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Volumn 2014, Issue 1, 2014, Pages 71-76

Biology of BM failure syndromes: Role of microenvironment and niches

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MODEL; HEMATOPOIESIS; HUMAN; MOLECULARLY TARGETED THERAPY; PAROXYSMAL NOCTURNAL HEMOGLOBINURIA; PATHOLOGY; STEM CELL NICHE; TUMOR MICROENVIRONMENT;

EID: 84937571755     PISSN: 15204391     EISSN: 15204383     Source Type: Journal    
DOI: 10.1182/asheducation-2014.1.71     Document Type: Article
Times cited : (27)

References (79)
  • 1
    • 79959851207 scopus 로고    scopus 로고
    • Incidence of the myelodysplastic syndromes using a novel claims-based algorithm: High number of uncaptured cases by cancer registries
    • Cogle CR, Craig BM, Rollison DE, List AF. Incidence of the myelodysplastic syndromes using a novel claims-based algorithm: high number of uncaptured cases by cancer registries. Blood. 2011;117(26): 7121-7125.
    • (2011) Blood , vol.117 , Issue.26 , pp. 7121-7125
    • Cogle, C.R.1    Craig, B.M.2    Rollison, D.E.3    List, A.F.4
  • 2
    • 79961232055 scopus 로고    scopus 로고
    • Health care utilization and mortality among elderly patients with myelodysplastic syndromes
    • Lindquist KJ, Danese MD, Mikhael J, Knopf KB, Griffiths RI. Health care utilization and mortality among elderly patients with myelodysplastic syndromes. Ann Oncol. 2011;22(5):1181-1188.
    • (2011) Ann Oncol , vol.22 , Issue.5 , pp. 1181-1188
    • Lindquist, K.J.1    Danese, M.D.2    Mikhael, J.3    Knopf, K.B.4    Griffiths, R.I.5
  • 3
    • 84897132895 scopus 로고    scopus 로고
    • Nice neighborhood: Emerging concepts of the stem cell niche
    • Scadden DT. Nice neighborhood: emerging concepts of the stem cell niche. Cell. 2014;157(1):41-50.
    • (2014) Cell , vol.157 , Issue.1 , pp. 41-50
    • Scadden, D.T.1
  • 4
    • 0030684749 scopus 로고    scopus 로고
    • Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts [see comments]
    • Komori T, Yagi H, Nomura S, et al. Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts [see comments]. Cell. 1997;89(5):755-764.
    • (1997) Cell , vol.89 , Issue.5 , pp. 755-764
    • Komori, T.1    Yagi, H.2    Nomura, S.3
  • 5
    • 0030051856 scopus 로고    scopus 로고
    • Human osteoblasts support human hematopoietic progenitor cells in vitro bone BM cultures
    • Taichman RS, Reilly MJ, Emerson SG. Human osteoblasts support human hematopoietic progenitor cells in vitro bone BM cultures. Blood. 1996;87(2):518-524.
    • (1996) Blood , vol.87 , Issue.2 , pp. 518-524
    • Taichman, R.S.1    Reilly, M.J.2    Emerson, S.G.3
  • 6
    • 0242268524 scopus 로고    scopus 로고
    • Osteoblastic cells regulate the haematopoietic stem cell niche
    • Calvi LM, Adams GB, Weibrecht KW, et al. Osteoblastic cells regulate the haematopoietic stem cell niche. Nature. 2003;425(6960):841-846.
    • (2003) Nature , vol.425 , Issue.6960 , pp. 841-846
    • Calvi, L.M.1    Adams, G.B.2    Weibrecht, K.W.3
  • 7
    • 0242363225 scopus 로고    scopus 로고
    • Identification of the haematopoietic stem cell niche and control of the niche size
    • Zhang J, Niu C, Ye L, et al. Identification of the haematopoietic stem cell niche and control of the niche size. Nature. 2003;425(6960):836-841.
    • (2003) Nature , vol.425 , Issue.6960 , pp. 836-841
    • Zhang, J.1    Niu, C.2    Ye, L.3
  • 8
    • 77955646193 scopus 로고    scopus 로고
    • Mesenchymal and haematopoietic stem cells form a unique bone marrow niche
    • Mendez-Ferrer S, Michurina TV, Ferraro F, et al. Mesenchymal and haematopoietic stem cells form a unique bone marrow niche. Nature. 2010;466(7308):829-834.
    • (2010) Nature , vol.466 , Issue.7308 , pp. 829-834
    • Mendez-Ferrer, S.1    Michurina, T.V.2    Ferraro, F.3
  • 9
    • 84874997081 scopus 로고    scopus 로고
    • CXCL12 in early mesenchymal progenitors is required for haematopoietic stem-cell maintenance
    • Greenbaum A, Hsu YM, Day RB, et al. CXCL12 in early mesenchymal progenitors is required for haematopoietic stem-cell maintenance. Nature. 2013;495(7440):227-230.
    • (2013) Nature , vol.495 , Issue.7440 , pp. 227-230
    • Greenbaum, A.1    Hsu, Y.M.2    Day, R.B.3
  • 10
    • 84875000886 scopus 로고    scopus 로고
    • Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches
    • Ding L, Morrison SJ. Haematopoietic stem cells and early lymphoid progenitors occupy distinct bone marrow niches. Nature. 2013; 495(7440):231-235.
