메뉴 건너뛰기




Volumn 364, Issue 9431, 2004, Pages 355-364

In-vivo dominant immune responses in aplastic anaemia: Molecular tracking of putatively pathogenetic T-cell clones by TCR β-CDR3 sequencing

Author keywords

[No Author keywords available]

Indexed keywords

ANTIGEN; CD8 ANTIGEN; T LYMPHOCYTE RECEPTOR BETA CHAIN;

EID: 3242782610     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(04)16724-X     Document Type: Article
Times cited : (216)

References (40)
  • 1
    • 0001126281 scopus 로고    scopus 로고
    • Aplastic anemia
    • N.S. Young. Philadelphia: WB Saunders
    • Young NS. Aplastic anemia. Young NS. The bone marrow failure syndromes. 2000;1-46 WB Saunders, Philadelphia
    • (2000) The Bone Marrow Failure Syndromes , pp. 1-46
    • Young, N.S.1
  • 2
    • 0030912049 scopus 로고    scopus 로고
    • The pathophysiology of acquired aplastic anemia
    • Young NS, Maciejewski J. The pathophysiology of acquired aplastic anemia. N Engl J Med. 336:1997;1365-1372
    • (1997) N Engl J Med , vol.336 , pp. 1365-1372
    • Young, N.S.1    MacIejewski, J.2
  • 3
    • 0033950194 scopus 로고    scopus 로고
    • Hematopoietic cell destruction by immune mechanisms in acquired aplastic anemia
    • Young NS. Hematopoietic cell destruction by immune mechanisms in acquired aplastic anemia. Semin Hematol. 37:2000;3-14
    • (2000) Semin Hematol , vol.37 , pp. 3-14
    • Young, N.S.1
  • 4
    • 0029016927 scopus 로고
    • Intensive immunosuppression with antithymocyte globulin and cyclosporine as treatment for severe acquired aplastic anemia
    • Rosenfeld SJ, Kimball J, Vining D, Young NS. Intensive immunosuppression with antithymocyte globulin and cyclosporine as treatment for severe acquired aplastic anemia. Blood. 85:1995;3058-3065
    • (1995) Blood , vol.85 , pp. 3058-3065
    • Rosenfeld, S.J.1    Kimball, J.2    Vining, D.3    Young, N.S.4
  • 5
    • 0035895062 scopus 로고    scopus 로고
    • Increased frequency of HLA-DR2 in patients with paroxysmal nocturnal hemoglobinuria and PNH/aplastic anemia syndrome
    • Maciejewski JP, Follman D, Rivera CE, Brown K, Simonis T, Young NS. Increased frequency of HLA-DR2 in patients with paroxysmal nocturnal hemoglobinuria and PNH/aplastic anemia syndrome. Blood. 98:2001;3513-3519
    • (2001) Blood , vol.98 , pp. 3513-3519
    • MacIejewski, J.P.1    Follman, D.2    Rivera, C.E.3    Brown, K.4    Simonis, T.5    Young, N.S.6
  • 6
    • 0029990271 scopus 로고    scopus 로고
    • Interferon-γ constitutively expressed in the stromal microenviroment of human marrow cultures mediates potent hematopoietic inhibition
    • Selleri C, Maciejewski JP, Sato T, Young NS. Interferon-γ constitutively expressed in the stromal microenviroment of human marrow cultures mediates potent hematopoietic inhibition. Blood. 87:1996;4149-4157
    • (1996) Blood , vol.87 , pp. 4149-4157
    • Selleri, C.1    MacIejewski, J.P.2    Sato, T.3    Young, N.S.4
  • 7
    • 0029048258 scopus 로고
    • Increased expression of Fas antigen on bone marrow CD34+ cells of patients with aplastic anaemia
    • Maciejewski JP, Selleri C, Sato T, Anderson S, Young NS. Increased expression of Fas antigen on bone marrow CD34+ cells of patients with aplastic anaemia. Br J Haematol. 91:1995;245-252
    • (1995) Br J Haematol , vol.91 , pp. 245-252
    • MacIejewski, J.P.1    Selleri, C.2    Sato, T.3    Anderson, S.4    Young, N.S.5
  • 8
    • 0022006029 scopus 로고
    • Circulating activated suppressor T lymphocytes in aplastic anemia
    • Zoumbos N, Gascon P, Trost S, Djeu J, Young N. Circulating activated suppressor T lymphocytes in aplastic anemia. N Engl J Med. 312:1985;257-265
    • (1985) N Engl J Med , vol.312 , pp. 257-265
