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Volumn 98, Issue 11, 2013, Pages 1677-1685

Mesenchymal stromal cells from patients with myelodyplastic syndrome display distinct functional alterations that are modulated by lenalidomide

Author keywords

[No Author keywords available]

Indexed keywords

5' NUCLEOTIDASE; ACTIVATED LEUKOCYTE CELL ADHESION MOLECULE; ANGIOPOIETIN 1; BETA1 INTEGRIN; CD146 ANTIGEN; CD34 ANTIGEN; CELL ADHESION MOLECULE; CHEMOKINE RECEPTOR CXCR4; ENDOGLIN; IMID; LENALIDOMIDE; STEM CELL FACTOR; STROMAL CELL DERIVED FACTOR 1ALPHA; THY 1 ANTIGEN; UNCLASSIFIED DRUG;

EID: 84886998745     PISSN: 03906078     EISSN: 15928721     Source Type: Journal    
DOI: 10.3324/haematol.2013.083972     Document Type: Article
Times cited : (77)

References (50)
  • 1
    • 84868193421 scopus 로고    scopus 로고
    • The classification of MDS: From FAB to WHO and beyond
    • Vardiman J. The classification of MDS: from FAB to WHO and beyond. Leuk Res. 2012; 36(12): 1453-8.
    • (2012) Leuk Res , vol.36 , Issue.12 , pp. 1453-1458
    • Vardiman, J.1
  • 2
    • 46749151451 scopus 로고    scopus 로고
    • Myelodysplastic syndromes
    • Nimer SD. Myelodysplastic syndromes. Blood. 2008; 111(10): 4841-51.
    • (2008) Blood , vol.111 , Issue.10 , pp. 4841-4851
    • Nimer, S.D.1
  • 3
    • 79952164235 scopus 로고    scopus 로고
    • Unraveling the molecular pathophysiology of myelodysplastic syndromes
    • BejarR, Levine R, Ebert BL. Unraveling the molecular pathophysiology of myelodysplastic syndromes. J Clin Oncol. 2011; 29(5): 504-15.
    • (2011) J Clin Oncol , vol.29 , Issue.5 , pp. 504-515
    • Bejar, R.1    Levine, R.2    Ebert, B.L.3
  • 4
    • 33749438404 scopus 로고    scopus 로고
    • Myelodysplastic Syndrome-003 Study Investigators. Lenalidomide in the myelodysplastic syndrome with chromosome 5q deletion
    • List A, Dewald G, Bennett J, Giagounidis A, Raza A, Feldman E, et al. Myelodysplastic Syndrome-003 Study Investigators. Lenalidomide in the myelodysplastic syndrome with chromosome 5q deletion. N Engl J Med. 2006; 355(14): 1456-65.
    • (2006) N Engl J Med , vol.355 , Issue.14 , pp. 1456-1465
    • List, A.1    Dewald, G.2    Bennett, J.3    Giagounidis, A.4    Raza, A.5    Feldman, E.6
  • 5
    • 38049113182 scopus 로고    scopus 로고
    • Phase 2 study of lenalidomide in transfusion-dependent, lowrisk, and intermediate-1 risk myelodysplastic syndromes with karyotypes other than deletion 5q
    • Raza A, Reeves JA, Feldman EJ, Dewald GW, Bennet JM, Deeg HJ, et al. Phase 2 study of lenalidomide in transfusion-dependent, lowrisk, and intermediate-1 risk myelodysplastic syndromes with karyotypes other than deletion 5q. Blood. 2008; 111(1): 86-93.
    • (2008) Blood , vol.111 , Issue.1 , pp. 86-93
    • Raza, A.1    Reeves, J.A.2    Feldman, E.J.3    Dewald, G.W.4    Bennet, J.M.5    Deeg, H.J.6
  • 6
    • 80053984917 scopus 로고    scopus 로고
    • Disease progression mechanism in myelodysplastic syndromes: Insight into the role of the microenvironment
    • Ishibashi M, Tamura H, Ogata K. Disease progression mechanism in myelodysplastic syndromes: insight into the role of the microenvironment. Leuk Res. 2011; 35(11): 1449-52.
