells and bone marrow-derived mesenchymal stromal cells in the injured adult rat spinal cord and impact on functional recovery
    • Parr A, Kulbatski I, Wang X, et al., Fate of transplanted adult neural stem/progenitor cells and bone marrow-derived mesenchymal stromal cells in the injured adult rat spinal cord and impact on functional recovery. Surg Neurol 2008; 70: 600-607.
    • (2008) Surg Neurol , vol.70 , pp. 600-607
    • Parr, A.1    Kulbatski, I.2    Wang, X.3
  • 46
    • 33748358798 scopus 로고    scopus 로고
    • Synergy between immune cells and adult neural stem/progenitor cells promotes functional recovery from spinal cord injury
    • Ziv Y, Avidan J, Pluchino S, et al., Synergy between immune cells and adult neural stem/progenitor cells promotes functional recovery from spinal cord injury. PNAS 2006; 103: 13174-13179.
    • (2006) PNAS , vol.103 , pp. 13174-13179
    • Ziv, Y.1    Avidan, J.2    Pluchino, S.3
  • 47
    • 84867064116 scopus 로고    scopus 로고
    • Chondroitin sulfate proteoglycans in demyelinated lesions impair remyelination
    • Lau LW, Keough MB, Haylock-Jacobs S, et al., Chondroitin sulfate proteoglycans in demyelinated lesions impair remyelination. Ann Neurol 2012; 72: 419-432.
    • (2012) Ann Neurol , vol.72 , pp. 419-432
    • Lau, L.W.1    Keough, M.B.2    Haylock-Jacobs, S.3
  • 48
    • 0346749451 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9 facilitates remyelination in part by processing the inhibitory NG2 proteoglycan
    • Larsen PH, Wells JE, Stallcup WB, et al., Matrix metalloproteinase-9 facilitates remyelination in part by processing the inhibitory NG2 proteoglycan. J Neurosci 2003; 23: 11135-11127.
    • (2003) J Neurosci , vol.23 , pp. 11135-11127
    • Larsen, P.H.1    Wells, J.E.2    Stallcup, W.B.3
  • 49
    • 84887293716 scopus 로고    scopus 로고
    • Resident neural stem cells restrict tissue damage and neuronal loss after spinal cord injury in mice
    • Sabelström H, Stenudd M, Réu P, et al., Resident neural stem cells restrict tissue damage and neuronal loss after spinal cord injury in mice. Science 2013; 342: 637-640.
    • (2013) Science , vol.342 , pp. 637-640
    • Sabelström, H.1    Stenudd, M.2    Réu, P.3
  • 50
    • 84860284042 scopus 로고    scopus 로고
    • NgR1 and NgR3 are receptors for chondroitin sulfate proteoglycans
    • Dickendesher TL, Mironova KTBYA, Koriyama Y, et al., NgR1 and NgR3 are receptors for chondroitin sulfate proteoglycans. Nat Neurosci 2012; 15: 703-712.
    • (2012) Nat Neurosci , vol.15 , pp. 703-712
    • Dickendesher, T.L.1    Mironova, K.2    Koriyama, Y.3
  • 51
    • 0036663073 scopus 로고    scopus 로고
    • Enhanced rate of nerve regeneration and directional errors after sciatic nerve injury in receptor protein tyrosine phosphatase σ knock-out mice
    • McLean J, Batt J, Doering LC, et al., Enhanced rate of nerve regeneration and directional errors after sciatic nerve injury in receptor protein tyrosine phosphatase σ knock-out mice. J Neurosci 2002; 22: 5481-5491.
    • (2002) J Neurosci , vol.22 , pp. 5481-5491
    • McLean, J.1    Batt, J.2    Doering, L.C.3
  • 52
    • 0042661165 scopus 로고    scopus 로고
    • Receptor protein tyrosine phosphatase sigma inhibits axonal regeneration and the rate of axon extension
    • Thompson KM, Uetani N, Manitt C, et al., Receptor protein tyrosine phosphatase sigma inhibits axonal regeneration and the rate of axon extension. Mol Cell Neurosci 2003; 24: 681-692.