    • (2013) Nature , vol.495 , Issue.7440 , pp. 231-235
    • Ding, L.1    Morrison, S.J.2
  • 11
    • 21244463426 scopus 로고    scopus 로고
    • SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells
    • Kiel MJ, Yilmaz OH, Iwashita T, Terhorst C, Morrison SJ. SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells. Cell. 2005;121(7):1109-1121.
    • (2005) Cell , vol.121 , Issue.7 , pp. 1109-1121
    • Kiel, M.J.1    Yilmaz, O.H.2    Iwashita, T.3    Terhorst, C.4    Morrison, S.J.5
  • 12
    • 60849138787 scopus 로고    scopus 로고
    • Engraftment and reconstitution of hematopoiesis is dependent on VEGFR2-mediated regeneration of sinusoidal endothelial cells
    • Hooper AT, Butler JM, Nolan DJ, et al. Engraftment and reconstitution of hematopoiesis is dependent on VEGFR2-mediated regeneration of sinusoidal endothelial cells. Cell Stem Cell. 2009;4(3):263-274.
    • (2009) Cell Stem Cell , vol.4 , Issue.3 , pp. 263-274
    • Hooper, A.T.1    Butler, J.M.2    Nolan, D.J.3
  • 13
    • 84886947010 scopus 로고    scopus 로고
    • Arteriolar niches maintain haematopoietic stem cell quiescence
    • Kunisaki Y, Bruns I, Scheiermann C, et al. Arteriolar niches maintain haematopoietic stem cell quiescence. Nature. 2013;502(7473):637-643.
    • (2013) Nature , vol.502 , Issue.7473 , pp. 637-643
    • Kunisaki, Y.1    Bruns, I.2    Scheiermann, C.3
  • 14
    • 0025741349 scopus 로고
    • Identification of stromal cell precursors in human bone marrow by a novel monoclonal antibody, STRO-1
    • Simmons PJ, Torok-Storb B. Identification of stromal cell precursors in human bone marrow by a novel monoclonal antibody, STRO-1. Blood. 1991;78(1):55-62.
    • (1991) Blood , vol.78 , Issue.1 , pp. 55-62
    • Simmons, P.J.1    Torok-Storb, B.2
  • 15
    • 0025720031 scopus 로고
    • CD34 expression by stromal precursors in normal human adult bone marrow
    • Simmons PJ, Torok-Storb B. CD34 expression by stromal precursors in normal human adult bone marrow. Blood. 1991;78(11):2848-2853.
    • (1991) Blood , vol.78 , Issue.11 , pp. 2848-2853
    • Simmons, P.J.1    Torok-Storb, B.2
  • 16
    • 84867747480 scopus 로고    scopus 로고
    • Monocytes-macrophages that express alpha-smooth muscle actin preserve primitive hematopoietic cells in the bone marrow
    • Ludin A, Itkin T, Gur-Cohen S, et al. Monocytes-macrophages that express alpha-smooth muscle actin preserve primitive hematopoietic cells in the bone marrow. Nat Immunol. 2012;13(11):1072-1082.
    • (2012) Nat Immunol , vol.13 , Issue.11 , pp. 1072-1082
    • Ludin, A.1    Itkin, T.2    Gur-Cohen, S.3
  • 17
    • 79951694373 scopus 로고    scopus 로고
    • Bone marrow CD169+ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche
    • Chow A, Lucas D, Hidalgo A, et al. Bone marrow CD169+ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche. J Exp Med. 2011;208(2):261-271.
    • (2011) J Exp Med , vol.208 , Issue.2 , pp. 261-271
    • Chow, A.1    Lucas, D.2    Hidalgo, A.3
  • 18
  • 19
    • 81855183667 scopus 로고    scopus 로고
    • Nonmyelinating Schwann cells maintain hematopoietic stem cell hibernation in the bone marrow niche
    • Yamazaki S, Ema H, Karlsson G, et al. Nonmyelinating Schwann cells maintain hematopoietic stem cell hibernation in the bone marrow niche. Cell. 2011;147(5):1146-1158.
    • (2011) Cell , vol.147 , Issue.5 , pp. 1146-1158
    • Yamazaki, S.1    Ema, H.2    Karlsson, G.3
  • 20
    • 84869788379 scopus 로고    scopus 로고
    • PTH expands short-term murine hemopoietic stem cells through T cells
    • Li JY, Adams J, Calvi LM, et al. PTH expands short-term murine hemopoietic stem cells through T cells. Blood. 2012;120(22):4352-4362.
    • (2012) Blood , vol.120 , Issue.22 , pp. 4352-4362
    • Li, J.Y.1    Adams, J.2    Calvi, L.M.3
  • 21
    • 67650504733 scopus 로고    scopus 로고
    • Bone-marrow adipocytes as negative regulators of the haematopoietic microenvironment
    • Naveiras O, Nardi V, Wenzel PL, Hauschka PV, Fahey F, Daley GQ. Bone-marrow adipocytes as negative regulators of the haematopoietic microenvironment. Nature. 2009;460(7252):259-263.
    • (2009) Nature , vol.460 , Issue.7252 , pp. 259-263
    • Naveiras, O.1    Nardi, V.2    Wenzel, P.L.3    Hauschka, P.V.4    Fahey, F.5    Daley, G.Q.6
  • 22
    • 39749164920 scopus 로고    scopus 로고
    • Haematopoietic stem cell release is regulated by circadian oscillations
    • Mendez-Ferrer S, Lucas D, Battista M, Frenette PS. Haematopoietic stem cell release is regulated by circadian oscillations. Nature. 2008; 452(7186):442-447.