    • Zoumbos, N.1    Gascon, P.2    Trost, S.3    Djeu, J.4    Young, N.5
  • 9
    • 0030962277 scopus 로고    scopus 로고
    • Isolation of a T-cell clone showing HLA-DRB1*0405-restricted cytotoxicity for hematopoietic cells in a patient with aplastic anemia
    • Nakao S, Takami A, Takamatsu H, et al. Isolation of a T-cell clone showing HLA-DRB1*0405-restricted cytotoxicity for hematopoietic cells in a patient with aplastic anemia. Blood. 89:1997;3691-3699
    • (1997) Blood , vol.89 , pp. 3691-3699
    • Nakao, S.1    Takami, A.2    Takamatsu, H.3
  • 11
    • 0029014308 scopus 로고
    • T-cell repertoires in healthy and diseased human tissues analysed by T-cell receptor β-chain CDR3 size determination: Evidence for oligoclonal expansions in tumours and inflammatory diseases
    • Even J, Lim A, Puisieux I, et al. T-cell repertoires in healthy and diseased human tissues analysed by T-cell receptor β-chain CDR3 size determination: evidence for oligoclonal expansions in tumours and inflammatory diseases. Res Immunol. 146:1995;65-80
    • (1995) Res Immunol , vol.146 , pp. 65-80
    • Even, J.1    Lim, A.2    Puisieux, I.3
  • 12
    • 0022579722 scopus 로고
    • The molecular genetics of the T-cell antigen receptor and T-cell antigen recognition
    • Kronenberg M, Siu G, Hood LE, Shastri N. The molecular genetics of the T-cell antigen receptor and T-cell antigen recognition. Annu Rev Immunol. 4:1986;529-591
    • (1986) Annu Rev Immunol , vol.4 , pp. 529-591
    • Kronenberg, M.1    Siu, G.2    Hood, L.E.3    Shastri, N.4
  • 13
    • 0033568626 scopus 로고    scopus 로고
    • A common TCR V-D-J sequence in Vβ13.1 T cells recognizing an immunodominant peptide of myelin basic protein in multiple sclerosis
    • Hong J, Zang YCQ, Tejada-Simon MV, et al. A common TCR V-D-J sequence in Vβ13.1 T cells recognizing an immunodominant peptide of myelin basic protein in multiple sclerosis. J Immunol. 163:1999;3530-3538
    • (1999) J Immunol , vol.163 , pp. 3530-3538
    • Hong, J.1    Zang, Y.C.Q.2    Tejada-Simon, M.V.3
  • 14
    • 0037092948 scopus 로고    scopus 로고
    • Changes in T-cell receptor VB repertoire in aplastic anemia: Effects of different immunosuppressive regimens
    • Kook H, Risitano AM, Zeng W, et al. Changes in T-cell receptor VB repertoire in aplastic anemia: effects of different immunosuppressive regimens. Blood. 99:2002;3668-3675
    • (2002) Blood , vol.99 , pp. 3668-3675
    • Kook, H.1    Risitano, A.M.2    Zeng, W.3
  • 15
    • 0036660175 scopus 로고    scopus 로고
    • Oligoclonal and polyclonal CD4 and CD8 lymphocytes in aplastic anemia and paroxysmal nocturnal hemoglobinuria measured by Vβ CDR3 spectratyping and flow cytometry
    • Risitano AM, Kook H, Zeng W, Chen G, Young NS, Maciejewski JP. Oligoclonal and polyclonal CD4 and CD8 lymphocytes in aplastic anemia and paroxysmal nocturnal hemoglobinuria measured by Vβ CDR3 spectratyping and flow cytometry. Blood. 100:2002;178-183
    • (2002) Blood , vol.100 , pp. 178-183
    • Risitano, A.M.1    Kook, H.2    Zeng, W.3    Chen, G.4    Young, N.S.5    MacIejewski, J.P.6
  • 16
    • 0038541649 scopus 로고    scopus 로고
    • Application of the molecular analysis of the T-cell receptor repertoire in the study of immune-mediated hematologic diseases
    • Plasilova M, Risitano A, Maciejewski JP. Application of the molecular analysis of the T-cell receptor repertoire in the study of immune-mediated hematologic diseases. Hematology. 8:2003;173-181
    • (2003) Hematology , vol.8 , pp. 173-181
    • Plasilova, M.1    Risitano, A.2    MacIejewski, J.P.3
  • 17
    • 0034793917 scopus 로고    scopus 로고
    • Limited heterogeneity of T-cell receptor Vβ usage in aplastic anemia
