Retinal microenvironment imbalance in dry age-related macular degeneration: A mini-review

Gerontology

Volumn 59, Issue 4, 2013, Pages 297-306

  Barnett, Brad P ^a   Handa, James T ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

Author keywords

Age related macular degeneration; Aging; Complement; Innate immunity; Oxidation specific epitopes; Oxidative stress

Indexed keywords

ANATOMICAL CONCEPTS; ANTIOXIDANT ACTIVITY; CLINICAL FEATURE; COMPLEMENT DISORDER; EPIDEMIOLOGICAL DATA; HISTOLOGY; HUMAN; IMMUNE RESPONSE; INNATE IMMUNITY; MEDICAL LITERATURE; MICROENVIRONMENT; OXIDATION; OXIDATIVE STRESS; PATHOGENESIS; PRIORITY JOURNAL; RETINA MACULA AGE RELATED DEGENERATION; REVIEW; RISK ASSESSMENT; SMOKING; AGE RELATED MACULAR DEGENERATION; ANTIOXIDANT RESPONSIVE ELEMENT; APOPTOSIS; CHRONIC INFLAMMATION; COMPLEMENT ACTIVATION; COMPLEMENT ALTERNATIVE PATHWAY; COMPLEMENT SYSTEM; EYE INFLAMMATION; PHOTORECEPTOR; PHOTORECEPTOR OUTER SEGMENT; PIGMENT EPITHELIUM; RETINA; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; VISUAL IMPAIRMENT;

AGING; ANIMALS; DNA DAMAGE; DNA, MITOCHONDRIAL; HUMANS; IMMUNITY, INNATE; MACULAR DEGENERATION; MICE; OXIDATIVE STRESS; POLYMORPHISM, GENETIC; RETINA; RETINAL PIGMENT EPITHELIUM; RISK FACTORS; SMOKING;

ANTIOXIDANT; BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR; CIGARETTE SMOKE; COMPLEMENT; CYTOKINE; EPITOPE; INFLAMMASOME; MALONALDEHYDE; MANGANESE SUPEROXIDE DISMUTASE; MITOCHONDRIAL DNA; REACTIVE OXYGEN METABOLITE; TRANSCRIPTION FACTOR NRF2;

EID: 84879606778     PISSN: 0304324X     EISSN: 14230003     Source Type: Journal    
DOI: 10.1159/000346169     Document Type: Review

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