    • (2008) Nature , vol.452 , Issue.7186 , pp. 442-447
    • Mendez-Ferrer, S.1    Lucas, D.2    Battista, M.3    Frenette, P.S.4
  • 23
    • 84864063975 scopus 로고    scopus 로고
    • Osteoblastic N-cadherin is not required for microenvironmental support and regulation of hematopoietic stem and progenitor cells
    • Bromberg O, Frisch BJ, Weber JM, Porter RL, Civitelli R, Calvi LM. Osteoblastic N-cadherin is not required for microenvironmental support and regulation of hematopoietic stem and progenitor cells. Blood. 2012;120(2):303-313.
    • (2012) Blood , vol.120 , Issue.2 , pp. 303-313
    • Bromberg, O.1    Frisch, B.J.2    Weber, J.M.3    Porter, R.L.4    Civitelli, R.5    Calvi, L.M.6
  • 24
    • 84885608862 scopus 로고    scopus 로고
    • Physiologic corticosterone oscillations regulate murine hematopoietic stem/progenitor cell proliferation and CXCL12 expression by bone marrow stromal progenitors
    • Kollet O, Vagima Y, D'Uva G, et al. Physiologic corticosterone oscillations regulate murine hematopoietic stem/progenitor cell proliferation and CXCL12 expression by bone marrow stromal progenitors. Leukemia. 2013;27(10):2006-2015.
    • (2013) Leukemia , vol.27 , Issue.10 , pp. 2006-2015
    • Kollet, O.1    Vagima, Y.2    D'Uva, G.3
  • 25
    • 84892702777 scopus 로고    scopus 로고
    • Oestrogen increases haematopoietic stem-cell self-renewal in females and during pregnancy
    • Nakada D, Oguro H, Levi BP, et al. Oestrogen increases haematopoietic stem-cell self-renewal in females and during pregnancy. Nature. 2014;505(7484):555-558.
    • (2014) Nature , vol.505 , Issue.7484 , pp. 555-558
    • Nakada, D.1    Oguro, H.2    Levi, B.P.3
  • 26
    • 84900342698 scopus 로고    scopus 로고
    • Direct measurement of local oxygen concentration in the bone marrow of live animals
    • Spencer JA, Ferraro F, Roussakis E, et al. Direct measurement of local oxygen concentration in the bone marrow of live animals. Nature. 2014;508(7495):269-273.
    • (2014) Nature , vol.508 , Issue.7495 , pp. 269-273
    • Spencer, J.A.1    Ferraro, F.2    Roussakis, E.3
  • 27
    • 84871071832 scopus 로고    scopus 로고
    • Cord-blood engraftment with ex vivo mesenchymal-cell coculture
    • de Lima M, McNiece I, Robinson SN, et al. Cord-blood engraftment with ex vivo mesenchymal-cell coculture. N Engl J Med. 2012;367(24): 2305-2315.
    • (2012) N Engl J Med , vol.367 , Issue.24 , pp. 2305-2315
    • De Lima, M.1    McNiece, I.2    Robinson, S.N.3
  • 28
    • 55949114758 scopus 로고    scopus 로고
    • Osteoblastic regulation of B lymphopoiesis is mediated by Gs{alpha}-dependent signaling pathways
    • Wu JY, Purton LE, Rodda SJ, et al. Osteoblastic regulation of B lymphopoiesis is mediated by Gs{alpha}-dependent signaling pathways. Proc Natl Acad Sci U S A. 2008;105(44):16976-16981.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , Issue.44 , pp. 16976-16981
    • Wu, J.Y.1    Purton, L.E.2    Rodda, S.J.3
  • 29
    • 84873575928 scopus 로고    scopus 로고
    • Myelopoiesis is regulated by osteocytes through Gsalpha-dependent signaling
    • Fulzele K, Krause DS, Panaroni C, et al. Myelopoiesis is regulated by osteocytes through Gsalpha-dependent signaling. Blood. 2013;121(6): 930-939.
    • (2013) Blood , vol.121 , Issue.6 , pp. 930-939
    • Fulzele, K.1    Krause, D.S.2    Panaroni, C.3
  • 30
    • 58149388329 scopus 로고    scopus 로고
    • Defective Notch activation in microenvironment leads to myeloproliferative disease
    • Kim YW, Koo BK, Jeong HW, et al. Defective Notch activation in microenvironment leads to myeloproliferative disease. Blood. 2008; 112(12):4628-4638.
    • (2008) Blood , vol.112 , Issue.12 , pp. 4628-4638
    • Kim, Y.W.1    Koo, B.K.2    Jeong, H.W.3
  • 31
    • 34250331610 scopus 로고    scopus 로고
    • A microenvironment-induced myeloproliferative syndrome caused by retinoic acid receptor gamma deficiency
    • Walkley CR, Olsen GH, Dworkin S, et al. A microenvironment-induced myeloproliferative syndrome caused by retinoic acid receptor gamma deficiency. Cell. 2007;129(6):1097-1110.
    • (2007) Cell , vol.129 , Issue.6 , pp. 1097-1110
    • Walkley, C.R.1    Olsen, G.H.2    Dworkin, S.3
  • 32
    • 84893917461 scopus 로고    scopus 로고
    • Leukaemogenesis induced by an activating beta-catenin mutation in osteoblasts
    • Kode A, Manavalan JS, Mosialou I, et al. Leukaemogenesis induced by an activating beta-catenin mutation in osteoblasts. Nature. 2014; 506(7487):240-244.
