Human iPSC-Derived Neural Progenitors Preserve Vision in an AMD-Like Model

Stem Cells

Volumn 33, Issue 8, 2015, Pages 2537-2549

  Tsai, Yuchun ^a   Lu, Bin ^a   Bakondi, Benjamin ^a   Girman, Sergey ^a   Sahabian, Anais ^a   Sareen, Dhruv ^a   Svendsen, Clive N ^a   Wang, Shaomei ^a  

^a CEDARS SINAI MEDICAL CENTER   (United States)

Author keywords

Clinical translation; Induced pluripotent stem cells; Progenitor cells; Retinal degeneration; Stem cell transplantation

Indexed keywords

CALBINDIN 1; CYCLOSPORIN A; DEXAMETHASONE; FLUORESCEIN ISOTHIOCYANATE; PROTEIN KINASE C; RECOVERIN; RHODOPSIN; SYNAPTOPHYSIN;

AGE RELATED MACULAR DEGENERATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY LABELING; ARTICLE; BASEMENT MEMBRANE; CELL SURVIVAL; CELLULAR DISTRIBUTION; COMPARATIVE STUDY; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DISEASE COURSE; ELECTROPHYSIOLOGICAL PROCEDURES; ELECTRORETINOGRAPHY; FLOW CYTOMETRY; GRAFT SURVIVAL; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; INTERNALIZATION; NERVE ENDING; NEURAL STEM CELL; NEURAL STEM CELL TRANSPLANTATION; NONHUMAN; PHAGOCYTOSIS; PHAGOSOME; PHENOTYPE; PHOTORECEPTOR; PHOTORECEPTOR OUTER SEGMENT; PHOTOSTIMULATION; PLURIPOTENT STEM CELL; RAT; RETINA DEGENERATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SHAM PROCEDURE; TRANSMISSION ELECTRON MICROSCOPY; TREATMENT DURATION; VISION; VISUAL ACUITY; VISUAL IMPAIRMENT; WESTERN BLOTTING; ANIMAL; DISEASE MODEL; INDUCED PLURIPOTENT STEM CELL; MACULAR DEGENERATION; METABOLISM; PATHOLOGY; STEM CELL TRANSPLANTATION; TRANSPLANTATION;

RATTUS;

ANIMALS; DISEASE MODELS, ANIMAL; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MACULAR DEGENERATION; NEURAL STEM CELLS; RATS; STEM CELL TRANSPLANTATION; VISION, OCULAR;

EID: 84937640335     PISSN: 10665099     EISSN: 15494918     Source Type: Journal    
DOI: 10.1002/stem.2032     Document Type: Article

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