    • (2003) Mol Cell Neurosci , vol.24 , pp. 681-692
    • Thompson, K.M.1    Uetani, N.2    Manitt, C.3
  • 53
    • 15244360337 scopus 로고    scopus 로고
    • Receptor protein tyrosine phosphatase sigma inhibits axon regrowth in the adult injured CNS
    • Sapeiha PS, Duplan L, Ietani N, et al., Receptor protein tyrosine phosphatase sigma inhibits axon regrowth in the adult injured CNS. Mol Cell Neurosci 2005; 28: 353-359.
    • (2005) Mol Cell Neurosci , vol.28 , pp. 353-359
    • Sapeiha, P.S.1    Duplan, L.2    Ietani, N.3
  • 54
    • 33748906638 scopus 로고    scopus 로고
    • Neural stem cells from protein tyrosine phosphatase sigma knockout mice generate an altered neuronal phenotype in culture
    • Kirkham DL, Pacey LK, Axford MM, et al., Neural stem cells from protein tyrosine phosphatase sigma knockout mice generate an altered neuronal phenotype in culture. BMC Neurosci 2006; 7: 1-9.
    • (2006) BMC Neurosci , vol.7 , pp. 1-9
    • Kirkham, D.L.1    Pacey, L.K.2    Axford, M.M.3
  • 55
    • 84860365486 scopus 로고    scopus 로고
    • The roles of neuronal and glial precursors in overcoming chondroitin sulfate proteoglycan inhibition
    • Ketschek AR, Haas C, Gallo G, et al., The roles of neuronal and glial precursors in overcoming chondroitin sulfate proteoglycan inhibition. Exp Neurol 2012; 235: 627-637.
    • (2012) Exp Neurol , vol.235 , pp. 627-637
    • Ketschek, A.R.1    Haas, C.2    Gallo, G.3
  • 56
    • 33746895084 scopus 로고    scopus 로고
    • Neurotrophins support regenerative axon assembly over CSPGs by an ECM-integrin-independent mechanism
    • Zhou FQ, Walzer M, Wu YH, et al., Neurotrophins support regenerative axon assembly over CSPGs by an ECM-integrin-independent mechanism. J Cell Sci 2006; 119: 2787-2796.
    • (2006) J Cell Sci , vol.119 , pp. 2787-2796
    • Zhou, F.Q.1    Walzer, M.2    Wu, Y.H.3
  • 57
    • 0032527889 scopus 로고    scopus 로고
    • Neuronal matrix metalloproteinase-2 degrades and inactivates a neurite-inhibiting chondroint sulfate proteoglycan
    • Zuo J, Ferguson TA, Hernandez YJ, et al., Neuronal matrix metalloproteinase-2 degrades and inactivates a neurite-inhibiting chondroint sulfate proteoglycan. J Neurosci 1998; 18: 5203-5211.
    • (1998) J Neurosci , vol.18 , pp. 5203-5211
    • Zuo, J.1    Ferguson, T.A.2    Hernandez, Y.J.3
  • 58
    • 84870989006 scopus 로고    scopus 로고
    • Perisynaptic Chondroitin sulfate proteoglycans restrict structural plasticity in an integrin-dependent manner
    • Orlando C, Ster J, Gerber U, et al., Perisynaptic Chondroitin sulfate proteoglycans restrict structural plasticity in an integrin-dependent manner. J Neurosci 2012; 32: 18009-18017.
    • (2012) J Neurosci , vol.32 , pp. 18009-18017
    • Orlando, C.1    Ster, J.2    Gerber, U.3
  • 59
    • 79955766629 scopus 로고    scopus 로고
    • Integrin activation promotes axon growth on inhibitory chondroitin sulfate proteoglycans by enhancing integrin signaling
    • Tan CL, Kwok JCF, Patani R, et al., Integrin activation promotes axon growth on inhibitory chondroitin sulfate proteoglycans by enhancing integrin signaling. J Neurosci 2011; 33: 6289-6295.
    • (2011) J Neurosci , vol.33 , pp. 6289-6295
    • Tan, C.L.1    Kwok, J.C.F.2    Patani, R.3
  • 60
    • 0042171820 scopus 로고    scopus 로고
    • Rho activation patterns after spinal cord injury and the role of activated Rho in apoptosis in the central nervous system
    • Dubreuil CI, Winton MJ, McKerracher L,. Rho activation patterns after spinal cord injury and the role of activated Rho in apoptosis in the central nervous system. J Cell Biol 2003; 162: 233-243.