    • Zeng W, Maciejewski JP, Chen G, Young NS. Limited heterogeneity of T-cell receptor Vβ usage in aplastic anemia. J Clin Invest. 108:2001;765-773I
    • (2001) J Clin Invest , vol.108
    • Zeng, W.1    MacIejewski, J.P.2    Chen, G.3    Young, N.S.4
  • 18
    • 0023576003 scopus 로고
    • Incidence of aplastic anemia: The relevance of diagnostic criteria
    • International Agranulocytosis and Aplastic Anemia Study. Incidence of aplastic anemia: the relevance of diagnostic criteria. Blood. 70:1987;1718-1723
    • (1987) Blood , vol.70 , pp. 1718-1723
  • 19
    • 0033592318 scopus 로고    scopus 로고
    • Paroxysmal nocturnal hemoglobinuria cells in patients with bone marrow failure syndromes
    • Dunn DE, Tannawattanacharoen P, Boccuni P, et al. Paroxysmal nocturnal hemoglobinuria cells in patients with bone marrow failure syndromes. Ann Intern Med. 131:1999;401-408
    • (1999) Ann Intern Med , vol.131 , pp. 401-408
    • Dunn, D.E.1    Tannawattanacharoen, P.2    Boccuni, P.3
  • 20
    • 0036173941 scopus 로고    scopus 로고
    • Visualization and quantification of T cell-mediated cytotoxicity using cell-permeable fluorogenic caspase substrates
    • Liu L, Chahroudi A, Silvestri G, et al. Visualization and quantification of T cell-mediated cytotoxicity using cell-permeable fluorogenic caspase substrates. Nat Med. 8:2002;185-189
    • (2002) Nat Med , vol.8 , pp. 185-189
    • Liu, L.1    Chahroudi, A.2    Silvestri, G.3
  • 21
    • 0034255328 scopus 로고    scopus 로고
    • Flow cytometric analysis of the Vbeta repertoire in healthy controls
    • van den Beemd R, Boor PP, van Lochem EG, et al. Flow cytometric analysis of the Vbeta repertoire in healthy controls. Cytometry. 40:2000;336-345
    • (2000) Cytometry , vol.40 , pp. 336-345
    • Van Den Beemd, R.1    Boor, P.P.2    Van Lochem, E.G.3
  • 22
    • 0037103384 scopus 로고    scopus 로고
    • Intracellular interferon-gamma in circulating and marrow T cells detected by flow cytometry and the response to immunosuppressive therapy in aplastic anemia patients
    • Sloand E, Kim S, Maciejewski JP, Tisdale J, Follman D, Young NS. Intracellular interferon-gamma in circulating and marrow T cells detected by flow cytometry and the response to immunosuppressive therapy in aplastic anemia patients. Blood. 100:2002;1185-1191
    • (2002) Blood , vol.100 , pp. 1185-1191
    • Sloand, E.1    Kim, S.2    MacIejewski, J.P.3    Tisdale, J.4    Follman, D.5    Young, N.S.6
  • 23
    • 0037228871 scopus 로고    scopus 로고
    • Molecular tracking of antigen-specific T cell clones in neurological immune-mediated disorders
    • Muraro PA, Wandinger KP, Bielekova B, et al. Molecular tracking of antigen-specific T cell clones in neurological immune-mediated disorders. Brain. 126:2003;20-31
    • (2003) Brain , vol.126 , pp. 20-31
    • Muraro, P.A.1    Wandinger, K.P.2    Bielekova, B.3
  • 24
    • 0034618094 scopus 로고    scopus 로고
    • Clonal expansions of CD8(+) T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction
    • Babbe H, Roers A, Waisman A, et al. Clonal expansions of CD8(+) T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction. J Exp Med. 192:2000;393-404
    • (2000) J Exp Med , vol.192 , pp. 393-404
    • Babbe, H.1    Roers, A.2    Waisman, A.3
  • 25
    • 0037388305 scopus 로고    scopus 로고
    • Clonal tracking of autoaggressive T cells in polymoyositis by combining laser microdissection, single-cell PCR, and CDR3-spectratype analysis
    • Hofbauer M, Wiesener S, Babbe H, et al. Clonal tracking of autoaggressive T cells in polymoyositis by combining laser microdissection, single-cell PCR, and CDR3-spectratype analysis. Proc Natl Acad Sci USA. 100:2003;4090-4095
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 4090-4095
