-
1
-
-
0026762988
-
Interleukin 4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activation
-
Stein M., Keshav S., Harris N., Gordon S. Interleukin 4 potently enhances murine macrophage mannose receptor activity: a marker of alternative immunologic macrophage activation. J. Exp. Med. 1992, 176:287-292.
-
(1992)
J. Exp. Med.
, vol.176
, pp. 287-292
-
-
Stein, M.1
Keshav, S.2
Harris, N.3
Gordon, S.4
-
2
-
-
84897556094
-
The M1 and M2 paradigm of macrophage activation: time for reassessment
-
Martinez F.O., Gordon S. The M1 and M2 paradigm of macrophage activation: time for reassessment. F1000prime Rep. 2014, 6:13.
-
(2014)
F1000prime Rep.
, vol.6
, pp. 13
-
-
Martinez, F.O.1
Gordon, S.2
-
3
-
-
20144372362
-
CD40 signaling regulates innate and adaptive activation of microglia in response to amyloid beta-peptide
-
Townsend K.P., Town T., Mori T., Lue L.F., Shytle D., et al. CD40 signaling regulates innate and adaptive activation of microglia in response to amyloid beta-peptide. Eur. J. Immunol. 2005, 35:901-910.
-
(2005)
Eur. J. Immunol.
, vol.35
, pp. 901-910
-
-
Townsend, K.P.1
Town, T.2
Mori, T.3
Lue, L.F.4
Shytle, D.5
-
4
-
-
79954802715
-
Human atherosclerotic plaque alternative macrophages display low cholesterol handling but high phagocytosis because of distinct activities of the PPARgamma and LXRalpha pathways
-
Chinetti-Gbaguidi G., Baron M., Bouhlel M.A., Vanhoutte J., Copin C., et al. Human atherosclerotic plaque alternative macrophages display low cholesterol handling but high phagocytosis because of distinct activities of the PPARgamma and LXRalpha pathways. Circ. Res. 2011, 108:985-995.
-
(2011)
Circ. Res.
, vol.108
, pp. 985-995
-
-
Chinetti-Gbaguidi, G.1
Baron, M.2
Bouhlel, M.A.3
Vanhoutte, J.4
Copin, C.5
-
5
-
-
85029420782
-
Bone marrow-derived macrophages from AbetaPP/PS1 mice are sensitized to the effects of inflammatory stimuli
-
Barrett J.P., Minogue A.M., Jones R.S., Ribeiro C., Kelly R.J., Lynch M.A. Bone marrow-derived macrophages from AbetaPP/PS1 mice are sensitized to the effects of inflammatory stimuli. J. Alzheimer's Dis. 2014.
-
(2014)
J. Alzheimer's Dis.
-
-
Barrett, J.P.1
Minogue, A.M.2
Jones, R.S.3
Ribeiro, C.4
Kelly, R.J.5
Lynch, M.A.6
-
6
-
-
68649111832
-
Alternative activation of macrophages: immune function and cellular biology
-
Varin A., Gordon S. Alternative activation of macrophages: immune function and cellular biology. Immunobiology 2009, 214:630-641.
-
(2009)
Immunobiology
, vol.214
, pp. 630-641
-
-
Varin, A.1
Gordon, S.2
-
7
-
-
58749092367
-
Type I IL-4Rs selectively activate IRS-2 to induce target gene expression in macrophages
-
Heller N.M., Qi X., Junttila I.S., Shirey K.A., Vogel S.N., et al. Type I IL-4Rs selectively activate IRS-2 to induce target gene expression in macrophages. Sci. Signal. 2008, 1:ra17.
-
(2008)
Sci. Signal.
, vol.1
, pp. ra17
-
-
Heller, N.M.1
Qi, X.2
Junttila, I.S.3
Shirey, K.A.4
Vogel, S.N.5
-
8
-
-
0028986107
-
Interferon-gamma inhibits macrophage insulin-like growth factor-I synthesis at the transcriptional level
-
Arkins S., Rebeiz N., Brunke-Reese D.L., Biragyn A., Kelley K.W. Interferon-gamma inhibits macrophage insulin-like growth factor-I synthesis at the transcriptional level. Mol. Endocrinol. 1995, 9:350-360.
-
(1995)
Mol. Endocrinol.