    • (2003) J Cell Biol , vol.162 , pp. 233-243
    • Dubreuil, C.I.1    Winton, M.J.2    McKerracher, L.3
  • 61
    • 19544378707 scopus 로고    scopus 로고
    • Prolonged lesional expression of RhoA and RhoB following spinal cord injury
    • Conrad S, Schluesener HJ, Trautmann K, et al., Prolonged lesional expression of RhoA and RhoB following spinal cord injury. J Comp Neurol 2005; 487: 166-175.
    • (2005) J Comp Neurol , vol.487 , pp. 166-175
    • Conrad, S.1    Schluesener, H.J.2    Trautmann, K.3
  • 62
    • 0033529620 scopus 로고    scopus 로고
    • Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase
    • Maekawa M, Ishizaki T, Boku S, et al., Signaling from Rho to the actin cytoskeleton through protein kinases ROCK and LIM-kinase. Science 1999; 285: 895-898.
    • (1999) Science , vol.285 , pp. 895-898
    • Maekawa, M.1    Ishizaki, T.2    Boku, S.3
  • 63
    • 80052677773 scopus 로고    scopus 로고
    • The inhibitory effects of chondroitin sulfate proteoglycann on oligodendrocytes
    • Siebert J, Osterhout D,. The inhibitory effects of chondroitin sulfate proteoglycann on oligodendrocytes. J Neurochem 2011; 119: 176-188.
    • (2011) J Neurochem , vol.119 , pp. 176-188
    • Siebert, J.1    Osterhout, D.2
  • 64
    • 0036895744 scopus 로고    scopus 로고
    • Nogo-A and myelin-associated glycoprotein mediate neurite growth inhibition by antagonistic regulation of RhoA and Rac1
    • Niederöst B, Oertle T, Fritsche J, et al., Nogo-A and myelin-associated glycoprotein mediate neurite growth inhibition by antagonistic regulation of RhoA and Rac1. J Neurosci 2002; 22: 10368-10378.
    • (2002) J Neurosci , vol.22 , pp. 10368-10378
    • Niederöst, B.1    Oertle, T.2    Fritsche, J.3
  • 65
    • 57349179914 scopus 로고    scopus 로고
    • Local inhibition of Rho signaling by cell-permeable recombinant protein Ba-210 prevents secondary damage and promotes functional recovery following acute spinal cord injury
    • Lord-Fontaine S, Yang F, Diep Q, et al., Local inhibition of Rho signaling by cell-permeable recombinant protein Ba-210 prevents secondary damage and promotes functional recovery following acute spinal cord injury. J Neurotrauma 2008; 25: 1309-1322.
    • (2008) J Neurotrauma , vol.25 , pp. 1309-1322
    • Lord-Fontaine, S.1    Yang, F.2    Diep, Q.3
  • 66
    • 79955961172 scopus 로고    scopus 로고
    • A phase I/IIa clinical trial of recombinant rho protein antagonist in acute spinal cord injury
    • Fehlings MG, Theodore N, Harrop J, et al., A phase I/IIa clinical trial of recombinant rho protein antagonist in acute spinal cord injury. J Neurotrauma 2011; 28: 787-796.
    • (2011) J Neurotrauma , vol.28 , pp. 787-796
    • Fehlings, M.G.1    Theodore, N.2    Harrop, J.3
  • 67
    • 84979851020 scopus 로고    scopus 로고
    • Differential regulation of proliferation and neuronal differentiation in adult rat spinal cord neuronal differentiation in adult rat spinal cord neural stem/progenitors by ERK1/2, Akt, and PLCγ
    • Chan WS, Sideris A, Sutachan JJ, et al., Differential regulation of proliferation and neuronal differentiation in adult rat spinal cord neuronal differentiation in adult rat spinal cord neural stem/progenitors by ERK1/2, Akt, and PLCγ. Front Mol Neurosci 2013; 6: 1-14.