    • (2014) Nature , vol.506 , Issue.7487 , pp. 240-244
    • Kode, A.1    Manavalan, J.S.2    Mosialou, I.3
  • 33
    • 33750628439 scopus 로고    scopus 로고
    • Current concepts in the pathophysiology and treatment of aplastic anemia
    • Young NS, Calado RT, Scheinberg P. Current concepts in the pathophysiology and treatment of aplastic anemia. Blood. 2006;108(8):2509-2519.
    • (2006) Blood , vol.108 , Issue.8 , pp. 2509-2519
    • Young, N.S.1    Calado, R.T.2    Scheinberg, P.3
  • 34
    • 0014953726 scopus 로고
    • Bone marrow graft in man after conditioning by antilymphocytic serum
    • Mathe G, Amiel JL, Schwarzenberg L, et al. Bone marrow graft in man after conditioning by antilymphocytic serum. Br Med J. 1970;2(5702): 131-136.
    • (1970) Br Med J , vol.2 , Issue.5702 , pp. 131-136
    • Mathe, G.1    Amiel, J.L.2    Schwarzenberg, L.3
  • 35
    • 0031034490 scopus 로고    scopus 로고
    • Results of transplanting bone marrow from genetically identical twins into patients with aplastic anemia
    • Hinterberger W, Rowlings PA, Hinterberger-Fischer M, et al. Results of transplanting bone marrow from genetically identical twins into patients with aplastic anemia. Ann Intern Med. 1997;126(2):116-122.
    • (1997) Ann Intern Med , vol.126 , Issue.2 , pp. 116-122
    • Hinterberger, W.1    Rowlings, P.A.2    Hinterberger-Fischer, M.3
  • 36
    • 84896319709 scopus 로고    scopus 로고
    • Idiopathic aplastic anemia: Diagnosis and classification
    • Dolberg OJ, Levy Y. Idiopathic aplastic anemia: Diagnosis and classification. Autoimmun Rev. 2014;13(4-5):569-573.
    • (2014) Autoimmun Rev , vol.13 , Issue.4-5 , pp. 569-573
    • Dolberg, O.J.1    Levy, Y.2
  • 37
    • 0017362159 scopus 로고
    • Suppression of erythroid-colony formation by lymphocytes from patients with aplastic anemia
    • Hoffman R, Zanjani ED, Lutton JD, Zalusky R, Wasserman LR. Suppression of erythroid-colony formation by lymphocytes from patients with aplastic anemia. N Engl J Med. 1977;296(1):10-13.
    • (1977) N Engl J Med , vol.296 , Issue.1 , pp. 10-13
    • Hoffman, R.1    Zanjani, E.D.2    Lutton, J.D.3    Zalusky, R.4    Wasserman, L.R.5
  • 38
    • 3242782610 scopus 로고    scopus 로고
    • In-vivo dominant immune responses in aplastic anaemia: Molecular tracking of putatively pathogenetic T-cell clones by TCR beta-CDR3 sequencing
    • Risitano AM, Maciejewski JP, Green S, Plasilova M, Zeng W, Young NS. In-vivo dominant immune responses in aplastic anaemia: molecular tracking of putatively pathogenetic T-cell clones by TCR beta-CDR3 sequencing. Lancet. 2004;364(9431):355-364.
    • (2004) Lancet , vol.364 , Issue.9431 , pp. 355-364
    • Risitano, A.M.1    Maciejewski, J.P.2    Green, S.3    Plasilova, M.4    Zeng, W.5    Young, N.S.6
  • 39
    • 84868340676 scopus 로고    scopus 로고
    • Differential gene expression profile associated with the abnormality of bone marrow mesenchymal stem cells in aplastic anemia
    • Li J, Yang S, Lu S, et al. Differential gene expression profile associated with the abnormality of bone marrow mesenchymal stem cells in aplastic anemia. PLoS One. 2012;7(11):e47764.
    • (2012) PLoS One , vol.7 , Issue.11 , pp. e47764
    • Li, J.1    Yang, S.2    Lu, S.3
  • 40
    • 84869788379 scopus 로고    scopus 로고
    • PTH expands short-term murine hemopoietic stem cells through T cells
    • Li JY, Adams J, Calvi LM, et al. PTH expands short-term murine hemopoietic stem cells through T cells. Blood. 2012;120(22):4352-4362.
    • (2012) Blood , vol.120 , Issue.22 , pp. 4352-4362
    • Li, J.Y.1    Adams, J.2    Calvi, L.M.3
  • 41
    • 84887734708 scopus 로고    scopus 로고
    • Ovariectomy expands murine short-term hemopoietic stem cell function through T cell expressed CD40L and Wnt10B
    • Li JY, Adams J, Calvi LM, Lane TF, Weitzmann MN, Pacifici R. Ovariectomy expands murine short-term hemopoietic stem cell function through T cell expressed CD40L and Wnt10B. Blood. 2013;122(14): 2346-2357.
    • (2013) Blood , vol.122 , Issue.14 , pp. 2346-2357
    • Li, J.Y.1    Adams, J.2    Calvi, L.M.3    Lane, T.F.4    Weitzmann, M.N.5    Pacifici, R.6
  • 42
    • 79958279325 scopus 로고    scopus 로고
    • In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche
    • Fujisaki J, Wu J, Carlson AL, et al. In vivo imaging of Treg cells providing immune privilege to the haematopoietic stem-cell niche. Nature. 2011;474(7350):216-219.