    • (2011) Leuk Res , vol.35 , Issue.11 , pp. 1449-1452
    • Ishibashi, M.1    Tamura, H.2    Ogata, K.3
  • 7
    • 84880968072 scopus 로고    scopus 로고
    • The biology of myelodysplastic syndromes: Unity despite heterogeneity
    • Raza A, Cruz R, Latif T, Mukherjee S, Galili N. The biology of myelodysplastic syndromes: unity despite heterogeneity. Hematol Rep. 2010; 2(1): e4.
    • (2010) Hematol Rep , vol.2 , Issue.1
    • Raza, A.1    Cruz, R.2    Latif, T.3    Mukherjee, S.4    Galili, N.5
  • 8
    • 79959959625 scopus 로고    scopus 로고
    • Niche contributions to oncogenesis: Emerging concepts and implications for the hematopoietic system
    • Raaijmakers MH. Niche contributions to oncogenesis: emerging concepts and implications for the hematopoietic system. Haematologica. 2011; 96(7): 1041-8.
    • (2011) Haematologica , vol.96 , Issue.7 , pp. 1041-1048
    • Raaijmakers, M.H.1
  • 9
    • 33646428091 scopus 로고    scopus 로고
    • Normal stem cells and cancer stem cells: The niche matters
    • Li L, Neaves WB. Normal stem cells and cancer stem cells: the niche matters. Cancer Res. 2006; S 66(9): 4553-7.
    • (2006) Cancer Res. S , vol.66 , Issue.9 , pp. 4553-4557
    • Li, L.1    Neaves, W.B.2
  • 10
    • 77950862042 scopus 로고    scopus 로고
    • Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia
    • Raaijmakers MH, Mukherjee S, Guo S, Zhang S, Kobayash T, Schoonmaker JA, et al. Bone progenitor dysfunction induces myelodysplasia and secondary leukaemia. Nature. 2010; 464(7290): 852-7.
    • (2010) Nature , vol.464 , Issue.7290 , pp. 852-857
    • Raaijmakers, M.H.1    Mukherjee, S.2    Guo, S.3    Zhang, S.4    Kobayash, T.5    Schoonmaker, J.A.6
  • 11
    • 34250331610 scopus 로고    scopus 로고
    • A microenvironment-induced myeloproliferative syndrome caused by retinoic acid receptor gamma deficiency
    • Walkley CR, Olsen GH, Dworkin S, Fabb SA, Swann J, McArthur GA, et al. A microenvironment-induced myeloproliferative syndrome caused by retinoic acid receptor gamma deficiency. Cell. 2007; 129(6): 1097-110.
    • (2007) Cell , vol.129 , Issue.6 , pp. 1097-1110
    • Walkley, C.R.1    Olsen, G.H.2    Dworkin, S.3    Fabb, S.A.4    Swann, J.5    McArthur, G.A.6
  • 12
    • 0036236860 scopus 로고    scopus 로고
    • Marrow stroma in MDS: Culprit or bystander?
    • Deeg HJ. Marrow stroma in MDS: culprit or bystander? Leuk Res. 2002; 26(7): 687-8.
    • (2002) Leuk Res , vol.26 , Issue.7 , pp. 687-688
    • Deeg, H.J.1
  • 13
    • 77957020167 scopus 로고    scopus 로고
    • The essential functions of adipo-osteogenic progenitors as the hematopoietic stem and progenitor cell niche
    • Omatsu Y, Sugiyama T, Kohara H, Kondoh G, Fujii N, Kohno K, et al. The essential functions of adipo-osteogenic progenitors as the hematopoietic stem and progenitor cell niche. Immunity. 2010; 33(3): 387-99.
    • (2010) Immunity , vol.33 , Issue.3 , pp. 387-399
    • Omatsu, Y.1    Sugiyama, T.2    Kohara, H.3    Kondoh, G.4    Fujii, N.5    Kohno, K.6
  • 15
    • 81355147381 scopus 로고    scopus 로고
    • The hematopoietic stem cell niche at a glance
    • Lo Celso C, Scadden DT. The hematopoietic stem cell niche at a glance. J Cell Sci. 2011; 124: 3529-35.
