Lumbar intraspinal injection of neural stem cells in patients with amyotrophic lateral sclerosis: Results of a phase I trial in 12 patients

Stem Cells

Volumn 30, Issue 6, 2012, Pages 1144-1151

  Glass, Jonathan D ^a   Boulis, Nicholas M ^a   Johe, Karl ^b   Rutkove, Seward B ^c   Federici, Thais ^a   Polak, Meraida ^a   Kelly, Crystal ^a   Feldman, Eva L ^d  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Neuralstem Inc   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Amyotrophic lateral sclerosis; Clinical trial; Motor neuron disease; Spinal cord; Stem cells

Indexed keywords

ANTACID AGENT; ANTIDIARRHEAL AGENT; BASILIXIMAB; METHYLPREDNISOLONE; MYCOPHENOLIC ACID; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; NARCOTIC AGENT; PREDNISONE; TACROLIMUS;

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; BLOATING; BRAIN DISEASE; BRONCHITIS; CERVICAL SPINAL CORD; CHRONIC DIARRHEA; CLINICAL ARTICLE; CLINICAL ASSESSMENT; DIARRHEA; DISEASE COURSE; DRUG DOSE REDUCTION; DRUG WITHDRAWAL; DYSPNEA; FETUS CELL; FISTULA; GASTROINTESTINAL SYMPTOM; HEART ARRHYTHMIA; HEART VENTRICLE HYPERTROPHY; HUMAN; HUMAN CELL; LIQUORRHEA; LUMBAR SPINAL CORD; LUNG EMBOLISM; MALE; MORTALITY; MOTONEURON; NEURAL STEM CELL TRANSPLANTATION; PAIN; PHASE 1 CLINICAL TRIAL; PNEUMONIA; RESPIRATORY FAILURE; SAFETY; SENSORY DYSFUNCTION; TREATMENT OUTCOME; VOMITING; WOUND DEHISCENCE;

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; DISEASE PROGRESSION; HUMANS; INJECTIONS, SPINAL; LUMBOSACRAL REGION; MALE; MIDDLE AGED; NEURAL STEM CELLS; SPINAL CORD; STEM CELL TRANSPLANTATION; TREATMENT OUTCOME;

EID: 84861919329     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.1079     Document Type: Article

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