    • (2011) Nature , vol.474 , Issue.7350 , pp. 216-219
    • Fujisaki, J.1    Wu, J.2    Carlson, A.L.3
  • 43
    • 77950862042 scopus 로고    scopus 로고
    • Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia
    • Raaijmakers MH, Mukherjee S, Guo S, et al. Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia. Nature. 2010; 464(7290):852-857.
    • (2010) Nature , vol.464 , Issue.7290 , pp. 852-857
    • Raaijmakers, M.H.1    Mukherjee, S.2    Guo, S.3
  • 44
    • 0033230361 scopus 로고    scopus 로고
    • Shwachman-Diamond syndrome: An inherited preleukemic bone marrow failure disorder with aberrant hematopoietic progenitors and faulty marrow microenvironment
    • Dror Y, Freedman M. Shwachman-Diamond syndrome: an inherited preleukemic bone marrow failure disorder with aberrant hematopoietic progenitors and faulty marrow microenvironment. Blood. 1999;94:3048-3054.
    • (1999) Blood , vol.94 , pp. 3048-3054
    • Dror, Y.1    Freedman, M.2
  • 45
    • 84871067796 scopus 로고    scopus 로고
    • Mesenchymal stem cells from Shwachman-Diamond syndrome patients display normal functions and do not contribute to hematological defects
    • Andre V, Longoni D, Bresolin S, et al. Mesenchymal stem cells from Shwachman-Diamond syndrome patients display normal functions and do not contribute to hematological defects. Blood Cancer J. 2012;2:e94.
    • (2012) Blood Cancer J , vol.2 , pp. e94
    • Andre, V.1    Longoni, D.2    Bresolin, S.3
  • 46
    • 64049091680 scopus 로고    scopus 로고
    • Mesenchymal stem/progenitor cells promote the reconstitution of exogenous hematopoietic stem cells in Fancg-/-mice in vivo
    • Li Y, Chen S, Yuan J, et al. Mesenchymal stem/progenitor cells promote the reconstitution of exogenous hematopoietic stem cells in Fancg-/-mice in vivo. Blood. 2009;113(10):2342-2351.
    • (2009) Blood , vol.113 , Issue.10 , pp. 2342-2351
    • Li, Y.1    Chen, S.2    Yuan, J.3
  • 47
    • 0031979845 scopus 로고    scopus 로고
    • Localization of Fas and Fas ligand in bone marrow cells demonstrating myelodysplasia
    • Kitagawa M, Yamaguchi S, Takahashi M, Tanizawa T, Hirokawa K, Kamiyama R. Localization of Fas and Fas ligand in bone marrow cells demonstrating myelodysplasia. Leukemia. 1998;12(4):486-492.
    • (1998) Leukemia , vol.12 , Issue.4 , pp. 486-492
    • Kitagawa, M.1    Yamaguchi, S.2    Takahashi, M.3    Tanizawa, T.4    Hirokawa, K.5    Kamiyama, R.6
  • 48
    • 0034490531 scopus 로고    scopus 로고
    • Abnormalities of adherent layers grown from bone marrow of patients with myelodysplasia
    • Tennant GB, Walsh V, Truran LN, Edwards P, Mills KI, Burnett AK. Abnormalities of adherent layers grown from bone marrow of patients with myelodysplasia. Br J Haematol. 2000;111(3):853-862.
    • (2000) Br J Haematol , vol.111 , Issue.3 , pp. 853-862
    • Tennant, G.B.1    Walsh, V.2    Truran, L.N.3    Edwards, P.4    Mills, K.I.5    Burnett, A.K.6
  • 49
    • 84886998745 scopus 로고    scopus 로고
    • Mesenchymal stromal cells from patients with myelodyplastic syndrome display distinct functional alterations that are modulated by lenalidomide
    • Ferrer RA, Wobus M, List C, et al. Mesenchymal stromal cells from patients with myelodyplastic syndrome display distinct functional alterations that are modulated by lenalidomide. Haematologica. 2013; 98(11):1677-1685.
    • (2013) Haematologica , vol.98 , Issue.11 , pp. 1677-1685
    • Ferrer, R.A.1    Wobus, M.2    List, C.3
  • 50
    • 84883740609 scopus 로고    scopus 로고
    • Insufficient stromal support in MDS results from molecular and functional deficits of mesenchymal stromal cells
    • Geyh S, Oz S, Cadeddu RP, et al. Insufficient stromal support in MDS results from molecular and functional deficits of mesenchymal stromal cells. Leukemia. 2013;27(9):1841-1851.
    • (2013) Leukemia , vol.27 , Issue.9 , pp. 1841-1851
    • Geyh, S.1    Oz, S.2    Cadeddu, R.P.3
  • 51
    • 23044473715 scopus 로고    scopus 로고
    • Preferential suppression of trisomy 8 compared with normal hematopoietic cell growth by autologous lymphocytes in patients with trisomy 8 myelodysplastic syndrome
    • Sloand EM, Mainwaring L, Fuhrer M, et al. Preferential suppression of trisomy 8 compared with normal hematopoietic cell growth by autologous lymphocytes in patients with trisomy 8 myelodysplastic syndrome. Blood. 2005;106(3):841-851.