    • (2011) J Cell Sci , vol.124 , pp. 3529-3535
    • Lo Celso, C.1    Scadden, D.T.2
  • 16
    • 77952923309 scopus 로고    scopus 로고
    • Immunomodulatory properties of mesenchymal stromal cells and their therapeutic consequences for immune-mediated disorders
    • Zhao S, Wehner R, Bornhäuser M, Wassmuth R, Bachmann M, Schmitz M. Immunomodulatory properties of mesenchymal stromal cells and their therapeutic consequences for immune-mediated disorders. Stem Cells Dev. 2010; 19(5): 607-14.
    • (2010) Stem Cells Dev , vol.19 , Issue.5 , pp. 607-614
    • Zhao, S.1    Wehner, R.2    Bornhäuser, M.3    Wassmuth, R.4    Bachmann, M.5    Schmitz, M.6
  • 17
    • 84866707729 scopus 로고    scopus 로고
    • The different immunoregulatory functions of mesenchymal stem cells in patients with lowrisk or high-risk myelodysplastic syndromes
    • Zhao Z, Wang Z, Li Q, Li W, You Y, Zou P. The different immunoregulatory functions of mesenchymal stem cells in patients with lowrisk or high-risk myelodysplastic syndromes. PLoS One. 2012; 7(9): e45675.
    • (2012) PLoS One , vol.7 , Issue.9
    • Zhao, Z.1    Wang, Z.2    Li, Q.3    Li, W.4    You, Y.5    Zou, P.6
  • 18
    • 84866324411 scopus 로고    scopus 로고
    • Impact of lenalidomide on the functional properties of human mesenchymal stromal cells
    • Wobus M, Benath G, Ferrer RA, Wehner R, Schmitz M, Hofbauer LC, et al. Impact of lenalidomide on the functional properties of human mesenchymal stromal cells. Exp Hematol. 2012; 40(10): 867-76.
    • (2012) Exp Hematol , vol.40 , Issue.10 , pp. 867-876
    • Wobus, M.1    Benath, G.2    Ferrer, R.A.3    Wehner, R.4    Schmitz, M.5    Hofbauer, L.C.6
  • 19
    • 35448934364 scopus 로고    scopus 로고
    • Apoptosis and antiapoptotic mechanisms in the progression of myelodysplastic syndrome
    • Kerbauy DB, Deeg HJ. Apoptosis and antiapoptotic mechanisms in the progression of myelodysplastic syndrome. Exp Hematol. 2007; 35(11): 1739-46.
    • (2007) Exp Hematol , vol.35 , Issue.11 , pp. 1739-1746
    • Kerbauy, D.B.1    Deeg, H.J.2
  • 20
    • 20944442426 scopus 로고    scopus 로고
    • Mesenchymal cells generated from patients with myelodysplastic syndromes are devoid of chromosomal clonal markers and support short-and long-term hematopoiesis in vitro
    • Soenen-Cornu V, Tourino C, Bonnet ML, Guillier M, Flamant S, Kotb R, et al. Mesenchymal cells generated from patients with myelodysplastic syndromes are devoid of chromosomal clonal markers and support short-and long-term hematopoiesis in vitro. Oncogene. 2005; 24(15): 2441-8.
    • (2005) Oncogene , vol.24 , Issue.15 , pp. 2441-2448
    • Soenen-Cornu, V.1    Tourino, C.2    Bonnet, M.L.3    Guillier, M.4    Flamant, S.5    Kotb, R.6
  • 21
    • 68349128436 scopus 로고    scopus 로고
    • Human mesenchymal stem cells self-renew and differentiate according to a deterministic hierarchy
    • Sarugaser R, Hanoun L, Keating A, Stanford WL, Davies JE. Human mesenchymal stem cells self-renew and differentiate according to a deterministic hierarchy. PLoS One. 2009; 4 (8): e6498.