, vol.9
, pp. 350-360
-
-
Arkins, S.1
Rebeiz, N.2
Brunke-Reese, D.L.3
Biragyn, A.4
Kelley, K.W.5
-
9
-
-
65549163176
-
A synthetic NCAM-derived mimetic peptide, FGL, exerts anti-inflammatory properties via IGF-1 and interferon-gamma modulation
-
Downer E.J., Cowley T.R., Cox F., Maher F.O., Berezin V., et al. A synthetic NCAM-derived mimetic peptide, FGL, exerts anti-inflammatory properties via IGF-1 and interferon-gamma modulation. J. Neurochem. 2009, 109:1516-1525.
-
(2009)
J. Neurochem.
, vol.109
, pp. 1516-1525
-
-
Downer, E.J.1
Cowley, T.R.2
Cox, F.3
Maher, F.O.4
Berezin, V.5
-
10
-
-
13644253039
-
Downregulation of IL-4-induced signalling in hippocampus contributes to deficits in LTP in the aged rat
-
Maher F.O., Nolan Y., Lynch M.A. Downregulation of IL-4-induced signalling in hippocampus contributes to deficits in LTP in the aged rat. Neurobiol. Aging 2005, 26:717-728.
-
(2005)
Neurobiol. Aging
, vol.26
, pp. 717-728
-
-
Maher, F.O.1
Nolan, Y.2
Lynch, M.A.3
-
11
-
-
84862189232
-
LPS-induced release of IL-6 from glia modulates production of IL-1beta in a JAK2-dependent manner
-
Minogue A.M., Barrett J.P., Lynch M.A. LPS-induced release of IL-6 from glia modulates production of IL-1beta in a JAK2-dependent manner. J. Neuroinflamm. 2012, 9:126.
-
(2012)
J. Neuroinflamm.
, vol.9
, pp. 126
-
-
Minogue, A.M.1
Barrett, J.P.2
Lynch, M.A.3
-
12
-
-
84866392767
-
Induction of IL-4Ralpha-dependent microRNAs identifies PI3K/Akt signaling as essential for IL-4-driven murine macrophage proliferation in vivo
-
Ruckerl D., Jenkins S.J., Laqtom N.N., Gallagher I.J., Sutherland T.E., et al. Induction of IL-4Ralpha-dependent microRNAs identifies PI3K/Akt signaling as essential for IL-4-driven murine macrophage proliferation in vivo. Blood 2012, 120:2307-2316.
-
(2012)
Blood
, vol.120
, pp. 2307-2316
-
-
Ruckerl, D.1
Jenkins, S.J.2
Laqtom, N.N.3
Gallagher, I.J.4
Sutherland, T.E.5
-
13
-
-
0141955107
-
Induction of macrophage insulin-like growth factor-I expression by the Th2 cytokines IL-4 and IL-13
-
Wynes M.W., Riches D.W. Induction of macrophage insulin-like growth factor-I expression by the Th2 cytokines IL-4 and IL-13. J. Immunol. 2003, 171:3550-3559.
-
(2003)
J. Immunol.
, vol.171
, pp. 3550-3559
-
-
Wynes, M.W.1
Riches, D.W.2
-
14
-
-
58149143039
-
Tuning sensitivity to IL-4 and IL-13: differential expression of IL-4Ralpha, IL-13Ralpha1, and gammac regulates relative cytokine sensitivity
-
Junttila I.S., Mizukami K., Dickensheets H., Meier-Schellersheim M., Yamane H., et al. Tuning sensitivity to IL-4 and IL-13: differential expression of IL-4Ralpha, IL-13Ralpha1, and gammac regulates relative cytokine sensitivity. J. Exp. Med. 2008, 205:2595-2608.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 2595-2608
-
-
Junttila, I.S.1
Mizukami, K.2
Dickensheets, H.3
Meier-Schellersheim, M.4
Yamane, H.5
-
15
-
-
44849113635
-
Genetic analysis of the role of the PI3K-Akt pathway in lipopolysaccharide-induced cytokine and tissue factor gene expression in monocytes/macrophages
-
Luyendyk J.P., Schabbauer G.A., Tencati M., Holscher T., Pawlinski R., Mackman N. Genetic analysis of the role of the PI3K-Akt pathway in lipopolysaccharide-induced cytokine and tissue factor gene expression in monocytes/macrophages. J. Immunol. 2008, 180:4218-4226.