    • (2005) Blood , vol.106 , Issue.3 , pp. 841-851
    • Sloand, E.M.1    Mainwaring, L.2    Fuhrer, M.3
  • 52
    • 45149093744 scopus 로고    scopus 로고
    • Factors affecting response and survival in patients with myelodysplasia treated with immunosuppressive therapy
    • Sloand EM, Wu CO, Greenberg P, Young N, Barrett J. Factors affecting response and survival in patients with myelodysplasia treated with immunosuppressive therapy. J Clin Oncol. 2008;26(15):2505-2511.
    • (2008) J Clin Oncol , vol.26 , Issue.15 , pp. 2505-2511
    • Sloand, E.M.1    Wu, C.O.2    Greenberg, P.3    Young, N.4    Barrett, J.5
  • 53
    • 34249740754 scopus 로고    scopus 로고
    • Reduced natural killer(NK) function associated with high-risk myelodysplastic syndrome (MDS) and reduced expression of activating NK receptors
    • Epling-Burnette PK, Bai F, Painter JS, et al. Reduced natural killer(NK) function associated with high-risk myelodysplastic syndrome (MDS) and reduced expression of activating NK receptors. Blood. 2007;109(11): 4816-4824.
    • (2007) Blood , vol.109 , Issue.11 , pp. 4816-4824
    • Epling-Burnette, P.K.1    Bai, F.2    Painter, J.S.3
  • 54
    • 42949095542 scopus 로고    scopus 로고
    • Dysregulation of IL-32 in myelodysplastic syndrome and chronic myelomonocytic leukemia modulates apoptosis and impairs NK function
    • Marcondes AM, Mhyre AJ, Stirewalt DL, Kim SH, Dinarello CA, Deeg HJ. Dysregulation of IL-32 in myelodysplastic syndrome and chronic myelomonocytic leukemia modulates apoptosis and impairs NK function. Proc Natl Acad Sci U S A. 2008;105(8):2865-2870.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , Issue.8 , pp. 2865-2870
    • Marcondes, A.M.1    Mhyre, A.J.2    Stirewalt, D.L.3    Kim, S.H.4    Dinarello, C.A.5    Deeg, H.J.6
  • 55
    • 62249219784 scopus 로고    scopus 로고
    • Advancements in the molecular pathogenesis of myelodysplastic syndrome
    • Epling-Burnette PK, List AF. Advancements in the molecular pathogenesis of myelodysplastic syndrome. Curr Opin Hematol. 2009;16(2):70-76.
    • (2009) Curr Opin Hematol , vol.16 , Issue.2 , pp. 70-76
    • Epling-Burnette, P.K.1    List, A.F.2
  • 56
    • 13244290233 scopus 로고    scopus 로고
    • Evidence for a role of TNF-related apoptosis-inducing ligand (TRAIL) in the anemia of myelodysplastic syndromes
    • Campioni D, Secchiero P, Corallini F, et al. Evidence for a role of TNF-related apoptosis-inducing ligand (TRAIL) in the anemia of myelodysplastic syndromes. Am J Pathol. 2005;166(2):557-563.
    • (2005) Am J Pathol , vol.166 , Issue.2 , pp. 557-563
    • Campioni, D.1    Secchiero, P.2    Corallini, F.3
  • 57
    • 0037411227 scopus 로고    scopus 로고
    • Expression of TNF receptors and related signaling molecules in the bone marrow from patients with myelodysplastic syndromes
    • Sawanobori M, Yamaguchi S, Hasegawa M, et al. Expression of TNF receptors and related signaling molecules in the bone marrow from patients with myelodysplastic syndromes. Leuk Res. 2003;27(7):583-591.
    • (2003) Leuk Res , vol.27 , Issue.7 , pp. 583-591
    • Sawanobori, M.1    Yamaguchi, S.2    Hasegawa, M.3
  • 58
    • 0036236034 scopus 로고    scopus 로고
    • In vitro characterization of hematopoietic microenvironment cells from patients with myelodysplastic syndrome
    • Flores-Figueroa E, Gutierrez-Espindola G, Montesinos JJ, Arana-Trejo RM, Mayani H. In vitro characterization of hematopoietic microenvironment cells from patients with myelodysplastic syndrome. Leuk Res. 2002;26(7):677-686.
    • (2002) Leuk Res , vol.26 , Issue.7 , pp. 677-686
    • Flores-Figueroa, E.1    Gutierrez-Espindola, G.2    Montesinos, J.J.3    Arana-Trejo, R.M.4    Mayani, H.5
  • 59
    • 0035283119 scopus 로고    scopus 로고
    • Vascular endothelial cell growth factor is an autocrine promoter of abnormal localized immature myeloid precursors and leukemia progenitor formation in myelodysplastic syndromes
    • Bellamy WT. Vascular endothelial cell growth factor is an autocrine promoter of abnormal localized immature myeloid precursors and leukemia progenitor formation in myelodysplastic syndromes. Blood. 2001;97(5):1427-1434.
    • (2001) Blood , vol.97 , Issue.5 , pp. 1427-1434
    • Bellamy, W.T.1
  • 60
    • 0036062374 scopus 로고    scopus 로고
    • Clinical relevance of vascular endothelial growth factor receptors 1 and 2 in acute myeloid leukaemia and myelodysplastic syndrome
    • Verstovsek S, Estey E, Manshouri T, et al. Clinical relevance of vascular endothelial growth factor receptors 1 and 2 in acute myeloid leukaemia and myelodysplastic syndrome. Br J Haematol. 2002;118(1): 151-156.