    • (2009) PLoS One , vol.4 , Issue.8
    • Sarugaser, R.1    Hanoun, L.2    Keating, A.3    Stanford, W.L.4    Davies, J.E.5
  • 22
    • 77954928083 scopus 로고    scopus 로고
    • Reserves, functional, immunoregulatory, and cytogenetic properties of bone marrow mesenchymal stem cells in patients with myelodysplastic syndromes
    • Klaus M, Stavroulaki E, Kastrinaki MC, Fragioudaki P, Giannikou K, Psyllaki M, et al. Reserves, functional, immunoregulatory, and cytogenetic properties of bone marrow mesenchymal stem cells in patients with myelodysplastic syndromes. Stem Cells Dev. 2010; 19(7): 1043-54.
    • (2010) Stem Cells Dev , vol.19 , Issue.7 , pp. 1043-1054
    • Klaus, M.1    Stavroulaki, E.2    Kastrinaki, M.C.3    Fragioudaki, P.4    Giannikou, K.5    Psyllaki, M.6
  • 24
    • 64849104318 scopus 로고    scopus 로고
    • Both expanded and uncultured mesenchymal stem cells from MDS patients are genomically abnormal, showing a specific genetic profile for the 5q-syndrome
    • Lopez-Villar O, Garcia JL, Sanchez-Guijo FM, Robledo C, Villaron EM, Hernández-Campo P, et al. Both expanded and uncultured mesenchymal stem cells from MDS patients are genomically abnormal, showing a specific genetic profile for the 5q-syndrome. Leukemia. 2009; 23(4): 664-72.
    • (2009) Leukemia , vol.23 , Issue.4 , pp. 664-672
    • Lopez-Villar, O.1    Garcia, J.L.2    Sanchez-Guijo, F.M.3    Robledo, C.4    Villaron, E.M.5    Hernández-Campo, P.6
  • 25
    • 39649091183 scopus 로고    scopus 로고
    • Inappropriate Notch activity and limited mesenchymal stem cell plasticity in the bone marrow of patients with myelodysplastic syndromes
    • Varga G, Kiss J, Várkonyi J, Vas V, Farkas P, Pálóczi K, Uher F. Inappropriate Notch activity and limited mesenchymal stem cell plasticity in the bone marrow of patients with myelodysplastic syndromes. Pathol Oncol Res. 2007; 13(4): 311-9.
    • (2007) Pathol Oncol Res , vol.13 , Issue.4 , pp. 311-319
    • Varga, G.1    Kiss, J.2    Várkonyi, J.3    Vas, V.4    Farkas, P.5    Pálóczi, K.6    Uher, F.7
  • 26
    • 84862861535 scopus 로고    scopus 로고
    • Intrinsic growth deficiencies of mesenchymal stromal cells in myelodysplastic syndromes
    • Aanei CM, Flandrin P, Eloae FZ, Carasevici E, Guyotat D, Wattel E, et al. Intrinsic growth deficiencies of mesenchymal stromal cells in myelodysplastic syndromes. Stem Cells Dev. 2012; 21(10): 1604-15.
    • (2012) Stem Cells Dev , vol.21 , Issue.10 , pp. 1604-1615
    • Aanei, C.M.1    Flandrin, P.2    Eloae, F.Z.3    Carasevici, E.4    Guyotat, D.5    Wattel, E.6
  • 28
    • 38649108162 scopus 로고    scopus 로고
    • Human bone marrow mesenchymal stem cells in vivo
    • Jones E, McGonagle D. Human bone marrow mesenchymal stem cells in vivo. Rheumatology (Oxford). 2008; 47(2): 126-31.
    • (2008) Rheumatology (Oxford) , vol.47 , Issue.2 , pp. 126-131
    • Jones, E.1    McGonagle, D.2
  • 29
    • 78650966081 scopus 로고    scopus 로고
    • Markers distinguishing mesenchymal stem cells from fibroblasts are downregulated with passaging
    • Halfon S, Abramov N, Grinblat B, Ginis I. Markers distinguishing mesenchymal stem cells from fibroblasts are downregulated with passaging. Stem Cells Dev. 2011; 20 (1): 53-66.