    • (2013) Front Mol Neurosci , vol.6 , pp. 1-14
    • Chan, W.S.1    Sideris, A.2    Sutachan, J.J.3
  • 68
    • 0034667559 scopus 로고    scopus 로고
    • Akt-mediated survival of oligodendrocytes induced by neuregulin
    • Flores AI, Mallon BS, Matsui T, et al., Akt-mediated survival of oligodendrocytes induced by neuregulin. J Neurosci 2000; 20: 7622-7630.
    • (2000) J Neurosci , vol.20 , pp. 7622-7630
    • Flores, A.I.1    Mallon, B.S.2    Matsui, T.3
  • 69
    • 84878584955 scopus 로고    scopus 로고
    • Expansion of oligodendrocyte progenitor cells following SIRT1 inactivation in the adult brain
    • Rafalski VA, Ho PP, Brett JO, et al., Expansion of oligodendrocyte progenitor cells following SIRT1 inactivation in the adult brain. Nat Cell Biol 2013; 15: 614-624.
    • (2013) Nat Cell Biol , vol.15 , pp. 614-624
    • Rafalski, V.A.1    Ho, P.P.2    Brett, J.O.3
  • 70
    • 84856726620 scopus 로고    scopus 로고
    • Human umbilical cord blood cells protect oligodendrocytes from brain ischemia through Akt signal tranduction
    • Rowe DD, Leonardo CC, Recio JA, et al., Human umbilical cord blood cells protect oligodendrocytes from brain ischemia through Akt signal tranduction. J Biol Chem 2012; 287: 4177-4187.
    • (2012) J Biol Chem , vol.287 , pp. 4177-4187
    • Rowe, D.D.1    Leonardo, C.C.2    Recio, J.A.3
  • 71
    • 66049119030 scopus 로고    scopus 로고
    • Activation of the mammalian target of rapamycin (mTOR) is essential for oligodendrocyte differentiation
    • Tyler WA, Gangoli N, Gokina P, et al., Activation of the mammalian target of rapamycin (mTOR) is essential for oligodendrocyte differentiation. J Neurosci 2009; 29: 6367-6378.
    • (2009) J Neurosci , vol.29 , pp. 6367-6378
    • Tyler, W.A.1    Gangoli, N.2    Gokina, P.3
  • 72
    • 49049095578 scopus 로고    scopus 로고
    • Constitutively active Akt induces enhanced myelination in the CNS
    • Flores AI, Narayanan P, Morse EN, et al., Constitutively active Akt induces enhanced myelination in the CNS. J Neurosci 2008; 28: 7174-7183.
    • (2008) J Neurosci , vol.28 , pp. 7174-7183
    • Flores, A.I.1    Narayanan, P.2    Morse, E.N.3
  • 73
    • 77954391902 scopus 로고    scopus 로고
    • Elevated phosphatidylinositol 3,4,5-trisphosphate in glia triggers cell-autonomous membrane wrapping and myelination
    • Goebbels S, Oltrogge JH, Kemper R, et al., Elevated phosphatidylinositol 3,4,5-trisphosphate in glia triggers cell-autonomous membrane wrapping and myelination. J Neurosci 2010; 30: 8953-8964.
    • (2010) J Neurosci , vol.30 , pp. 8953-8964
    • Goebbels, S.1    Oltrogge, J.H.2    Kemper, R.3
  • 74
    • 84860701934 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor signaling in oligodendrocytes regulates myelin sheath thickness
    • Furusho M, Dupree JL, Nave K-A, et al., Fibroblast growth factor receptor signaling in oligodendrocytes regulates myelin sheath thickness. J Neurosci 2012; 32: 6631-6641.
    • (2012) J Neurosci , vol.32 , pp. 6631-6641
    • Furusho, M.1    Dupree, J.L.2    Nave, K.-A.3
  • 75
    • 78751509692 scopus 로고    scopus 로고
    • The ERK2 mitogen-activated protein kinase regulates the timing of oligodendrocyte differentiation
    • Fyffe-Maricich SI, Karlo JC, Landreth GE, et al., The ERK2 mitogen-activated protein kinase regulates the timing of oligodendrocyte differentiation. J Neurosci 2011; 31: 843-850.
    • (2011) J Neurosci , vol.31 , pp. 843-850
    • Fyffe-Maricich, S.I.1    Karlo, J.C.2    Landreth, G.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.