    • (2002) Br J Haematol , vol.118 , Issue.1 , pp. 151-156
    • Verstovsek, S.1    Estey, E.2    Manshouri, T.3
  • 61
    • 34047224675 scopus 로고    scopus 로고
    • Regulation of angiogenesis in the bone marrow of myelodysplastic syndromes transforming to overt leukaemia
    • Keith T, Araki Y, Ohyagi M, et al. Regulation of angiogenesis in the bone marrow of myelodysplastic syndromes transforming to overt leukaemia. Br J Haematol. 2007;137(3):206-215.
    • (2007) Br J Haematol , vol.137 , Issue.3 , pp. 206-215
    • Keith, T.1    Araki, Y.2    Ohyagi, M.3
  • 62
    • 33845992842 scopus 로고    scopus 로고
    • Reduced expression of inducible gelatinase B/matrix metalloproteinase-9 in monocytes from patients with myelodysplastic syndrome: Correlation of inducible levels with the percentage of cytogenetically marked cells and with marrow cellularity
    • Iwata M, Pillai M, Ramakrishnan A, et al. Reduced expression of inducible gelatinase B/matrix metalloproteinase-9 in monocytes from patients with myelodysplastic syndrome: Correlation of inducible levels with the percentage of cytogenetically marked cells and with marrow cellularity. Blood. 2007;109(1):85-92.
    • (2007) Blood , vol.109 , Issue.1 , pp. 85-92
    • Iwata, M.1    Pillai, M.2    Ramakrishnan, A.3
  • 63
    • 4644320261 scopus 로고    scopus 로고
    • Engraftment of distinct clonal MDS-derived hematopoietic precursors in NOD/SCID-beta2-microglobulin-deficient mice after intramedullary transplantation of hematopoietic and stromal cells
    • Kerbauy DM, Lesnikov V, Torok-Storb B, Bryant E, Deeg HJ. Engraftment of distinct clonal MDS-derived hematopoietic precursors in NOD/SCID-beta2-microglobulin-deficient mice after intramedullary transplantation of hematopoietic and stromal cells. Blood. 2004;104(7): 2202-2203.
    • (2004) Blood , vol.104 , Issue.7 , pp. 2202-2203
    • Kerbauy, D.M.1    Lesnikov, V.2    Torok-Storb, B.3    Bryant, E.4    Deeg, H.J.5
  • 64
    • 79953848179 scopus 로고    scopus 로고
    • Establishment of a xenograft model of human myelodysplastic syndromes
    • Muguruma Y, Matsushita H, Yahata T, et al. Establishment of a xenograft model of human myelodysplastic syndromes. Haematologica. 2011;96(4):543-551.
    • (2011) Haematologica , vol.96 , Issue.4 , pp. 543-551
    • Muguruma, Y.1    Matsushita, H.2    Yahata, T.3
  • 65
    • 0031930238 scopus 로고    scopus 로고
    • The human homolog of rat Jagged1 expressed by marrow stroma inhibits differentiation of 32D cells through interaction with Notch1
    • Li L, Milner LA, Deng Y, et al. The human homolog of rat Jagged1 expressed by marrow stroma inhibits differentiation of 32D cells through interaction with Notch1. Immunity. 1998;8(1):43-55.
    • (1998) Immunity , vol.8 , Issue.1 , pp. 43-55
    • Li, L.1    Milner, L.A.2    Deng, Y.3
  • 66
    • 84878331820 scopus 로고    scopus 로고
    • Effect of intravenous coadministration of human stroma cell lines on engraftment of long-term repopulating clonal myelodysplastic syndrome cells in immunodeficient mice
    • Li X, Marcondes AM, Ragoczy T, Telling A, Deeg HJ. Effect of intravenous coadministration of human stroma cell lines on engraftment of long-term repopulating clonal myelodysplastic syndrome cells in immunodeficient mice. Blood Cancer J. 2013;3:e113.
    • (2013) Blood Cancer J , vol.3 , pp. e113
    • Li, X.1    Marcondes, A.M.2    Ragoczy, T.3    Telling, A.4    Deeg, H.J.5
  • 67
    • 84873087237 scopus 로고    scopus 로고
    • CD146, a multi-functional molecule beyond adhesion
    • Wang Z, Yan X. CD146, a multi-functional molecule beyond adhesion. Cancer Lett. 2013;330(2):150-162.
    • (2013) Cancer Lett , vol.330 , Issue.2 , pp. 150-162
    • Wang, Z.1    Yan, X.2
  • 68
    • 35348921682 scopus 로고    scopus 로고
    • Self-renewing osteoprogenitors in bone marrow sinusoids can organize a hematopoietic microenvironment
    • Sacchetti B, Funari A, Michienzi S, et al. Self-renewing osteoprogenitors in bone marrow sinusoids can organize a hematopoietic microenvironment. Cell. 2007;131(2):324-336.
    • (2007) Cell , vol.131 , Issue.2 , pp. 324-336
    • Sacchetti, B.1    Funari, A.2    Michienzi, S.3
  • 69
    • 84890034242 scopus 로고    scopus 로고
    • Murine xenogeneic models of myelodysplastic syndrome: An essential role for stroma cells
    • Li X, Deeg HJ. Murine xenogeneic models of myelodysplastic syndrome: an essential role for stroma cells. Exp Hematol. 2014;42(1):4-10.