    • (2011) Stem Cells Dev , vol.20 , Issue.1 , pp. 53-66
    • Halfon, S.1    Abramov, N.2    Grinblat, B.3    Ginis, I.4
  • 30
    • 33645392228 scopus 로고    scopus 로고
    • Immunophenotypic heterogeneity of bone marrow-derived mesenchymal stromal cells from patients with hematologic disorders: Correlation with bone marrow microenvironment
    • Campioni D, Moretti S, Ferrari L, Punturieri M, Castoldi GL, Lanza F. Immunophenotypic heterogeneity of bone marrow-derived mesenchymal stromal cells from patients with hematologic disorders: correlation with bone marrow microenvironment. Haematologica. 2006; 91(3): 364-8.
    • (2006) Haematologica , vol.91 , Issue.3 , pp. 364-368
    • Campioni, D.1    Moretti, S.2    Ferrari, L.3    Punturieri, M.4    Castoldi, G.L.5    Lanza, F.6
  • 32
    • 0033915528 scopus 로고    scopus 로고
    • Hematopoietic stem cell transplantation in patients with myelodysplastic syndrome
    • Deeg HJ, Appelbaum FR. Hematopoietic stem cell transplantation in patients with myelodysplastic syndrome. Leuk Res. 2000; 24(8): 653-63.
    • (2000) Leuk Res , vol.24 , Issue.8 , pp. 653-663
    • Deeg, H.J.1    Appelbaum, F.R.2
  • 33
    • 0034022396 scopus 로고    scopus 로고
    • Negative regulators of hemopoiesis and stroma function in patients with myelodysplastic syndrome
    • Deeg HJ, Beckham C, Loken MR, Bryant E, Lesnikova M, Shulman HM, et al. Negative regulators of hemopoiesis and stroma function in patients with myelodysplastic syndrome. Leuk Lymphoma. 2000; 37(3-4): 405-14.
    • (2000) Leuk Lymphoma , vol.37 , Issue.3-4 , pp. 405-414
    • Deeg, H.J.1    Beckham, C.2    Loken, M.R.3    Bryant, E.4    Lesnikova, M.5    Shulman, H.M.6
  • 34
    • 57849108116 scopus 로고    scopus 로고
    • Leukemic cells create bone marrow niches that disrupt the behavior of normal hematopoietic progenitor cells
    • Colmone A, Amorim M, Pontier AL, Wang S, Jablonski E, Sipkins DA. Leukemic cells create bone marrow niches that disrupt the behavior of normal hematopoietic progenitor cells. Science. 2008; 322(5909): 1861-5.
    • (2008) Science , vol.322 , Issue.5909 , pp. 1861-1865
    • Colmone, A.1    Amorim, M.2    Pontier, A.L.3    Wang, S.4    Jablonski, E.5    Sipkins, D.A.6
  • 35
    • 78751559016 scopus 로고    scopus 로고
    • Loss of Cxcl12/Sdf-1 in adult mice decreases the quiescent state of hematopoietic stem/progenitor cells and alters the pattern of hematopoietic regeneration after myelosuppression
    • Tzeng YS, Li H, Kang YL, Chen WC, Cheng WC, Lai DM. Loss of Cxcl12/Sdf-1 in adult mice decreases the quiescent state of hematopoietic stem/progenitor cells and alters the pattern of hematopoietic regeneration after myelosuppression. Blood. 2011; 117(2): 429-39.
    • (2011) Blood , vol.117 , Issue.2 , pp. 429-439
    • Tzeng, Y.S.1    Li, H.2    Kang, Y.L.3    Chen, W.C.4    Cheng, W.C.5    Lai, D.M.6
  • 36
    • 18544379954 scopus 로고    scopus 로고
    • Stromal-derived factor-1 promotes the growth, survival, and development of human bone marrow stromal stem cells
    • Kortesidis A, Zannettino A, Isenmann S, Shi S, Lapidot T, Gronthos S. Stromal-derived factor-1 promotes the growth, survival, and development of human bone marrow stromal stem cells. Blood. 2005; 105(10): 3793-801.