-
(2008)
J. Immunol.
, vol.180
, pp. 4218-4226
-
-
Luyendyk, J.P.1
Schabbauer, G.A.2
Tencati, M.3
Holscher, T.4
Pawlinski, R.5
Mackman, N.6
-
16
-
-
0032545279
-
Protein-tyrosine phosphatase Shp-1 is a negative regulator of IL-4- and IL-13-dependent signal transduction
-
Haque S.J., Harbor P., Tabrizi M., Yi T., Williams B.R. Protein-tyrosine phosphatase Shp-1 is a negative regulator of IL-4- and IL-13-dependent signal transduction. J. Biol. Chem. 1998, 273:33893-33896.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 33893-33896
-
-
Haque, S.J.1
Harbor, P.2
Tabrizi, M.3
Yi, T.4
Williams, B.R.5
-
17
-
-
84882658553
-
HDL induces the expression of the M2 macrophage markers arginase 1 and Fizz-1 in a STAT6-dependent process
-
Sanson M., Distel E., Fisher E.A. HDL induces the expression of the M2 macrophage markers arginase 1 and Fizz-1 in a STAT6-dependent process. PloS One 2013, 8:e74676.
-
(2013)
PloS One
, vol.8
, pp. e74676
-
-
Sanson, M.1
Distel, E.2
Fisher, E.A.3
-
18
-
-
0030587813
-
Impaired IL-13-mediated functions of macrophages in STAT6-deficient mice
-
Takeda K., Kamanaka M., Tanaka T., Kishimoto T., Akira S. Impaired IL-13-mediated functions of macrophages in STAT6-deficient mice. J. Immunol. 1996, 157:3220-3222.
-
(1996)
J. Immunol.
, vol.157
, pp. 3220-3222
-
-
Takeda, K.1
Kamanaka, M.2
Tanaka, T.3
Kishimoto, T.4
Akira, S.5
-
19
-
-
0037044580
-
TH2 cytokines and allergic challenge induce Ym1 expression in macrophages by a STAT6-dependent mechanism
-
Welch J.S., Escoubet-Lozach L., Sykes D.B., Liddiard K., Greaves D.R., Glass C.K. TH2 cytokines and allergic challenge induce Ym1 expression in macrophages by a STAT6-dependent mechanism. J. Biol. Chem. 2002, 277:42821-42829.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 42821-42829
-
-
Welch, J.S.1
Escoubet-Lozach, L.2
Sykes, D.B.3
Liddiard, K.4
Greaves, D.R.5
Glass, C.K.6
-
20
-
-
77953268611
-
Alternative activation of macrophages: mechanism and functions
-
Gordon S., Martinez F.O. Alternative activation of macrophages: mechanism and functions. Immunity 2010, 32:593-604.
-
(2010)
Immunity
, vol.32
, pp. 593-604
-
-
Gordon, S.1
Martinez, F.O.2
-
21
-
-
84874776157
-
Insulin-like growth factor 1 and 2 (IGF1, IGF2) expression in human microglia: differential regulation by inflammatory mediators
-
Suh H.S., Zhao M.L., Derico L., Choi N., Lee S.C. Insulin-like growth factor 1 and 2 (IGF1, IGF2) expression in human microglia: differential regulation by inflammatory mediators. J. Neuroinflammation 2013, 10:37.
-
(2013)
J. Neuroinflammation
, vol.10
, pp. 37
-
-
Suh, H.S.1
Zhao, M.L.2
Derico, L.3
Choi, N.4
Lee, S.C.5
-
22
-
-
84879513391
-
Astrocyte-specific overexpression of insulin-like growth factor-1 protects hippocampal neurons and reduces behavioral deficits following traumatic brain injury in mice
-
Madathil S.K., Carlson S.W., Brelsfoard J.M., Ye P., D'Ercole A.J., Saatman K.E. Astrocyte-specific overexpression of insulin-like growth factor-1 protects hippocampal neurons and reduces behavioral deficits following traumatic brain injury in mice. PloS One 2013, 8:e67204.