    • (2014) Exp Hematol , vol.42 , Issue.1 , pp. 4-10
    • Li, X.1    Deeg, H.J.2
  • 70
    • 84879452147 scopus 로고    scopus 로고
    • Perivascular support of human hematopoietic stem/progenitor cells
    • Corselli M, Chin CJ, Parekh C, et al. Perivascular support of human hematopoietic stem/progenitor cells. Blood. 2013;121(15):2891-2901.
    • (2013) Blood , vol.121 , Issue.15 , pp. 2891-2901
    • Corselli, M.1    Chin, C.J.2    Parekh, C.3
  • 71
    • 50849139576 scopus 로고    scopus 로고
    • A perivascular origin for mesenchymal stem cells in multiple human organs
    • Crisan M, Yap S, Casteilla L, et al. A perivascular origin for mesenchymal stem cells in multiple human organs. Cell Stem Cell. 2008;3(3):301-313.
    • (2008) Cell Stem Cell , vol.3 , Issue.3 , pp. 301-313
    • Crisan, M.1    Yap, S.2    Casteilla, L.3
  • 72
    • 84879442136 scopus 로고    scopus 로고
    • A niche in a dish: Pericytes support HSC
    • Levesque JP. A niche in a dish: pericytes support HSC. Blood. 2013;121(15):2816-2818.
    • (2013) Blood , vol.121 , Issue.15 , pp. 2816-2818
    • Levesque, J.P.1
  • 73
    • 84902200836 scopus 로고    scopus 로고
    • Myelodysplastic cells in patients reprogram mesenchymal stromal cells to establish a transplantable stem cell niche disease unit
    • Medyouf H, Mossner M, Jann JC, et al. Myelodysplastic cells in patients reprogram mesenchymal stromal cells to establish a transplantable stem cell niche disease unit. Cell Stem Cell. 2014;14(6):824-837.
    • (2014) Cell Stem Cell , vol.14 , Issue.6 , pp. 824-837
    • Medyouf, H.1    Mossner, M.2    Jann, J.C.3
  • 74
    • 84874320587 scopus 로고    scopus 로고
    • Prostaglandin E2 increases hematopoietic stem cell survival and accelerates hematopoietic recovery after radiation injury
    • Porter RL, Georger MA, Bromberg O, et al. Prostaglandin E2 increases hematopoietic stem cell survival and accelerates hematopoietic recovery after radiation injury. Stem Cells. 2013;31(2):372-383.
    • (2013) Stem Cells , vol.31 , Issue.2 , pp. 372-383
    • Porter, R.L.1    Georger, M.A.2    Bromberg, O.3
  • 75
    • 34547763216 scopus 로고    scopus 로고
    • Therapeutic targeting of a stem cell niche(vol 25, pg 238, 2007)
    • Adams GB, Martin RP, Alley IR, et al. Therapeutic targeting of a stem cell niche(vol 25, pg 238, 2007). Nat Biotechnol. 2007;25(8):944-944.
    • (2007) Nat Biotechnol , vol.25 , Issue.8 , pp. 944-944
    • Adams, G.B.1    Martin, R.P.2    Alley, I.R.3
  • 76
    • 84887424411 scopus 로고    scopus 로고
    • Differential regulation of myeloid leukemias by the bone marrow microenvironment
    • Krause DS, Fulzele K, Catic A, et al. Differential regulation of myeloid leukemias by the bone marrow microenvironment. Nat Med. 2013;19(11): 1513-1517.
    • (2013) Nat Med , vol.19 , Issue.11 , pp. 1513-1517
    • Krause, D.S.1    Fulzele, K.2    Catic, A.3
  • 77
    • 77955892943 scopus 로고    scopus 로고
    • Bone marrow graft-versus-host disease: Early destruction of hematopoietic niche after MHC-mismatched hematopoietic stem cell transplantation
    • Shono Y, Ueha S, Wang Y, et al. Bone marrow graft-versus-host disease: early destruction of hematopoietic niche after MHC-mismatched hematopoietic stem cell transplantation. Blood. 2010;115(26): 5401-5411.
    • (2010) Blood , vol.115 , Issue.26 , pp. 5401-5411
    • Shono, Y.1    Ueha, S.2    Wang, Y.3
  • 78
    • 84897019526 scopus 로고    scopus 로고
    • Loss of Asxl1 leads to myelodysplastic syndrome-like disease in mice
    • Wang J, Li Z, He Y, et al. Loss of Asxl1 leads to myelodysplastic syndrome-like disease in mice. Blood. 2014;123(4):541-553.
    • (2014) Blood , vol.123 , Issue.4 , pp. 541-553
    • Wang, J.1    Li, Z.2    He, Y.3
  • 79
    • 22044450619 scopus 로고    scopus 로고
    • NUP98-HOXD13 transgenic mice develop a highly penetrant, severe myelodysplastic syndrome that progresses to acute leukemia
    • Lin YW, Slape C, Zhang Z, Aplan PD. NUP98-HOXD13 transgenic mice develop a highly penetrant, severe myelodysplastic syndrome that progresses to acute leukemia. Blood. 2005;106(1):287-295.
    • (2005) Blood , vol.106 , Issue.1 , pp. 287-295
    • Lin, Y.W.1    Slape, C.2    Zhang, Z.3    Aplan, P.D.4


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