    • (2005) Blood , vol.105 , Issue.10 , pp. 3793-3801
    • Kortesidis, A.1    Zannettino, A.2    Isenmann, S.3    Shi, S.4    Lapidot, T.5    Gronthos, S.6
  • 37
    • 84871683010 scopus 로고    scopus 로고
    • Stromal cellderived factor-1ffpotentiates bone morphogenetic protein-2-stimulated osteoinduction of genetically engineered bone marrowderived mesenchymal stem cells in vitro
    • Herberg S, Fulzele S, Yang N, Shi X, Hess M, Periyasamy-Thandavan S, et al. Stromal cellderived factor-1ffpotentiates bone morphogenetic protein-2-stimulated osteoinduction of genetically engineered bone marrowderived mesenchymal stem cells in vitro. Tissue Eng Part A. 2013; 19(1-2): 1-13.
    • (2013) Tissue Eng Part A , vol.19 , Issue.1-2 , pp. 1-13
    • Herberg, S.1    Fulzele, S.2    Yang, N.3    Shi, X.4    Hess, M.5    Periyasamy-Thandavan, S.6
  • 39
    • 2342473250 scopus 로고    scopus 로고
    • CD34+ progenitors from MDS patients are unresponsive to SDF-1, despite high levels of SDF-1 in bone marrow plasma
    • Matsuda M, Morita Y, Hanamoto H, Tatsumi Y, Maeda Y, Kanamaru A. CD34+ progenitors from MDS patients are unresponsive to SDF-1, despite high levels of SDF-1 in bone marrow plasma. Leukemia. 2004; 18(5): 1038-40.
    • (2004) Leukemia , vol.18 , Issue.5 , pp. 1038-1040
    • Matsuda, M.1    Morita, Y.2    Hanamoto, H.3    Tatsumi, Y.4    Maeda, Y.5    Kanamaru, A.6
  • 40
    • 84856147560 scopus 로고    scopus 로고
    • Endothelial and perivascular cells maintain haematopoietic stem cells
    • Ding L, Saunders TL, Enikolopov G, Morrison SJ. Endothelial and perivascular cells maintain haematopoietic stem cells. Nature. 2012; 481(7382): 457-62.
    • (2012) Nature , vol.481 , Issue.7382 , pp. 457-462
    • Ding, L.1    Saunders, T.L.2    Enikolopov, G.3    Morrison, S.J.4
  • 41
    • 84875682638 scopus 로고    scopus 로고
    • Expression of the melanoma cell adhesion molecule in human mesenchymal stromal cells regulates proliferation, differentiation, and maintenance of hematopoietic stem and progenitor cells
    • Stopp S, Bornhäuser M, Ugarte F, Wobus M, Kuhn M, Brenner S, Thieme S. Expression of the melanoma cell adhesion molecule in human mesenchymal stromal cells regulates proliferation, differentiation, and maintenance of hematopoietic stem and progenitor cells. Haematologica. 2013; 98(4): 505-13.
    • (2013) Haematologica , vol.98 , Issue.4 , pp. 505-513
    • Stopp, S.1    Bornhäuser, M.2    Ugarte, F.3    Wobus, M.4    Kuhn, M.5    Brenner, S.6    Thieme, S.7
  • 43
    • 77951962617 scopus 로고    scopus 로고
    • Co-culture with mesenchymal stromal cells increases proliferation and maintenance of haematopoietic progenitor cells
    • Walenda T, Bork S, Horn P, Wein F, Saffrich R, Diehlmann A, et al. Co-culture with mesenchymal stromal cells increases proliferation and maintenance of haematopoietic progenitor cells. J Cell Mol Med. 2010; 14(1-2): 337-50.
    • (2010) J Cell Mol Med , vol.14 , Issue.1-2 , pp. 337-350
    • Walenda, T.1    Bork, S.2    Horn, P.3    Wein, F.4    Saffrich, R.5    Diehlmann, A.6
  • 44
    • 84864387249 scopus 로고    scopus 로고
    • Primary mesenchymal stem and progenitor cells from bone marrow lack expression of CD44 protein
    • Quian H, Le Blanc K, Sigvardsson M. Primary mesenchymal stem and progenitor cells from bone marrow lack expression of CD44 protein. J Biol Chem. 2012; 287: 25795-807.