    • Hofbauer, M.1    Wiesener, S.2    Babbe, H.3
  • 26
    • 0037417974 scopus 로고    scopus 로고
    • Definitive separation of graft-versus-leukemia-and graft-versus-host- specific CD4+ T cells by virture of their receptor beta loci sequences
    • Michalek J, Collins RH, Durrani HP, et al. Definitive separation of graft-versus-leukemia-and graft-versus-host-specific CD4+ T cells by virture of their receptor beta loci sequences. Proc Natl Acad Sci USA. 100:2003;1180-1184
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 1180-1184
    • Michalek, J.1    Collins, R.H.2    Durrani, H.P.3
  • 27
    • 0037420493 scopus 로고    scopus 로고
    • Identification and monitoring of graft-versus-host specific T-cell clone in stem-cell transplantation
    • Michalek J, Collins RH, Hill BJ, Brenchley JM, Douek DC. Identification and monitoring of graft-versus-host specific T-cell clone in stem-cell transplantation. Lancet. 361:2003;1183-1185
    • (2003) Lancet , vol.361 , pp. 1183-1185
    • Michalek, J.1    Collins, R.H.2    Hill, B.J.3    Brenchley, J.M.4    Douek, D.C.5
  • 28
    • 0032985551 scopus 로고    scopus 로고
    • Frequent enrichment for CD8 T cells reactive against common herpes viruses in chronic inflammatory lesions: Towards a reassessment of the physiopathological significance of T cell clonal expansions found in autoimmune inflammatory processes
    • Scotet E, Peyrat MA, Saulquin X, et al. Frequent enrichment for CD8 T cells reactive against common herpes viruses in chronic inflammatory lesions: towards a reassessment of the physiopathological significance of T cell clonal expansions found in autoimmune inflammatory processes. Eur J Immunol. 29:1999;973-985
    • (1999) Eur J Immunol , vol.29 , pp. 973-985
    • Scotet, E.1    Peyrat, M.A.2    Saulquin, X.3
  • 29
    • 0034782479 scopus 로고    scopus 로고
    • Oligoclonal T cell expansion in myelodysplastic syndrome: Evidence for an autoimmune process
    • Epperson DE, Nakamura R, Saunthararajah Y, Melenhorst J, Barrett AJ. Oligoclonal T cell expansion in myelodysplastic syndrome: evidence for an autoimmune process. Leuk Res. 25:2001;1075-1083
    • (2001) Leuk Res , vol.25 , pp. 1075-1083
    • Epperson, D.E.1    Nakamura, R.2    Saunthararajah, Y.3    Melenhorst, J.4    Barrett, A.J.5
  • 30
    • 1642443895 scopus 로고    scopus 로고
    • Molecular analysis of T cell receptor clonotypes in LGL: A clonal model for polyclonal responses
    • O'Keefe C, Plasilova M, Risitano AM, et al. Molecular analysis of T cell receptor clonotypes in LGL: a clonal model for polyclonal responses. J Immunol. 172:2004;1960-1969
    • (2004) J Immunol , vol.172 , pp. 1960-1969
    • O'Keefe, C.1    Plasilova, M.2    Risitano, A.M.3
  • 31
    • 0034307521 scopus 로고    scopus 로고
    • Abnormal T-cell repertoire is consistent with immune process underlying the pathogenesis of paroxysmal nocturnal hemoglobinuria
    • Karadimitris A, Manavian JS, Thaler HT, et al. Abnormal T-cell repertoire is consistent with immune process underlying the pathogenesis of paroxysmal nocturnal hemoglobinuria. Blood. 96:2000;2613-2620
    • (2000) Blood , vol.96 , pp. 2613-2620
    • Karadimitris, A.1    Manavian, J.S.2    Thaler, H.T.3
  • 32
    • 0037111548 scopus 로고    scopus 로고
    • Loss of T-lymphocyte clonal dominance in patients with myelodysplastic syndrome responsive to immunosuppression
    • Kochenderfer JN, Kobayashi S, Wieder ED, Su C, Molldrem JJ. Loss of T-lymphocyte clonal dominance in patients with myelodysplastic syndrome responsive to immunosuppression. Blood. 100:2002;3639-3645
    • (2002) Blood , vol.100 , pp. 3639-3645
    • Kochenderfer, J.N.1    Kobayashi, S.2    Wieder, E.D.3    Su, C.4    Molldrem, J.J.5