-
(2013)
PloS One
, vol.8
, pp. e67204
-
-
Madathil, S.K.1
Carlson, S.W.2
Brelsfoard, J.M.3
Ye, P.4
D'Ercole, A.J.5
Saatman, K.E.6
-
23
-
-
78649339985
-
An age-related sprouting transcriptome provides molecular control of axonal sprouting after stroke
-
Li S.L., Overman J.J., Katsman D., Kozlov S.V., Donnelly C.J., et al. An age-related sprouting transcriptome provides molecular control of axonal sprouting after stroke. Nat. Neurosci. 2010, 13:1496-1504.
-
(2010)
Nat. Neurosci.
, vol.13
, pp. 1496-1504
-
-
Li, S.L.1
Overman, J.J.2
Katsman, D.3
Kozlov, S.V.4
Donnelly, C.J.5
-
25
-
-
0036628509
-
IGF-I and microglia/macrophage proliferation in the ischemic mouse brain
-
O'Donnell S.L., Frederick T.J., Krady J.K., Vannucci S.J., Wood T.L. IGF-I and microglia/macrophage proliferation in the ischemic mouse brain. Glia 2002, 39:85-97.
-
(2002)
Glia
, vol.39
, pp. 85-97
-
-
O'Donnell, S.L.1
Frederick, T.J.2
Krady, J.K.3
Vannucci, S.J.4
Wood, T.L.5
-
26
-
-
79957579025
-
Alternative activation of macrophages by IL-4 requires SHIP degradation
-
Weisser S.B., McLarren K.W., Voglmaier N., van Netten-Thomas C.J., Antov A., et al. Alternative activation of macrophages by IL-4 requires SHIP degradation. Eur. J. Immunol. 2011, 41:1742-1753.
-
(2011)
Eur. J. Immunol.
, vol.41
, pp. 1742-1753
-
-
Weisser, S.B.1
McLarren, K.W.2
Voglmaier, N.3
van Netten-Thomas, C.J.4
Antov, A.5
-
27
-
-
78650642949
-
Phosphatidylinositol 3-kinase activation attenuates the TLR2-mediated macrophage proinflammatory cytokine response to Francisella tularensis live vaccine strain
-
Medina E.A., Morris I.R., Berton M.T. Phosphatidylinositol 3-kinase activation attenuates the TLR2-mediated macrophage proinflammatory cytokine response to Francisella tularensis live vaccine strain. J. Immunol. 2010, 185:7562-7572.
-
(2010)
J. Immunol.
, vol.185
, pp. 7562-7572
-
-
Medina, E.A.1
Morris, I.R.2
Berton, M.T.3
-
28
-
-
5344249335
-
PI3K-Akt pathway suppresses coagulation and inflammation in endotoxemic mice
-
Schabbauer G., Tencati M., Pedersen B., Pawlinski R., Mackman N. PI3K-Akt pathway suppresses coagulation and inflammation in endotoxemic mice. Arterioscler. Thromb. Vasc. Biol. 2004, 24:1963-1969.
-
(2004)
Arterioscler. Thromb. Vasc. Biol.
, vol.24
, pp. 1963-1969
-
-
Schabbauer, G.1
Tencati, M.2
Pedersen, B.3
Pawlinski, R.4
Mackman, N.5
-
29
-
-
0346103719
-
Modulation of the phosphoinositide 3-kinase pathway alters innate resistance to polymicrobial sepsis
-
Williams D.L., Li C., Ha T., Ozment-Skelton T., Kalbfleisch J.H., et al. Modulation of the phosphoinositide 3-kinase pathway alters innate resistance to polymicrobial sepsis. J. Immunol. 2004, 172:449-456.
-
(2004)
J. Immunol.
, vol.172
, pp. 449-456
-
-
Williams, D.L.1
Li, C.2
Ha, T.3
Ozment-Skelton, T.4
Kalbfleisch, J.H.5
-
30
-
-
84903371932
-
Age-associated dysregulation of microglial activation is coupled with enhanced blood-brain barrier permeability and pathology in APP/PS1 mice
-
Minogue A.M., Jones R.S., Kelly R.J., McDonald C.L., Connor T.J., Lynch M.A. Age-associated dysregulation of microglial activation is coupled with enhanced blood-brain barrier permeability and pathology in APP/PS1 mice. Neurobiol. Aging 2014, 35:1442-1452.
-
(2014)
Neurobiol. Aging
, vol.35
, pp. 1442-1452
-
-
Minogue, A.M.1
Jones, R.S.2
Kelly, R.J.3
McDonald, C.L.4
Connor, T.J.5
Lynch, M.A.6
|