    • (2012) J Biol Chem , vol.287 , pp. 25795-25807
    • Quian, H.1    Le Blanc, K.2    Sigvardsson, M.3
  • 45
    • 60249093589 scopus 로고    scopus 로고
    • Stroma-dependent apoptosis in clonal hematopoietic precursors correlates with expression of PYCARD
    • Mhyre AJ, Marcondes AM, Spaulding EY, Deeg HJ. Stroma-dependent apoptosis in clonal hematopoietic precursors correlates with expression of PYCARD. Blood. 2009; 113(3): 649-58.
    • (2009) Blood , vol.113 , Issue.3 , pp. 649-658
    • Mhyre, A.J.1    Marcondes, A.M.2    Spaulding, E.Y.3    Deeg, H.J.4
  • 46
    • 77950925065 scopus 로고    scopus 로고
    • Lenalidomide induces cell death in an MDSderived cell line with deletion of chromosome 5q by inhibition of cytokinesis
    • Matsuoka A, Tochigi A, Kishimoto M, Nakahara T, Kondo T, Tsujioka T, et al. Lenalidomide induces cell death in an MDSderived cell line with deletion of chromosome 5q by inhibition of cytokinesis. Leukemia. 2010; 24(4): 748-55.
    • (2010) Leukemia , vol.24 , Issue.4 , pp. 748-755
    • Matsuoka, A.1    Tochigi, A.2    Kishimoto, M.3    Nakahara, T.4    Kondo, T.5    Tsujioka, T.6
  • 47
    • 51049087523 scopus 로고    scopus 로고
    • Osteoprogenitor differentiation is not affected by immunomodulatory thalidomide analogs but is promoted by low bortezomib concentration, while both agents suppress osteoclast differentiation
    • Munemasa S, Sakai A, Kuroda Y, Okikawa Y, Katayama Y, Asaoku H, et al. Osteoprogenitor differentiation is not affected by immunomodulatory thalidomide analogs but is promoted by low bortezomib concentration, while both agents suppress osteoclast differentiation. Int J Oncol. 2008; 33(1): 129-36.
    • (2008) Int J Oncol , vol.33 , Issue.1 , pp. 129-136
    • Munemasa, S.1    Sakai, A.2    Kuroda, Y.3    Okikawa, Y.4    Katayama, Y.5    Asaoku, H.6
  • 48
    • 77953090345 scopus 로고    scopus 로고
    • CXCL12 (SDF-1)/CXCR4 pathway in cancer
    • Teicher BA, Fricker SP. CXCL12 (SDF-1)/CXCR4 pathway in cancer. Clin Cancer Res. 2010; 16(11): 2927-31.
    • (2010) Clin Cancer Res , vol.16 , Issue.11 , pp. 2927-2931
    • Teicher, B.A.1    Fricker, S.P.2
  • 49
    • 67650410440 scopus 로고    scopus 로고
    • Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100
    • Nervi B, Ramirez P, Rettig MP, Uy GL, Holt MS, Ritchey JK, et al. Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100. Blood. 2009; 113(24): 6206-14.
    • (2009) Blood , vol.113 , Issue.24 , pp. 6206-6214
    • Nervi, B.1    Ramirez, P.2    Rettig, M.P.3    Uy, G.L.4    Holt, M.S.5    Ritchey, J.K.6
  • 50
    • 77949699420 scopus 로고    scopus 로고
    • Effect of lenalidomide therapy on hematopoiesis of patients with myelodysplastic syndrome associated with chromosome 5q deletion
    • Ximeri M, Galanopoulos A, Klaus M, Parcharidou A, Giannikou K, Psyllaki M, et al. Effect of lenalidomide therapy on hematopoiesis of patients with myelodysplastic syndrome associated with chromosome 5q deletion. Haematologica. 2010; 95(3): 406-14.
    • (2010) Haematologica , vol.95 , Issue.3 , pp. 406-414
    • Ximeri, M.1    Galanopoulos, A.2    Klaus, M.3    Parcharidou, A.4    Giannikou, K.5    Psyllaki, M.6


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