  • 33
    • 0028926223 scopus 로고
    • Molecular mimicry in T cell-mediated autoimmunity: Viral peptides activate human T cell clones specific for myelin basic protein
    • Wucherpfennig KW, Strominger JL. Molecular mimicry in T cell-mediated autoimmunity: viral peptides activate human T cell clones specific for myelin basic protein. Cell. 80:1995;695-705
    • (1995) Cell , vol.80 , pp. 695-705
    • Wucherpfennig, K.W.1    Strominger, J.L.2
  • 34
    • 0036793245 scopus 로고    scopus 로고
    • A functional and structural basis for TCR cross-reactivity in multiple sclerosis
    • Lang HL, Jacobsen H, Ikemizu S, et al. A functional and structural basis for TCR cross-reactivity in multiple sclerosis. Nat Immunol. 3:2002;940-943
    • (2002) Nat Immunol , vol.3 , pp. 940-943
    • Lang, H.L.1    Jacobsen, H.2    Ikemizu, S.3
  • 35
    • 0028783395 scopus 로고
    • T cell receptor repertoire for a viral epitope in humans is diversified by tolerance to a background major histocompatibility complex antigen
    • Burrows SR, Silins SL, Moss DJ, Khanna R, Misko IS, Argaet VP. T cell receptor repertoire for a viral epitope in humans is diversified by tolerance to a background major histocompatibility complex antigen. J Exp Med. 182:1995;1703-1715
    • (1995) J Exp Med , vol.182 , pp. 1703-1715
    • Burrows, S.R.1    Silins, S.L.2    Moss, D.J.3    Khanna, R.4    Misko, I.S.5    Argaet, V.P.6
  • 36
    • 12244285714 scopus 로고    scopus 로고
    • Clonotype tracking of TCR repertoires during chronic virus infections
    • Cohen GB, Islam SA, Noble MS, et al. Clonotype tracking of TCR repertoires during chronic virus infections. Virology. 304:2002;474-484
    • (2002) Virology , vol.304 , pp. 474-484
    • Cohen, G.B.1    Islam, S.A.2    Noble, M.S.3
  • 37
    • 0034664023 scopus 로고    scopus 로고
    • Frequent contribution of T cell clonotypes with public TCR features to the chronic response against a dominant EBV-derived epitope: Application to direct detention of their molecular imprint on the human peripheral T cell repertoire
    • Lim A, Trautmann L, Peyrat MA, et al. Frequent contribution of T cell clonotypes with public TCR features to the chronic response against a dominant EBV-derived epitope: application to direct detention of their molecular imprint on the human peripheral T cell repertoire. J Immunol. 165:2000;2001-2011
    • (2000) J Immunol , vol.165 , pp. 2001-2011
    • Lim, A.1    Trautmann, L.2    Peyrat, M.A.3
  • 38
    • 10744231635 scopus 로고    scopus 로고
    • Autoantibodies frequently detected in patients with aplastic anemia
    • Hirano N, Butler MO, Von Bergwelt-Baildon MS, et al. Autoantibodies frequently detected in patients with aplastic anemia. Blood. 102:2003;4567-4575
    • (2003) Blood , vol.102 , pp. 4567-4575
    • Hirano, N.1    Butler, M.O.2    Von Bergwelt-Baildon, M.S.3
  • 39
    • 25944471796 scopus 로고    scopus 로고
    • Diazepam-binding inhibitor related sequence-1 (DRS-1) candidate autoantigen in acquired aplastic anemia
    • (abstr).
    • Feng X, Tatsuya C, Takeharo K, et al. Diazepam-binding inhibitor related sequence-1 (DRS-1) candidate autoantigen in acquired aplastic anemia. Blood 2003; 102: 206a (abstr).
    • (2003) Blood , vol.102
    • Feng, X.1    Tatsuya, C.2    Takeharo, K.3
  • 40
    • 0344059131 scopus 로고    scopus 로고
    • Use of combinatorial peptide libraries for T-cell epitope mapping
    • Sospedra M, Pinilla C, Martin R. Use of combinatorial peptide libraries for T-cell epitope mapping. Methods. 29:2003;236-247
    • (2003) Methods , vol.29 , pp. 236-247
    • Sospedra, M.1    Pinilla, C.2    Martin, R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.